• We previously reported that rats prone to obesity exhibit an exaggerated increase in glucose oxidation and an exaggerated decline in lipid oxidation under a low-fat high-carbohydrate (LF/HC) diet. (frontiersin.org)
  • From these results, we make the hypothesis that in CS rats, CCK increased pancreatic secretion, which may favor a quicker absorption of carbohydrates and consequently induces an enhanced inhibition of lipid oxidation in the liver, leading to a progressive accumulation of fat preferentially in visceral deposits. (frontiersin.org)
  • Hormones produced by adipose tissue play a critical role in the regulation of energy intake, energy expenditure, and lipid and carbohydrate metabolism. (diabetesjournals.org)
  • Adipose tissue plays a crucial role in the regulation of energy homeostasis, insulin sensitivity, and lipid/carbohydrate metabolism. (diabetesjournals.org)
  • Adipocytes produce a number of hormones that have wide-ranging effects on energy intake, energy expenditure, and carbohydrate and lipid metabolism, including nutrient partitioning and fuel selection. (diabetesjournals.org)
  • Determine the effect of diets differing in fat and carbohydrate type on cardiometabolic risk indicators, lipoprotein and fatty acid metabolism, response to lipid modifying therapy, and gene-nutrient interactions, using human, animal and in vitro models. (usda.gov)
  • LAB NAME: Cardiovascular Nutrition In the next 5 years the Cardiovascular Nutrition Laboratory (CNL) will investigate the effects of diets differing in fat type and carbohydrate type on cardiometabolic risk factors, fatty acid metabolism, response to lipid modifying therapy, and gene-nutrient interactions using human, animal and in vitro models. (usda.gov)
  • However, larger, adequately powered, randomized, placebo-controlled, double-blind trials examining multiple measures of carbohydrate and lipid metabolism and insulin homeostasis are needed. (lww.com)
  • Diabetes mellitus (DM) is the metabolic homeostasis disorder regulated by insulin which causes abnormalities in the carbohydrate and lipid metabolism. (wikidoc.org)
  • Regulates carbohydrate and lipid metabolism, and influences protein synthesis. (drugfuture.com)
  • Macronutrients are a class of nutrients that the human body needs in larger amounts in order to function properly and the three main classes of macronutrients include: proteins, carbohydrates, and fats (lipids). (wikipedia.org)
  • We invite researchers working on different compounds (e.g. lipids, (hemi-) cellulose, non-structural carbohydrates) from aquatic (e.g., fish, microbes and seaweed) and terrestrial (e.g., grasses, mosses and trees) origins across all spatiotemporal scales and archives (e.g. herbarium, peat, sediments, loess and tree rings). (copernicus.org)
  • The encoded protein binds specific carbohydrate moieties found on lipids and on the surface of microorganisms. (lsbio.com)
  • Moreover, modulation of the proteins involved in cellular metal homeostasis may help in the regulation of metabolism, adaptability to a diverse range of environmental conditions, and biofortification. (frontiersin.org)
  • Our Formula S/B metabolism booster helps the body process sugar, carbohydrate, fats and proteins, while also supporting the maintenance of bones and good health overall. (herbalmagic.ca)
  • However, the idea of replacing fat with carbohydrate is now challenged by the respective quality of fats and carbohydrates ( 11 ), insisting on the adverse effects of high glycemic index carbohydrate on the control of food intake and on the evolution of insulin resistance ( 12 , 13 ). (frontiersin.org)
  • The great debate exists around protein and not enough attention is paid to carbohydrates and fats. (breakingmuscle.com)
  • That is, it is fewer calories that count, not necessarily the type of calories (eg, carbohydrates or fats). (medscape.com)
  • This can lead to improper hepatic energy homeostasis or even hyperglycaemia, insulin resistance, as well as some symptoms of metabolic syndrome and liver steatosis. (nih.gov)
  • To evaluate the effect of an almond-enriched (high monounsaturated fat, MUFA) or complex carbohydrate-enriched (high carbohydrate) formula-based low-calorie diet (LCD) on anthropometric, body composition and metabolic parameters in a weight reduction program. (greenmedinfo.com)
