• cell
  • Gangliosides perform important functions through carbohydrate-specific interactions with proteins, for example, as receptors in cell-cell recognition, which can be exploited by viruses and other pathogens, and also by regulating signaling proteins, such as the epidermal growth factor receptor (EGFR) and the vascular endothelial growth factor receptor (VEGFR), through lateral interaction in the membrane. (frontiersin.org)
  • The large structural variability is related to developmental stage and cell type, and hundreds of gangliosides are known today ( 3 - 5 ). (frontiersin.org)