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Calcium SignalingCalcium ChannelsCalciumCalcium, DietaryCalcium ChlorideIon ChannelsCalcium CarbonateCalcium IsotopesCalcium PhosphatesEgtazic AcidCalcium GluconateMagnesiumCalcium Channels, L-TypeIon TransportCalcium RadioisotopesKineticsIon Channel GatingChelating AgentsCalcium OxalateMembrane PotentialsPotassiumCalcimycinCalcium CompoundsStrontiumHydrogen-Ion ConcentrationSodiumLanthanumEdetic AcidFura-2AequorinCalcium-Binding ProteinsIonsCalcium Channels, N-TypeCells, CulturedAdenosine TriphosphateMolecular Sequence DataAmino Acid SequenceBinding SitesHeavy IonsCations, DivalentVerapamilTime FactorsCalmodulinRabbitsNifedipineCalcium Channel AgonistsCytosolProtein BindingDose-Response Relationship, DrugFluorescent DyesPatch-Clamp TechniquesIntracellular FluidModels, MolecularElectrophysiologyParathyroid HormoneCattleThapsigarginCell Membrane PermeabilityNeuronsProtein ConformationS100 Calcium Binding Protein GPhosphorusBuffersCalcium HydroxideElectric ConductivityBiological Transport, ActiveCationsMusclesRyanodine Receptor Calcium Release ChannelArsenazo IIICalcium SulfateModels, BiologicalDiltiazemManganeseInositol 1,4,5-TrisphosphateIonophoresIonomycinZincOsmolar ConcentrationChloridesCaffeineOxalatesBiological TransportCell LinePotassium ChlorideTemperatureSignal TransductionCalcium CitrateMuscle ContractionEthersInositol 1,4,5-Trisphosphate ReceptorsHomeostasisMetalsMyocardiumElectric StimulationSpectrometry, FluorescenceEnzyme ActivationProtein Structure, TertiaryReceptors, Calcium-SensingRats, Sprague-Dawley
Intracellular Calcium IonConcentrationChloridePotassiumSodiumElectrodesBariumSaltsBindsProteinsBicarbonateCations2023SecretionVoltage-dependent calcium channelsTissuesBlood PlateletsHomeostasisZincMembraneMetal ionElectrodeConductionFluorideSerumChannelsProteinCellularCyclicReactionStainsAnionsSulfateNanoparticlesAnionicSelectiveCardiomyocytePoreAqueousBlendsElectronMolecularRegulatesAlbuminMediatesProcessesExcitationMeasurementSubstancesContent
Intracellular Calcium Ion1
  • Monitoring Intracellular Calcium Ion Dynamics in Hair Cell Populations with Fluo-4 AM" PLOS ONE Vol. 7 Iss. (bepress.com)
Concentration11
  • The ISA ensures that the activity coefficient is constant so the concentration of free calcium ions can be measured. (hannaservice.si)
  • When the ionic strength of the solution is fixed by the addition of ISA, the voltage is proportional to the concentration of free ions in solution. (hannaservice.si)
  • The Ammonium Ion-Selective Electrode (ISE) can be used to measure the concentration of Ammonium (NH 4 + ) in aqueous samples. (vernier.com)
  • Our results show that the concentration of free cations in the electrolyte is primarily coordinated with NMP as well as PVDF, generating a suitable network for ion transport, i.e., a liquid electrolyte encompassed within a polymer matrix. (syr.edu)
  • Link to all annotated objects annotated to regulation of cytosolic calcium ion concentration. (planteome.org)
  • Link to all direct and indirect annotations to regulation of cytosolic calcium ion concentration. (planteome.org)
  • The concentration of calcium (Ca2+ ions) is normally several thousand times higher outside the cell than inside. (wikipedia.org)
  • The best optode tested exhibited a good response to calcium ions in the concentration range from 10 -7 M to 10 -1 M with 0.05 M Tris-HCl of pH 7.0 as the flowing buffer solution. (elsevierpure.com)
  • Sensor response theory, response time, selectivity, and application to the determination of calcium ion concentration in human serum were also discussed together with experimental results. (elsevierpure.com)
  • The total calcium concentration in the plasma is 4.5-5.1 mEq/L (9-10.2 mg/dL). (medscape.com)
  • Clinical signs and symptoms are observed only with decreases in ionized calcium concentration (normally 4.5-5.5 mg/dL). (medscape.com)
Chloride5
Potassium3
