Filter...

Chemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesTechnology, Industry, AgricultureInformation Science

Select a category...

Acidic GlycosphingolipidsGlycosphingolipidsSulfoglycosphingolipidsChromatography, Thin LayerCarbohydrate SequenceNeutral GlycosphingolipidsCarbohydratesCarbohydrate MetabolismGangliosidesLactosylceramidesDietary CarbohydratesGlobosidesGlucosylceramidesCerebrosidesGlycolipidsCarbohydrate ConformationG(M3) GangliosideCeramidesSphingolipidsG(M1) Ganglioside

GSLsLipidSialic acidReceptorsStomachDetectionStructuresCellSpecificGangliosidesCharacterizationSialicCeramideDegradationLiverAntigenAnalysisHumanAnimalsGroupsSite

GSLs2

• These glycosphingolipids (GSLs) were expressed in all cell lines with concentrations ranging from 210 to 330 ng per 2 × 10 6 cells. (karger.com)
• Glycosphingolipids (GSLs) are a subclass of glycolipids that are found in cell membranes of various organisms ranging from bacteria to humans. (springer.com)

Lipid2

• To characterize biomarkers in neural tumors, we analyzed the acidic lipid fractions of 13 neural tumor cell lines using enzyme-linked immunoabsorbent assay (ELISA) and high-performance thin-layer chromatography (HPTLC) immunostaining. (karger.com)
• Although lipids are a distinct class of biomolecules, we shall see that they often occur combined, either covalently or through weak bonds, with members of other classes of bio-molecules to yield hybrid molecules such as glycolipids , which contain both carbohydrate and lipid groups, "and lipoproteins , which contain both lipids and proteins. (medmuv.com)

Sialic acid1

• Bullfrog sialic acid-binding lectin (cSBL) is a multifunctional protein that has carbohydrate-binding and ribonuclease activities. (bvsalud.org)

Receptors1

• Gb 3 glycosphingolipids are the specific receptors for bacterial Shiga toxin. (springer.com)

Stomach2

• This is because the enzyme is not present in the human stomach, as the optimal pH is 5.6, while the pH of a human's stomach is acidic (between 1.5 and 3.5). (wikipedia.org)
• During the digestive process of the bonnethead shark, the acidic stomach weakens the cell walls of the seagrass and allows for β-glucosidase to enter the cell and digest the cellulose. (wikipedia.org)

Detection2

• As a leading resource provider in the glycobiology field, CD BioGlyco has various systematic services for the synthesis, modification, analysis, and activity detection of carbohydrate-based anticoagulant glycomedicine. (bioglyco.com)
• Valmu L , Kalkkinen N, Husa A and Rye P D (2005) Differential susceptibility of transferrin glycoforms to chymotrypsin: a potential approach to the detection of carbohydrate deficient transferrin. (leenavalmu.fi)

Structures1

• Furthermore, we observed that SAL promoted the formation of lysosome-like structures, which are LAMP1 positive but not acidic in HeLa cells, which can trap sunitinib. (bvsalud.org)

Cell2

• Sulfated glucuronosyl glycosphingolipids (SGGLs) are cell surface molecules that are endowed with the Human Natural Killer-1 (HNK-1) carbohydrate epitope. (karger.com)
• Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes. (embl-heidelberg.de)

Specific1

• Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories. (lookformedical.com)

Gangliosides7

• 1] Gangliosides are more complex glycosphingolipids in which oligosaccharide chains containing N-acetylneuraminic acid (NeuNAc) are attached to a ceramide. (afcdb.ca)
• NeuNAc, an acetylated derivative of the carbohydrate sialic acid, makes the head groups of Gangliosides anionic. (afcdb.ca)
• Gangliosides are glycosphingolipids. (afcdb.ca)
• Deficiencies in lysosomal enzymes that degrade the carbohydrate portions of various gangliosides are responsible for a number of lysosomal storage diseases such as Tay-Sachs disease, Sandhoff disease, and GM1 gangliosidosis. (afcdb.ca)
• Yet, what roles do carbohydrates on gangliosides play in this process remains unknown. (bvsalud.org)
• Gangliosides are important glycosphingolipids involved in a multitude of physiological functions. (bvsalud.org)
• 13. Neutral glycosphingolipids and gangliosides of bovine thyroid. (nih.gov)

