AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesDisciplines and OccupationsAnthropology, Education, Sociology and Social PhenomenaHumanitiesInformation ScienceNamed GroupsHealth CareGeographicals
Early Detection of CancerProstatic NeoplasmsOvarian NeoplasmsBreast NeoplasmsLung NeoplasmsStomach NeoplasmsColonic NeoplasmsNeoplasm MetastasisNeoplasm InvasivenessPancreatic NeoplasmsNeoplasmsGene Expression Regulation, NeoplasticMice, NudeCancer VaccinesNeoplasm ProteinsUterine Cervical NeoplasmsSurvival AnalysisGenetic Predisposition to DiseaseSurvival RatePrognosisAntineoplastic AgentsAntineoplastic Combined Chemotherapy ProtocolsDrug Resistance, NeoplasmCarcinomaUrinary Bladder NeoplasmsCarcinoma, Non-Small-Cell LungCarcinoma, Squamous CellNational Cancer Institute (U.S.)Disease ProgressionRiskReverse Transcriptase Polymerase Chain ReactionFollow-Up StudiesCell Line, TumorColorectal NeoplasmsRetrospective StudiesReceptors, EstrogenGene Expression ProfilingRegistriesXenograft Model Antitumor AssaysTumor Markers, BiologicalProspective StudiesMutationNeoplasm StagingRNA, MessengerSurvivorsReceptor, erbB-2Risk AssessmentUnited StatesRectal NeoplasmsNeoplasm Recurrence, LocalNeoplasm TransplantationDisease-Free SurvivalCombined Modality TherapyProstate-Specific AntigenDNA, NeoplasmBlotting, WesternCell Transformation, NeoplasticEndometrial NeoplasmsOdds RatioAge FactorsRNA, Small InterferingDNA MethylationSmokingChemotherapy, AdjuvantTumor Suppressor Protein p53Esophageal NeoplasmsFluorouracilCell SurvivalTamoxifenMedical OncologyTransplantation, HeterologousNeoplastic Stem CellsSensitivity and SpecificityCisplatinReceptors, ProgesteroneAntineoplastic Agents, PhytogenicGenotypeCell MovementGenes, BRCA1MammographyAntineoplastic Agents, HormonalDown-RegulationAntigens, NeoplasmMultivariate AnalysisBreastOligonucleotide Array Sequence AnalysisKaplan-Meier EstimateRisk FactorsQuestionnairesTumor BurdenSEER ProgramDrug Screening Assays, AntitumorHead and Neck NeoplasmsLiver NeoplasmsCell DivisionAnticarcinogenic AgentsAdenocarcinomaMouth NeoplasmsNeoplasms, Hormone-DependentPolymorphism, Genetic
TumorsCervical cancerBreast cancerSkin cancersSquamous cellMetastaticNaturallyInhibitorsLungMutationsTreatmentsSymptomsTherapiesIncidencePatientsAbnormalSymptomCenters for DiseasAdjuvantPatient's cancerColorectal CancerPancreatic cancerProstate cancerCommonCommonlyExposurePeople diagnosedSuspected cancer clustersAdipose TissueClinicalCellsReplicationEndometrialCondition that occursScreeningCarcinogenPreventionTreatmentDiseasesResearchersDeaths occurredDigestiveOncologyRefersChildhoodRiskHealthEarlyThyroidHeadachesFukushimaTypesAmerican CancerStrokeCarcinomaDiseaseYearsDetectionScientists
Tumors12
  • The DDP human homologs are over-represented in known cancer drivers, and their RNAs in tumors predict heavy mutagenesis and a poor prognosis. (wikipedia.org)
  • This is COOL SCIENCE: Cristae inside mitochondria (purple) align themselves to keep "feeding" certain lung cancer tumors. (cancer.org)
  • The latest advances in cancer sequencing, and the availability of a wide range of methods to infer the evolutionary history of tumors, have made it important to evaluate, reconcile and cluster different tumor phylogenies. (biorxiv.org)
  • The rise in rates of thyroid cancer appears to be leveling off in recent years, and there is a decrease in the rate of thyroid tumors less than 1 centimeter in size. (oncolink.org)
  • These tumors were found to occur predominantly at the interface between fibroglandular and adipose tissue. (johnshopkins.edu)
  • Cancer researchers have come to understand tumors not as lumps of identical cells, but rather as diverse, dynamic populations unto themselves. (upenn.edu)
  • More than 95 percent of pancreatic cancers (tumors) form in the gland's exocrine cells, usually in the ducts. (cancercare.org)
  • Tumors that form in endocrine cells are called neuroendocrine (or islet-cell) tumors, and account for less than 5 percent of all pancreatic cancers. (cancercare.org)
  • If you've received a diagnosis of a stage 3 cancer and larger tumors, you may go straight to systemic treatment before getting surgery. (healthline.com)
  • The National Cancer Institute defines these terms in the following way A cytotoxic agent is toxic to tumors in laboratory cultures. (healthy.net)
  • Tumors can occur at any age. (medlineplus.gov)
  • Brainstem gliomas are very rare tumors that occur almost only in children. (medlineplus.gov)
Cervical cancer12
  • It also can be used for gynecologic cancers such as cervical cancer and uterine (endometrial) cancer , as well as breast cancer , lung cancer , rectal cancer , eye cancer , and skin cancer . (mskcc.org)
  • Human Papillomavirus (HPV) is a vaccine-preventable infection that can lead to cervical cancer, which is the fourth most common cancer among women worldwide. (cdc.gov)
  • CDC works with partners to help protect those most at risk from cervical cancer. (cdc.gov)
  • About 90% of cases and deaths from cervical cancer occur in low- and middle-income countries. (cdc.gov)
  • Cervical cancer claims the lives of more than 300,000 women worldwide each year. (cdc.gov)
  • In 2020, about 90% of new cases and deaths from cervical cancer occurred in low- and middle-income countries, where there is limited access to HPV vaccination, preventative screenings, and treatment. (cdc.gov)
  • The Cervical Cancer Elimination Initiative calls for vaccinating 90% of girls worldwide by age 15, along with screening and treatment. (cdc.gov)
  • In addition to preventing cervical cancer, the HPV vaccine has other benefits, including preventing genital warts and other forms of cancer caused by HPV. (cdc.gov)
  • CDC works with partners to increase HPV vaccination coverage to protect women around the world from cervical cancer. (cdc.gov)
  • It is not clear yet whether the physical status of HPV in OPSCC is similar to what is found in cervical cancer. (elsevierpure.com)
  • Conclusion: Our results are thus different from what is routinely observed in cervical cancer where HPV is almost always integrated into the human genome with loss of episomal HPV sequences. (elsevierpure.com)
  • The assistance provided by UNICEF and UNFPA for finalizing the injury and cervical cancer sections, respectively, is also appreciated. (who.int)
Breast cancer62
  • THOUSAND OAKS, Calif.--(BUSINESS WIRE)--Dec. 10, 2004-- Amgen Inc. (Nasdaq:AMGN), the world's largest biotechnology company, today announced that new data from a Phase 3 study show that the majority of neutropenic complications occur in the first cycle of chemotherapy treatment for breast cancer patients who are not administered Neulasta(R) (pegfilgrastim). (amgen.com)
