• Of all histologic types of lung cancer, SCLC and squamous cell carcinoma have the strongest correlation to tobacco. (medscape.com)
  • More than 99% of primary lung cancers are carcinoma, which are tumors composed of cells that originate from embryonic ectoderm or endoderm, or that feature epithelial characteristics or differentiation. (wikipedia.org)
  • Carcinomas of the lung are thought to arise from the uncontrolled growth of mutated, transformed, multipotent "cancer stem cells" with epithelial characteristics or lineage. (wikipedia.org)
  • and (b) those of epithelial type, which include neuroendocrine neoplasms from many sites. (basicmedicalkey.com)
  • Neuroendocrine lung tumors can be grouped into four epithelial and one mesenchymal tumor. (deepdyve.com)
  • The epithelial neuroendocrine tumors are further divided into two high-grade carcinomas, large and small cell neuroendocrine carcinomas, and into low-grade typical and intermediate grade atypical carcinoid. (deepdyve.com)
  • The only non-epithelial neuroendocrine tumor of the lung is pulmonary paraganglioma. (deepdyve.com)
  • The tumor had invaded the adjacent pancreatic tissues. (springer.com)
  • Cytomorphologic, immunophenotypical and molecular features of pancreatic acinar cell carcinoma Sun T, Gilani S, Jain D, Cai G. Cytomorphologic, immunophenotypical and molecular features of pancreatic acinar cell carcinoma. (yale.edu)
  • For treatment of neuroendocrine cancers (i.e., carcinoid tumors and pancreatic endocrine tumors) involving the liver. (aetna.com)
  • Chemoembolization (CE) for other indications including palliative treatment of liver metastases from other non-neuroendocrine primaries (e.g., breast cancer, cervical cancer, colon cancer, esophageal cancer, melanoma, rhabdomyosarcoma, or unknown primaries) and CE of the pancreas for pancreatic cancer. (aetna.com)
  • elevated human chorionic gonadotropin and pancreatic polypeptide levels are occasionally present with carcinoids. (msdmanuals.com)
  • The present consensus statement was developed collaboratively by the North American Neuroendocrine Tumor Society (NANETS) and the Society of Nuclear Medicine and Molecular Imaging (SNMMI). (snmjournals.org)
  • The North American Neuroendocrine Tumor Society Consensus Guidelines for Surveillance and Medical Management of Midgut Neuroendocrine Tumors. (ucsf.edu)
  • Immunotherapy with dendritic cells and/or cytokine-induced killer cells for the treatment of hepatocellular carcinoma. (aetna.com)
  • Hepatocellular carcinoma (HCC) was considered based on the image findings and underlying HBV infection. (biomedcentral.com)
  • PHCT presents as a small and single nodule, is extremely rare and is difficult to differentiate from hepatocellular carcinoma (HCC), particularly in a region with high prevalence of HCC. (biomedcentral.com)
  • Are prophylactic antibiotics necessary prior to transarterial chemoembolization for hepatocellular carcinoma in patients with native biliary anatomy? (thieme-connect.com)
  • Antibiotic prophylaxis in transarterial therapy of hepatocellular carcinoma: a meta-analysis. (thieme-connect.com)
  • Dexamethasone prophylaxis to alleviate postembolization syndrome after transarterial chemoembolization for hepatocellular carcinoma: a randomized, double-blinded, placebo-controlled study. (thieme-connect.com)
  • A predictive model for postembolization syndrome after transarterial hepatic chemoembolization of hepatocellular carcinoma. (thieme-connect.com)
  • The procedure is typically used to treat hepatocellular carcinoma (primary liver cancer), or metastasis (secondary liver cancer) from other types of cancers. (doctorsimaginggroup.com)
  • Treatment focuses on control of the underlying carcinoid syndrome, targeting subsequent valvular heart disease and managing consequent heart failure. (karger.com)
  • Some liver metastases treated include: neuroendocrine including carcinoid, gastrointestinal stromal tumors, melanoma, breast and colon. (doctorsimaginggroup.com)
  • Atypical Carcinoid Tumor Versus Large-Cell Neuroendocrine Carcinoma Yoon E, Cai G . Atypical Carcinoid Tumor Versus Large-Cell Neuroendocrine Carcinoma. (yale.edu)
  • Background/aim: Large-cell neuroendocrine carcinoma (LCNEC) of the lung is a relatively uncommon and aggressive subset of pulmonary neuroendocrine tumors, which include typical and atypical carcinoid, and small-cell lung cancer. (tubitak.gov.tr)
