• Though symptoms are rarely exhibited in children, early screening of children for cardiovascular diseases could be beneficial to both the child and his/her relatives. (wikipedia.org)
  • Vascular calcification (VC) is highly prevalent and increases the morbidity and mortality of cardiovascular diseases. (bvsalud.org)
  • However, lowering LDL levels is a common clinical practice to reduce oxidation and the risk of major events in patients with cardiovascular diseases (CVD). (hindawi.com)
  • Cardiovascular diseases (CVD) are the leading cause of mortality in the Western population [ 1 ]. (hindawi.com)
  • He is also designing a small diameter tissue engineered vascular graft to treat cardiovascular diseases. (pitt.edu)
  • Immune dysregulation has been identified as a critical cause of the most common types of cardiovascular diseases (CVDs). (biomedcentral.com)
  • Many types of cardiovascular diseases (CVDs) are associated with complex immune responses that can significantly contribute to their progression and remission. (biomedcentral.com)
  • Aging is the most profound risk factor for many non-communicable diseases and in itself confers a greater risk for cardiovascular disease than the traditional risk factors such as lipid levels, smoking, diabetes, hypertension and sedentary lifestyle. (jscimedcentral.com)
  • Arterial stiffening is an independent predictor of cardiovascular (CV) outcomes such as myocardial infarction, cognitive decline in aging, stroke, and kidney diseases [8]. (jscimedcentral.com)
  • Regular intake of ready-to-eat meals is related to obesity and several noninfectious illnesses, such as cardiovascular diseases, hypertension, diabetes mellitus (DM), and tumors. (diabeets.com)
  • Current studies regarding the consumption of ready-prepared foods and their consequences reliably reported a significant correlation between obesity, several noninfectious illnesses (noncommunicable diseases (NCDs)), cardiovascular diseases, hypertension, several types of malignancies, and many more [1-5] . (diabeets.com)
  • He is the principal investigator of the Cardiovascular Molecular Imaging Laboratory, which aims to develop new imaging techniques to visualize, characterize, and quantify molecular and cellular processes involved in cardiovascular diseases. (yalemedicine.org)
  • Therefore, studies investigating novel molecular mechanisms of cardiovascular diseases, preclinical translational research, and clinical management that can shed some light to this important field are welcome in this Special Issue. (mdpi.com)
  • ABSTRACT Associations of oral diseases with noncommunicable diseases such as diabetes, cardiovascular diseases, chronic respiratory diseases, osteoporosis and chronic renal failure are widely reported in the literature from developed countries. (who.int)
  • Online searches were made to find literature for the study of other tissues and organs and on oral diseases, e.g. dental caries, perio- as a potential source of pathology affecting dontal diseases and tooth loss, and on NCD, other systems and organs" [ 6 ]. (who.int)
  • Renin-angiotensin-aldosterone system gene polymorphisms and coronary artery disease: detection of gene-gene and gene-environment interactions. (cdc.gov)
  • The sirolimus-eluting Slender IDS coronary stent (Svelt Medical Systems), exquisitely skinny to simplify crossing lesions without predilatation, came up short in a randomized noninferiority trial against familiar Xience (Abbott Vascular) and Promus (Boston Scientific) drug-eluting stents (DES). (medscape.com)
  • Although coronary calcification is a marker of coronary atheroma, dense calcification (>400 HU) is usually associated with stable plaques. (clinsurgeryjournal.com)
  • In 1999 NICE examined the use of coronary stents as the first in a number of cardiovascular exercises, being followed by glycoprotein IIb/IIIa receptor blockers, and implantable defibrillators. (bmj.com)
  • Previous research have observed that coronary artery calcification is carefully related to the prevalence of important unfavorable cardiac events (MACE). (interesjournals.org)
  • Up to 40% of the US population will develop type 2 diabetes during their lifetime, and type 2 diabetes is an important contributor to major adverse cardiovascular events (MACE) such as myocardial infarction and stroke-the leading causes of morbidity and mortality in Western countries [ 2 ]. (springer.com)
  • Cardiovascular (CV) risk factors such as hypercholesterolemia, hyperglycaemia, obesity, hypertension, smoking, and aging promote vascular inflammation and endothelial activation [ 7 - 9 ]. (hindawi.com)
  • Leptin also has immune-modulatory effects and it has been suggested that this hormone links obesity with inflammation and hence with cardiovascular disease by such mechanisms [ 12 - 14 ]. (biomedcentral.com)