  • Hospitalization and the use of intravenous anti-infectives in breast cancer patients were also significantly lower in the group receiving Neulasta in the first and subsequent cycles of chemotherapy. (amgen.com)
  • The results were presented by the study's lead investigator, Charles Vogel, M.D., Cancer Research Network, Plantation, Fla., at the 27th Annual San Antonio Breast Cancer Symposium (SABCS). (amgen.com)
  • Breast cancer patients (Stage 1-4, ECOG performance of 0-2) receiving 100 mg/m(2) docetaxel every three weeks for up to four cycles were randomized to receive either 6 mg Neulasta (n=463) or placebo (n=465) once-per-cycle on the day after docetaxel administration for up to four cycles. (amgen.com)
  • Breast cancer was diagnosed in more than 220,000 women in 2011. (ocbreastwellness.com)
  • Find out in which five states a breast cancer diagnosis is the most common, as well as what current and developing therapies are being used to treat this terrible disease. (ocbreastwellness.com)
  • With the exception of certain types of skin cancers, breast cancer is the most commonly diagnosed cancer in women. (ocbreastwellness.com)
  • Though the disease is by no means relegated just to women - more than 2,000 cases were diagnosed in men in 2011 - women do account for about 99% of all breast cancer diagnoses (220,097 in 2011) according to statistics from the Centers for Disease Control and Prevention. (ocbreastwellness.com)
  • Based on a study published in Dec. 2012 in the American Journal of Managed Care , the direct costs of treating breast cancer totaled $16.5 billion in 2010. (ocbreastwellness.com)
  • Though roughly one in eight women will develop invasive breast cancer at some point during their lifetime, and breast cancer can happen to anyone throughout the U.S., there are a few states that stand out as well above average when it comes to female breast cancer incidence rates. (ocbreastwellness.com)
  • There's not too much in common with these states other than the fact that they're in the upper half of the country (from a geographic standpoint), which leads me to one of my key points about breast cancer: Researchers aren't exactly sure why some women get breast cancer and others don't. (ocbreastwellness.com)
  • doctors do have a general idea about some of the primary risk factors for breast cancer, which include age, genetics, whether or not a patient is a smoker and/or is overweight, and even whether or not hormone replacement therapy was previously used. (ocbreastwellness.com)
  • But, the fact remains that there's no certainty in determining whether or not one woman will get breast cancer and another one won't. (ocbreastwellness.com)
  • Although that uncertainty might be scary, we're also seeing a bright side to multiple decades of therapeutic research into treating breast cancer. (ocbreastwellness.com)
  • Since 1975-1977, the five-year survival rate for women diagnosed with breast cancer has jumped from just 75% to 90% as of 2002-2008. (ocbreastwellness.com)
  • Let's have a quick look at some of the key therapies playing a role in improving patients' quality of life and look at two experimental therapies currently in clinical trials that may have the potential to dramatically alter breast cancer patients' chances for survival in the not-so-distant future. (ocbreastwellness.com)
  • Perhaps no drug has played a larger role over the past 15 years for breast cancer patients than Roche's ( NASDAQOTH:RHHBY ) Herceptin. (ocbreastwellness.com)
  • It's currently approved to treat metastatic and adjuvant breast cancer, as well as gastric cancer. (ocbreastwellness.com)
  • Just last year, the drug was approved as a neoadjuvant treatment in combination with Herceptin and docetaxel in locally advanced or early-stage HER2-positive breast cancer patients who are at a high risk of having their cancer return or spread. (ocbreastwellness.com)
  • Chemotherapy-associated ovarian damage has been associated with alkylating chemotherapy for breast cancer or Hodgkin's lymphoma, and can result in infertility and premature menopause. (cancertherapyadvisor.com)
  • MONDAY, Sept. 9New breast cancer research reveals a significant death rate among women under 50 who forgo regular mammograms and casts doubt on recent screening guidelines from a U.S. panel of experts. (ladylively.com)
  • More than 40,000 women die of breast cancer in the United States each year. (ladylively.com)
  • For the new study, published online Sept. 9 in the journal Cancer , researchers evaluated more than 600 breast cancer deaths, looking back at mammography records and other details. (ladylively.com)
  • Half of all the breast cancer deaths occurred in women under age 50, while only 13 percent of the women who died of breast cancer were 70 and older. (ladylively.com)
  • For the study, Cady and his colleagues tracked invasive breast cancer cases from their diagnoses, between 1990 and 1999, until 2007. (ladylively.com)
  • Overall, the study also showed an increase in breast cancer survival coinciding with the emergence of mammography. (ladylively.com)
  • Half of women diagnosed with breast cancer in 1969 died within 13 years after diagnosis, compared to about 9 percent of those diagnosed between 1990 and 1999 who were included in this study. (ladylively.com)
  • Although some experts have credited the decline in breast cancer death rates to improved treatments, the study shows that's not the whole story, Monsees said. (ladylively.com)
  • The bottom line: "Screening doesn't reduce the risk of getting breast cancer, but it does reduce the risk of dying from it," Monsees said. (ladylively.com)
  • Robert Smith, director of screening for the American Cancer Society, offered this perspective: "Regular screening was associated with a much, much lower likelihood of dying [from breast cancer]," compared to no screening or long-ago screening. (ladylively.com)
  • Although this shows that getting regular mammograms doesn't entirely eliminate the risk of dying from breast cancer, Smith said, "the message here is that mammography is a good part of your prevention plan. (ladylively.com)
  • Patients and Methods Pretreatment breast DCE-MRI images of 294 patients with biopsy-proven invasive breast cancer from 2008 to 2014 were studied. (johnshopkins.edu)
  • Conclusion Invasive breast cancer preferably and predominantly occurs adjacent to breast adipose tissue. (johnshopkins.edu)
  • Clinical Breast Cancer , 17 (1), e11-e18. (johnshopkins.edu)
  • Text Mining in Electronic Medical Records Enables Quick and Efficient Identification of Pregnancy Cases Occurring After Breast Cancer. (bvsalud.org)