  • range 48 to 77 years) who underwent pulmonary resection for large-cell neuroendocrine carcinoma between January 2004 and December 2014 were investigated retrospectively. (tubitak.gov.tr)
  • Heterogeneous Tumor-Immune Microenvironments between Primary and Metastatic Tumors in a Patient with ALK Rearrangement-Positive Large Cell Neuroendocrine Carcinoma. (go.jp)
  • The multicentre cohort included 58 typical carcinoids (TC), 42 atypical carcinoids (AC), 32 large cell neuroendocrine carcinomas (LCNEC) and 60 small cell lung carcinomas (SCLC). (biomedcentral.com)
  • Lung neuroendocrine tumors (NET) comprise the four histotypes typical carcinoid (TC), atypical carcinoid (AC), large cell neuroendocrine carcinoma (LCNEC) and small cell lung carcinoma (SCLC). (biomedcentral.com)
  • Neuroendocrine Tumors of the Bronchopulmonary System (Typical and Atypical Carcinoid Tumors): Current Strategies in Diagnosis and Treatment. (karger.com)
  • Small-Cell Carcinoma Versus Atypical Carcinoid Tumor Yoon E, Zhang X, Cai G . Small-Cell Carcinoma Versus Atypical Carcinoid Tumor. (yale.edu)
  • Low dose radiation to lung tumors about a year ago is still having a beneficial effect on Atypical lung lesions. (mayoclinic.org)
  • Carcinoids are further divided into atypical and typical, based on mitotic count and presence of necrosis. (who.int)
  • The optimal management of patients with carcinoid tumors involves a multidisciplinary team of health care providers including an oncologist, gastroenterologist, surgeon, radiologist and nuclear medicine specialist. (medifocus.com)
  • Advances in the management of patients with carcinoid syndrome. (harvard.edu)
  • [ 6 ] In its 2015 consensus statement on best practices for pulmonary neuroendocrine tumors, the ENETS noted that tumor grading based on a combination of KI-67, mitotic rate, and necrosis may be of clinical importance but lacks validation. (medscape.com)
  • ZS E Rassi RM Mohsine F Berger P Thierry CC-M Partensky (2004) ArticleTitle Endocrine tumors of the extrahepatic bile duct. (springer.com)
  • In addition to multidisciplinary approaches, every effort should be made to follow the recommendations and guidelines issued by national (the French Group of Endocrine Tumors) and international groups. (nih.gov)
  • Although rhabdoid variants of LCLC are sometimes referred to as "rhabdoid carcinomas", this particular term should be reserved for examples of "pure" rhabdoid neoplasms (i.e. those that do not contain cells containing other histological variants) Lung cancers are now considered a large and extremely heterogeneous family of neoplasms that feature widely varying genetic, biological, and clinical characteristics. (wikipedia.org)
  • Carcinoid tumors are the most common appendix cancers, making up about half of those diagnosed. (mskcc.org)
  • Merkel cell carcinoma , a rare neuroendocrine virus-linked skin cancer, has been added to the list of cancers that can be treated by immunotherapy. (carcinoid.org)
  • Small cell lung cancer (SCLC), previously known as oat cell carcinoma, is considered distinct from other lung cancers, which are called non-small cell lung cancers (NSCLCs) because of their clinical and biologic characteristics. (medscape.com)
  • Lung cancers are generally classified into three types: small cell, non-small cell and lung carcinoid tumour. (myupchar.com)
  • By immunohistochemistry assay, studies showed that loss of Rb occurred almost universally in prostatic small cell carcinomas. (healthyprostateclub.com)
  • These data suggest that Rb loss is a critical event in the development of small cell carcinomas and may be a useful diagnostic and potential therapeutic target. (healthyprostateclub.com)
  • Small-cell carcinomas are stimulated by bombesin/GRP and related peptides and contain receptors for them. (cancernetwork.com)
  • Carcinoid tumors and small-cell carcinomas of the gallbladder and extrahepatic bile ducts: a comparative study based on 221 cases from the Surveillance, Epidemiology, and End Results Program. (cancercentrum.se)
  • Rhabdoid cells often express protein products suggestive of aggressive, dedifferentiated cells, including neuroendocrine tumor-related products and granulocyte-macrophage colony stimulating factor (GM-CSF). (wikipedia.org)
