Cell SurvivalVernoniaCell Line, TumorNeoplasmsApoptosisSurvival RateCell ProliferationSignal TransductionAntineoplastic AgentsBreast NeoplasmsGene Expression Regulation, NeoplasticNeoplasm ProteinsCell Transformation, NeoplasticTumor Cells, CulturedDisease-Free SurvivalCell LineTumor Markers, BiologicalModels, BiologicalSurvivalRNA, MessengerSurvival AnalysisGraft SurvivalTime FactorsTreatment OutcomeCells, CulturedCell DeathKaplan-Meier EstimateProto-Oncogene Proteins c-aktRetrospective StudiesPhosphorylationProto-Oncogene ProteinsPhosphatidylinositol 3-KinasesProtein-Serine-Threonine KinasesNeoplasm StagingRNA, Small InterferingProportional Hazards ModelsMice, Inbred C57BLBlotting, WesternFollow-Up Studiesbcl-X ProteinMice, KnockoutProto-Oncogene Proteins c-bcl-2bcl-Associated Death ProteinAntineoplastic Combined Chemotherapy ProtocolsImmunohistochemistryEnzyme ActivationLung NeoplasmsCombined Modality TherapyCaspase 3MutationPrognosisAutophagyTransfectionCell DivisionCaspasesReverse Transcriptase Polymerase Chain ReactionNF-kappa BCell DifferentiationMice, TransgenicRNA InterferenceApoptosis Regulatory ProteinsAdenocarcinomaEnzyme InhibitorsUp-RegulationTumor Suppressor Protein p53Gene Expression RegulationNeoplasm MetastasisDose-Response Relationship, DrugNeoplasm Recurrence, LocalIn Situ Nick-End LabelingCisplatinMultivariate AnalysisDNA-Binding ProteinsCell CycleGene Knockdown TechniquesDown-RegulationRadiation ToleranceDisease ProgressionChromonesDNA DamageCytoprotectionDrug Resistance, NeoplasmBrain NeoplasmsDisease Models, AnimalCell HypoxiaMorpholinesNeuronsTranscription FactorsDoxorubicinInhibitor of Apoptosis ProteinsOxidative StressLiver NeoplasmsGene ExpressionMembrane ProteinsMitogen-Activated Protein KinasesB-Cell Activating FactorMice, NudeMitochondriaMice, Inbred BALB CDose-Response Relationship, Radiation