• Adhesion experiment in vitro was performed with mouse microvascular endothelial cells (bEnd.3) and the ratio of the number of UCA to that of cells at the same field was compared. (thno.org)
  • i.p) or vehicle administered 24 hours after permanent middle cerebral artery occlusion (pMCAO) on behavior, angiogenesis, ultra-structural integrity of brain capillary endothelial cells, and expression of EPO and VEGF were assessed. (researchgate.net)
  • These results suggested that catalpol might contribute to infarcted-brain angiogenesis and ameliorate the edema of brain capillary endothelial cells (BCECs) by upregulating VEGF and EPO coordinately. (researchgate.net)
  • Mechanistic and functional investigations were carried out in human umbilical vein endothelial cells and a newly established mouse model. (bmj.com)
  • Background: Alveolar capillary dysplasia (ACD) is a rare cause of severe pulmonary hypertension and respiratory failure in neonates. (researchgate.net)
  • PAH is characterized by progressive, obliterative remodeling of pulmonary arterioles, pre-capillary vessel loss, right heart failure and death. (nature.com)
  • In contrast to later postnatal development in mammals, the pulmonary BGB in chick develops primarily in ovo prior to hatching and is characterized by a massive increase in air and blood capillaries, which develop with a progressive reduction of the lung interstitium [ 8 , 9 ]. (biomedcentral.com)
  • CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. (thermofisher.com)
  • Tumor angiogenesis was determined by CD31 immunohistochemistry. (biomedcentral.com)
  • In vivo mouse xenograft model was used to evaluate the growth-promoting and angiogenesis-enhancing effects of exosome-treated adipocytes. (biomedcentral.com)
  • The tumor exosome-treated adipocytes, named exo-adipocytes, promoted tumor growth, enhanced angiogenesis, and recruited more macrophages in mouse xenograft model. (biomedcentral.com)
  • Interestingly, intra-nervous blood vessel density significantly decreases during post-natal period, starting from P10. (elifesciences.org)
  • BBB-impermeable fluorescent tracer injected transcardially to mice is selectively uptaken by DG NSCs within a minute, via the vessel-associated apical processes. (elifesciences.org)
  • Therefore, PBMT might ameliorate whole-body insulin resistance in diabetic mice. (google.com)
  • Using mouse genetic models, the authors show that Schwann cells regulate vascularization of the sciatic nerve and are required for a decrease in vascular density postnatally. (elifesciences.org)
  • Compared with wild-type littermates, mice overexpressing the GJA4 mutation developed ECH-like pathological morphological characteristics (dilated venous lumen and elevated vascular density) in the retinal superficial vascular plexus at the postnatal 3 weeks, which were reversed by an SGK1 inhibitor, EMD638683. (bmj.com)
  • Later, as alveolarization progresses, secondary septa develop and the microvascular network matures from a double to a single capillary network [ 2 , 5 , 6 ]. (biomedcentral.com)
  • Description: The WM59 monoclonal antibody reacts with human CD31, also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1) and gpIIa. (thermofisher.com)
  • Homotypic interaction of CD31 is important in adhesion, cell-cell and cell-matrix interaction, and signal transduction. (thermofisher.com)
  • CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. (thermofisher.com)
  • D) A 3-dimensional reconstruction of (A). CD31: an endothelial marker, also known as anti-platelet/endothelial cell adhesion molecule-1 (PECAM). (pancreapedia.org)
  • Effects of genipin on HCC were assessed in a patient-derived xenograft nude mice model. (biomedcentral.com)
  • In addition, the therapeutic effects of genipin in a patient-derived HCC xenograft nude mice model were also demonstrated. (biomedcentral.com)
  • The most efficient method to expand limbal stem cells (LSCs) in vitro for clinical transplantation is to culture single LSCs directly on growth-arrested mouse fibroblast 3T3 cells. (drcremers.com)
  • The best densities had been found in cortical, amygdaloid and hippocampal areas. (agckinase.com)
  • Implantation of mock-transduced CS resulted in significant improvement of limb perfusion, increased capillary density and necrosis reduction at 2 weeks post-surgery compared to untreated animals. (biomedcentral.com)
  • Open up in another window Amount 1 The positioning of different diagnostic strategies/tests with regards to morbidity, parasite prevalence, densities, and various levels towards malaria reduction.Picture credit: Fusin Creativa. (tam-receptor.com)
  • Peptidyl arginine deiminase 4 (PAD4), an essential enzyme for neutrophil extracellular trap formation, is overexpressed with adenoviruses in the cortex of mice 1 day before TBI. (biomedcentral.com)
  • Of interest was the obtaining the greatest density while in the cortex was in the major olfactory cortex, located across the amygdala and hippocampus, whilst the significance of this especially massive density inside Docetaxel Taxotere this area is, at current, unknown. (agckinase.com)
  • Photobiomodulation reduces abdominal adipose tissue inflammatory infiltrate of diet-induced obese and hyperglycemic mice. (google.com)
  • Recruitment of CD11b + CD11c + myelomonocytic cells to the metastatic site was also found after whole thorax irradiation at a dose of 15 Gy of mice that significantly enhanced seeding and metastatic growth of intravenously injected cancer cells. (biomedcentral.com)
  • The SUVR of 18 F-BCPP-EF was significantly lower and that of 11 C-PiB was higher in the 15-week-old SAMP10 mice than in the control and 5-week-old SAMP10 mice. (biomedcentral.com)
  • We further highlight the necessity of thorough genetic testing and histopathological examination and propose immunostaining for CD31 and CD34 to facilitate the diagnostic process for better management of infants with ACD. (researchgate.net)
