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  • antibody
  • This prospective, multicenter study evaluated the accuracy, safety, and immunogenicity of carcinoembryonic antigen (CEA) antibody imaging in women with known or suspected breast carcinoma. (nih.gov)
  • The ELISA (enzyme-linked immunosorbent assay) is a well-established antibody-based tool for detecting and quantifying antigens of interest. (biocompare.com)
  • He is well known for the discovery of a melanoma-related antigen (later, it is called, Chondroitin Sulfate Proteoglycan-4 (CSPG4)) by producing a monoclonal antibody. (wikipedia.org)
  • human
  • Carcinoembryonic antigen, as measured by radioimmunoassay, is present in two different human colonic tumors that have been serially transplanted and maintained in the cheek pouches of unconditioned, adult golden hamsters. (sciencemag.org)
  • useful
  • Tumor antigens, because of their relative abundance in tumor cells are useful in identifying specific tumor cells. (wikipedia.org)
  • normal
  • This classification, however, is imperfect because many antigens thought to be tumor-specific turned out to be expressed on some normal cells as well. (wikipedia.org)
  • cells
  • Malignant endothelial cells also commonly retain the antigen, so that CD31 immunohistochemistry can also be used to demonstrate both angiomas and angiosarcomas. (wikipedia.org)
  • oncofetal
  • Oncofetal antigens are promising targets for vaccination against several types of cancers. (wikipedia.org)
  • In addition, many of acquired nonself surfaces e.g. carcinoembryonic/oncofetal type neoantigens carrying "internal danger source"/"self turned nonself" type pathogen pattern are also identified and destroyed (e.g. by complement fixation or other cytotoxic attacks) or sequestered (phagocytosed or ensheathed) by the immune system by virtue of the CLRs. (wikipedia.org)