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Carcinoma, EndometrioidEndometrial NeoplasmsCarcinomaAdenocarcinoma, Clear CellCystadenocarcinoma, SerousOvarian NeoplasmsCarcinoma, Squamous CellCarcinoma, HepatocellularCystadenocarcinoma, PapillaryEndometrial HyperplasiaImmunohistochemistryAdenocarcinoma, MucinousTumor Markers, BiologicalCarcinoma, PapillaryCarcinoma in SituMixed Tumor, MullerianUterine NeoplasmsHysterectomyNeoplasm StagingEndometriosisAdenocarcinomaPrognosisCarcinosarcomaNeoplasm InvasivenessLiver NeoplasmsGene Expression Regulation, NeoplasticTissue Array AnalysisCarcinoma, Ductal, BreastCarcinoma, AdenosquamousPTEN PhosphohydrolaseCarcinoma, Basal CellNeoplasms, Glandular and EpithelialCystadenocarcinoma, MucinousDilatation and CurettageEndometriumNeoplasm GradingNeoplasms, Cystic, Mucinous, and SerousOvarian CystsCell Line, TumorCarcinoma, Transitional CellDNA, NeoplasmNeoplasms, Multiple Primarybeta CateninLymphatic MetastasisSalpingectomyCarcinoma, BronchogenicTumor Suppressor Protein p53Carcinoma, Intraductal, NoninfiltratingCarcinoma, Adenoid CysticEpididymal Secretory ProteinsMicrosatellite InstabilityCarcinoma, Small CellImmunoenzyme TechniquesCarcinoma, MedullaryRetrospective StudiesSurvival RateCarcinoma, LobularPrecancerous ConditionsNeoplasm ProteinsMutationNeoplasm Recurrence, LocalCell Transformation, NeoplasticCarcinoma, NeuroendocrineUrethral NeoplasmsSurvival AnalysisNasopharyngeal NeoplasmsThyroid NeoplasmsBreast NeoplasmsDisease-Free SurvivalTumor Cells, CulturedRNA, MessengerLung NeoplasmsLoss of HeterozygosityCarcinoma, MucoepidermoidDNA Mutational AnalysisMitotic IndexOligonucleotide Array Sequence AnalysisUterine Cervical NeoplasmsMixed Tumor, MesodermalReverse Transcriptase Polymerase Chain ReactionHead and Neck NeoplasmsGenes, Tumor SuppressorKaplan-Meier EstimateTreatment OutcomeGene Expression ProfilingCarcinoma, EmbryonalEsophageal NeoplasmsMouth NeoplasmsCarcinoma, Merkel CellReceptors, ProgesteroneCarcinoma, DuctalDisease ProgressionMicrosatellite RepeatsCA-125 AntigenAntigens, Tumor-Associated, CarbohydrateAdrenocortical CarcinomaColonic NeoplasmsCarcinoma, VerrucousCarcinoma, Signet Ring CellReceptors, Estrogen
AdenocarcinomaEpithelial tumorsHistologicEndometriumMorphologicCancersAdenocarcinomasHistologySerous-endometrioidHigh-grade serous ovarianInclude high-grade serousOvaryRenal cell carcIntraepithelial carcinomasCervixMalignantMetastasesAriseMutations2022Squamous cellBorderlineLesionsNeoplasmsGradeClear cellMorphologyPeritonealChemotherapySurvivalPapillaryEndometriosisGynecologicSetting of endometrialTumourAtypia
Adenocarcinoma7
Epithelial tumors4
  • Carcinoma of cervix is classified as per the WHO classification into primary tumors which are predominantly epithelial tumors, mesenchymal tumors and tumor like lesions, mixed epithelial stromal tumors, melanocytic, germ cell, and lymphoid tumors. (cytojournal.com)
  • Squamous cell carcinoma (SCC) in various morphological forms needs to be separated from other epithelial tumors for treatment modality selection. (cytojournal.com)
  • Cancerous epithelial tumors are carcinomas. (news-medical.net)
  • However, the vast majority of malignant ovarian tumors (80%-85%) are classified as epithelial tumors (carcinomas). (biomedcentral.com)
Histologic2
Endometrium6
Morphologic2
  • Tumors located in central portions of the prostate are, in our opinion, morphologic variants of usual prostatic carcinomas, and apparently arise in prostatic ducts. (nih.gov)
  • However, as explained below, recent morphologic findings and molecular analyses have demonstrated that each morphologic subtype of ovarian carcinoma might be derived from a Müllerian-type epithelium. (biomedcentral.com)
Cancers11
  • Epithelial carcinoma makes up 85% to 90% of ovarian/fallopian tube cancers. (cancer.net)
  • 10 ] Further, among carriers of deleterious mutations in BRCA1 or BRCA2, increasing evidence suggests that many tumors previously classified as ovarian high-grade serous carcinoma may develop from malignant cells arising in the tubal epithelium (serous tubal intraepithelial carcinoma [STIC]), although these tumors continue to be referred to as ovarian cancers in most writings. (uofmhealth.org)
