Cell CycleCell ProliferationCell Line, TumorCell DivisionTumor Cells, CulturedApoptosisGene Expression Regulation, NeoplasticBreast NeoplasmsCell Cycle ProteinsSignal TransductionMice, NudeRNA, Small InterferingCell SurvivalCell Growth ProcessesAntineoplastic AgentsNeoplasmsRNA, MessengerBlotting, WesternColonic NeoplasmsReverse Transcriptase Polymerase Chain ReactionCell MovementCell Cycle CheckpointsTumor Suppressor Protein p53Down-RegulationNeoplasm InvasivenessPhosphorylationXenograft Model Antitumor AssaysTransfectionCells, CulturedRNA InterferenceNeoplasm ProteinsTumor Markers, BiologicalCell LineImmunohistochemistryPancreatic NeoplasmsTumor BurdenFlow CytometryOvarian NeoplasmsNeoplasm MetastasisLung NeoplasmsCyclin D1G1 PhaseTransplantation, HeterologousNeoplasm TransplantationTumor Suppressor ProteinsProstatic NeoplasmsDose-Response Relationship, DrugCell Transformation, NeoplasticAdenocarcinomaCyclin-Dependent Kinase Inhibitor p21Gene Knockdown TechniquesMice, Inbred BALB CProto-Oncogene Proteins c-aktUp-RegulationMolecular Sequence DataTranscription FactorsNeovascularization, PathologicMutationCell DifferentiationTime FactorsS PhaseStomach NeoplasmsCyclin-Dependent Kinase Inhibitor p27Gene Expression ProfilingGene ExpressionBase SequenceNeoplasms, ExperimentalHCT116 CellsProtein-Serine-Threonine KinasesPromoter Regions, GeneticDNA-Binding ProteinsHT29 CellsDrug Screening Assays, AntitumorMice, SCIDGenes, Tumor SuppressorCyclinsModels, BiologicalTranscription, GeneticDrug Resistance, NeoplasmMice, Inbred C57BLGene SilencingMitosisG1 Phase Cell Cycle CheckpointsEnzyme InhibitorsMCF-7 CellsRetinoblastoma ProteinMammary Neoplasms, ExperimentalDNA, NeoplasmProto-Oncogene ProteinsEnzyme ActivationKi-67 AntigenDrug SynergismMicroRNAsTumor Necrosis Factor-alphaG2 PhaseProtein BindingNuclear ProteinsGene Expression RegulationFibroblastsCell Nucleus