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  • tumor
  • Treatment for gastroesophageal junction adenocarcinoma typically involves surgery if the tumor is resectable (able to be removed). (medicinenet.com)
  • Cancer of unknown primary origin (CUP, "occult cancer") is a cancer that is determined to be at the metastatic stage at the time of diagnosis, but a primary tumor cannot be identified. (wikipedia.org)
  • Most cancers typically present as a single primary tumor. (wikipedia.org)
  • For instance, a woman in whom there is axillary lymphadenopathy (swelling in the lymph nodes of the armpit) it is likely that the cancer originated in the breast, and men with lymph node deposits in the mediastinum of the chest and/or retroperitoneal space of the abdomen may have a germ cell tumor. (wikipedia.org)
  • It is generally accepted that cancer of unknown primary site exists because the primary tumor is not identified due to clinical or technological inefficiencies, or because the primary tumor regresses or stays dormant after spreading the cancer cells that generate the metastases. (wikipedia.org)
  • medical citation needed] Because stem cells have a natural ability to migrate and also play a key role in cancer development, it has been proposed that a cancer of unknown primary site may form when deregulated, premalignant or cancerous stem cells migrate away from their natural tissue and give rise to a cancer in the new site before or without generating a tumor in their original tissue. (wikipedia.org)
  • Stem cells can migrate from their natural tissue and initiate a cancer in the new site before generating a detectable tumor in their natural tissue. (wikipedia.org)
  • plural adenocarcinomas or adenocarcinomata /ˌædɪnoʊkɑːrsɪˈnoʊmɪtə/) is a type of cancerous tumor that can occur in several parts of the body. (wikipedia.org)
  • By staining the cells from a biopsy, a pathologist can determine whether the tumor is an adenocarcinoma or some other type of cancer. (wikipedia.org)
  • One study suggests that when signet-ring cells are found in a breast tumor, the presence of gastric cancer should also be considered. (wikipedia.org)
  • In advanced gastric cancers, the prognosis for patients with the SRCCs was significantly worse than for the other histological types, which can be explained by the finding that advanced SRCC gastric cancers have a larger tumor size, more lymph node metastasis, a deeper invasive depth and more Borrmann type 4 lesions than other types. (wikipedia.org)
  • symptoms
  • Common symptoms and signs of gastroesophageal adenocarcinoma include difficulty or pain with swallowing and unintentional weight loss . (medicinenet.com)
  • Throat cancer usually begins with symptoms that seem harmless enough, like an enlarged lymph node on the outside of the neck, a sore throat or a hoarse sounding voice. (wikipedia.org)
  • Signs and symptoms of the most common form of pancreatic cancer may include yellow skin, abdominal or back pain, unexplained weight loss, light-colored stools, dark urine and loss of appetite. (wikipedia.org)
  • Cancer of unknown primary source is not a single type of cancer, although researchers have attempted to find a common characteristic that explains why a cancer might spread very early without causing symptoms at the site of origin. (wikipedia.org)
  • globally
  • In 2015 head and neck cancers globally affected more than 5.5 million people (mouth 2.4 million, throat 1.7 million, larynx 1.4 million) and resulted in more than 379,000 deaths (mouth 146,000, throat 127,400, larynx 105,900). (wikipedia.org)
  • tobacco
  • About 75% of head and neck cancer is due to the use of alcohol or tobacco. (wikipedia.org)
  • Cancers of the mouth are strongly associated with tobacco use, especially use of chewing tobacco or "dip", as well as heavy alcohol use. (wikipedia.org)
  • Risk factors for pancreatic cancer include tobacco smoking, obesity, diabetes, and certain rare genetic conditions. (wikipedia.org)
  • males
  • Soon after that, the vaccine was approved by the FDA for use in males aged 9 to 26 for prevention of genital warts and anal cancer. (wikipedia.org)
  • The panel's recommendation is intended to prevent genital warts and anal cancers in males, and possibly prevent head and neck cancer (though the vaccine's effectiveness against head and neck cancers has not yet been proven). (wikipedia.org)
  • colon cancer
  • These tests help prevent colon cancer by finding and removing polyps before they become cancer. (umm.edu)
  • This may reduce the chance of developing colon cancer, or at least help catch it in its most treatable stage. (umm.edu)
  • Those with a family history of colon cancer or colon polyps may need to be screened at an earlier age or more often. (umm.edu)
  • surgery
  • Cancers of this region, particularly the tongue, are more frequently treated with surgery than are other head and neck cancers. (wikipedia.org)
  • Surgery is the only treatment that can cure pancreatic adenocarcinoma, and may also be done to improve quality of life without the potential for cure. (wikipedia.org)
  • colonoscopy
  • In rare cases, when polyps are very likely to turn into cancer or too large to remove during colonoscopy, the doctor will recommend a colectomy . (umm.edu)
  • include
  • Surgeries for oral cancers include Maxillectomy (can be done with or without orbital exenteration) Mandibulectomy (removal of the mandible or lower jaw or part of it) Glossectomy (tongue removal, can be total, hemi or partial) Radical neck dissection Mohs procedure Combinational e.g., glossectomy and laryngectomy done together. (wikipedia.org)
  • cause
  • The exact cause of adenocarcinoma of kidney is still unknown. (petmd.com)
  • The exact cause of gastroesophageal junction adenocarcinomas is unknown, but certain factors can increase the risk of developing them. (medicinenet.com)
  • Together they are the seventh most frequent cancer and the ninth most frequent cause of death from cancer. (wikipedia.org)
  • Before the 1930s, in much of the world, including most Western developed countries, it was the most common cause of death from cancer. (wikipedia.org)
  • Pancreatic cancer is the fifth most common cause of death from cancer in the United Kingdom, and the fourth most common in the United States. (wikipedia.org)
  • cases
  • About 10% of cases run in families and between 1% and 3% of cases are due to genetic syndromes inherited from a person's parents such as hereditary diffuse gastric cancer. (wikipedia.org)
  • The most common, pancreatic adenocarcinoma, accounts for about 85% of cases, and the term "pancreatic cancer" is sometimes used to refer only to that type. (wikipedia.org)
  • most cases in the developed world are adenocarcinomas. (wikipedia.org)
  • People
  • However, less than 1 in every 50 people referred for endoscopy due to indigestion has cancer. (wikipedia.org)
  • The risk of developing pancreatic cancer is lower among non-smokers, and people who maintain a healthy weight and limit their consumption of red or processed meat. (wikipedia.org)
  • risk
  • Gastroesophageal reflux disease and Barrett's esophagus are conditions that increase the risk of developing gastroesophageal junction adenocarcinomas. (medicinenet.com)
  • Polyps bigger than 1 centimeter (cm) have a higher cancer risk than polyps smaller than 1 centimeter. (umm.edu)
  • A Mediterranean diet lowers the risk of cancer as does the stopping of smoking. (wikipedia.org)
  • The role of other risk factors in gastric cancer such as salt-preserved food, smoking, auto-immune gastritis are not well studied in SRCC. (wikipedia.org)
  • medical
  • medical citation needed] The initial work-up of a cancer of unknown primary includes a CT scan of the chest, abdomen, and pelvis, with IV contrast. (wikipedia.org)