• The Calyx of Held is a particularly large synapse in the mammalian auditory central nervous system, so named after Hans Held who first described it in his 1893 article Die centrale Gehörleitung because of its resemblance to the calyx of a flower. (wikipedia.org)
  • Globular bushy cells in the anteroventral cochlear nucleus (AVCN) send axons to the contralateral medial nucleus of the trapezoid body (MNTB), where they synapse via these calyces on MNTB principal cells. (wikipedia.org)
  • The related endbulb of Held is also a large axon terminal smaller synapse (15-30 μm in diameter) found in other auditory brainstem structures, namely the cochlear nucleus. (wikipedia.org)
  • Commonly used in research due to its large size, the calyx of Held has been used to understand a variety of mechanisms related to development of, and vesicle release of the synapse. (wikipedia.org)
  • As a synapse, the function of the calyx of Held is to transmit the signal from the GBCs to the principal neurons. (wikipedia.org)
  • Here the role of glutamatergic transmission at the calyx synapse is investigated. (jneurosci.org)
  • It is highly likely that the peculiar morphology of the hair cell/calyx synapse has consequences for synaptic transmission. (jneurosci.org)
  • Motivated by the need to address some aspects of the functioning of neural synapses, we have developed one such model for synaptic processes in the calyx of Held , which is a glutamatergic synapse in the auditory pathway of the mammalia. (biomedcentral.com)
  • 682. Reliability and precision of the mouse calyx of Held synapse. (neuro.nl)
  • The CMSF unit used rat brain slices to study a giant synapse called the calyx of Held. (oist.jp)
  • The large size of the calyx of Held allows scientists to visualize and manipulate the synapse. (oist.jp)
  • Flowers of polemonium pulcherrimum consist of a green, sparsely glandular hairy calyx divided about half its length into five triangular lobes, and a white or bluish-purple, bell-shaped corolla with five spreading, rounded lobes. (americansouthwest.net)
  • The hairy calyx has 5 triangular lobes. (minnesotawildflowers.info)
  • For every principal neuron there is one calyx, and for most GBC axons there is only a single calyx, although there are exceptions to this pairing. (wikipedia.org)
  • Dark stems hold rosy pink calyxes and white flowers. (provenwinners.com)
  • Late autumn replaces blooms with small rounded purplish fruits surrounded by luxe long-lasting rosy-pink calyces. (diggingdog.com)
  • We have shown that formation of synaptic contact between the calyx of Held, perhaps the largest nerve terminal in the CNS, and its postsynaptic partner passes through a competitive phase during rapid growth over only a few days. (hhs.gov)
  • Preliminary data suggest novel modes of physical interaction between growing calyces and glia in the developing brain and observed synaptic input onto glial cells at early neonatal ages. (hhs.gov)
  • This unique data set, coupled to our novel whole-head slice preparation and genetic and viral vector tools developed during the last grant period, anchors investigations of the onset of neural activity from embryonic ages, roles for neural activity in calyx growth and competition, and potential synaptic communication among neurons and glia during neural circuit maturation. (hhs.gov)
  • The calyx of Held holds vesicles containing glutamate on the presynaptic terminal, the vesicles are released upon stimulation (originating in the auditory system). (wikipedia.org)
  • The calyx of Held is a part of the auditory system, connecting the globular bushy cells (GBCs) of the anteroventral cochlear nucleus to the principal neurons of the medial nucleus of the trapezoid body (MNTB). (wikipedia.org)
  • The foliage is a rich hue, and holds onto its purple color for much of the season. (provenwinners.com)
  • Flowers are held on dark calyxes forming vertical spires above the dark green foliage. (bluestoneperennials.com)
  • Compared to 'Blackberry Ice', the foliage is larger, a richer hue, and holds onto its purple color for much of the season. (bloomindesigns.com)
  • Petals are held horizontally and overlap for maximum display. (perennialresource.com)
  • 4½" fuchsia pink flowers are made of overlapping, horizontally held petals for an exceptionally showy display. (perennialresource.com)
  • The ‌ sepals ‌, together called the ‌ calyx ‌, are the smaller, usually green, petals around the base of the flower. (gardenguides.com)
  • Outermost petals are boldly striped with green as if each huge bloom is held in a rose-like calyx. (bowoodfarms.com)
  • The plant produces fragrant flowers on branching peduncles, with white petals held within a green calyx that turns red as the fruits ripen. (sheffields.com)
  • Established in 1988 as Calyx & Corolla, today Calyx Flowers provides premium luxury flowers, plants and gifts for flower lovers across the country. (calyxflowers.com)
  • The center of the flower is yellow, as is the short corolla tube, which is mostly hidden by the calyx. (americansouthwest.net)
  • The calyx of Held encompasses the principal neuron with a distinct morphology: branching of the calyx allows the creation of second- and third-order networks. (wikipedia.org)
  • At postnatal day two (P2), the immature rat calyx of Held is formed, easily distinguished by its characteristic sealed-spoon morphology. (wikipedia.org)
  • Flowers cover the top two thirds of these plants from mid to late summer, with colorful calyxes extending interest well into fall. (perennialresource.com)
  • Hold berries by their stem or calyx (green leaves) and dip in bowl of melted chocolate, swirling until coated as much as you like. (cooksrecipes.com)
  • Whether grown as a shrub or trained as a tree, its flaring tubular white flowers and striking bright blue berries in a reddish calyx make it a fantastic addition to any garden or landscape. (sheffields.com)