  • Obtaining most of your carbohydrates near your workout time seems to be most effective in replenishing glycogen stores and more importantly keeping metabolic homeostasis. (breakingmuscle.com)
  • Biotin is a water-soluble vitamin that plays an essential role in maintaining metabolic homeostasis. (herbalmagic.ca)
  • Moreover, HC diets have been proposed as a way to fight against obesity ( 7 - 9 ), and recent dietary guidelines insist on reducing fat intake and maintaining 45-65% of intake as carbohydrate based on whole grain, vegetables, and fruits ( 10 ). (frontiersin.org)
  • Refined grains, a major source of dietary carbohydrates, have been related to impaired glucose homeostasis and obesity. (fabresearch.org)
  • Emerging animal data suggest that in utero exposure to dietary refined carbohydrates may predispose offspring to an obese phenotype, indicating a potential role for nutritional programming in the early origins of obesity, but intergenerational human data are lacking. (fabresearch.org)
  • Almond supplementation of a formula-based LCD is a novel alternative to self-selected complex carbohydrates and has a potential role in reducing the public health implications of obesity. (greenmedinfo.com)
  • In comparing the factors that contribute to the buildup of excess calories in obesity, an imbalance of energy homeostasis can be considered as the basis. (wjgnet.com)
  • Background Recent studies have associated several microRNAs (miRNAs) with childhood obesity and energy homeostasis, suggesting that an individual miRNA profile could be used as an early predictor to estimate the response to weight loss interventions in the design of precision nutrition. (unav.edu)
  • Growing evidence suggests that obesity is a disorder of the energy homeostasis system, [and scientists] need to elucidate the mechanisms underlying this 'upward setting' or 'resetting' of the defended level of body-fat mass," according to a new scientific statement published by the Endocrine Society published June 26 in Endocrine Reviews . (medscape.com)
  • is the largest single obstacle to effective long-term weight loss, we cannot overstate the importance of a coherent understanding of obesity-associated alterations of the energy homeostasis system," Michael W Schwartz, MD, from the University of Washington, Seattle and colleagues stress in the statement. (medscape.com)
  • Therefore, the aim of this meta-analysis was to compare the effect of the Paleolithic diet with other types of diets on glucose and insulin homeostasis in subjects with altered glucose metabolism. (mdpi.com)
  • High-fat (HF) diets, when compared to high-carbohydrate (HC) diets, are more at risk to induce body weight gain because of the large storage capacities of adipose tissue and the low satiating effects of high fat diets, as compared to the low capacities of the glycogen stores and of the de novo lipogenesis cost ( 6 ). (frontiersin.org)
  • This paper provides a narrative review of the role and suggested requirements for digestible carbohydrate in the diets of infants and toddlers. (nature.com)
  • 2021). Low-carbohydrate diets lead to greater weight loss and better glucose homeostasis than exercise. (greatist.com)
  • 2021). The low-carbohydrate diet. (greatist.com)
  • The high-fat diet was purchased from standard diet (SD) consists of 6% fat, 64% carbohydrate and 23% protein, and high-fat diet (HFD) consists of 25% fat, 48% carbohydrate, and 20% protein. (hindawi.com)
  • The portfolio low-carbohydrate diet (PLCD) is a plant-based diet with 40% carbohydrates combined with five cholesterol-lowering foods and nutrients. (biomedcentral.com)
  • On the other hand, the ketogenic diet (KD) is a nutritional protocol with 10% carbohydrates. (biomedcentral.com)
  • The ketogenic diet is a high-fat, low-carbohydrate diet that alters metabolism and is used in the treatment of pediatric epilepsy that does not respond to conventional therapies. (azbigmedia.com)
  • These include small numbers of intake studies, differing approaches to analysing carbohydrate, a variety of terms used to describe sugars intakes and a dearth of information about starch intakes. (nature.com)
