ras Guanine Nucleotide Exchange FactorsSon of Sevenless Proteinsras-GRF1Guanine Nucleotide Exchange FactorsGuanineras ProteinsGRB2 Adaptor ProteinAmino Acid MotifsGenes, rasGuanine NucleotidesMolecular Sequence DataProto-Oncogene Proteins p21(ras)Amino Acid SequenceCyclic AMPOncogene Protein p21(ras)Protein BindingBase SequenceGuanosine TriphosphateKineticsGuanosine DiphosphateGuanine DeaminaseRho Guanine Nucleotide Exchange FactorsGTP-Binding ProteinsProtein Structure, TertiaryMutationModels, Molecularras GTPase-Activating ProteinsBinding SitesSignal TransductionCell LineNucleotide MotifsSequence Homology, Amino AcidDNADeuterium Exchange MeasurementPulmonary Gas ExchangeAdenylate CyclaseExchange Transfusion, Whole BloodRecombinant ProteinsCyclic AMP-Dependent Protein KinasesSister Chromatid ExchangeRecombinant Fusion ProteinsEscherichia coliCells, CulturedEnzyme ActivationTransfectionCloning, MolecularPhosphorylationProteinsMutagenesis, Site-DirectedDNA-Binding ProteinsCarrier ProteinsSequence AlignmentGTP PhosphohydrolasesColforsinGuanosine 5'-O-(3-Thiotriphosphate)Transcription FactorsConserved SequenceGTPase-Activating ProteinsThionucleotidesCell MembranePromoter Regions, GeneticStructure-Activity RelationshipCrystallography, X-RayModels, Biologicalrap GTP-Binding ProteinsCalciumTranscription, GeneticNucleic Acid Conformationral Guanine Nucleotide Exchange FactorGuanylyl ImidodiphosphateProto-Oncogene Proteins c-rafProtein Structure, SecondaryCOS CellsSubstrate SpecificityProtein ConformationMembrane ProteinsSaccharomyces cerevisiaerap1 GTP-Binding ProteinsMagnetic Resonance SpectroscopyProtein Interaction Domains and MotifsBacterial ProteinsRNA, MessengerHydrogenChromatography, Ion ExchangeHydrogen-Ion ConcentrationGuanine Nucleotide Dissociation InhibitorsADP-Ribosylation FactorsGuanosinePeptides3T3 CellsProto-Oncogene Proteins c-vavAdenosine TriphosphateHeLa CellsGuanine Nucleotide-Releasing Factor 2Sodium-Hydrogen AntiporterBinding, CompetitiveAdeninecdc42 GTP-Binding ProteinDNA PrimersMutagenesis