Loading...
  • inhibits
  • Dipyridamole inhibits the phosphodiesterase enzymes that normally break down cAMP (increasing cellular cAMP levels and blocking the platelet aggregation response to ADP) and/or cGMP. (wikipedia.org)
  • Dipyridamole is used to dilate blood vessels in people with peripheral arterial disease and coronary artery disease Dipyridamole has been shown to lower pulmonary hypertension without significant drop of systemic blood pressure It inhibits formation of pro-inflammatory cytokines (MCP-1, MMP-9) in vitro and results in reduction of hsCRP in patients. (wikipedia.org)
  • Stroke
  • A combination of dipyridamole and aspirin (acetylsalicylic acid/dipyridamole) is FDA-approved for the secondary prevention of stroke and has a bleeding risk equal to that of aspirin use alone. (wikipedia.org)
  • However, it is not licensed as monotherapy for stroke prophylaxis, although a Cochrane Review suggested that dipyridamole may reduce the risk of further vascular events in patients presenting after cerebral ischemia. (wikipedia.org)
  • Uses
  • Dipyridamole also has non-medicinal uses in a laboratory context, such as the inhibition of cardiovirus growth in cell culture. (wikipedia.org)