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  • bone
  • Depending on the nature of the myeloproliferative neoplasm, diagnostic tests may include red cell mass determination (for polycythemia), bone marrow aspirate and trephine biopsy, arterial oxygen saturation and carboxyhaemoglobin level, neutrophil alkaline phosphatase level, vitamin B 12 (or B 12 binding capacity), serum urate or direct sequencing of the patient's DNA. (wikipedia.org)
  • Melanoma
  • The Center aims to maximize the advances of immunotherapy and take advantage of the growing enthusiasm in the field, spurred by recent successes with vaccine therapies in prostate cancer and immune modulating monoclonal antibodies in malignant melanoma. (dana-farber.org)
  • Currently, antibodies that block PD-1 and boost the immune defenses are showing great promise as treatments for melanoma and other cancers. (dana-farber.org)
  • Dana-Farber physician-scientists are leaders of clinical trials that have shown the effectiveness of Provenge, a vaccine for treating prostate cancer , and ipilimumab, a monoclonal antibody that is helping some patients with advanced melanoma survive for as long as 10 years. (dana-farber.org)
  • clinical
  • YM has reported positive results from a Phase 1/2 clinical trial of CYT387 in 166 patients with myelofibrosis, a life-threatening myeloproliferative disease. (benzinga.com)
  • Developed by the Leukaemia Foundation in consultation with people living with a blood cancer, Leukaemia Foundation support staff, haematology nursing staff and/or Australian clinical haematologists. (leukaemia.org.au)
  • The Center for Immuno-Oncology conducts clinical trials for a variety of cancers using immunotherapy. (dana-farber.org)
  • The Center for Immuno-Oncology (CIO) conducts clinical studies in one of the most exciting areas of cancer research today: unleashing the power of the body's immune system to detect and combat tumors. (dana-farber.org)
  • The Center fosters collaborative research among laboratory and clinical investigators in many different departments at Dana-Farber/Brigham and Women's Cancer Center (DF/BWCC). (dana-farber.org)
  • immunotherapy
  • Specialists are moving these immunotherapy strategies toward other cancers with the aim of optimizing treatment for a wide range of cancers. (dana-farber.org)
  • Dana-Farber has a history of important discoveries about the immune system, laying the groundwork for today's promising developments in immunotherapy for cancer and other diseases. (dana-farber.org)
  • Congenital
  • Children with secondary MDS resulting from congenital diseases of the marrow may also be offered an allogeneic transplant as a treatment option. (leukaemia.org.au)
  • progression
  • Additional studies revealed that a Jak inhibitor called ruxolitinib was highly active in slowing disease progression in both Ph-like-ALL and ETP-ALL disease models. (chop.edu)
  • Courses repeat every 6 weeks in the absence of disease progression or unacceptable toxicity. (knowcancer.com)
  • extramedullary
  • The myeloproliferative phenotype, which was associated with extramedullary hematopoiesis in the spleen and liver, was confirmed by histopathologic and flow cytometric analysis. (jove.com)
  • systemic
  • Broadly, the present invention is directed to the use of egg antibody preparations in the treatment of systemic disease in human and non-human mammals. (google.it)
  • The antibodies are then administered orally to a mammal suffering from an infectious systemic disease caused or exacerbated by such pathogenic organism or organisms. (google.it)
  • 1. A method for treating systemic manifestations of an infectious non- intestinal disease associated with pathogenic organisms or molecules in a mammal, said method comprising orally administering to said mammal IgY antibodies obtained from the egg of a domestic fowl hen which has been actively immunized against said pathogenic organisms by injection of the hen with an immunogen containing immunogenic determinants specific to elicit said antibodies. (google.it)
  • Systemic mycotic diseases (e.g., histoplasmosis, blastomycosis, coccidioidomycosis) cause antibiotic unresponsive fever and should be included in the differential list for patients residing in or having traveled through regions endemic for these agents. (vin.com)
  • therapies
  • Other studies are currently underway to identify novel targeted cancer therapies that can be used to safely and effectively treat high-risk subsets of pediatric ALL. (chop.edu)
  • Lung Cancer
  • FGFR dependency in FGFR1 -amplified lung cancer is defined by multiple genetic factors including ligand-mediated FGFR signaling and MYC overexpression. (aacrjournals.org)
  • molecular
  • PhD candidates are encouraged to take an active role in the School's research community in areas of cancer cell biology, cardiovascular disease, microbiology and molecular biology. (anglia.ac.uk)
  • Biomedical Science explores the processes of disease, from the molecular and cellular to the organ and organism level. (anglia.ac.uk)
  • Today, personalized medicine, informed by a molecular understanding of disease, has brought new classification systems as well as more effective preventive and therapeutic interventions. (pubmedcentralcanada.ca)
  • Pathways
  • Using mouse xenograft models of ALL, researchers at the Center for Childhood Cancer Research, including David T. Teachey, MD , and Shannon L. Maude, MD, PhD , found that both Ph-like ALL and ETP-ALL have dysregulated cell signaling in MAPK, JAK/STAT and PI3K/AKT/mTOR pathways. (chop.edu)
  • prevention
  • The Mayo Clinic Cancer Center receives funding from the National Cancer Institute and is designated as a comprehensive cancer center - recognition for an institution's scientific excellence and multidisciplinary resources focused on cancer prevention, diagnosis and treatment. (mayoclinic.org)
  • Personalized medicine uses traditional, as well as emerging concepts of the genetic and environmental basis of disease to individualize prevention, diagnosis and treatment. (pubmedcentralcanada.ca)
  • treat
  • Personalized medicine is "a form of medicine that uses information about a person's genes, proteins, and environment to prevent, diagnose, and treat disease" (National Cancer Institute 2011 ). (pubmedcentralcanada.ca)
  • These tests provide more information about the exact type of disease your child has, the likely course of the disease and the best way to treat it. (leukaemia.org.au)
  • Health
  • Biomedical science explores our understanding of health, disease and ageing in human, animal and microbial systems. (anglia.ac.uk)
  • In December 2008, a multidisciplinary work shop was convened by the National Institutes of Health and the Centers for Disease Control to review the scientific foundation for using personalized genomics as a component in personalized medicine. (pubmedcentralcanada.ca)