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  • tissues
  • Cancer is a word applied to different types of abnormal, unhealthy cells that grow in an uncontrolled way in the body's tissues. (jamanetwork.com)
  • In this devastating syndrome, the patient's tissues come under a vicious and enduring assault by the transplanted cells. (medicalxpress.com)
  • But the immune system attacks not only infectious bugs or cancerous cells but any cells that it perceives as "foreign," including healthy cells bearing surface features the immune system hasn't become accustomed to over the course of its long-term exposure to the body's various tissues. (medicalxpress.com)
  • So, the occupying army of immune cells from the donor all too often mounts a vicious, enduring, all-fronts attack on the recipient's healthy tissues. (medicalxpress.com)
  • demonstrate a generalized method for organ bud formation from diverse tissues by combining pluripotent stem cell-derived tissue-specific progenitors or relevant tissue samples with endothelial cells and mesenchymal stem cells. (wikipedia.org)
  • The diagnosis of CLL is based on the demonstration of an abnormal population of B lymphocytes in the blood, bone marrow, or tissues that display an unusual but characteristic pattern of molecules on the cell surface. (wikipedia.org)
  • Tissue resident memory T cells (TRM) occupy tissues (skin, lung, etc..) without recirculating. (wikipedia.org)
  • liver
  • Liver disease and transplantation. (medicaltourismtoindia.com)
  • We are equipped with the latest and the best equipments to offer 360 degree care in liver disease and transplantation and to provide a multi-disciplinary, highly skilled state of-the-art service to patients, supported by cutting-edge technology and infrastructure aiming at results that are truly exemplary. (medicaltourismtoindia.com)
  • Fetal liver kinase-1 (Flk-1) is a cell surface receptor protein that is commonly used as a marker for ESCs and EPCs. (wikipedia.org)
  • Treatment
  • Called Kymriah, this is the first gene therapy that the FDA has ever cleared for the treatment of a cancer. (labroots.com)
  • Current approaches to the treatment of cancer involve killing cancer cells with toxic chemicals, radiation or surgery. (accessexcellence.org)
  • Doctors or the bone marrow transplant team will discuss the risk of complications of this treatment with the patient prior to undertaking treatment. (indianmedtrip.com)
  • The B-Cell Lymphoma Moon Shot is revolutionizing the conventional medical research approach to rapidly translate findings into patient treatment options and develop personalized therapeutic strategies. (mdanderson.org)
  • Two of the first three patients treated with the protocol at HUP - whose cases were detailed in the New England Journal of Medicine and Science Translational Medicine in August 2011 - remain healthy and in full remissions more than two years after their treatment, with the engineered cells still circulating in their bodies. (healthcanal.com)
  • In the patients who experienced complete remissions after treatment, the CAR T cells exhibited vigorous proliferation after infusion, with the most robust expansion activity usually occurring between 10 and 31 days after infusion. (healthcanal.com)
  • For patients with severe disorders of the blood, like leukaemia , a bone marrow stem cell transplant is often the only possible treatment. (sciencelearn.org.nz)
  • It takes its name from the abnormally high numbers of white blood cells found in patients' blood before treatment. (encyclopedia.com)
  • Elorac, Inc. Announces Orphan Drug Designation for Novel Topical Treatment for Pruritus in Cutaneous T-cell Lymphoma (CTCL) website Turgeon, Mary Louise (2005). (wikipedia.org)
  • Stem cell transplantation may be used if the disease recurs following standard treatment. (wikipedia.org)
  • Highlights and ongoing studies include these projects: 2017 - CAR-T cell therapy and using Zika virus to fight brain cancer In a clinical trial at Siteman, at least 16 of 20 people who received a new treatment called CAR-T cell therapy saw their cancers disappear after treatment. (wikipedia.org)
  • CIK cells are being studied intensely as a possible therapy treatment for cancer and other types of viral infections. (wikipedia.org)
  • Early recognition of coeliac disease, particularly with a focus on DQ2 homozygotes and in affected family members, is the only effective prevention, though bone marrow transplant was suggested as a treatment during early RCD2. (wikipedia.org)
  • interfere
  • While supplements and herbal therapies may be an important component of a comprehensive cancer care program, some supplements and herbs may interfere with conventional cancer care, and new research about these interactions is emerging every day. (umm.edu)
  • What's exciting about these studies is that they demonstrate our increasingly sophisticated understanding of what causes a cell to become cancerous, as well as our ability to interfere with the process," said Dr. Lynn Mara Schucter, University of Pennsylvania Cancer Center, Philadelphia, PA. (accessexcellence.org)
  • malignant
  • In another study, Italian researchers reported that adding recombinant interferon to standard surgical therapy greatly improved survival rates in patients with one of the fastest growing types of cancers, malignant melanoma. (accessexcellence.org)