  • To apply text mining (TM) technology on electronic medical records (EMRs) of patients with breast cancer (BC) to retrieve the occurrence of a pregnancy after BC diagnosis and compare its performance to manual curation. (bvsalud.org)
  • This study aims to develop and pilot-test a specific QPL in the following two contrasting clinical contexts in France after cancer resistance has developed: triple-negative and luminal B metastatic breast cancer (MBC) and metastatic uveal melanoma (MUM). (researchprotocols.org)
  • Getting a diagnosis of breast cancer while you're pregnant isn't a common occurrence. (healthline.com)
  • It's possible that breast cancer in pregnancy has increased because more women are having children later in life. (healthline.com)
  • The risk of developing breast cancer rises with a woman's age. (healthline.com)
  • Being pregnant doesn't cause breast cancer, but if you already have some breast cancer cells, the hormonal changes of pregnancy may cause them to grow. (healthline.com)
  • Continue reading to learn more about breast cancer during pregnancy, treatment options, and what you can expect for yourself and your baby. (healthline.com)
  • Diagnosing and treating breast cancer are complicated by pregnancy. (healthline.com)
  • There are no known cases of breast cancer spreading to a fetus, although there are cases where it has been found in the placenta. (healthline.com)
  • When compared with women who aren't pregnant and have similar types of breast cancer, both groups have the same general outlook. (healthline.com)
  • What are the treatment options for breast cancer during pregnancy? (healthline.com)
  • The first-line treatment for breast cancer is surgery, even if you're pregnant. (healthline.com)
  • Use of chemotherapy may depend on the specific type of breast cancer you have and how aggressive it is. (healthline.com)
  • Surgery is a primary treatment for breast cancer, regardless of whether you're pregnant. (healthline.com)
  • Not all people who receive a diagnosis of breast cancer will need chemotherapy. (healthline.com)
  • Consume foods high in vitamin E. Research shows women who regularly eat foods rich in vitamin E have a lower risk of breast cancer. (healthy.net)
  • This study aims to compare an additional support program (text message reminders and/or telephone-based counseling) with usual care in making sure breast cancer patients take their endocrine therapy medication as prescribed (medication adherence). (mayo.edu)
  • Pregnancy-associated breast cancer (PABC) is normally thought as breast cancer occurring anytime during gestation, lactation or within twelve months following delivery. (ap26113.com)
  • The U.S. Preventive Services Task Force recommends that women age 50 to 74 years undergo screening mammography every two years (biennially) to check for the presence of breast cancer. (brown.edu)
  • Breast cancer is the second leading cause of cancer-related death among women. (brown.edu)
  • Research shows that age-appropriate screening mammography reduces breast-cancer-related mortality and is cost effective, Trivedi said. (brown.edu)
  • If the cost-sharing provisions of the ACA are rescinded, our results raise concern that fewer older women will receive recommended breast-cancer screening," wrote the authors. (brown.edu)
  • In previous research, Trivedi and colleagues found that copayments of approximately $20 were associated with up to an 11-percentage-point drop in rates of breast-cancer screening. (brown.edu)
  • Five or more years of tamoxifen use increases risk of cataracts in breast cancer patients. (greenmedinfo.com)
  • Breast Cancer Res Treat. (greenmedinfo.com)
  • Tamoxifen interferes with cognitive function in breast cancer patients. (greenmedinfo.com)
  • Adjuvant tamoxifen therapy for early stage breast cancer increases the risk of second primarly malignancies such as endometrial, colon and somatch cancer. (greenmedinfo.com)
Skin cancers2
  • Most basal cell and squamous cell skin cancers can be cured . (cancer.gov)
  • Greater public awareness has led to higher rates of screening exams, self-exams, and detection of these skin cancers. (cancer.gov)
Squamous cell2
Metastatic6
  • For additional information please see Prostate Cancer: Diagnosis and Staging , a Critical Images slideshow, to help determine the best diagnostic approach for this potentially deadly disease and/or Advanced Prostate Cancer: Signs of Metastatic Disease , a Critical Images slideshow, for help identifying the signs of metastatic disease. (medscape.com)
  • This disease state is now subdivided into castrate-sensitive or castrate-resistant locally recurrent prostate cancer and castrate-sensitive or castrate-resistant metastatic prostate cancer. (medscape.com)
  • For example, Temel et al reported that in patients with metastatic non-small cell lung cancer, early palliative care led to significant improvements in both quality of life and mood. (medscape.com)
  • The American Society for Clinical Oncology (ASCO) recommends considering the combination of palliative care with standard oncology care early in the course of treatment for patients with metastatic cancer and/or a high symptom burden. (medscape.com)
  • In step 1c, 2 focus groups of patients with any type of metastatic cancer (n=4) and health care professionals (n=4) will be conducted to revise the content of a preliminary QPL and elaborate an acceptable and feasible clinical implementation. (researchprotocols.org)
  • Alternatively, so far as metastatic HER2- positive breasts cancer can be involved, trastuzumab ought to be prevented and chemotherapy could begin from the next trimester. (ap26113.com)
Naturally7
  • Normal cells naturally grow and die in the body, but cancer cells do not die at the right time and group together. (alpenaregionalmedicalcenter.org)
  • DNA damage can occur naturally or via environmental factors, but is distinctly different from mutation, although both are types of error in DNA. (wikipedia.org)
  • Damage to DNA that occurs naturally can result from metabolic or hydrolytic processes. (wikipedia.org)
  • Naturally occurring oxidative DNA damages arise at least 10,000 times per cell per day in humans and as much as 100,000 per cell per day in rats as documented below. (wikipedia.org)
  • The list below shows some frequencies with which new naturally occurring DNA damages arise per day, due to endogenous cellular processes. (wikipedia.org)
  • only trace amounts occur naturally. (cdc.gov)
  • Trace amounts of plutonium occur naturally, but large amounts have been produced in nuclear reactors. (cdc.gov)