  • Over the years it became clear that carcinoid tumors can be quite aggressive, can metastasize, and can cause carcinoid syndrome . (medifocus.com)
  • SCLC is a neuroendocrine carcinoma that exhibits aggressive behavior, rapid growth, early spread to distant sites, exquisite sensitivity to chemotherapy and radiation, and frequent association with distinct paraneoplastic syndromes, including hypercalcemia, Eaton-lambert syndrome, syndrome of inappropriate diuretic hormone, and many others. (medscape.com)
  • Thus, neuroendocrine-specific growth factors such as bombesin represent novel therapeutic targets and may also be important in the selection of patients for aggressive chemotherapy, which has been rather ineffective in prostate cancer. (cancernetwork.com)
  • Sometimes known as an adenoneurocrine tumor, goblet cell carcinomas are more aggressive than other appendix tumors and may spread to other organs. (immunitytherapycenter.com)
  • Without treatment, SCLC has the most aggressive clinical course of any type of pulmonary tumor, with a median survival from diagnosis of only 2 to 4 months. (cancer.gov)
  • Pulmonary carcinoids are well differentiated low to intermediate grade lung neuroendocrine tumours (LNETs), that belong to the group of lung neuroendocrine neoplasms which also include highly aggressive lung neuroendocrine carcinomas (LNECs). (who.int)
  • ParetoTI theory identified four tumour archetypes within the tetrahedron, corresponding to the three previously reported molecular groups, and the fourth enriched for the aggressive supra-carcinoids. (who.int)
  • More importantly, given the rise and progress in molecular pathology particularly in fields such as pulmonary adenocarcinomas, it is of great current interest to know any molecular variations in post ADT neuroendocrine differentiation and pure NEPC. (healthyprostateclub.com)
  • To address this aim we have designed the lungNENomics study, an international cohort of over 250 cases of pulmonary carcinoids, with clinical data and central pathology review, as well as whole-genome sequencing, RNA sequencing, DNA methylation array, and digital spatial profiling data. (who.int)
  • LCNECs show features of high-grade neuroendocrine tumors and patients with LCNEC have a very poor prognosis. (tubitak.gov.tr)
  • Patients with carcinoids were predominantly female and 10 years younger than patients with LCNEC/SCLC. (biomedcentral.com)
  • In comparison to the carcinoids, LCNEC/SCLC tumors presented a stronger loss of nuclear and cytosolic PTEN associated with a loss of PTEN and p53 . (biomedcentral.com)
  • Multiple endocrine neoplastic type 2 is a rare genetic syndrome, characterized by the familial occurrence of medullary thyroid carcinoma either isolated or associated with pheochromocytoma, primary hyperparathyroidism, or typical features (Marfanoid habitus, mucosal neuromas). (nih.gov)
  • In MEN2, calcitonin and carcinoembryonic antigen (CEA) serve as excellent tumor markers for medullary thyroid carcinoma. (nih.gov)
  • Small cell lung carcinoma (SCLC) arises in peribronchial locations and infiltrates the bronchial submucosa. (medscape.com)
  • SCLC accounts for approximately 15% of bronchogenic carcinomas. (cancer.gov)
  • At the time of diagnosis, approximately 30% of patients with SCLC will have tumors confined to the hemithorax of origin, the mediastinum, or the supraclavicular lymph nodes. (cancer.gov)
  • Diagnosis of acinic cell carcinoma of the salivary gland on cytology specimens: Role of NOR‐1 (NR4A3) immunohistochemistry Meiklejohn K, Hrones M, Wang M, Prasad M, Cai G , Adeniran A, Gilani S. Diagnosis of acinic cell carcinoma of the salivary gland on cytology specimens: Role of NOR‐1 (NR4A3) immunohistochemistry. (yale.edu)
  • Most carcinoid tumors are now known to be slow growing malignant tumors that have their own specific biological and clinical characteristics. (medifocus.com)
  • According to the American Society of Clinical Oncology (ASCO), approximately 11,500 people in the United States are diagnosed each year with a carcinoid tumor. (medifocus.com)
  • Subjects with clinical MEN1 and those who carry a mutation in the MEN1 gene should be offered biochemical and imaging screening in order to detect tumors and evaluate their progression over time. (nih.gov)