  • Based on the model of development of serous tubal intraepithelial carcinomas, there are several theories or pathways by which serous cancers metastasize. (ascopost.com)
  • Epithelial ovarian carcinomas (EOC's) account for 85 to 90 percent of all cancers of the ovaries. (news-medical.net)
  • We report herein the newly described molecular abnormalities in epithelial ovarian cancers (carcinomas). (biomedcentral.com)
  • Endometrioid adenocarcinomas account for about 75 to 80% of endometrial cancers. (msdmanuals.com)
  • L'objectif de cette étude était de déterminer la fréquence des cancers gynécologiques en pratique oncologique à Lomé et d'en étudier les aspects épidémiologiques et histo-cliniques. (bvsalud.org)
  • Il s'agitd'une étude rétrospective et descriptive portant sur tous les cancers gynécologiques reçus en oncologie entre le 1erJanvier 2016 et le 31 Décembre 2021. (bvsalud.org)
  • ces cancers ont ete diagnostiques au stade avance d'ou les difficultes dans leur prise en charge chirurgicale. (bvsalud.org)
  • En consequence notre objectif a ete d'etudier la place et les caracteres de la chirurgie dans la prise en charge de ces cancers. (bvsalud.org)
  • [ 1 ] Most endometrial cancers are of endometrioid type and are associated with exposure to unopposed estrogen . (medscape.com)
Adenocarcinomas2
  • Results: The preoperative biopsies were all typical ovarian serous or endometrioid adenocarcinomas. (bmj.com)
  • Approximately eighty percent of endometrial carcinomas are endometrioid adenocarcinomas. (medscape.com)
Histology2
  • Type II tumors are usually high-grade and include grade 3 endometrioid carcinomas and tumors with nonendometrioid histology (eg, serous, clear cell, mixed cell, undifferentiated, carcinosarcoma). (msdmanuals.com)
  • Patients with endometrioid cancer and grade 1 or 2 histology localized to the uterus may undergo hysterectomy only and require no extensive dissection of lymph nodes. (medscape.com)
Serous-endometrioid1
  • Participant must have histologically documented, platinum resistant, advanced (metastatic and/or unresectable) high-grade serous/endometrioid ovarian, primary peritoneal, or fallopian tube cancer. (uclahealth.org)
High-grade serous ovarian1
  • Because of their common features, high-grade serous ovarian, fallopian tube, and peritoneal carcinomas are considered one clinical entity and referred to as a single entity (epithelial ovarian carcinoma or high-grade serous ovarian cancer). (ascopost.com)
Include high-grade serous1
  • Type II tumors include high-grade serous carcinoma, malignant mixed mesodermal tumors, and undifferentiated carcinomas. (hindawi.com)
Ovary3
  • subsequently, this group of tumors of the ovary were classified in 1973 by the World Health Organization as "low malignant potential ovarian tumor" [ 2 ] and, finally, in 2003 WHO separates them from carcinomas and call them borderline tumors. (intechopen.com)
  • Reported rates of mucinous carcinoma diagnoses have declined dramatically, but expert pathology reviews suggest that this reflects increased recognition of metastases from occult gastrointestinal primary tumors to the ovary, rather than a true decline in rates of ovarian primary tumors. (uofmhealth.org)
  • Carcinoma of the ovary is most common in women over age 60. (news-medical.net)
Renal cell carc1
  • Without immunohistological analysis, it is difficult to distinguish this HCC variant from clear cell carcinoma or metastases of renal cell carcinoma. (karger.com)
Intraepithelial carcinomas3
  • The intraepithelial carcinomas have been referred to as serous intraepithelial carcinomas (STICs) but our own findings (unpublished data) and recent reports have drawn attention to a spectrum of changes that fall short of STICs that we have designated serous tubal intraepithelial lesions (STILs). (hindawi.com)
  • Early investigators reported on serous tubal intraepithelial carcinomas, which developed in the distal fallopian tubes. (ascopost.com)
  • Findings revealed that 59% to 71% were associated with serous tubal intraepithelial carcinomas after careful inspection of the fallopian tubes. (ascopost.com)
Cervix3
  • however, in developing countries, it is much less common than carcinoma of the cervix. (medscape.com)
  • Nonmelanotic skin cancer or carcinoma-in-situ of the cervix, or prostate or localized endometrioid endometrial cancer. (mayo.edu)