  • In infants, minimum carbohydrate (mainly lactose) intake should be 40% of total energy, gradually increasing to 55% energy by the age of 2 years. (nature.com)
  • Carb cycling involves the intentional fluctuation of daily, weekly, or monthly carbohydrate intake. (greatist.com)
  • Carbohydrate intake during exercise can delay the onset of fatigue and improve performance of prolonged exercise as well as exercise of shorter duration and greater intensity (e.g., continuous exercise lasting about 1 h and intermittent high-intensity exercise), but the mechanisms by which performance is improved are different. (gssiweb.org)
  • During prolonged exercise, the performance benefits of carbohydrate ingestion are likely achieved by maintaining or raising plasma glucose concentrations and sustaining high rates of carbohydrate oxidation, whereas during intense exercise, carbohydrate intake seems to positively affect the central nervous system. (gssiweb.org)
  • However, even when carbohydrate is ingested, there is almost always a negative energy balance during exercise, i.e., the energy expenditure exceeds the energy intake. (gssiweb.org)
  • For these reasons, it makes sense to increase carbohydrate intake during exercise and thereby increase carbohydrate oxidation by exercising muscles. (gssiweb.org)
  • This suggests that AstA is regulating the balance between DILP and AKH, believed to be important for the maintenance of nutrient homeostasis in response to changing ratios of dietary sugar and protein. (ruc.dk)
  • When a combination of carbohydrates is ingested (e.g., glucose and fructose) oxidation rates of slightly more than 100 g/h can be achieved if large amounts of carbohydrate are ingested (e.g. (gssiweb.org)
  • In long-duration exercise, a greater contribution of exogenous carbohydrate (carbohydrate ingested in beverages or other foods) will spare liver glycogen, prevent a drop in blood glucose concentration, and help maintain the high rate of carbohydrate oxidation necessary to sustain exercise intensity. (gssiweb.org)
  • Among the peripheral signals that are generated to regulate the uptake of food, signals from adipose tissue are of major relevance and involve the maintenance of energy homeostasis through processes such as lipogenesis, lipolysis, and oxidation of fatty acids. (wjgnet.com)
  • Digestible carbohydrates are one of the main sources of dietary energy in infancy and childhood and are essential for growth and development. (nature.com)
  • Digestible dietary carbohydrates, primarily lactose, are one of the main sources of dietary energy in this crucial period. (nature.com)
  • A review examining the role of these three hormones in regulating energy homeostasis and insulin action was published in early 2002. (diabetesjournals.org)
  • Therefore, athletes must find the appropriate balance between ingesting enough carbohydrate to provide extra energy, but not so much as to increase the risk of gastrointestinal discomfort. (gssiweb.org)
  • We recommend using our Formula S/B metabolism booster if you are or will be consuming more sugar than usual, such as desserts, wine, and carbohydrates, or if you experience hunger and energy crashes throughout the day from blood sugar spikes following carbohydrate-rich meals. (herbalmagic.ca)
  • 18% total fat, 5% MUFA and 53% carbohydrate as percent of dietary energy) featuring equivalent calories and protein. (greenmedinfo.com)
  • Several mechanisms controlling these processes are conserved in Drosophila, where homeostasis and energy mobilization are regulated by the glucagon-related adipokinetic hormone (AKH) and the Drosophila insulin-like peptides (DILPs). (ruc.dk)
  • The primary role of carbohydrates is to supply energy to all cells in the body. (pressbooks.pub)
  • The statement calls for wide-ranging research to better understand "how genetic, developmental, and environmental forces affect the energy homeostasis system. (medscape.com)
  • At the end of the study, body composition was measured in all the rats, and they were classified as carbohydrate resistant (CR) or carbohydrate sensitive (CS) according to their adiposity. (frontiersin.org)
  • It seems that treating male adult rats with finasteride causes changes in the carbohydrate metabolism in the liver of their offspring. (nih.gov)
