• citation needed] In molecular biology, carbenicillin may be preferred as a selecting agent (see plasmid stabilisation technology) because its breakdown results in byproducts with a lower toxicity than analogous antibiotics like ampicillin. (wikipedia.org)
  • Octenidine/carbenicillin also exhibited bioequivalence to azithromycin and doxycycline , two currently prescribed antibiotics. (allergy-link.com)
  • Carbenicillin Disodium Salt is a penicillin-derived β-lactam antibiotic that interferes with cell wall synthesis, primarily in gram-negative bacteria such as Pseudomonas aeruginosa , while showing low toxicity to plant tissues. (agscientific.com)
  • Carbenicillin Disodium Salt is a semi-synthetic penicillin antibiotic with a relatively greater spectrum of activity against Gram-negative bacteria. (canvaxbiotech.com)
  • Carbenicillin is a bactericidal antibiotic belonging to the carboxypenicillin subgroup of the penicillins. (wikipedia.org)
  • Whereas efflux pumps such as MexAB-OprM have been thought to predominate, here we show that a novel ATP Binding Cassette (ABC) transporter that mediates influx of carbenicillin from the periplasm to the cytoplasm and away from its cell wall target plays an important role in the resistance of P. aeruginosa to this antibiotic. (allergy-link.com)
  • A strategy involving the electrostatic interacti on between a common antiseptic and a discontinued antibiotic (i.e. octenidine and carbenicillin) was evaluated as a potential treatment for gonorrhoea. (allergy-link.com)
  • AGL-1 also has rifampicin and carbenicillin resistance genes in the genome useful for selection. (goldbio.com)
  • Docking and pharmacological analyses showed that verapamil and carbenicillin compete for the same site on the PA1113 gene protein, explaining the inhibitory effect of verapamil on carbenicillin uptake, and furthermore suggest that the PA1113 ABC transporter accounts for about 30% of P. aeruginosa carbenicillin resistance. (allergy-link.com)
  • Our findings demonstrate that the PA1113 gene product helps mediate carbenicillin resistance by transporting it away from its cell wall target and represents a promising new therapeutic target. (allergy-link.com)
  • Using amino acid sequence homology with known verapamil protein targets as a probe, we determined that the PA1113 gene product, an ABC transporter, mediates carbenicillin uptake into the bacterial cytoplasm. (allergy-link.com)
  • Antibacterial activities for octenidine dihydrochloride, disodium carbenicillin, octenidine/carbenicillin and stoichiometrically equivalent 1:1 octenidine dihydrochloride to disodium carbenicillin were assessed using the Kirby-Bauer disc diffusion assay for N. gonorrhoeae (ATCC 49226) and three clinical isolates. (allergy-link.com)
  • Likewise, octenidine/carbenicillin had improved predicted permeability compared with octenidine dihydrochloride. (allergy-link.com)
  • Each mL contains the equivalent of 150 mg clindamycin, 0.5 mg disodium edetate and 9.45 mg benzyl alcohol added as preservative in each mL. (nih.gov)
  • Carbenicillin at high doses can cause bleeding. (wikipedia.org)
  • SERS investigation and high sensitive detection of carbenicillin disodium drug on the Ag substrate. (allergy-link.com)
  • While both MexXY-OprA and MexXY-OprM complexes are capable of effluxing aminoglycosides, the bi-anionic β-lactam molecules carbenicillin and sulbenicillin were found to only be the substrate of MexXY-OprA. (allergy-link.com)
  • Additive in vitro antibacterial activities against N. gonorrhoeae were observed in this study, which suggests octenidine/carbenicillin could be a useful agent in reducing N. gonorrhoeae transmission and minimizing gonorrhoea infections. (allergy-link.com)
  • Carbenicillin is also more stable at lower pH than ampicillin. (wikipedia.org)
  • citation needed] In molecular biology, carbenicillin may be preferred as a selecting agent (see plasmid stabilisation technology) because its breakdown results in byproducts with a lower toxicity than analogous antibiotics like ampicillin. (wikipedia.org)
  • Carbenicillin is more stable than ampicillin and results in fewer satellite colonies on selection plates. (wikipedia.org)
  • During tests, the researchers used four antibiotics - ceftriaxone sodium, cefotaxime sodium, carbenicillin disodium and ampicillin sodium - to demonstrate the PDA/PEI-coated membrane's electro-driven filtration performance. (materialstoday.com)
  • The solutions contain 20% (200 mg/mL) or 10% (100 mg/mL) acetylcysteine, with disodium edetate in purified water. (nih.gov)
  • This product contains the following inactive ingredients: disodium edetate, sodium hydroxide, purified water, and hydrochloric acid, if necessary. (nih.gov)
  • Each mL contains the equivalent of 150 mg clindamycin, 0.5 mg disodium edetate and 9.45 mg benzyl alcohol added as preservative in each mL. (nih.gov)
  • Disodium edetate has been added at a concentration of 0.04 mg/mL. (nih.gov)
  • Carbenicillin disodium salt is a penicillin-derived β-lactam antibiotic, which inhibits the synthesis of peptidoglycan, a key component of the bacterial cell wall, and is most effective against gram-negative bacteria but may also have some effect against gram-positive bacteria. (yeasenbiotech.com)
  • Carbenicillin is a bactericidal antibiotic belonging to the carboxypenicillin subgroup of the penicillins. (wikipedia.org)
  • Limited information indicates that carbenicillin produces low levels in milk that are not expected to cause adverse effects in breastfed infants. (nih.gov)
  • After a single 1 gram intramuscular dose of carbenicillin in 3 women, milk levels averaged between 0.1 and 0.24 mg/L over the first 6 hours after the dose. (nih.gov)
  • Carbenicillin Disodium, USP Susceptibility and Minimum Inhibitory Concentration (MIC) Data" (PDF). (wikipedia.org)
  • Use of carbenicillin can cause hypokalemia by promoting potassium loss at the distal convoluted tubule of the kidney. (wikipedia.org)