  • Carcinoma cervix is not the only cancer caused by HPV. (cytojournal.com)
Malignant2
  • Unlike the invasive carcinomas, borderline ovarian tumors are characterized by cytoplasmic and nuclear atypia, (element of differential diagnosis with benign tumors), absence of stromal invasion, (element of differential diagnosis with malignant tumors), unusual degree of proliferation of the epithelial cells with cellular stratification including remarkable architectural atypia and the formation of papillary protuberances. (intechopen.com)
  • The category of ovarian borderline tumor or tumor of low-malignant potential, which historically had been considered in the context of ovarian cancer, is now generally considered a nonmalignant entity, although it has a postulated relationship with the development of some histological subtypes of low-grade ovarian carcinomas. (uofmhealth.org)
Metastases2
  • In a second pathway, the serous tubal intraepithelial carcinoma metastasizes directly into the peritoneal cavity, seeding it and resulting in early dissemination of metastases. (ascopost.com)
  • Lymphovascular space invasion as a predictive factor for lymph node metastases and survival in endometrioid endometrial cancer - a Swedish Gynecologic Cancer Group (SweGCG) study. (cancercentrum.se)
Arise1
  • Both clear cell ovarian carcinomas (CCC) and ovarian endometrioid carcinomas (EC) may arise from endometriosis and frequently harbor mutations in the ARID1A tumor suppressor gene. (biomedcentral.com)
Mutations1
  • It is hypothesized that high-grade serous carcinomas among individuals who are not carriers of mutations in BRCA1 or BRCA2 may also develop in the fallopian tube, but few STICs have been identified among these women in the absence of concurrent high-stage disease. (uofmhealth.org)
20221
  • Spatial expression of the FGFR2b splice isoform and its prognosticsignificance in endometrioid endometrial carcinoma (2022) Asmerom T Sengal, Deborah Smith, Cameron E Snell, Samuel Leung, Aline Talhouk, Elizabeth D Williams, Jessica N McAlpine and Pamela M Pollock. (edu.au)
Squamous cell2
  • Immunohistochemical analysis of paraffin-embedded human squamous cell lung carcinoma using Btk (D3H5) Rabbit mAb performed on the Leica ® Bond ™ Rx. (cellsignal.com)
  • Primary treatment and relative survival by stage and age in vulvar squamous cell carcinoma: A population-based SweGCG study. (cancercentrum.se)
Borderline1
  • The first (Type I) pathway leads to borderline tumors, which can develop into low-grade serous, mucinous, endometrioid, and clear cell carcinomas. (hindawi.com)
Lesions1
  • The lack of proven screening tools for early detection and the high mortality of ovarian serous carcinoma (OSC), particularly high grade, have focused attention on identifying putative precursor lesions with distinct morphological and molecular characteristics. (hindawi.com)
Neoplasms2
  • They are part of the surface epithelial tumor group of ovarian neoplasms (10-20% of which are the endometrioid type). (wikipedia.org)
  • A stepwise model of progression from cystadenomas to low-grade carcinomas has been proposed for these neoplasms. (hindawi.com)
Grade10
  • Risk Stratification of Stage I Grade 3 Endometrioid Endometrial Carcinoma in the Era of Molecular Classification. (bvsalud.org)
  • The role of adjuvant therapy in stage I grade 3 endometrioid endometrial carcinoma ( EEC ) is debatable. (bvsalud.org)
  • Objectives To assess the effects on relative survival of established and new prognostic factors in stage I-III grade 1-3 endometrioid endometrial carcinoma and in the subgroup of stage I grade 1-2. (bmj.com)
  • Methods This was a population-based, retrospective study including all women (n=1113) in the western Swedish healthcare region diagnosed with International Federation of Gynecology and Obstetrics (FIGO) stage I-III grade 1-3 endometrioid endometrial carcinoma in 2006-2011. (bmj.com)
  • Conclusion We can conclude that S-phase fraction, DNA ploidy, and p53 overexpression did not improve identification of high-risk patients by stage, grade, and age in stage I-III endometrioid endometrial carcinoma. (bmj.com)
  • It is estimated that 60% of sporadic ovarian carcinomas and the majority of those diagnosed in BRCA1 mutation carriers are of the high-grade serous type [ 4 , 5 ]. (hindawi.com)