  • The potassium and calcium salts of oxalic acid are found naturally in cabbage, spinach , and rhubarb leaves, and are also found in the bark of some species of eucalyptus trees. (jrank.org)
  • Activation of particular VGCCs allows a Ca2+ influx into the cell, which, depending on the cell type, results in activation of calcium-sensitive potassium channels, muscular contraction, excitation of neurons, up-regulation of gene expression, or release of hormones or neurotransmitters. (wikipedia.org)
  • The ion channels affected include those responsible for the inward sodium or calcium currents and those responsible for the outward potassium current. (msdmanuals.com)
Sodium4
Electrodes2
Barium1
Salts2
  • Calcium salts of different acids varied in their effects on water soaking. (uni-hannover.de)
  • Notably, Chelated PolyAspartic Acid with Calcium and Zinc Salts exhibits remarkable characteristics due to its peptide bond structure, active groups like carboxyl, and natural biodegradable nature. (marknature.com)
Binds4
  • SdrD binds calcium ions using its B1-B5 region bearing EF-hand Ca-binding sites, leading to conformational changes in the structure of SdrD. (hal.science)
  • Fifty percent of plasma calcium is ionized, 40% is bound to proteins (90% of which binds to albumin), and 10% circulates bound to anions (eg, phosphate, carbonate, citrate, lactate, sulfate). (medscape.com)
  • At a plasma pH of 7.4, each gram of albumin binds 0.8 mg/dL of calcium. (medscape.com)
  • Ionized calcium binds to negatively charged sites on protein molecules, competing with hydrogen ions for the same binding sites on albumin and other calcium-binding proteins. (medscape.com)
Proteins2
  • Several EF-hand containing calcium-binding proteins (CaBPs) have been identified from E. histolytica. (rcsb.org)
  • In the following, we refer to pump of halophilic archaebacteria, has become the these as the extracellular (EC) channel and the paradigm of membrane proteins in general and ion cytoplasmic (CP) channel. (lu.se)
Bicarbonate1
  • Calcium carbonate reacts with water that is saturated with carbon dioxide to form the soluble calcium bicarbonate . (wikipedia.org)
Cations1
20231
  • 2023. Interaction Profile for Selected Metallic Ions (Draft for Public Comment). (cdc.gov)
Secretion3
  • The effects of strontium and calcium ions on 5-hydroxytryptamine secretion and thromboxane B2 biosynthesis in washed human platelets. (ox.ac.uk)
  • Calcium is necessary for bone mineralization and is an important cofactor for hormonal secretion in endocrine organs. (medscape.com)
  • Calcium is essential for bone mineralization, neuromuscular function, and secretion of hormones and enzymes. (medscape.com)
Voltage-dependent calcium channels1
Tissues1
  • The fluoride ion, which penetrates tissues deeply, can cause both local cellular destruction and systemic toxicity and is readily absorbed through both intact and damaged skin. (cdc.gov)
Blood Platelets1
  • Measurement of Ionized Calcium in Blood Platelets with a New Generation Calcium Indicator E Biochem Biophys Res Commun. (dojindo.com)
Homeostasis1
Zinc1
Membrane6
  • The HI4104 is a liquid membrane, calcium combination ion selective electrode (ISE) for the determination of calcium (Ca2+) in solution. (hannaservice.si)
  • The PVC membrane comprised with organic ion exchanger produces a potential change due to the calcium ion exchange between the organic polymer membrane and the sample. (hannaservice.si)
  • The HI4104 calcium liquid membrane ISE can measure from 3µM (0.12 mg/L) to 1M (40,080 mg/L). (hannaservice.si)
  • A liquid membrane ion selective electrode develops a voltage due to the ion exchange that occurs between the solution and the polymer membrane that contains organic ion exchange resin. (hannaservice.si)
  • At the cellular level, calcium is an important regulator of ion transport and membrane integrity. (medscape.com)
  • Voltage-dependent cell membrane glycoproteins selectively permeable to calcium ions. (bvsalud.org)
Metal ion3