  • Since leptin apparently interact with many of the features of cardiovascular risk, such as blood pressure and inflammation, it might be a useful marker of prognosis that gives information that is independent of a cluster of classical clinical risk factors. (biomedcentral.com)
  • Gross calcification generally follows the fibrosis that is produced by inflammation. (raypeat.com)
  • Most of the time, patients realize that they have the disease only when they experience other cardiovascular disorders such as stroke or heart attack. (wikipedia.org)
  • The primary thrust of the lab is on cardiovascular disease-the leading global cause of death. (fiu.edu)
  • We aimed to evaluate sex differences in cardiorespiratory fitness in a relatively healthy population and its association with cardiovascular disease (CVD) events. (cardiologyonline.com)
  • AGT rs699 and AGTR1 rs5186 gene variants are associated with cardiovascular-related phenotypes in atherosclerotic peripheral arterial obstructive disease. (cdc.gov)
  • In my free time, I enjoy fitness, hiking, watching the Premier League, and reading journal articles related to cardiovascular disease. (pitthonors.blog)
  • My project studies a disorder called calcific aortic valve disease (CAVD), characterized by hardening of the heart's aortic valve due to calcification. (pitthonors.blog)
  • As the leading cause of death in this country, cardiovascular disease interests me greatly, and I am fascinated by how established preventative medicine approaches can be applied at the population level to limit the incidence of chronic heart disease. (pitthonors.blog)
  • European Guidelines on cardiovascular disease prevention in clinical practice (version 2012). (reproduct-endo.com)
  • European Cardiovascular Disease Statistics 2012. (reproduct-endo.com)
  • I am interested in many aspects of cardiovascular medicine, especially valvular heart disease, but also ischaemic heart disease, cardiomyopathies, and atrial fibrillation. (otago.ac.nz)
  • The leading cause of death in end-stage kidney disease is related to cardiovascular disease. (biomedcentral.com)
  • Even mild chronic kidney disease (CKD) with isolated albuminuria has been associated with a 2- to 4-fold increased risk of cardiovascular events [ 1 ]. (biomedcentral.com)
  • The mechanistic relationship between renal functional decline and increasing rates of cardiovascular disease and mortality is complex and not fully explained by the frequent co-existence of conventional CVD risk factors such as diabetes, hypertension or dyslipidemia [ 8 ]. (biomedcentral.com)
  • Any increase of arterial stiffness above 9 m/s, which is not correlated with chronologic age, can suggest and direct us to investigate additional comorbidities such a diabetes, hypertension or chronic renal disease that increase arterial stiffness and hence cardiovascular mortality. (jscimedcentral.com)
  • Ageing in itself confers a greater risk for cardiovascular disease than the traditional risk factors such as lipid levels, smoking, diabetes, hypertension and sedentary lifestyle [3]. (jscimedcentral.com)
  • New and clinically useful markers of cardiovascular risk are of essence in type 2 diabetes since ischemic heart disease is a major cause of death in these patients. (biomedcentral.com)
  • Except for established traditional risk markers for vascular disease, we also estimated vascular complications non-invasively by performance of carotid-femoral pulse-wave velocity (PWV, with applanation-tonometry) and intima-media thickness of carotid arteries (IMT, with B-mode ultrasound). (biomedcentral.com)
  • Our data support the use of serum leptin in type 2 diabetes to add independent prognostic information in terms of ischemic heart disease when compared with traditional cardiovascular risk factors. (biomedcentral.com)
  • In the men of the cohort this prognostic information was in addition also to data on IMT and PWV, two non-invasive measurements of the extent of vascular disease. (biomedcentral.com)
  • The power to detect a similar relationship in women was less strong due to lower incidence of cardiovascular disease. (biomedcentral.com)
  • The major cause of death in type 2 diabetes mellitus is cardiovascular disease. (biomedcentral.com)
  • Yet another non-invasive estimation of the degree of vascular disease can be done by evaluating the thickness of the intima and media of carotid arteries by ultrasound [ 2 ]. (biomedcentral.com)
  • The aim of our research is to understand the role of GPCRs, together with their transmitters in the human cardiovascular system and how these are altered with disease, in particular the consequences of endothelial cell dysfunction, to identify new targets for novel drugs. (cam.ac.uk)
  • The peptide apelin is the endogenous ligand for a novel G-protein coupled receptor with an emerging key role in cardiovascular disease. (cam.ac.uk)
