Myelodysplastic SyndromesMyeloproliferative DisordersBone MarrowJanus Kinase 2Primary MyelofibrosisMyelodysplastic-Myeloproliferative DiseasesPolycythemia VeraThrombocythemia, EssentialBone Marrow CellsAnemia, RefractoryBone Marrow NeoplasmsBone NeoplasmsLeukemia, Myelomonocytic, ChronicBone Marrow TransplantationReceptors, ThrombopoietinAnemia, Refractory, with Excess of BlastsBone and BonesLeukemia, Myeloid, AcuteThrombocytosisSyndromeBone Marrow DiseasesLeukemia, MyeloidHematopoietic Stem CellsLeukemia, Myeloid, Chronic, Atypical, BCR-ABL NegativeMutationAnemia, SideroblasticLeukemia, Myelomonocytic, JuvenileOsteolysisBone Marrow ExaminationChromosomes, Human, Pair 5LeukemiaHematologic NeoplasmsPrognosisProstatic NeoplasmsSplenomegalyLeukemia, Myelogenous, Chronic, BCR-ABL PositiveProto-Oncogene Proteins c-cblOsteoclastsAzacitidineKaryotypingHematopoiesisChromosome AberrationsBlast CrisisAnemia, AplasticPhiladelphia ChromosomeBone RemodelingBone ResorptionMegakaryocytesTreatment OutcomePreleukemiaMyeloid Progenitor CellsAntineoplastic AgentsCell Line, TumorHematologyPancytopeniaTransplantation, HomologousMonosomyDisease ProgressionCell ProliferationDNA Mutational AnalysisCell Transformation, NeoplasticOsteoblastsJanus KinasesHematopoietic Stem Cell TransplantationThalidomideAntigens, CD34Mice, Inbred C57BLColony-Forming Units AssaySTAT5 Transcription FactorAcute DiseaseChromosomes, Human, Pair 7Megakaryocyte Progenitor CellsFlow CytometryNeoplasms, Second PrimaryNeoplasmsBreast NeoplasmsBone DensityMegakaryocyte-Erythroid Progenitor CellsGranulocytesSurvival AnalysisMyelopoiesisNeoplasm MetastasisCytogenetic AnalysisMutation, MissenseCell DifferentiationRANK LigandSignal TransductionOsteoprotegerinClonal EvolutionChromosome DeletionSurvival RateFusion Proteins, bcr-ablRetrospective StudiesBlood Cell CountPhenotypeGranulocyte Precursor CellsProto-Oncogene ProteinsProtein Kinase InhibitorsMice, SCIDPolymerase Chain Reaction