  • Using a solution that includes a free metal ion (e.g. calcium) and a chelating agent solution (EDTA) this titanium transfer is measured against a normal Ca2 + ion solution. (ukessays.com)
  • Metal Ion Chelation of PolyAspartic A. (marknature.com)
  • The observations indicate that the crosslinking is diffusion controlled and is affected by the size of metal ion and the type of alginate used. (amrita.edu)
Electrode1
  • Fill-up your electrode with correct and fresh electrolyte for a precise ion determination. (scalesgalore.com)
Conduction2
  • We report a gel polymer electrolyte (GPE)-based on polyvinylidene fluoride (PVDF) for calcium ion conduction. (syr.edu)
  • In the neuromuscular system, ionized calcium facilitates nerve conduction, muscle contraction, and muscle relaxation. (medscape.com)
Fluoride1
  • Its severe and sometimes delayed health effects are due to deep tissue penetration by the fluoride ion. (cdc.gov)
Serum5
Channels11
  • Is the Subject Area "Calcium channels" applicable to this article? (plos.org)
  • This review summarizes the recent knowledge underlying this paradoxical nociception, with a focus on the ion channels involved in tooth pain. (mdpi.com)
  • The expression of temperature-sensitive ion channels has been extensively investigated because thermal stimulation often evokes tooth pain. (mdpi.com)
  • Voltage-gated calcium channels are formed as a complex of several different subunits: α1, α2δ, β1-4, and γ. (wikipedia.org)
  • There are several different kinds of high-voltage-gated calcium channels (HVGCCs). (wikipedia.org)
  • Researchers in Prof. Özkale Edelmann's team used kidney cells to demonstrate that cellular ion channels can be influenced. (nanowerk.com)
  • The team observed that the ion channels of the cells opened at certain temperatures, for example to allow calcium to enter the cell. (nanowerk.com)
  • Partly because bestrophin channels have no sequence or structural similarity to other ion channels, the molecular mechanisms underlying gating are unknown. (elifesciences.org)
  • The studies define a new molecular paradigm for gating among ligand-gated ion channels. (elifesciences.org)
  • Cardiomyocyte model of mechanical modulation of ion channels and calcium handling. (ox.ac.uk)
  • Either gain of function or loss of function in these ion channels, particularly when the abnormal channels are unevenly distributed, fosters abnormal electrophysiological environments. (msdmanuals.com)
Protein4
  • J Biol Chem 2004;279:12898-12908) The crystal structure of the Entamoeba histolytica calcium binding protein-1 (EhCaBP1) has been determined at 2.4 A resolution. (rcsb.org)
  • These nanoparticles consisted of a nutraceutical -loaded protein core ( curcumin -loaded zein nanoparticles ) and a gelled polysaccharide shell ( calcium cross-linked ι- carrageenan ). (bvsalud.org)
  • An increase in pH, alkalosis, promotes increased protein binding, which decreases free calcium levels. (medscape.com)
  • Acidosis, on the other hand, decreases protein binding, resulting in increased free calcium levels. (medscape.com)
Cellular2
  • cADPtR is the first stable equivalent of cADPR that is as active as cADPR in various cellular systems, making it useful for investigating Ca ion-release signaling pathways. (bath.ac.uk)
  • Excessive activation of VGCCs is a major component of excitotoxicity, as severely elevated levels of intracellular calcium activates enzymes which, at high enough levels, can degrade essential cellular structures. (wikipedia.org)
Cyclic1
  • We previously reported the involvement of nitric oxide (NO) and cyclic nucleotide-gated ion channel 6 (CNGC6) in the responses of plants to heat shock (HS) exposure. (biomedcentral.com)
Reaction1
Stains2
  • It is a white solid used in removal of certain kinds of stains, in removing calcium ions from solutions, and in tanning leather. (jrank.org)
