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  • viruses
  • Self-assembly of viruses seems to obey the principles of thermodynamically reversible self-assembly but assembled shells ('capsids') strongly resist disassembly. (asknature.org)
  • subunit
  • dsRNA mycovirus capsids are based on a 120-subunit T = 1 capsid, with a dimer as the asymmetric unit. (mdpi.com)
  • In re-organizing into the mature capsid lattice, each subunit of the precursor lattice must change its conformation, or its relationship with its neighbours, or both. (hindawi.com)
  • cytoplasm
  • After endocytosis into the host cell, peptide gamma is probably exposed in endosomes, where it permeabilizes the endosomal membrane, facilitating translocation of viral capsid or RNA into the cytoplasm (By similarity). (uniprot.org)
  • lipid
  • Enteroviruses belong to a large family of picornaviridae, which are about 30- to 35-nm icosahedral bionanoparticles consisting of a protein capsid without a lipid envelope ( 1 ). (pnas.org)
  • hexamers
  • It is similar to the stochastic model of fullerene growth, but takes into account variations in the composition of pentamers and hexamers that are responsible for the final capsid size. (hindawi.com)
  • Capsid protein that self-associates to form 11 pentons, building the T=13 laevo capsid in association with 160 hexamers of gp23* and one dodecamer of gp20. (uniprot.org)
  • assembly
  • Here, we examine that question with respect to viral capsid assembly by studying the 'pathway complexity' of model capsid assembly systems, which we informally define as the number of reaction pathways and intermediates one must consider to accurately describe a given system. (hindawi.com)
  • The models provide complementary information in support of a common conclusion that the ability of simple pathway models to adequately explain capsid assembly kinetics varies considerably across the space of biologically meaningful assembly parameters. (hindawi.com)
  • Assembly of herpes simplex virus type 1 capsids using a panel of recombinant baculoviruses. (semanticscholar.org)
  • Virus
  • Synthetic peptide corresponding to C terminal residues of Drosophila C virus DCV capsid polyprotein. (abcam.com)
  • The atomic structure of the T = 1 capsids of four mycoviruses was resolved: the L-A virus of Saccharomyces cerevisiae (ScV-L-A), Penicillium chrysogenum virus (PcV), Penicillium stoloniferum virus F (PsV-F), and Rosellinia necatrix quadrivirus 1 (RnQV1). (mdpi.com)
  • stochastic
  • We use two model types for this study: ordinary differential equation models, which allow us to precisely and deterministically compare the accuracy of capsid models under different degrees of simplification, and stochastic discrete event simulations, which allow us to sample use of reaction intermediates across a wide parameter space allowing for an extremely large number of possible reaction pathways. (hindawi.com)
  • Stability
  • These resilient proteinaceous packets self-assemble in response to a variety of weak forces that, in concert, provide the capsid with a great deal of stability. (asknature.org)
  • Target
  • The capsid has become an attractive target for the development of new antiretroviral drugs. (nsf.gov)