Inhibitors1
  • Hence, the combination of ERK1/2 and ERK5 inhibitors may lead to more effective treatments for colorectal cancer patients. (genengnews.com)
Lung5
  • It's also the second-leading cancer-based cause of death for women behind only lung cancer. (ocbreastwellness.com)
  • It has been found to cause lung, liver, and bone cancer in plutonium workers. (cdc.gov)
  • The types of cancers you would most likely develop are cancers of the lung, bones, and liver. (cdc.gov)
  • Some 9% of the global disease burden of lung cancer is attributed to occupational exposure and 5% to outdoor air pollution. (who.int)
  • Cancer of the lung and mesothelioma are caused by exposure to asbestos, which remains in use in some countries. (who.int)
Mutations4
  • Moreover, none of the known similarity measures is able to manage mutations occurring multiple times in the tree, a circumstance often occurring in real cases. (biorxiv.org)
  • To overcome these limitations, in this paper we propose MP3, the first similarity measure for tumor phylogenies able to effectively manage cases where multiple mutations can occur at the same time and mutations can occur multiple times. (biorxiv.org)
  • Tim Chan and colleagues report the identification of recurrent somatic mutations in FAT1 in glioblastoma, colon cancer and head and neck cancer and show that inactivation of FAT1 promotes Wnt signaling and tumorigenesis. (nature.com)
  • Usually, mutations occur over weeks or months. (genengnews.com)
Treatments5
  • Treatments are based on the type of cancer cells in the body. (alpenaregionalmedicalcenter.org)
  • Our scientists pursue every aspect of cancer research-from exploring the biology of genes and cells, to developing immune-based treatments, uncovering the causes of metastasis, and more. (mskcc.org)
  • Most cancer-related deaths result from disseminated diseases that develop resistance to anticancer treatments. (researchprotocols.org)
  • Certain treatments for childhood cancer increase risk for digestive problems. (curesearch.org)
  • Treatments range from watchful waiting with careful follow-up for less aggressive cancers to combinations of surgery, radiation therapy, chemotherapy , and hormonal therapy for more aggressive or widespread cancers. (healthgrades.com)
Symptoms15
  • Screening is looking for cancer before a person has any symptoms . (cancer.gov)
  • By the time symptoms appear, cancer may have begun to spread. (cancer.gov)
  • Screening tests are given when you have no cancer symptoms. (cancer.gov)
  • Tests are used to screen for different types of cancer when a person does not have symptoms. (cancer.gov)
  • Additionally, people should treat symptoms as soon as they occur to lessen the risk of them worsening. (medicalnewstoday.com)
  • However, those symptoms are generally not caused by prostate cancer. (medscape.com)
  • The main reason why Japan has been able to successfully push the 2011 Fukushima nuclear power plant disaster far out of the public eye, is for the simple reason that the tragic fallout from said disaster would take many years to materialize: after all, it takes a long time between the initial irradiation to the first cancer symptoms, to the sad terminal outcome. (shtfplan.com)
  • Treatment usually occurs if symptoms develop, if there is a decrease in the red blood cell count or platelet count, or if there is enlargement of the lymph nodes or spleen. (cancercare.org)
  • Prostate cancer shares many symptoms with benign prostatic hypertrophy (BPH), which is a noncancerous enlargement of the prostate, although BPH does not cause prostate cancer. (healthgrades.com)
  • What are the symptoms of prostate cancer? (healthgrades.com)
  • At the time of diagnosis most men with prostate cancer report no symptoms. (healthgrades.com)
  • When they occur, many of the symptoms of prostate cancer are related to constriction of the urethra and involve changes in urine flow. (healthgrades.com)
  • Cancer that has spread can cause additional symptoms based on the location of spread. (healthgrades.com)
  • The symptoms of menopause, on the other hand, may begin years before the actual menopause occurs and may persist for some years afterward as well. (medicinenet.com)
  • Symptoms may be subtle and slowly become worse, or they may occur very quickly. (medlineplus.gov)
Therapies4
  • The company continues to work to bring new and innovative therapies to cancer patients that offer the potential to improve patient quality of life. (ocbreastwellness.com)
  • It could aid drug makers in designing targeted therapies that block cancer cells from multiplying. (news-medical.net)
  • Targeted therapies focus on binding to specific molecules that are important for cancer cell survival and growth. (cancercare.org)
  • Cancer can often be effectively treated with local therapies like surgery and radiation, without systemic treatment. (healthline.com)
Incidence5
  • The evidence for and against screening, a summary of screening guidelines, and the observed impact of the USPSTF guidelines on prostate cancer incidence and mortality are presented in full detail in Workup/Prostate Cancer Screening . (medscape.com)
  • The evaluation was requested because of concern of a possible increased incidence of cancer among employees exposed to metal fumes, solvents, gases, and cutting oils. (cdc.gov)
  • No significantly increased incidence of cancer in general or of any specific type was observed in the factory as a whole or in the grinding department. (cdc.gov)
  • While data on the burden and pattern of cancer in the Region are insufficient, the available studies and estimates show an increased incidence due to infectious agents and to growing tobacco and alcohol use, unhealthy diet, physical inactivity and pollution. (who.int)
  • The main factors contributing to the increasing incidence of cancer in the African Region are growing tobacco and alcohol use, unhealthy diet, physical inactivity, environmental pollution and action of infectious agents. (who.int)
Patients23
  • Many patients referred urgently by GPs as suspected cancer cases outside the terms of referral guidelines go on to have a cancer diagnosis, new research reveals. (pulsetoday.co.uk)
  • Patients in the placebo arm not only experienced significantly more neutropenic events than patients in the Neulasta arm, but more than 65 percent of these events occurred in the first cycle of treatment, emphasizing the importance of early protection," said Dr. Vogel. (amgen.com)
  • We connect patients, caregivers, and family members with essential services and resources at every step of their cancer journey. (cancer.org)