  • Clinical Implications and Molecular Characterization of Drebrin-Positive, Tumor-Infiltrating Exhausted T Cells in Lung Cancer. (go.jp)
  • Recent developments in technology may make the monitoring of changes in patients' tumour genotypes easier in clinical practice, which may enable patients' treatment regimens to be tailored during the course of their disease, potentially leading to improved patient outcomes. (bmj.com)
  • The intent was to treat all patients because of uncontrolled tumor disease ( n = 21), contraindication to chemotherapy or surgery ( n = 7), or uncontrolled and badly tolerated clinical symptoms ( n = 4). (snmjournals.org)
  • Pejorative events were defined as side effects due to therapy, relapse in clinical symptoms, tumor progression, tumor laboratory marker increase, and death. (snmjournals.org)
  • This review will examine the evidence for the neuroendocrine progression of prostate cancer and the clinical utility of chemothera- peutic agents that are being investigated for the management of late stage disease. (cancernetwork.com)
  • Combined with observations of neuroendocrine enrichment in cases of poor clinical response to androgen deprivation therapy, these findings support the notion that the clonal expansion of AR-negative neuroendocrine cells may play a critical role in the development of androgen-insensitive metastatic prostate cancer. (cancernetwork.com)
  • The clinical relevance of immunohistological detection of neuroendocrine tissue in prostate cancer patients has been the focus of many investigators. (cancernetwork.com)
  • Have you asked your cancer team if you may be eligible for any clinical trials for stage 4 neuroendocrine cancer? (mayoclinic.org)
  • Additionally, we identified six tumours, termed supra-carcinoids, that displayed genuine carcinoid-like morphology, but had clinical and molecular characteristics of LNECs. (who.int)
  • The focus of our work is to better understand the biological and clinical characteristics of these molecular groups of carcinoids. (who.int)
  • Endocrinologically active tumors of the diffuse peripheral endocrine or paracrine system (neuroendocrine tumors) produce various amines and polypeptides with corresponding symptoms and signs, including carcinoid syndrome. (msdmanuals.com)
  • The World Health Organization (WHO) and the European Neuroendocrine Tumor Society (ENETS) both incorporate mitotic count and Ki-67 proliferation for the classification of gastroenteropancreatic NETs (GEP-NETs). (medscape.com)
  • These are less common tumors, which, despite the name, are not carcinoid tumors or NETs. (mskcc.org)
  • In this document, we review the literature on the use of 177 Lu-DOTATATE in neuroendocrine tumors (NETs) of different primary origin, discuss issues of controversy, and review potential contraindications to treatment. (snmjournals.org)
  • Go to the Neuroendocrine Tumors (NETs) Support Group. (mayoclinic.org)
  • However, carcinoid tumor cells are distinguished from most other types of tumors in that they secrete various hormone-like substances (e.g., serotonin, noradrenalin, histamines) which may cause symptoms throughout the body rather than symptoms localized to the organ where the tumor originates. (medifocus.com)
  • Carcinoid syndrome describes a combination of symptoms that result from hormones or hormone-like substances, (e.g., serotonin, gastrin, ACTH) that are produced by some carcinoid tumors. (medifocus.com)
  • Symptoms are caused by tumor secretion of serotonin, prostaglandins, and other biologically active substances. (harvard.edu)
  • The pathophysiology of CHD is related to vasoactive substances secreted by the tumor, of which serotonin is most prominent in the pathophysiology of CHD. (karger.com)
  • Carcinoid tumors are neuroendocrine origin neoplasm and may produce serotonin or other functional peptide hormones. (biomedcentral.com)
  • The syndrome results from vasoactive substances (including serotonin , bradykinin, histamine, prostaglandins, polypeptide hormones) secreted by the tumor, which is typically a metastatic intestinal carcinoid. (msdmanuals.com)
  • An intestinal carcinoid does not usually cause carcinoid syndrome unless hepatic metastases have occurred because metabolic products released by the tumor are rapidly destroyed by blood and liver enzymes in the portal circulation (eg, serotonin by hepatic monoamine oxidase). (msdmanuals.com)
