Myeloproliferative DisordersMyelodysplastic-Myeloproliferative DiseasesMyelodysplastic SyndromesLeukemia, Myelomonocytic, ChronicAnemia, RefractoryThrombocytosisAnemia, SideroblasticPolycythemia VeraJanus Kinase 2Primary MyelofibrosisThrombocythemia, EssentialLeukemia, Myelogenous, Chronic, BCR-ABL PositiveLeukemia, Myelomonocytic, JuvenileSplenomegalyHematopoiesis, ExtramedullaryFusion Proteins, bcr-ablReceptors, ThrombopoietinBone MarrowGenes, ablLeukocytosisOncogene Proteins, FusionSTAT5 Transcription FactorLeukemia, Myeloid, AcuteHematopoietic Stem Cellsfms-Like Tyrosine Kinase 3MutationBone Marrow TransplantationBone Marrow CellsCell Transformation, NeoplasticGene Expression Regulation, LeukemicLeukemiaAnemia, Refractory, with Excess of BlastsBenzamidesMyeloid CellsHematopoiesisPyrimidinesRetroviridaeTranslocation, GeneticLeukemia, Myeloid, Chronic, Atypical, BCR-ABL NegativeMutation, MissenseReceptors, ErythropoietinPiperazinesLeukemia, MyeloidMice, Inbred C57BLSignal TransductionDisease Models, AnimalBone Marrow NeoplasmsProtein-Tyrosine KinasesTransduction, GeneticCell ProliferationProto-Oncogene ProteinsMice, KnockoutChromosomes, Human, Pair 5PhenotypeFlow CytometryMice, Inbred BALB CLeukemia, Neutrophilic, ChronicMice, TransgenicCell Line, TumorMegakaryocytesBlast CrisisKaryotypingCells, CulturedSarcoma Viruses, MurineChromosome AberrationsGranulocytesPrognosis