  • Janet D. Rowley, a University of Chicago researcher, determined the chromosome to result from a translocation, in which portions of two chromosomes exchange places, causing cells to turn malignant. (wikipedia.org)
  • antigen receptor
  • The vector encodes an antibody-like protein, called a chimeric antigen receptor (CAR), which is expressed on the surface of the T cells and designed to bind to a protein called CD19. (healthcanal.com)
  • Polymerase chain reaction (PCR) for antigen receptor rearrangements (PARR) identifies circulating tumour cells based on unique genetic sequences. (wikipedia.org)
  • tissue
  • Bone marrow is a soft, sponge-like tissue in the centre of bones where blood cells are made. (sciencelearn.org.nz)
  • If the HLAs don't match, the donated bone marrow stem cells may attack the recipient's tissue. (sciencelearn.org.nz)
  • For this reason, the pathologist will examine the surgical specimen to determine if a margin of healthy tissue is present, thus decreasing the chance that microscopic cancer cells are left in the patient. (wikipedia.org)
  • Yet further treatments using stem cells could potentially be developed due to their ability to repair extensive tissue damage. (wikipedia.org)
  • Adult stem cells are generally limited to differentiating into different cell types of their tissue of origin. (wikipedia.org)
  • Lymphopoiesis is now usually used interchangeably with the term "lymphocytopoiesis" - the making of lymphocytes - but other sources may distinguish between the two, stating that "lymphopoiesis" additionally refers to creating lymphatic tissue, while "lymphocytopoiesis" refers only to the creation of cells in that tissue. (wikipedia.org)
  • They are derived from one or a few cells from a tissue, embryonic stem cells or induced pluripotent stem cells, which can self-organize in three-dimensional culture owing to their self-renewal and differentiation capacities. (wikipedia.org)
  • The phenomena of mechanically dissociated cells aggregating and reorganizing to reform the tissue they were obtained from subsequently led to the development of the differential adhesion hypothesis by Malcolm Steinberg. (wikipedia.org)
  • With the advent of the field of stem cell biology, the potential of stem cells to form organs in vitro was realized early on with the observation that when stem cells form teratomas or embryoid body, the differentiated cells can organize into different structures resembling those found in multiple tissue types. (wikipedia.org)
  • Subsequently, numerous new populations of memory T cells were discovered including tissue-resident memory T (Trm) cells, stem memory TSCM cells, and virtual memory T cells. (wikipedia.org)
  • lymphoma
  • Cutaneous T cell lymphoma (CTCL) is a class of non-Hodgkin lymphoma, which is a type of cancer of the immune system. (wikipedia.org)
  • Cutaneous T-cell lymphoma may be divided into the several subtypes. (wikipedia.org)
  • Enteropathy-associated T-cell lymphoma (EATL), also enteropathy-type T-cell lymphoma (ETTL), is a type of T-cell lymphoma that affects the small intestine. (wikipedia.org)
  • It is the most common primary gastrointestinal T-cell lymphoma, arising from the T cells that are found between the cells that line the small intestinal (brush border cells or small intestinal epithelial cells). (wikipedia.org)
  • EATL can be classified as an extranodal peripheral T cell lymphoma, a category it shares with hepatosplenic T cell lymphoma and panniculitic T cell lymphoma. (wikipedia.org)
  • Enteropathy associated T-cell lymphoma (EATL) is environmentally induced as a result of the consumption of Triticeae glutens (e.g. wheat gluten). (wikipedia.org)
  • Likewise, a recent study suggests that high dose therapy and autologous stem cell transplantation results in favorable outcomes for elderly patients with Non-Hodgkin's Lymphoma. (wikipedia.org)
  • The peripheral index for T-cell lymphoma is useful in defining prognosis for enteropathy-associated T-cell lymphoma. (wikipedia.org)
  • Autologous stem cell transplantation is feasible for selected patients with enteropathy-associated T-cell lymphoma and can yield durable disease control in a significant proportion of these patients. (wikipedia.org)
  • Approximately 70 percent are B-cell lymphoma. (wikipedia.org)
  • Lymphoma is the most common cancerous cause of hypercalcemia (high blood calcium levels) in dogs. (wikipedia.org)
  • Lymphoma in the bone marrow causes anemia, low platelet count, and low white blood cell count. (wikipedia.org)
  • Lymphoma is a group of blood cancers that develop from lymphocytes (a type of white blood cell). (wikipedia.org)
  • In some non-Hodgkin lymphomas, an increased amount of protein produced by the lymphoma cells causes the blood to become so thick that plasmapheresis is performed to remove the protein. (wikipedia.org)
  • Classification systems generally classify lymphoma according to: Whether or not it is a Hodgkin lymphoma Whether the cell that is replicating is a T cell or B cell The site from which the cell arises Lymphoma can also spread to the central nervous system, often around the brain in the meninges, known as lymphomatous meningitis (LM). (wikipedia.org)
  • A Hodgkin lymphoma is marked by the presence of a type of cell called the Reed-Sternberg cell. (wikipedia.org)
  • effector cells
  • Microglia are extremely sensitive forms of effector cells, because they must be alert enough to address possible life-threatening damage. (wikipedia.org)