  • Serotonin , the primary hormone produced by carcinoid tumors, acts on smooth muscle to cause diarrhea, colic, and malabsorption. (msdmanuals.com)
  • Renal Cell Carcinoma Unclassified with Medullary Phenotype in a Patient with Neurofibromatosis Type 2. (viictr.org)
  • As reported by Medscape Medical News , everolimus previously was approved by the FDA for the treatment of advanced renal cell carcinoma refractory to sunitinib or sorafenib therapy. (medscape.com)
  • The relationship between blood pressure and risk of renal cell carcinoma. (who.int)
  • Epidemiology of Renal Cell Carcinoma: 2022 Update. (who.int)
  • Mycotoxin Exposure and Renal Cell Carcinoma Risk: An Association Study in the EPIC European Cohort. (who.int)
  • Biomarkers of the transsulfuration pathway and risk of renal cell carcinoma in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. (who.int)
  • The final pathologic diagnosis was well-differentiated carcinoid tumor of a malignant nature. (springer.com)
  • The age at diagnosis varies somewhat among specific tumor locations but typically, most people diagnosed with a carcinoid tumor are in their 50s. (medifocus.com)
  • Methods of analysis of tumors of the DNS are also presented because some of these techniques are indispensable for the diagnosis of many neuroendocrine neoplasms. (basicmedicalkey.com)
  • Many broad-spectrum IHC markers are available to aid in the diagnosis of neuroendocrine neoplasms. (basicmedicalkey.com)
  • Primary cervical carcinoid tumor is extremely rare, but should be included in the differential diagnosis of enhancing expansile extradural masses compressing the spinal cord and nerves. (biomedcentral.com)
  • 19 ] Immunohistochemistry and electron microscopy are invaluable techniques for diagnosis and subclassification, but most lung tumors can be classified by light microscopic criteria. (cancer.gov)
  • On July 31, 2013, the Prostate Cancer Foundation assembled a working committee on the molecular biology and pathologic classification of neuroendocrine (NE) differentiation in prostate cancer. (nih.gov)
  • It is unclear if the morphologic pattern and appearance of neuroendocrine differentiation varies based on the type of anti-androgen regimen. (healthyprostateclub.com)
  • Neuroendocrine differentiation has been foundin 50% to 100% of prostate neoplasms of all stages. (cancernetwork.com)
  • Recent studies have focused on neuroendocrine differentiation as a mechanism by which these tumors escape hormonal control [2-4]. (cancernetwork.com)
  • However, the proportion of neuroendocrine differentiation was found to be much higher in follow-up studies and it is now thought that 50% to 100% of all prostate neoplasms (including benign prostatic tissue) contain at least some neuroendocrine cells [3,5]. (cancernetwork.com)
  • In MEN1 patients, special attention should be paid to evaluate the progression duodenopancraetic neuroendocrine tumors because of their malignant potential. (nih.gov)
  • Welcome @tufan , I'm sorry to hear that treatment thus far has not slowed the progression of the neuroendocrine tumor of the lung. (mayoclinic.org)
  • Multiple endocrine neoplasia type 1 is a rare genetic syndrome, characterized by the co-occurrence, in the same individual or in related individuals of the same family, of hyperparathyroidism, duodenopancraetic neuroendocrine tumors, pituitary adenomas, adrenocortical tumors, and neuroendocrine tumors (carcinoids) in the thymus, the bronchi, or the stomach. (nih.gov)
  • Recent studies have shown beyond doubt that the old classification paradigm of "small cell carcinoma vs. non-small cell carcinoma" is now obsolete, and that the correct "subclassification" of lung cancer cases is necessary to assure that patients receive optimum management. (wikipedia.org)
  • High-power photomicrograph of small cell carcinoma on the left side of the image with normal ciliated respiratory epithelium on the right side of the image. (medscape.com)
  • Separate worldwide data for small cell carcinoma are not available. (medscape.com)
  • Approximately 74% of all carcinoid tumors arise from the gastrointestinal (GI) tract and the liver is a common site for metastases [ 1 ]. (biomedcentral.com)