Characterization9

• Isolation and characterization of the major glycosphingolipids from the liver of the rainbow trout (Oncorhynchus mykiss): identification of an abundant source of 9-O-acetyl GD3. (nih.gov)
• 1. Characterization of Human Medullary Thyroid Carcinoma Glycosphingolipids Identifies Potential Cancer Markers. (nih.gov)
• 2. Characterization of novel nonacid glycosphingolipids as biomarkers of human gastric adenocarcinoma. (nih.gov)
• 3. Characterization of Glycosphingolipids in the Human Parathyroid and Thyroid Glands. (nih.gov)
• 4. Characterization of moose intestinal glycosphingolipids. (nih.gov)
• 5. Characterization of sheep erythrocyte glycosphingolipids recognized by human anti-Forssman antibodies. (nih.gov)
• 7. Characterization of glycosphingolipids from gastrointestinal stromal tumours. (nih.gov)
• 12. Isolation and structural characterization of glycosphingolipids of in vitro propagated bovine aortic endothelial cells. (nih.gov)
• 19. Isolation and characterization of the major acidic glycosphingolipids from the liver of the English sole (Parophrys vetulus). (nih.gov)

Sialic3

• Ganglioside is a compound composed of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acids (AKA n-acetylneuraminic acid, NANA) linked on the sugar chain. (afcdb.ca)
• Wikipedia] Particularly, Ganglioside GT1b (d18:1/16:0) is a GT1b ganglioside, A glycosphingolipid (ceramide and oligosaccharide) or oligoglycosylceramide with one or more sialic acids (i.e. n-acetylneuraminic acid) linked on the sugar chain. (afcdb.ca)
• These are lipid molecules composed of a glycosphingolipid (ceramide and saccharide) with one or more sialic acids linked on the sugar chain. (afcdb.ca)

Ceramide1

• The numbered subscripts 1, 2 and 3 refer to the carbohydrate sequence that is attached to the ceramide. (afcdb.ca)

Degradation3

• However, humans do require β-glucosidase, Lysosomal β-glucosidase, as it plays an important role in the degradation of glycosphingolipids. (wikipedia.org)
• Glycoprotein degradation, on the other hand, requires many hydrolases to act on carbohydrates and involves intracellular transport of both glycosidases and their substrate glycoproteins. (intechopen.com)
• Collectively, enzymes that modulate glycoprotein carbohydrates during their biosynthesis and degradation are called glycoenzymes, which play critical roles in maintaining cellular structure and function. (intechopen.com)

Liver1

• The carbohydrate structures of the major glycosphingolipids from the liver of the rainbow trout Oncorhynchus mykiss have been examined. (nih.gov)

Antigen1

• 8. Aberrant expression of tumor-associated carbohydrate antigen Globo H in thyroid carcinoma. (nih.gov)

Analysis1

• 17. Analysis of glycosphingolipids of human head and neck carcinomas with comparison to normal tissue. (nih.gov)

Human1

• 9. Comparison of the glycosphingolipids of human-induced pluripotent stem cells and human embryonic stem cells. (nih.gov)

Animals1

• An extensive review of these glycosphingolipids found in bacteria, fungi, plants, and animals was written by Tan RX et al. (gerli.com)

Groups1

• The separation of glycosphingolipids into groups and subgroups is made according to the structure of the carbohydrate moiety but they show also great variations in the acyl moiety as well as in the sphingosine moiety. (gerli.com)

Site1

• The carbohydrate portion of the ganglioside GM1 is the site of attachment of cholera toxin, the protein secreted by Vibrio cholerae. (afcdb.ca)