• Their natural substrates are triacylglycerols and under natural conditions they catalyze the hydrolysis of ester bonds at the interface between an insoluble substrate phase and the aqueous phase in which the enzyme is dissolved [ 1 ]. (hindawi.com)
  • Enzymes which catalyze the hydrolysis of carboxylic acid esters with the formation of an alcohol and a carboxylic acid anion. (nih.gov)
  • It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. (expasy.org)
  • The hydrolysis of Sorbitan fatty acid esters occurs within a maximum of 48h for mono-, di- and tri-ester (Croda 1951, Mattson and Nolen 1972, Treon 1967, Wick and Joseph 1953). (europa.eu)
  • Mediates the hydrolysis of steryl esters. (ymdb.ca)
  • This disclosure relates to processes to form arylcyclopropyl carboxylic acids useful in forming molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda. (justia.com)
  • Esters are known to hydrolyse into carboxylic acids and alcohols by esterases (Fukami and Yokoi, 2012). (europa.eu)
  • The resulting fatty acids are either metabolised via the β-oxidation pathway in order to generate energy for the cell or reconstituted into glyceride esters and stored in the fat depots in the body (Berg, 2002). (europa.eu)
  • Fatty acid -- A long chain of aliphatic carboxylic acid (organic, monobasic acids derived from hydrocarbons) found in natural fats and oils, it is also a component of membrane phospholipids and glycolipids. (nih.gov)
  • Lipases (triacylglycerol acylhydrolase, EC 3.1.1.3) are part of the family of hydrolases that act on carboxylic ester bonds. (hindawi.com)
  • The enzyme was also very active toward short chain triglycerides such as triacetin (C2:0) and tributyrin (C4:0), in addition to showing good primary alcohol and organic solvent tolerance, suggesting it could function as an interesting candidate for organic synthesis of short-chain esters such as flavors. (hal.science)
  • An enzyme of the hydrolase class that catalyzes the reaction of triacylglycerol and water to yield diacylglycerol and a fatty acid anion. (wakehealth.edu)
  • Acid lipase -- An enzyme of the hydrolase class produced by glands on the tongue and by the pancreas. (nih.gov)
  • The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These catalytic residues are responsible for the nucleophilic attack on the carbonyl carbon atom of the ester bond. (unl.edu)
  • systematic name carboxylic-ester hydrolase) catalyzes reactions of the following form: a carboxylic ester + H2O ⇌ {\displaystyle \rightleftharpoons } an alcohol + a carboxylate Most enzymes from this group are serine hydrolases belonging to the superfamily of proteins with α/β hydrolase fold. (wikipedia.org)
  • Belongs to the AB hydrolase superfamily. (expasy.org)
  • One of the recombinant enzymes, EstC, showed interesting cold-active esterase activity with a strong potential for the production of valuable esters. (hal.science)
  • Alpha/beta hydrolase domain-containing protein 11 (EC:3. (epigentek.com)
  • All of the substrates were esters composed of the same alcohol moiety, 7-hydroxy-4-methylcoumarin, and acid moieties that structurally mimic some commonly used pyrethroid insecticides, including cypermethrin and cyhalothrin. (nih.gov)
  • These are glycerides consisting of three fatty acid chains covalently bonded to a glycerol molecule through ester linkages. (ymdb.ca)
  • Six proteins such as complement C4-A, immunoglobulin heavy variable 1-2, carboxylic ester hydrolase, fibulin-1, immunoglobulin lambda constant7, secreted phosphoprotein 24 were differentially expressed in individuals with drug resistant HIV as compared to individuals with drug sensitive HIV. (bioinformation.net)
  • In contrast with other alpha/beta hydrolase fold family members, p-nitrobenzyl esterase and acetylcholine esterase have a Glu instead of Asp at the active site carboxylate. (unl.edu)
  • Poly(β-amino esters) prepared from the conjugate addition of bis(secondary amines) or primary amines to a bis(acrylate ester) are described. (patsnap.com)
  • Required for mobilization of steryl ester, thereby playing a central role in lipid metabolism. (ymdb.ca)
  • alpha/beta hydrolase fold. (unl.edu)
  • In absence of a clear indication of selective toxicity towards a specific group of organisms, terrestrial toxicity of Sorbitan esters was tested on the earthworm Eisenia fetida, as recommended by the "Guidance on information requirements and chemical safety assessment Chapter R.7c: Endpoint specific guidance" (ECHA, 2012). (europa.eu)
  • However, since Sorbitan esters are mainly poorly soluble in water and have potential to adsorb to solid soil particles, a soil dwelling organisms, such as the earthworm, which is exposed to the complete soil system via both dermal and oral uptake, is the most relevant test organism to evaluate the terrestrial toxicity of these substances. (europa.eu)