Bone NeoplasmsOsteolysisProstatic NeoplasmsBone and BonesOsteoclastsNeoplasm MetastasisDiphosphonatesRANK LigandCell Line, TumorOsteoprotegerinBone ResorptionBreast NeoplasmsParathyroid Hormone-Related ProteinOsteoblastsMice, NudeBone Density Conservation AgentsMice, SCIDXenograft Model Antitumor AssaysImidazolesGene Expression Regulation, NeoplasticBone RemodelingLymphatic MetastasisCulture Media, ConditionedLung NeoplasmsBone DensityNeoplasm InvasivenessBone MarrowBone DiseasesMammary Neoplasms, ExperimentalAntineoplastic AgentsLiver NeoplasmsPrognosisTumor Markers, BiologicalImmunohistochemistryBone DevelopmentBone Marrow CellsNeoplasm TransplantationCell ProliferationStrontium RadioisotopesRetrospective StudiesAdenocarcinomaNeoplasm StagingDisease ProgressionTumor Cells, CulturedSamariumCarcinomaRadiumPalliative CareSurvival AnalysisStomach NeoplasmsTechnetium Tc 99m MedronateEarly Detection of CancerNeoplasmsAlkaline PhosphataseSpinal NeoplasmsSurvival RateTomography, X-Ray ComputedCell MovementSignal TransductionTreatment OutcomeColonic NeoplasmsNeoplasm ProteinsTransplantation, HeterologousMelanomaColorectal NeoplasmsNeoplasm Recurrence, LocalReverse Transcriptase Polymerase Chain ReactionFollow-Up StudiesBone RegenerationPancreatic NeoplasmsCombined Modality TherapyKidney NeoplasmsCollagen Type IEtidronic AcidAntineoplastic Combined Chemotherapy ProtocolsOvarian NeoplasmsProstate-Specific AntigenRadiopharmaceuticalsFractures, BoneTumor BurdenBone MatrixClodronic AcidNeovascularization, PathologicCarcinoma, Squamous CellMice, Inbred BALB CHypercalcemiaDisease-Free SurvivalBone Marrow TransplantationBrain NeoplasmsSensitivity and SpecificityBone TransplantationPositron-Emission TomographyRNA, MessengerGene Expression ProfilingThyroid NeoplasmsRheniumKaplan-Meier EstimateBone Marrow NeoplasmsTime FactorsProspective Studies