  • Administration of anti-inflammatory M2 macrophages suppresses progression of angiotensin II-induced aortic aneurysm in mice. (nagoya-u.ac.jp)
  • SD-36, which could suppress lymphoma cell growth and inhibit tumor progression in a mice model. (biomedcentral.com)
  • B7H6-particular BiTE therapy improved the success of lymphoma bearing mice and reduced tumor burden SF3a60 of melanoma and ovarian tumor bearing mice. (colinsbraincancer.com)
  • Mouse T cell lymphoma range RMA, melanoma cell range B16F10, and ovarian tumor cell line Identification8 have already been referred to previously (17C19). (colinsbraincancer.com)
  • Mouse T cell lymphoma range RMA/B7H6, melanoma cell range B16F10/B7H6, ovarian tumor cell line Identification8/B7H6 were produced by retrovirus transduction of their parental range RMA, B16F10, or Identification8 cells, respectively, using dualtropic retroviral vectors including the human being gene relating to protocols previously referred to (17). (colinsbraincancer.com)
  • In this work we report on therapeutic efficacy of CS from mouse ADSC transduced to express human vascular endothelial growth factor 165 a/a isoform (VEGF165), which showed potency to restore perfusion and protect tissue in a model of limb ischemia. (biomedcentral.com)
  • A) Whole-mount image of wild-type mouse pancreatic tissue demonstrating the hypervascular microcapillary network of the islet with glucagon in the periphery of the islet. (pancreapedia.org)
  • their size is similar with an upper diameter of 500-700 um in both mice and humans (8). (pancreapedia.org)
  • The present results provide in vivo evidence of a decrease in mitochondrial energy production and elevated amyloidosis at an early stage in SAMP10 mice. (biomedcentral.com)
  • This focus on mouse is due to difficulty in procuring human pancreas. (pancreapedia.org)
  • To become functional, blood vessels mature and specialize by recruitment of mural cells and form a network of arteries, capillaries, and veins. (elifesciences.org)
  • Pancreatic islets are highly vascularized micro-organs with a capillary network that is five to ten times denser than that of the exocrine pancreas ( Figure 1 ) (10). (pancreapedia.org)
  • Our previous studies have demonstrated that sclerostin antibody (Scl-Ab) treatment improves phosphate homeostasis, and increases long bone mass, strength, and mineralization in the Hyp mouse model of XLH. (bvsalud.org)
  • Nuclear positioning, germinal vesicle breakdown, spindle migration, spindle rotation, chromosome segregation, and polar body extrusion are the most critical cellular processes during oocyte meiosis I and II, and a growing number of studies primarily using the mouse oocyte model revealed that actin filaments were critical for these processes, especially for spindle migration. (bioone.org)
  • However, many of these findings have been extrapolated from mice, which remains the most studied animal model in pancreas research. (pancreapedia.org)
  • Here, we used positron emission tomography (PET) to examine the direct relationship between mitochondrial activity ( 18 F-BCPP-EF) and β-amyloid (Aβ) deposition ( 11 C-PiB) in the same brains of senescence-accelerated mouse prone 10 (SAMP10) mice, an Aβ-developing neuroinflammatory animal model showing accelerated senescence with deterioration in cognitive functioning similar to that in MCI. (biomedcentral.com)
  • Children who received transplants showed improved growth rates and started to synthesize intact bone. (stemcellslab.net)
  • The condition is refractory to all available therapies as it irreversibly affects development of the capillary bed in the lungs. (researchgate.net)
  • Lung development timeline and type IV collagen expression in the chicken and the mouse. (biomedcentral.com)
  • a Mouse and chicken lung development comparative timeline. (biomedcentral.com)
  • Most patients with HNC, treated with curative intent, receive a total dose between 50 and 70 gray (Gy), where the dose is parceled into fractions, usually 2 Gy daily, five days a week over a five to seven week period [ 5 ]. (biomedcentral.com)
  • Placental tissues and umbilical cord blood were obtained from healthy newborns after receiving signed informed consents from their mothers. (hindawi.com)
  • CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. (thermofisher.com)
  • 10 6 MDA-MB-468 cells were inoculated into the left fourth mammary gland fat pad in athymic nude-foxn1 mice. (biomedcentral.com)
  • Mouse ADSC (mADSC) isolated from C57 male mice were expanded for CS formation (10 6 cells per CS). (biomedcentral.com)
  • Using mouse models, we discovered that mutations in murine Col4a1 and Col4a2 genes affected the balance between lung epithelial progenitors and differentiated cells. (biomedcentral.com)
  • A Cre-inducible fluorescent reporter line was used to empirically establish the utility of a mouse line expressing Cre Recombinase driven by the Tie2-Promoter, for targeting VE cells. (biomedcentral.com)
  • The current results indicated that PBMT inhibited FFA generation and release in insulin-resistant adipocytes and reduced plasma FFA levels in diabetic db/db mice and HFD-fed mice. (google.com)
  • The immunohistochemical analysis demonstrated temporal upregulation of ATPB levels at 15-week-old, but decreased at 25 week-old SAMP10 mice. (biomedcentral.com)
  • Material and Strategies Mice C57BL/6 mice had been purchased through the National Cancers Institute (Frederick, MD). Mice had been used in test at age 6C12 weeks outdated. (colinsbraincancer.com)
  • The administration of MSG in rats and mice during the first days after birth causes lesions in the arcuate nucleus and median eminence of the hypothalamus,14 and 15 altering the normal functioning of the hypothalamus-hypophysis axis. (c-metinhibitors.com)
  • Registered users receive a variety of benefits including the ability to customize email alerts, create favorite journals list, and save searches. (bioone.org)
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