  • Central nervous system involvement is rare and has been reported either as metastases to the brain and spine or primary tumors involving the sacrococcygeal spine. (biomedcentral.com)
  • During the procedure, small plastic particles impregnated with chemotherapy are injected directly into the artery that feeds the tumor(s). (doctorsimaginggroup.com)
  • This treatment results in tumor destruction by eliminating its blood supply and administering high dose chemotherapy adjacent to the cancer cells. (doctorsimaginggroup.com)
  • chemotherapy may be used for malignant tumors. (msdmanuals.com)
  • Although pulmonary carcinoids show relatively good prognosis in comparison to carcinomas, metastatic disease and relapse do occur. (who.int)
  • Symptoms are often associated with the site of tumor origin and reflect the tumor obstructing organs involved in normal body function but may be less specific if related to carcinoid syndrome. (medifocus.com)
  • Malignant Carcinoid Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (harvard.edu)
  • This graph shows the total number of publications written about "Malignant Carcinoid Syndrome" by people in Harvard Catalyst Profiles by year, and whether "Malignant Carcinoid Syndrome" was a major or minor topic of these publication. (harvard.edu)
  • Below are the most recent publications written about "Malignant Carcinoid Syndrome" by people in Profiles. (harvard.edu)
  • Assessment of change in quality of life, carcinoid syndrome symptoms and healthcare resource utilization in patients with carcinoid syndrome. (harvard.edu)
  • Impact of carcinoid syndrome symptoms and long-term use of somatostatin analogs on quality of life in patients with carcinoid syndrome: A survey study. (harvard.edu)
  • Changes in Weight Associated With Telotristat Ethyl in the Treatment of Carcinoid Syndrome. (harvard.edu)
  • Telotristat ethyl in carcinoid syndrome: safety and efficacy in the TELECAST phase 3 trial. (harvard.edu)
  • Understanding the Patient Experience with Carcinoid Syndrome: Exit Interviews from a Randomized, Placebo-controlled Study of Telotristat Ethyl. (harvard.edu)
  • Cost reduction from resolution/improvement of carcinoid syndrome symptoms following treatment with above-standard dose of octreotide LAR. (harvard.edu)
  • Retrospective review of serotonergic medication tolerability in patients with neuroendocrine tumors with biochemically proven carcinoid syndrome. (harvard.edu)
  • 13 Majeed F, Porter TR, Tarantolo S, Duhachek-Stapelman A, Xie F, Elhendy A. Carcinoid crisis and reversible right ventricular dysfunction after embolization in untreated carcinoid syndrome. (thieme-connect.com)
  • Peritonectomy - Removes cancerous tumors from the lining of the abdominal cavity. (ucsd.edu)
  • Rare intestinal carcinoids with only intra-abdominal spread can drain directly into the systemic circulation or the lymphatics and cause symptoms. (msdmanuals.com)
  • 1 The most frequent primary tumor types of anterior mediastinal masses are thymic tumors and lymphoma, with approximate proportions of 35% and 25% among mediastinal lesions, respectively. (allenpress.com)
  • Carcinoid tumors were initially identified in 1888 and were thought to clinically and histologically (cellular appearance under a microscope) resemble carcinoma cells (highly malignant cancer cells) but behave in a more benign fashion than true cancer cells. (medifocus.com)
  • A tumor can spread to other body parts and be cancerous or noncancerous (benign). (ucsd.edu)
  • The availability of an anti-androgen receptor (AR) monoclonal antibody has allowed the identification of both AR-positive and AR-negative neuroendocrine subpopulations in both benign and malignant tumors [5]. (cancernetwork.com)
  • SEGAs are slow-growing, benign brain tumors that occur in up to 20% of patients with tuberous sclerosis , a genetic disorder that affects about 25,000 to 40,000 people in the United States. (medscape.com)
  • The two main types of appendix cancer are called carcinoid tumors and carcinomas. (mskcc.org)
  • Some evidence suggests that cells with the rhabdoid phenotype result from mutations occurring in some of the cells descending from the "parent" tumor, leading to the "emergence" of distinct populations of characteristic cells with the rhabdoid phenotype within the parent neoplasm, often in the peripheral part of the tumor. (wikipedia.org)