  • Although most female patients regain fertility after CHOP-like chemotherapy for aggressive lymphoma, late ovarian impairment occurs frequently. (cancertherapyadvisor.com)
  • Although most female patients regain fertility after CHOP-like chemotherapy for aggressive lymphoma , late ovarian impairment occurs frequently in these patients, a new study published online in the journal Annals of Oncology has shown. (cancertherapyadvisor.com)
  • Most patients presenting with prostate cancer do so with screen-detected cancer and are asymptomatic. (medscape.com)
  • Patients whose MRI results are highly suspicious for clinically significant prostate cancer should undergo prostate biopsy. (medscape.com)
  • Methods: The study population consisted of patients with potentially resectable pancreatic cancer treated on a phase II trial of neoadjuvant chemotherapy and chemoradiation. (psu.edu)
  • Discussion: These data suggest that body composition analysis of standard CT images may provide clinically relevant information for patients with potentially resectable pancreatic cancer who receive neoadjuvant therapy. (psu.edu)
  • In patients with advanced cancer, early initiation of palliative care is essential for optimal symptom control, expectations, illness understanding, and comprehensive care of the patient and family. (medscape.com)
  • For patients with newly diagnosed advanced cancer, the Expert Panel suggests early palliative care involvement within 8 weeks after diagnosis. (medscape.com)
  • For patients with cancer who have high symptom burden and/or unmet physical or psychosocial needs, outpatient cancer care programs should provide and use dedicated resources (palliative care clinicians) to deliver palliative care services to complement existing program tools. (medscape.com)
  • For patients with early or advanced cancer who will be receiving care from family caregivers in the outpatient setting, providers (eg, nurses, social workers) may initiate caregiver-tailored palliative care support, which could include telephone coaching, education, referrals, and face-to-face meetings. (medscape.com)
  • All cancer patients should be repeatedly screened for palliative care needs, beginning with their initial diagnosis and thereafter at intervals as clinically indicated. (medscape.com)
  • If surgery is chosen, patients should select a surgeon who has a high level of experience operating on pancreatic cancer, and who works with a dedicated hospital support team. (cancercare.org)
  • These data will be used to develop and pilot-test a QPL specific to patients with cancer experiencing initial or acquired resistance to treatment. (researchprotocols.org)
  • We expect to obtain a core QPL that comprises questions and concerns commonly expressed by patients with resistant cancer and is complemented by specific issues for either MBC or MUM cancer sites. (researchprotocols.org)
  • A clinically and culturally tailored QPL is expected to facilitate patients' participation in consultations, improve oncologists' responses to patients' information and support needs, and thus foster patients' psychological adjustment to the diagnosis and follow-up of cancer resistance to treatment. (researchprotocols.org)
  • These signaling pathways are widely expressed and known to drive cancer growth in one-third of patients with colorectal cancer (CRC). (genengnews.com)
  • Most cancer patients have no access to screening, early diagnosis, treatment or palliative care. (who.int)
  • DESIGN: In this retrospective population-based cohort study, patients were identified through the Swedish Colorectal Cancer Registry, which was also used for information on the exposure variable anastomotic leakage and covariates. (lu.se)
  • PATIENTS: All patients undergoing anterior resection for rectal cancer in Sweden from April 2011 to June 2013 were included. (lu.se)
  • We also found that individuals over the age of 50, those with weakened immune systems, such as cancer patients, and those without spleens were at highest risk for more severe illness. (cdc.gov)
Abnormal7
  • In addition, modern research has helped to clarify that cancer does not happen all at once, but rather develops from a series of genetic changes that cause precancerous cells to develop abnormal traits. (alpenaregionalmedicalcenter.org)
  • Cancer is a group of more than one hundred diseases in the body in which abnormal cells divide without control and invade neighboring tissues. (alpenaregionalmedicalcenter.org)
  • Cancer is an uncontrolled growth of abnormal cells in the body. (alpenaregionalmedicalcenter.org)
  • When abnormal tissue or cancer is found early, it may be easier to treat. (cancer.gov)
  • If a screening test result is abnormal, you may need to have more tests done to find out if you have cancer. (cancer.gov)
  • Cancer of the prostate occurs when abnormal prostate cells reproduce in an uncontrolled fashion. (healthgrades.com)
  • Cancer refers to a group of diseases characterized by abnormal cell proliferation with a tendency to invade adjacent tissues and produce metastases. (who.int)
Symptom1
Centers for Diseas1
  • The US Centers for Disease Control and Prevention (CDC) and the National Cancer Institute (NCI) define a cancer cluster as a greater-than-expected number of cancer cases that occurs within a group of people in a defined geographic area over a specific period of time . (cancer.org)
Adjuvant1
  • In these cases, chemo is used as adjuvant therapy , or to prevent cancer from returning after the tumor has been removed. (healthline.com)
Patient's cancer1
  • Partner with us to treat your patient's cancer. (mskcc.org)
Colorectal Cancer1
  • Previously, ERK5 didn't seem important in colorectal cancer. (genengnews.com)
Pancreatic cancer5
  • Background: Little is known about changes in body composition that may occur during neoadjuvant therapy for pancreatic cancer. (psu.edu)
  • Each year, more than 55,000 people in the United States-most over the age of 60-will be diagnosed with pancreatic cancer. (cancercare.org)
  • In recent years, additional treatment options have become available to people living with pancreatic cancer, and more are on the horizon. (cancercare.org)
  • About 10 to 15 percent of people diagnosed with pancreatic cancer will be candidates for a Whipple procedure (a surgery for cancer in the head of the pancreas) in which parts of the pancreas, gall bladder, bile duct and small bowel are removed. (cancercare.org)
  • A form of therapy called external beam radiation is commonly used in treating pancreatic cancer. (cancercare.org)
Prostate cancer12
Common11