  • To investigate the effect of simvastatin on glucose homeostasis in streptozotocin induced type 2 diabetic rats. (hindawi.com)
  • These data indicate that simvastatin intervention rats may cause hyperglycemia by impairing the function of islet β cells and have an adverse effect on glucose homeostasis, especially on FPG level. (hindawi.com)
  • This protein plays an essential role in surfactant homeostasis and in the defense against respiratory pathogens. (lsbio.com)
  • Polypeptide hormone produced by pancreatic beta cells that regulates carbohydrate homeostasis. (drugfuture.com)
  • There are few established adverse consequences of high intakes of digestible carbohydrate for young children. (nature.com)
  • OBJECTIVE: Knowledge of the cellular mechanisms involved in homeostasis of human squamous oesophagus in the steady state and following chronic injury is limited. (who.int)
  • As described in more detail later in this paper, carbohydrate ingestion during long-duration exercise lasting 2 h or more nearly always delays the onset of fatigue and improves performance. (gssiweb.org)
  • For exercise of shorter duration, lesser amounts of ingested carbohydrate are required compared to more prolonged exercise. (gssiweb.org)
  • Different subcellular compartments are suggested to be linked through complex retrograde signaling networks to regulate cellular metal homeostasis. (frontiersin.org)
  • Finally, the consequences of excess carbohydrate are reviewed, in each case by providing a summary of the available literature including, where available, the results of published systematic reviews of the issue. (nature.com)
  • Carbohydrate Supplementation During Exercise: Does It Help? (gssiweb.org)
  • RESULTS: LCD supplementation with almonds, in contrast to complex carbohydrates, was associated with greater reductions in weight/BMI (-18 vs -11%), waist circumference (WC) (-14 vs -9%), fat mass (FM) (-30 vs -20%), total body water (-8 vs -1%) and systolic blood pressure (-11 vs 0%), P=0.0001-0.05. (greenmedinfo.com)
  • Furthermore, AstA and Dar-2 are regulated differentially by dietary carbohydrates and protein and AstA-neuronal activity modulates feeding choices between these types of nutrients. (ruc.dk)
  • More recently, some studies [ 5 ] have reported that statin therapy may affect glucose homoeostasis in type 2 diabetes patients. (hindawi.com)
  • As discussed below, the mechanism underlying the beneficial effects of carbohydrate ingestion for exercise that lasts about 1 h and perhaps for intermittent exercise (sometimes lasting longer than 1 h) appears to be different than that for more prolonged continuous exercise and is associated with effects on the central nervous system. (gssiweb.org)
  • 1.2 - Relative effects of simple, refined and unrefined carbohydrate on cardiometabolic risk factors, macrophage cholesterol homeostasis, subcutaneous adipose tissue macrophage infiltration/inflammatory gene expression, and intestinal microbiome. (usda.gov)
  • When the genetic information containing the "blueprint" for these substances is disrupted, cell homeostasis is disrupted, resulting in a wide-range of immediate and/or delayed toxicological effects. (cdc.gov)
  • As with prolonged exercise, there is a potential for gastrointestinal distress if an athlete ingests too much carbohydrate during high-intensity exercise. (gssiweb.org)
  • The diet's affects on brain homeostasis have potential for the treatment of other neurological diseases, as well. (azbigmedia.com)
  • Peppermint ( Mentha × piperita ) leaf, microcrystalline cellulose, vegetable magnesium stearate, and silicon dioxide in a non-⁠GMO vegetable capsule composed of vegetable carbohydrate gum and purified water. (newrootsherbal.com)
  • The amount of carbohydrate an individual athlete should ingest during exercise should be determined by trial and error, and a balance should be struck between increasing carbohydrate availability during exercise and minimizing gastrointestinal distress. (gssiweb.org)
  • Carbohydrate may also be beneficial during more intense continuous exercise lasting about 1 h and during intermittent high-intensity exercise. (gssiweb.org)
  • Carbohydrate from a single source, such as glucose, can only be oxidized at rates of approximately 60 g/h. (gssiweb.org)