  • Dr. Albers develops mathematical models of physiology, machine learning models, and their associated inference methods to support the extraction and creation of new knowledge from data related to diabetes, to support clinician-centric decision support, and to support patient-centric decision support for chronic disease self-management. (cuanschutz.edu)
  • The prevalence of cardiovascular disease (CVD) is steadily rising and is expected to increase by a minimum of 10% over the next 20 years. (biomedcentral.com)
  • Each component of the MetS is an independent risk factor for cardiovascular disease and together enhances and compounds the atherosclerotic risk in the individual. (kauveryhospital.com)
  • Multimodality Imaging of Aortic Valve Calcification and Function in a Murine Model of Calcific Aortic Valve Disease and Bicuspid Aortic Valve. (yalemedicine.org)
  • Even with the advances of clinical medicine, cardiovascular disease remains the leading cause of morbidity and mortality in the modern era. (mdpi.com)
  • In this Special Issue, we cordially invite researchers as well as clinicians to submit their invaluable studies on cardiovascular disease of children and adults, from bench or bedside. (mdpi.com)
  • The MIMICS-3D-USA Study is a prospective, multicentre, observational study (non-investigational) of the BioMimics 3D Vascular Stent System that evaluates evaluate safety, effectiveness and device performance within a real-world clinical population of patients undergoing femoropopliteal intervention for the treatment of peripheral artery disease. (ctvstexas.com)
  • The premature aging is result of accelerated vascular aging (stiffening and PWV increase) and the prevalence of hypertension is more than doubled in the elderly than in the young population. (jscimedcentral.com)
  • The presence of diabetes and prediabets is associated with increased PWV and synergistically effects vascular stiffness expressed by diabetes and hypertension, too. (jscimedcentral.com)
  • One of the strongest predictors of such manifestations of arteriosclerosis is the pulse wave velocity in aorta, which is a non-invasive measure of the degree of arterial calcification [ 1 ]. (biomedcentral.com)
  • Importantly, mice deficient in both MGP and OPN had twice as much arterial calcification as MGP −/− OPN +/+ at 2 wk, and over 3 times as much at 4 wk, suggesting an inhibitory effect of OPN in vascular calcification. (silverchair.com)
  • Prevention, early identification and effective management of vascular access complications remain an important aspect of managing patients undergoing TAVR. (ahajournals.org)
  • The incidence of vascular complications has varied according to the definition that has been applied. (ahajournals.org)
  • Controlling these factors reduces the risk of acute vascular complications and death from CVD [ 1 , 7 ]. (hindawi.com)
  • He also works with model-based control, e.g., like the artificial pancreas project, but in the context of type-2 diabetes, cystic fibrosis related diabetes, and within the intensive care unit unrelated to diabetes. (cuanschutz.edu)
  • Even a modest increase in body weight may lead to a rather significant increase in the prevalence of cardiovascular morbidity and mortality. (kauveryhospital.com)
  • It must be noted that even a modest rise in body weight can cause a significant rise in the rate of cardiovascular morbidity and mortality. (kauveryhospital.com)
  • Consistently, alizarin red staining and calcium content assay confirmed that Wog inhibited aortic calcification in vitamin D3-overloaded mice. (bvsalud.org)
  • The standard treatment for CAVD is surgical aortic valve replacement, as no non-surgical solutions exist to halt or reverse valve calcification. (pitthonors.blog)
  • He is currently studying the biomechanical progression of aortic aneurysms by modeling the mechanical forces that act on the degenerating vessel wall. (pitt.edu)
  • These events may have clinical consequences, affecting areas such as the cardiovascular and musculoskeletal systems. (naturalproductsinsider.com)
  • Clinical decision-making based on overall cardiovascular risk in addition to individual risk factors can improve outcomes, as demonstrated for antihypertensive treatment [ 12 ]. (springer.com)
  • HTA groups such as NICE and ANAES (Agence Nationale d'Accreditation et d'Evaluation en Sante) in France are seen as being much more influential since they impact on clinical practice and reimbursement. (bmj.com)
  • Clinical variables were obtained from Ningen Dock records, a vascular function test, and a questionnaire on medication, among others. (springeropen.com)
  • The clinical unit of the Research lab is closely integrated with the Cardiology department's research infrastructure, which includes facilities for invasive and non-invasive evaluation of cardiovascular function. (gu.se)