  • There was no association between the proportion of urgent referrals and published cancer rates for the most common cancers. (pulsetoday.co.uk)
  • The most common type of cancer is non-Hodgkin lymphoma, which affects young people between the ages of 12 and 30. (alpenaregionalmedicalcenter.org)
  • There is a larger than expected number of a specific type of cancer (or types of cancer that are known to have a common cause). (cancer.org)
  • Skin cancer is the most common cancer in the United States. (cancer.gov)
  • Even if a cancer cluster is identified, there is no guarantee that a common cause or an environmental contaminant will be implicated. (cdc.gov)
  • in the United States, it is the most common cancer in men and the second most common cause of cancer deaths in men. (medscape.com)
  • This common female cancer is almost always caused by the human papillomavirus (HPV), but is almost completely preventable with a safe and effective HPV vaccine and screenings. (cdc.gov)
  • Cancer of the prostate is a common cancer among older men. (healthgrades.com)
  • Medulloblastomas are the most common type of childhood brain cancer. (medlineplus.gov)
  • Currently, there are 1.2 million people living with CRC in the United States, making it the third most common cancer among men and women. (genengnews.com)
  • 2. The most common cancers in the African Region are cancers of the cervix, breast, liver and prostate as well as Kaposi's sarcoma and non-Hodgkin's lymphoma. (who.int)
Commonly2
  • It is the most commonly diagnosed cancer in women aged 20 to 34 years. (oncolink.org)
  • The disease most commonly occurs among older women. (brown.edu)
Exposure5
  • If the excess cancer cases include many different types of cancer over a period of many years, it's not likely to be a true cancer cluster, or to be caused by a single environmental factor or exposure. (cancer.org)
  • The cancer may occur as soon as 5 years after exposure. (oncolink.org)
  • Exposure to higher levels could occur from an accidental release during its use. (cdc.gov)
  • The main health effect from exposure to plutonium is cancer which may occur years after exposure. (cdc.gov)
  • The highest exposure levels occur predominantly in children in developing countries. (who.int)
People diagnosed2
  • The number of people diagnosed with thyroid cancer in the United States had been rising for at least 40 years, but the number of deaths from thyroid cancer has stayed the same or decreased slightly. (oncolink.org)
  • Because of new treatment options, long-term survival and quality of life continue to improve for people diagnosed with this type of cancer. (cancercare.org)
Suspected cancer clusters2
  • About 1,000 suspected cancer clusters are reported to state health departments each year. (cancer.org)
  • Many state, local, and tribal health departments have used the 1990 Guidelines as a basis for developing and implementing protocols to investigate suspected cancer clusters, employing the four-step approach (initial response, assessment, major feasibility study, and etiologic investigation) identified in the 1990 Guidelines. (cdc.gov)
Adipose Tissue1
  • Further depletion of skeletal muscle, visceral adipose tissue, and subcutaneous adipose tissue occurred during neoadjuvant therapy, but these losses did not preclude the performance of potentially curative surgery. (psu.edu)
Clinical1
Cells22
  • The cancer cells can spread through the bloodstream and lymphatic system. (alpenaregionalmedicalcenter.org)
  • Chemotherapy involves the use of anti-cancer medicines to destroy cancer cells. (alpenaregionalmedicalcenter.org)
  • The medicines travel through the bloodstream to attack cancer cells. (alpenaregionalmedicalcenter.org)
  • When cancer cells are in a large mass, the body can no longer cope with the growth. (alpenaregionalmedicalcenter.org)
  • In replicating cells, such as cells lining the colon, errors occur upon replication past damages in the template strand of DNA or during repair of DNA damages. (wikipedia.org)
  • 10 9 apoptotic events occurring per day in human adult tissues, it is surprisingly difficult to histologically detect apoptotic cells due to the rapid recognition and clearance of apoptotic cells. (nature.com)
  • Skin cancer is a disease in which malignant (cancer) cells form in the tissues of the skin. (cancer.gov)
  • If drug makers can replicate p21's strategy in targeted cancer-fighting compounds, they could attack cancer cells' ability to reproduce at the most basic level. (news-medical.net)
  • Metastasis arises when malignant cells secrete factors through the bloodstream to distant sites in the body as a way of readying new spaces for cancer to grow. (upenn.edu)
  • To Qian and Akçay, steeped in theoretical evolutionary biology and ecology theory, this feature of cancer's spread presented interesting questions: Assuming that cancer cells must sacrifice some of their own resources to prepare these distant areas of the body, how would such a lineage compete with others that cultivated areas closer to the primary tumor? (upenn.edu)
  • MSK radiation oncologist Kathryn Beal explains how brachytherapy, a form of internal radiation, can be used to destroy lingering cancer cells after surgery. (mskcc.org)
  • The radiation given off by this source damages the DNA of nearby cancer cells. (mskcc.org)
  • Cleavage from the cell-cell adhesion molecule PTPμ occurs in human being glioblastoma multiforme mind tumor glioma and cells cell lines. (biomasswars.com)
  • Together these data suggest that distinct proteolytic cascades occur in tumor cells to generate novel PTPμ fragments. (biomasswars.com)
  • The insights gained from this study reinforce the theory of a "protease storm" occurring in cancer cells which proteolyzes cell-cell adhesion molecules such as PTPμ to promote tumorigenesis by reducing adhesion and generating biologically active fragments that can function in new potentially oncogenic ways. (biomasswars.com)
  • Chemotherapy drugs, given intravenously (through a needle into a vein) or in pill form, can kill cancer cells. (cancercare.org)
  • Purine analogs are "antimetabolites" that interfere with DNA production and halt the growth of cancer cells. (cancercare.org)
  • It recognizes and fights against danger, such as infections, viruses and growing cancer cells. (cancercare.org)
  • They're designed to kill cancer cells. (healthline.com)
  • Cancer cells grow faster than regular cells. (healthline.com)
  • The ERK pathway plays a critical role in embryonic development and tissue repair because it instructs cells to multiply and start dividing, but when overactivated cancer growth often occurs. (genengnews.com)