  • Ovarian carcinomas consist of several histopathological types, with high-grade serous being both the most common and most lethal. (uofmhealth.org)
  • Further, data suggest that the distinction of high-grade serous carcinomas from other histological types of high-grade carcinomas, particularly endometrioid carcinomas, is not reliable. (uofmhealth.org)
  • The discovery of a serous tubal intraepithelial carcinoma imposes a later risk of high-grade serous cancer. (ascopost.com)
  • This small percentage includes patients with stage IA or IB (grade 1) serous, mucinous, endometrioid, and Brenner tumors. (medscape.com)
Clear cell5
  • Here, we report an unusual combination of bilateral ovarian SMBT and clear cell carcinoma associated with polypoid endometriosis of the colon, in a 62-year-old woman. (hindawi.com)
  • To the best of our knowledge, this is the first case of this unusual combination of ovarian seromucinous tumor and clear cell carcinoma to be reported in the English literature. (hindawi.com)
  • Here, we describe the first case, to our knowledge, of an unusual combination of ovarian SMBT and clear cell carcinoma. (hindawi.com)
  • Histologically, most of them are serous or mucinous, but endometrioid, clear cell, Brenner (transitional cell) or mixed histotypes can be also seen. (intechopen.com)
  • The association of endometriosis with ovarian cancer is stronger for nonserous subtypes, especially clear cell carcinoma and endometrioid subtypes. (uofmhealth.org)
Morphology1
  • Ovarian carcinomas are characterized by a Müllerian morphology although the ovaries do not originate from the Müllerian ducts. (biomedcentral.com)
Peritoneal3
  • Staging of endometrial carcinoma is based on the FIGO staging system, which is a surgical and pathological staging following total abdominal hysterectomy , salpingo-oophorectomy, lymphadenectomy, and peritoneal washings. (radiopaedia.org)
  • However, it is not known whether the precursor cells from the serous tubal intraepithelial carcinoma implant on the peritoneal surface or float freely in the peritoneal fluid prior to undergoing a pivotal genomic change, resulting in tumor development. (ascopost.com)
  • Serous carcinomas are thought to be derived from the fallopian tubes through foci of endosalpingiosis, which are inclusion cysts from the tubal epithelium at the ovarian and peritoneal surface. (biomedcentral.com)
Chemotherapy3
  • Aims: Traditionally, advanced stage ovarian carcinoma is treated by debulking surgery followed by chemotherapy. (bmj.com)
  • This study aims to describe the morphological features found in ovarian carcinoma after chemotherapy because these have not been detailed previously. (bmj.com)
  • Methods: Histological sections were examined from 18 cases of ovarian carcinoma that had been treated by preoperative chemotherapy. (bmj.com)
Survival1
  • OBJECTIVES: I. Evaluate the efficacy of paclitaxel and carboplatin with amifostine on progression free survival and overall survival in patients with metastatic or recurrent epithelial endometrial carcinoma not amenable to surgery or radiotherapy. (knowcancer.com)
Papillary2
  • Fifty carcinomas that were partially to completely papillary in nature were examined. (nih.gov)
  • We conclude that a distinction between endometrioid carcinomas and tumors of prostatic ducts does not seem justified and that papillary prostatic carcinomas should be treated like common prostatic cancer. (nih.gov)
Endometriosis1
Gynecologic1
  • We sought to define the agreement between Post Operative Radiation Therapy in Endometrial Carcinoma 1 (PORTEC-1) high-intermediate risk (HIR) and Gynecologic Oncology Group (GOG)-99 HIR criteria, assess their concordance with The Cancer Genome Atlas molecular subtypes, and evaluate oncologic outcomes in this population . (bvsalud.org)
Setting of endometrial1
  • Type II (20%) arises in the setting of endometrial atrophy, in females between 65 to 75 years old, and endometrial intraepithelial carcinoma. (radiopaedia.org)
Tumour1
  • Similarly, under Carcinoma, specific renamed or deleted in later revisions of tumour classifications. (who.int)
Atypia1
  • Carcinomas are characterized by cell proliferation, nuclear atypia, and stromal invasion. (biomedcentral.com)