  • This includes the activation of the renin-angiotensin-aldosterone system, abnormal elevations in adipocytokines, and the pro-inflammatory cytokines, that causes the sympathetic nervous system to activate. (kauveryhospital.com)
  • Abnormal calcification begins in the mitochondria. (raypeat.com)
  • Recent studies have suggested that micro calcification in the fibrous cap may increase local tissue stress (depending on the proximity of one micro calcific locus to another, and the orientation of the micro calcification in reference to blood flow), resulting in plaque instability [1]. (clinsurgeryjournal.com)
  • Fourth, the PR defined by OCT may be underestimated because the presence of residual thrombus limits the detection of fibrous cap destruction in OCT. In addition, it is sometimes difficult to detect fibrous cap destruction on the surface of nodular calcifications. (interesjournals.org)
  • Multiplex proteomics could improve understanding and risk prediction of major adverse cardiovascular events (MACE) in type 2 diabetes. (springer.com)
  • This study assessed 80 cardiovascular and inflammatory proteins for biomarker discovery and prediction of MACE in type 2 diabetes. (springer.com)
  • We used gradient-boosted machine learning and lasso regularised Cox regression in a random 75% training subsample to assess whether adding proteins to risk factors included in the Swedish National Diabetes Register risk model would improve the prediction of MACE in the separate 25% test subsample. (springer.com)
  • We identified eight protein biomarkers, four of which are novel, for risk of MACE in community residents with type 2 diabetes, and found improved risk prediction by combining multiplex proteomics with an established risk model. (springer.com)
  • Multiprotein arrays could be useful in identifying individuals with type 2 diabetes who are at highest risk of a cardiovascular event. (springer.com)
  • Cardiovascular prevention is further complicated by increased rates of drug side effects in people with diabetes, including potential adverse glycaemic effects of lipid-modifying agents [ 6 , 7 ]. (springer.com)
  • Sinha S, Haque M (September 04, 2022) Obesity, Diabetes Mellitus, and Vascular Impediment as Consequences of Excess Processed Food Consumption. (diabeets.com)
  • This review explains the probable processes relevant to processed food and obesity, linking diabetes mellitus (DM) with vascular impediments and implications. (diabeets.com)
  • We analyzed baseline data from 476 men and 244 women who participated in "Cardiovascular Risk factors in Patients with Diabetes -a Prospective study in Primary care" study. (biomedcentral.com)
  • Dr. Alonso's primary academic interest is redesigning the system in which care is provided to children and adolescents with type 1 diabetes. (cuanschutz.edu)
  • MetS is consistently associated with high Cardio-Vascular event risk and high incidence of Type 2 Diabetes mellitus. (kauveryhospital.com)
  • The information gleaned from this assay will contribute to our understanding of how a healthy cell becomes calcific, and eventually, to the discovery of new drugs to treat valvular calcification in CAVD. (pitthonors.blog)
  • Her laboratory specialises in investigating the functional relevance of molecular signalling pathways in human and animal endothelial cells and a range of other vascular cell types. (rvc.ac.uk)
  • The group uses in vitro, ex vivo and in vivo cell and molecular approaches to delineate the signalling pathways controlling gene expression and functional responses of human and murine large vessel and microvascular endothelial cells.Caroline was an associate editor of the Biochemical Journal for over 10 years and is a founder member of the European Vascular Biology Organisation and of the London Vascular Biology Forum. (rvc.ac.uk)
  • focus is primarily on vascular cell function with emphasis on understanding molecular control mechanisms. (rvc.ac.uk)
  • Rejuvenation therapies aim to reverse or repair age-related cellular changes such as molecular waste, calcification , tissue stiffening , loss of stem cell function , genetic alterations, and impaired energy production . (fightaging.org)
  • This system uses molecular cloning techniques to generate the TERT split-FAST and STAT5 split-FAST constructs by inserting TERT and STAT5 genes into two distinct recipient plasmids, each containing a different half of FAST. (pitthonors.blog)
  • Using this approach, we have characterized GPCRs expressed in the human cardiovascular system and identified a novel cardiovacular role for transmitters including apelin, chemokines and kisspeptins. (cam.ac.uk)
  • Association between polymorphisms of the renin angiotensin system and carotid stenosis. (cdc.gov)
  • Journal of vascular surgery 2011 Aug 54 (2): 467-73. (cdc.gov)