  • If you block one pathway, cancer cells usually mutate and find another pathway that ultimately allows for a recurrence of cancer growth," remarked co-lead study author Koji Taniguchi, M.D., Ph.D., senior researcher at the Keio University School of Medicine in Tokyo. (genengnews.com)
Replication3
  • Thus, Herceptin works by slowing the replication of HER2-positve breast cancers. (ocbreastwellness.com)
  • New research at Rice University is allowing biochemists to understand a key hierarchy of protein interactions that occurs in DNA replication, showing for the first time how a key protein "trumps" its rivals and shuts down cell division while DNA repairs take place. (news-medical.net)
  • All cancers are marked by some form of DNA replication gone awry, so a basic understanding of DNA replication is of paramount importance to those designing cancer-fighting drugs," said lead author Yousif Shamoo, assistant professor of biochemistry and cell biology. (news-medical.net)
Endometrial1
Condition that occurs2
  • Dysarthria is a condition that occurs when there are problems with the part of the brain, nerves, or muscles that help you talk. (medlineplus.gov)
  • For example, doctors may speak of a condition that occurs in 'postmenopausal women. (medicinenet.com)
Screening5
  • This information helps doctors recommend who should be screened for cancer, which screening tests should be used, and how often the tests should be done. (cancer.gov)
  • It is important to remember that your doctor does not necessarily think you have cancer if he or she suggests a screening test. (cancer.gov)
  • The American Cancer Society and other organizations, however, have continued to recommend annual screening beginning at age 40 for women at average risk. (ladylively.com)
  • Thyroid cancer screening has not been shown to decrease the chance of dying from the disease. (oncolink.org)
  • Learn more about thyroid cancer risks and screening in this expert-reviewed summary. (oncolink.org)
Carcinogen2
  • Often there's a concern that the cancers might be caused by some type of carcinogen (cancer-causing agent) in the environment. (cancer.org)
  • The Department of Health and Human Services (DHHS), International Agency for Research on Cancer (IARC), and the EPA's Office of Air and Radiation consider plutonium to be a human carcinogen. (cdc.gov)
Prevention6
  • The advancement of these techniques has led to a better understanding of the cancer process and the possible prevention and detection methods. (alpenaregionalmedicalcenter.org)
  • These new techniques enable scientists to target prevention and detection efforts at the specific genes that cause cancer. (alpenaregionalmedicalcenter.org)
  • For information about risk and protective factors for skin cancer, see Skin Cancer Prevention . (cancer.gov)
  • These interventions, with primary and secondary prevention as top priorities, and availability, affordability and accessibility of drugs for cancer treatment should be implemented and scaled up in countries. (who.int)
  • Faced with a growing burden of noncommunicable diseases (NCDs) and a high burden of communicable diseases, countries in the Region are having difficulties in providing adequate cancer prevention and treatment services. (who.int)
  • The strategy builds on an existing World Health Assembly resolution (WHA58.22 on cancer prevention and control) and past achievements in the area of NCDs and proposes a set of public health interventions aimed at reducing the burden of cancer. (who.int)
Treatment17
  • For more information about thyroid cancer , see Thyroid Cancer Treatment. (oncolink.org)
  • Most cases of thyroid cancer respond to treatment and are usually cured . (oncolink.org)
  • Reporting in the journal PLOS ONE , Qian and Akçay suggest that incorporating evolutionary and ecological theory into cancer biology may help guide more effective treatment plans. (upenn.edu)
  • Learn why brachytherapy is the best form of treatment for some cancers. (mskcc.org)
  • Brachytherapy is a cancer treatment in which radioactive material sealed inside a seed, pellet, wire, or capsule is implanted in the body using a needle or catheter. (mskcc.org)
  • [ 1 ] There is growing recognition of palliative care as an integral aspect of cancer treatment, with the ability to improve quality of life and prevent unnecessary hospital admissions and the use of health services, especially when instituted early in the course of disease. (medscape.com)
  • Inpatients and outpatients with advanced cancer should receive dedicated palliative care services early in the disease course, concurrent with active treatment. (medscape.com)
  • Treatment of CLL doesn't always occur at diagnosis. (cancercare.org)
  • Treatment for childhood cancer can sometimes cause scarring and ongoing problems in the bowel or other parts of the digestive system. (curesearch.org)
  • This innovative study provides a framework to design anticipation-based chemotherapy approaches for cancer treatment. (nature.com)
  • When coming up with a treatment plan, much will depend on extent of the cancer. (healthline.com)
  • The purpose of this trial is to identify cancer survivors who are at increased risk of developing late-occurring complications after undergoing treatment for childhood cancer. (mayo.edu)
  • A patient's genes may affect the risk of developing complications, such as congestive heart failure, heart attack, stroke, and second cancer, years after undergoing cancer treatment. (mayo.edu)
  • Anthracyclines-based regimens will be the hottest is normally breasts cancer tumor treatment and had been been shown to become connected with favourable basic safety profile when given during being pregnant. (ap26113.com)
  • It really is apparent that, analysis of breasts cancer during being pregnant adds difficulty Rabbit polyclonal to MTH1 to tumor treatment recommendations. (ap26113.com)
  • Enough knowledge and evidence exist for preventing one third of all cancers, providing effective treatment for a further one third and providing pain relief and palliative care for all cases. (who.int)
  • Evidence is also available for early detection and effective treatment and cure of a further one third of cancer cases. (who.int)
Diseases3
  • Cancer is a group of more than 100 different diseases. (cancer.org)
  • 7 diseases such as cancer and cardiovascular hospitals through a ministerial decree. (who.int)
  • Conventionally NCDs used to refer to major chronic diseases inclusive of heart disease, stroke, diabetes, cancer and chronic respiratory diseases. (who.int)
Researchers2
  • However, researchers are not sure if lupus causes these headaches or if they occur alongside lupus. (medicalnewstoday.com)