  • To study the effect of tap water `softening' (i.e. calcium extraction) on H&E stains, 5 sets of slides from 30 different paraffin-embedded human pathologic tissue blocks were prepared in the same way except for washing with 5 different types of water. (who.int)
Anions2
  • Ions with a negative charge are called anions. (medlineplus.gov)
  • Approximately 15% is complexed calcium bound to organic and inorganic anions, 40% is bound to albumin, and the remaining 45% circulates as free ionized calcium. (medscape.com)
Sulfate1
  • We hereby introduce anionic siRNA nanoparticles (NPs) co-assembled by the electrostatic interactions of the semi-synthetic polysaccharide hyaluronan-sulfate (HAS), with siRNA, mediated by calcium ion bridges. (bgu.ac.il)
Nanoparticles2
  • Calcium ions induced ι-carrageenan-based gel-coating deposited on zein nanoparticles for encapsulating the curcumin. (bvsalud.org)
  • In summary, calcium carrageenan -coated zein nanoparticles have potential for the encapsulation, protection , and controlled release of hydrophobic nutrients . (bvsalud.org)
Anionic1
  • Cation sensing material was prepared by coating pellicular-type ODS (octadecylsilica) beads with a lipophilic organic liquid which incorporates a novel neutral calcium ionophore and a lipophilic anionic dye of the diphenyl amine type. (elsevierpure.com)
Selective1
  • The novel calcium ion selective neutral ionophores designed and synthesized were double-armed diazacrown ether compounds possessing glycolic amides as the binding arms. (elsevierpure.com)
Cardiomyocyte2
  • Channelopathies are a group of genetic, autoimmune, or inflammatory conditions that alter cardiomyocyte ion channel function in a manner that predisposes to bradyarrhythmias or tachyarrhythmias in the absence of a structural heart disorder. (msdmanuals.com)
  • and inflammatory disorders producing cytokinins that affect cardiomyocyte ion channel function are increasingly being recognized. (msdmanuals.com)
Pore2
  • The α1 subunit forms the ion-conducting pore while the associated subunits have several functions including modulation of gating. (wikipedia.org)
  • The channel comprises five BEST1 subunits arranged symmetrically around a central ion pore that is ~95 Å long. (elifesciences.org)
Aqueous1
  • The improved swelling time for crosslinked blends in aqueous medium supports the fact that the stability under physiological conditions of the blends is improved due to crosslinking with the metal ions. (amrita.edu)
Blends1
  • Calcium ion crosslinked blends can be considered suitable for biomedical drug applications. (amrita.edu)
Electron2
  • Understanding Calcium Ion Electron Configuration: A Comprehensive Guide Introduction Have you ever wondered about the electron configuration of calcium ions? (applechon.com)
  • This guide will examine all aspects of calcium ion electron configuration to help you better understand this critical topic. (applechon.com)
Molecular1
  • This allowed us to propose a model of B1-B5 reorganization upon binding of calcium and to get new insight into the molecular mechanism of SdrD's action. (hal.science)
Regulates2
Albumin1
  • Acute acidemia decreases calcium binding to albumin, whereas alkalemia increases binding, which decreases ionized calcium. (medscape.com)
Mediates1
  • PTH stimulates osteoclastic bone reabsorption and distal tubular calcium reabsorption and mediates 1,25-dihydroxyvitamin D (1,25[OH] 2 D) intestinal calcium absorption. (medscape.com)
Processes2
  • In many industrial processes oxalic acid is used to remove calcium ions from solutions. (jrank.org)
  • Ionized calcium is the necessary plasma fraction for normal physiologic processes. (medscape.com)
Excitation1
  • 8. Monitor the excitation spectra at 380 nm (calcium free) and 340 nm (calcium complex) with fixed emission at 510 nm. (dojindo.com)
Measurement1
  • Fura 2 is one of the most widely used calcium indicators for ratiometric measurement. (dojindo.com)
Substances1
Content1
  • In this experiment, the calcium content in milk is measured by EDTA back titration. (ukessays.com)