  • Calyx ¼", Yellow Green Group 144A. (vt.edu)
  • Calyx ⅛" Yellow Green Group 151B. (vt.edu)
  • Calyx ¼- 3 / 16 ", Green Group 142C. (vt.edu)
  • Calyx 1 / 16 ", green edged red. (vt.edu)
  • As a result of its role in stimulating the principal neurons, the primary function of the calyx of Held is to allow differentiation between temporal activation of the cochlear hair cells that are important in sound localization (interaural level detection). (wikipedia.org)
  • Interaural level detection is possible through the calyx system due to the large relative size of the GBCs, the calyx of Held, and the principal neurons. (wikipedia.org)
  • This in general creates a one-to-one ratio between GBCs, the calyces of Held, and the principal neurons. (wikipedia.org)
  • As with the calyces, these synapses promote fast, efficient information transfer. (wikipedia.org)
  • In the vestibular periphery a unique postsynaptic terminal, the calyx, completely covers the basolateral walls of type I hair cells and receives input from multiple ribbon synapses. (jneurosci.org)
  • Yamashita found that the anesthetic affected cortico-cortical synapses in a similar way to the calyx of Held. (oist.jp)
  • leaves held well through winter. (vt.edu)
  • Flowers are produced in small numbers (typically four or five) at the top of the stems, attached by short stalks, and held a little way above the uppermost leaves. (americansouthwest.net)
  • Since businesses like Calyx typically sell to a variety of CROs, separating from Paraxel made sense - though carveout costs may have temporarily impacted Calyx's financials, sources say. (axios.com)
  • Isis standing facing, looking right or left, holding sistrum in right hand and a disc-shaped object or dish of fruit (sometimes with snake) in left. (tesorillo.com)
  • Isis standing facing, looking right, holding branch and dish of fruit. (tesorillo.com)
  • Fill vase ¾ full with warm water and add Calyx floral preservative. (calyxflowers.com)
  • Early autumn brings the showy fragrant floral display, for which the species is named: 6 jasmine-like milky-white blooms held in tiered whorls on branch tips. (diggingdog.com)
  • The calyx has a large number of microtubules at the base of the terminal. (wikipedia.org)
  • Large saturated hot pink flowers held on deep chocolate-black calyx and stems. (planthaven.com)
  • Masses of large saturated hot pink flowers held on striking deep chocolate-black calyx and stems, freely reflowering throughout the season. (planthaven.com)
  • Isis as sea-goddess, reclining left, holding a large cornucopia with both hands, resting left arm on an overturned urn, out of which flows water. (tesorillo.com)
  • early throat deep pink 10RP 6/12, lobe edges diffused strong purplish red 10RP 5/12, reverse deep pink 10RP 6/12 to strong pink 10RP 7/8 Calyx ¼", white. (vt.edu)
  • Comparing the predictions of the model with previously measured release probabilities under a variety of experimental conditions, we inferred which release site topography is likely to operate at the calyx: At each AZ one or a few clusters of Ca2+ channels control the release of the vesicles. (mpg.de)
  • Previously a subsidiary of CRO Parexel, Calyx split from the company in January 2021 and became a separate, independent company. (axios.com)
  • The parameters of the model were constrained by recent anatomical and biophysical data of the calyx of Held. (mpg.de)
  • Anubis accompanies the carriage, looking back and holding palm branch in right hand. (tesorillo.com)
  • The spherical flowerheads of globe thistles are pleasing to the eye, and produce smooth brown seeds held inside each calyx, that are easily picked off by finches. (gardenersworld.com)
  • Calyx sits smack in the middle of a hot sector experiencing strong tailwinds and commanding tons of private equity interest. (axios.com)
  • Calyx Token (CLX) offers a kind of unique investment platform for all venture capitalists that want to extend their cryptocurrency portfolio. (ethozedge.com)
  • The Calyx Token (CLX) team has gone on to build a very unique protocol that lets its users access better, quicker, and cheaper transfers between tokens. (ethozedge.com)
  • So many people believe that Calyx Token's (CLX) unique protocol gives it the chance to move into the top 100 cryptos as early as 2025. (ethozedge.com)
  • Calyx Token is becoming a huge cryptocurrency treasure. (ethozedge.com)
  • Their deep throats hold plenty of nectar for your favorite winged creatures all season long. (provenwinners.com)
  • We propose that similar to other brain areas, such as the cerebellum and hippocampus, glutamate spillover may play a role in gain control of calyx afferents and contribute to their high-pass properties. (jneurosci.org)
  • Calyx krater depicting a female figure adorning a herm with an altar in front of it and a nude man holding a spit for entrails from a sacrifice. (eveandersson.com)
  • Serapis standing front, looking right or left, raising right hand and holding globe in left hand. (tesorillo.com)
  • Calyx has been transitioning out of an ownership structure where it was arguably under-loved and under-invested, consistent with its financial profile. (axios.com)
  • Calyx DeRoche produced this profile of the Black Urban Gardeners and Farmers, a farm and food advocacy group located in Pittsburgh's Homewood neighborhood. (wqed.org)
  • Calyx Token (CLX) network currently supports ETH with the potential to support more, including MATIC, BNB, and AVAX. (ethozedge.com)
  • The ‌ receptacle ‌ is the structure that holds the sepals. (gardenguides.com)
  • Trim ½" from the bottom of bouquet while holding stems under water, and place immediately in vase. (calyxflowers.com)
  • Isis, holding sistrum in raised right hand and reins in left, standing in a cart drawn to left by two mules. (tesorillo.com)
  • River-god Nile reclining left, in a cart drawn right by two hippopotamus, holding in right hand a cornucopia . (tesorillo.com)