  • However, the tumor biopsy revealed a malignant neoplasm that originating from neuroendocrine cells. (biomedcentral.com)
  • However, the pathological finding suggested a malignant neoplasm originating form neuroendocrine cells (Fig. 2A ). (biomedcentral.com)
  • We herein present what we believe is only the 47th reported case of a primary carcinoid tumor occurring in the extrahepatic bile ducts. (springer.com)
  • These lesions are accessible through endoscopic/endobronchial ultrasound-guided or computed tomography-guided fine-needle aspiration cytology and represent a wide range of primary and metastatic tumors. (allenpress.com)
  • Tumors metastatic to mediastinal lymph nodes represent the most common mediastinal lesions and must be differentiated from primary lesions. (allenpress.com)
  • GATA3 expression in primary lung carcinomas: correlation with histopathologic features and TTF-1, napsin A, and p40 expression Wang M, Chen P, Cai G . GATA3 expression in primary lung carcinomas: correlation with histopathologic features and TTF-1, napsin A, and p40 expression. (yale.edu)
  • Primary hepatic carcinoid tumor (PHCT) is very rare and difficult to diagnose before biopsy or operation. (biomedcentral.com)
  • Heterogeneous tumor-immune microenvironments between primary and metastatic carcinoid tumors differentially respond to anti-PD-L1 antibody therapy. (go.jp)
  • Primary Ewing Sarcoma/Primitive Neuroectodermal Tumor of the Kidney: The MD Anderson Cancer Center Experience. (viictr.org)
  • We report the first case of a primary carcinoid tumor of the cervical spine. (biomedcentral.com)
  • We report the first case, to the best of our knowledge, of a primary carcinoid tumor in the cervical spine. (biomedcentral.com)
  • From there, the doctor will use the TNM system, which identifies a primary tumor (T), a tumor that has spread to lymph nodes (N), or cancer that has metastasized (M). (immunitytherapycenter.com)
  • Metabolic products released by primary pulmonary and ovarian carcinoids bypass the portal route and may similarly induce symptoms. (msdmanuals.com)
  • There are several kinds of appendix tumors, some of which are cancerous and some of which are not. (mskcc.org)
  • Carcinoid tumors of the extrahepatic bile duct are exceedingly rare and account for between 0.1% and 2% of all gastrointestinal carcinoid tumors, with most reported cases arising from the gallbladder. (springer.com)
  • Hepatic resection in 485 R0 pT2 and pT3 cases of advanced carcinoma of the gallbladder: results of a Japanese Society of Biliary Surgery survey--a multicenter study. (cancercentrum.se)
  • Should the extrahepatic bile duct be resected or preserved in R0 radical surgery for advanced gallbladder carcinoma? (cancercentrum.se)
  • Indications for pancreatoduodenectomy in patients undergoing lymphadenectomy for advanced gallbladder carcinoma. (cancercentrum.se)
  • Factors influencing recurrence after surgical treatment for T2 gallbladder carcinoma. (cancercentrum.se)
  • About 66% of all carcinoid tumors develop in the gastrointestinal tract. (medifocus.com)
  • The carcinoid tumors are usually located in the gastrointestinal tract and metastasize to the liver. (harvard.edu)
  • However, to communicate effectively with clinicians, the term carcinoid tumor can still be used in parenthesis for neoplasms of the gastrointestinal tract and lungs. (basicmedicalkey.com)
  • The current neuroendocrine classification of cells and tumors uses immunohistochemical (IHC), ultrastructural, and molecular biologic features to define members of the DNS ( 6 , 7 and 8 ). (basicmedicalkey.com)
  • Postoperative histopathologic examination and immunohistochemical analysis were consistent with carcinoid tumor. (biomedcentral.com)
  • Carcinoid tumors share some properties with other cancer cells such as uncontrolled, overproduction of the cells that results in tumor formation and malignant potential. (medifocus.com)
  • Prostate cancer occurs when the cells in the prostate grow abnormally and form a tumor. (cowurine.com)
  • Piperlongumine (PL) inhibits the development of the tumor enzyme to the bulk of prostate cancer cells and helps to prevent its growth. (cowurine.com)
  • Octreoscan (indium in -111 pentetreotide kit) is a diagnostic agent used to locate cancerous tumors. (globalrph.com)