Cell CycleCell Cycle ProteinsCheckpoint Kinase 2Cell Cycle CheckpointsMitosisDNA DamageM Phase Cell Cycle CheckpointsGenes, cdcG2 PhaseProtein-Serine-Threonine KinasesCell Line, TumorS PhaseApoptosisCell ProliferationG2 Phase Cell Cycle CheckpointsBreast NeoplasmsG1 PhaseGene Expression Regulation, NeoplasticCell DivisionTumor Cells, CulturedPhosphorylationProtein KinasesAntineoplastic AgentsTumor Suppressor Protein p53Spindle ApparatusSignal TransductionNuclear ProteinsDNA-Binding ProteinsRNA, Small InterferingMutationAtaxia Telangiectasia Mutated ProteinsDNA ReplicationCell SurvivalNeoplasmsColonic NeoplasmsMice, NudeS Phase Cell Cycle CheckpointsTumor Suppressor ProteinsBlotting, WesternCyclinsCyclin-Dependent Kinase Inhibitor p21KinetochoresRNA, MessengerNeoplasm InvasivenessLung NeoplasmsHydroxyureaCDC2 Protein KinaseNeoplasm ProteinsFlow CytometryOvarian NeoplasmsHeLa CellsRNA InterferenceDNA RepairSaccharomyces cerevisiae ProteinsDown-RegulationCell LineReverse Transcriptase Polymerase Chain ReactionMolecular Sequence DataDrug Resistance, NeoplasmCyclin BTransfectionModels, BiologicalHCT116 CellsG1 Phase Cell Cycle CheckpointsSchizosaccharomycescdc25 PhosphatasesNocodazolePancreatic NeoplasmsSchizosaccharomyces pombe ProteinsSaccharomyces cerevisiaeXenograft Model Antitumor AssaysRetinoblastoma ProteinNeoplasm MetastasisStomach NeoplasmsTranscription FactorsEarly Detection of CancerDrug Screening Assays, AntitumorGene Expression ProfilingCell NucleusCyclin-Dependent Kinase Inhibitor p27Antineoplastic Agents, PhytogenicProtein BindingCyclin B1Cyclin D1Base SequenceCell MovementTranscription, GeneticTime FactorsCdc20 ProteinsPromoter Regions, GeneticCyclin-Dependent Kinase 2Intracellular Signaling Peptides and ProteinsCell Transformation, NeoplasticCell Growth ProcessesChromosome SegregationDose-Response Relationship, DrugEnzyme InhibitorsAmino Acid SequenceGene SilencingEnzyme Activation