TNF-Related Apoptosis-Inducing LigandApoptosis Regulatory ProteinsApoptosisLigandsCaspasesCaspase 3Inhibitor of Apoptosis ProteinsProto-Oncogene Proteins c-bcl-2Fas Ligand ProteinDNA FragmentationIn Situ Nick-End LabelingCell Line, Tumorbcl-2-Associated X ProteinSignal TransductionX-Linked Inhibitor of Apoptosis ProteinCell SurvivalCASP8 and FADD-Like Apoptosis Regulating ProteinApoptosis Inducing FactorCells, CulturedCaspase 9Caspase InhibitorsTumor Necrosis Factor-alphaCaspase 8Enzyme ActivationTumor Cells, CulturedMitochondriaTumor Suppressor Protein p53Cell LineCytochromes cbcl-X ProteinCell ProliferationBlotting, WesternFlow CytometryAnnexin A5Amino Acid Chloromethyl KetonesProto-Oncogene ProteinsCysteine Proteinase InhibitorsMembrane GlycoproteinsTransfectionAntineoplastic AgentsCell CycleReceptors, Tumor Necrosis FactorPoly(ADP-ribose) PolymerasesJurkat CellsEnzyme InhibitorsCell DivisionDose-Response Relationship, DrugMice, Inbred C57BLRNA, MessengerDown-RegulationReactive Oxygen SpeciesCD40 LigandRNA, Small InterferingNF-kappa BPhosphorylationCell DeathHL-60 CellsUp-RegulationProtein BindingCaspase 7Time FactorsMembrane Potential, MitochondrialMice, KnockoutReverse Transcriptase Polymerase Chain ReactionGenes, bcl-2Molecular Sequence DataCarrier ProteinsNecrosisCytochrome c GroupReceptors, TNF-Related Apoptosis-Inducing Ligandbcl-2 Homologous Antagonist-Killer ProteinGene Expression RegulationMembrane ProteinsProto-Oncogene Proteins c-aktBH3 Interacting Domain Death Agonist ProteinMyeloid Cell Leukemia Sequence 1 ProteinDNA DamageGene Expression Regulation, NeoplasticImmunohistochemistryStaurosporineDrug SynergismReceptors, Tumor Necrosis Factor, Type IRecombinant ProteinsHeLa CellsGene ExpressionAmino Acid SequenceProtein-Serine-Threonine KinasesCeramidesbcl-Associated Death ProteinFas-Associated Death Domain ProteinNeoplasm ProteinsAntineoplastic Agents, PhytogenicMitogen-Activated Protein KinasesModels, BiologicalMutationOxidative StressProteinsRNA InterferenceDNA-Binding ProteinsEpithelial Cells