  • Researchers are currently unsure if lupus causes headaches or if they occur alongside lupus. (medicalnewstoday.com)
Deaths occurred2
  • Seventy-one percent of the deaths occurred among unscreened women, most of them younger, Cady found. (ladylively.com)
  • Thirty nine cancer deaths occurred. (cdc.gov)
Digestive2
  • What Digestive System Problems Can Occur? (curesearch.org)
  • Heavy drinkers, especially those who use tobacco, have a higher risk for cancer and other digestive system problems. (curesearch.org)
Oncology1
  • Professional oncology social workers provide free emotional and practical support for people with cancer, caregivers, loved ones and the bereaved. (cancercare.org)
Refers1
  • This refers to inflammation of the meninges that does not occur due to infection. (medicalnewstoday.com)
Childhood1
  • Genetic studies may help doctors identify survivors of childhood cancer who are more likely to develop late complications. (mayo.edu)
Risk10
Health10
  • The following sections will look at some health conditions that may occur alongside depression. (medicalnewstoday.com)
  • State and local health departments can use these guidelines to develop a systematic approach to responding to community concerns regarding cancer clusters. (cdc.gov)
  • The guidelines are intended to apply to situations in which a health department responds to an inquiry about a suspected cancer cluster in a residential or community setting only. (cdc.gov)
  • The goal is to cure the cancer, if possible, or to keep it from spreading while also protecting the health of your baby. (healthline.com)
  • Your age, the stage of the cancer, and any other health problems will all be taken into consideration before deciding on a chemo regimen. (healthline.com)
  • The Indian cooking spice turmeric, responsible for the intense color of curry, is phenomenal in its ability to promote and protect health especially against cancer. (healthy.net)
  • This is not a complete list of side effects and other serious side effects or health problems that may occur because of the use of this drug. (rxlist.com)
  • 3. Cancer control programmes should be established in a comprehensive and systematic framework and be integrated within national health plans. (who.int)
  • Furthermore, the health systems of countries are not sufficiently equipped to provide cancer services. (who.int)
  • Cancers impact negatively on the overall health status of the population in Member States and lead to loss of income and huge health expenditures. (who.int)
Early6
  • This is why early detection of cancer is critical in treating cancer. (alpenaregionalmedicalcenter.org)
  • We now show that during early apoptosis limited membrane permeabilization occurs in blebs and apoptotic bodies, which allows release of proteins that may affect the proximal microenvironment before the catastrophic loss of membrane integrity during secondary necrosis. (nature.com)
  • These results indicate that limited membrane permeabilization occurs in blebs and apoptotic bodies before secondary necrosis, leading to acute and localized release of immunomodulatory proteins during the early phase of active apoptotic membrane blebbing. (nature.com)
  • This can help find cancer at an early stage . (cancer.gov)
  • In cases of early stage cancer, an oncologist can make an informed decision about which drugs are best to use. (healthline.com)
  • Not all chemo drugs cause hair loss , but most of those mentioned above for early stage cancer will have that side effect. (healthline.com)
Thyroid2
  • Women are about three times more likely than men to have thyroid cancer. (oncolink.org)
  • Having a family history of thyroid disease or thyroid cancer. (oncolink.org)
Headaches4
  • Why do headaches occur with lupus? (medicalnewstoday.com)
  • This article discusses why headaches may occur with lupus and how people can try to manage them. (medicalnewstoday.com)
  • Over-the-counter (OTC) and prescription medications can help with both preventing and managing headaches, whether they occur due to lupus or other reasons. (medicalnewstoday.com)
  • Headaches can occur in individuals with lupus as the condition affects almost any organ in the body, including the brain. (medicalnewstoday.com)
Fukushima1
  • However, for the biggest, and most criminal, cover up by a Japanese government in recent history, the irradiated chickens are coming home to roost and earlier today Japan finally acknowledged the first "possible casualty" from radiation at the wrecked Fukushima nuclear power plant, a worker who was diagnosed with cancer after the crisis broke out in 2011. (shtfplan.com)
Types5
  • Cancer is a complex disease with over 200 different types. (alpenaregionalmedicalcenter.org)
  • The cancers should either be all of the same type or types of cancer that are known to have the same cause. (cancer.org)
  • In addition to being among the most-diagnosed cancer types, it's also quite expensive to treat. (ocbreastwellness.com)
  • Scientists are trying to better understand which people are more likely to get certain types of cancer. (cancer.gov)
  • These types of cancers have occurred in workers who were exposed to plutonium in air at much higher levels than is in the air that most people breathe. (cdc.gov)
American Cancer2
Stroke1
  • Brain injury, brain cancer, infections or a stroke are among the causes of brain injury. (selfgrowth.com)
Carcinoma1
  • In the United States, about 3 million cases of nonmelanoma skin cancer or keratinocyte carcinoma are diagnosed each year, and rates have likely been increasing for decades but have recently stabilized. (cancer.gov)
Disease2
  • Physical examination alone cannot reliably differentiate benign prostatic disease from cancer. (medscape.com)
  • Cancer genomes are now rapidly yielding to analysis, showing the heterogeneity of the mutational events and processes contributing to disease. (nature.com)
Years3
  • One-third of deaths among those who did get screened regularly were attributed to "interval cancers," those detected in between the mammograms done every two years. (ladylively.com)
  • In a study that followed children who were exposed to chemotherapy in utero for more than 18 years, none were found to have cancer or other serious abnormalities. (healthline.com)
  • Irregular periods can occur for years prior to reaching menopause. (medicinenet.com)
Detection1
  • A review of nearly 19,000 urgent referrals by GPs in 516 Scottish practices found wide variation in rates of cancer referral and subsequent detection - much unexplained. (pulsetoday.co.uk)
Scientists3