  • 1 Department of Regenerative Medicine and Advanced Cardiac Therapeutics, 2 Cardiology Division, Department of Internal Medicine, 3 Department of Cardiovascular Surgery, 4 Division of Diagnostic Pathology, 5 Department of Pathology, Keio University School of Medicine, Tokyo, Japan. (jci.org)
  • Using tissues obtained with ethical approval and informed consent at the time of surgery, we measure responses to chemical messengers such as endothelin-1 (ET-1), novel transmitters or drugs as changes in vascular reactivity or the force of contraction of the heart. (cam.ac.uk)
  • European Journal Of Vascular And Endovascular Surgery 2023, 65: e108. (yalemedicine.org)
  • Journal Of Vascular Surgery 2023, 77: 1649-1657. (yalemedicine.org)
  • After open-heart surgery, when both magnesium and vitamin E are drastically needed and could easily be given, the calcification of heart muscles often becomes so severe that it can cause death within a few days. (raypeat.com)
  • Evaluate the safety and efficacy of Medtronic Intrepid™ TMVR System in patients with severe symptomatic mitral regurgitation who are candidates for conventional mitral valve surgery. (ctvstexas.com)
  • PWV measuring provides us to noninvasively assess arterial stiffness and real age of the arteries and thus the risk of cardiovascular events. (jscimedcentral.com)
  • The vascular ageing has consistently been found to be related closely to the chronological age as Thomas Sydenham said, "A man is as old as his arteries" [2]. (jscimedcentral.com)
  • Mice deficient in MGP alone (MGP −/− OPN +/+ ) showed calcification of their arteries as early as 2 weeks (wk) after birth (0.33 ± 0.01 mmol/g dry weight), and the expression of OPN in the calcified arteries was greatly up-regulated compared with MGP wild-types. (silverchair.com)
  • King's College London) fuelled her interest in vascular cellular signalling and her subsequent post-doctoral position with Professor Jeremy Pearson at King's College London (KCL) allowed her to pursue this interest in human endothelial cells. (rvc.ac.uk)
  • She is particularly known for her work on mechanisms of vascular endothelial eicosanoid generation and recent studies have identified biological roles for novel fatty acid metabolites in vascular repair and angiogenesis. (rvc.ac.uk)
  • The International Academy of Cardiology is dedicated to the advancement of global research in cardiovascular medicine through the support of scientific meetings and publications. (cardiologyonline.com)
  • Infinitt Cardiology Suite is a web-based PACS and reporting system for cardiology and vascular imaging, EKG and nuclear medicine. (itnonline.com)
  • Infinitt Cardiology Suite can be used as a stand-alone system or become fully integrated with Infinitt PACS, consolidating data for the EHR. (itnonline.com)
  • Nonsteroidal anti-inflammatory drugs (NSAIDs), both non-selective and selective cyclooxygenase-2 (COX-2) inhibitors, are very widely prescribed, but they may cause increased blood pressure (BP) and adverse cardiovascular (CV) events. (cardiologyonline.com)
  • The atherosclerotic process is accelerated by a myriad of factors, such as the release of inflammatory chemokines and cytokines, the generation of reactive oxygen species (ROS), growth factors, and the proliferation of vascular smooth muscle cells. (hindawi.com)
  • The enzyme's C-terminal domain has been linked to cardiovascular protective and anti-inflammatory effects. (frontiersin.org)
  • PWV is a crucial vascular and hemodynamic parameter that is used to assess the stiffness of aorta as a large vessel. (jscimedcentral.com)
  • Cardiovascular (CV) aging is an important factor that determines vascular stiffness. (jscimedcentral.com)
  • The mammography viewer supports breast tomosynthesis with specialized features such as mammography tomosynthesis CAD SR, direct movement to lesions in frames, and tomo slab rendering to improve the visibility of micro- calcification. (itnonline.com)
  • Cholesterol metabolism in the brain is independent of peripheral tissues due to the blood-brain barrier (BBB) that impairs the entrance of the protein-bound lipid into the central nervous system (CNS). (frontiersin.org)
  • We have shown that ACE2 cleaves [Pyr 1 ]apelin-13 to [Pyr 1 ]Apelin-13 1-12 and this cleavage product is expressed in human cardiovascular tissues. (cam.ac.uk)
  • Instead, it provides significant amounts of several natural ingredients that the body can use to improve its function and health in all tissues, and, especially so with cardiovascular tissues. (healthy-living.org)
  • Studies show that supplementing with significant amounts of Lysine (at different times than Arginine) and taking proline and mineral ascorbates at the same time as Lysine, gives a huge boost to collagen formation in cardiovascular wall tissues. (healthy-living.org)
  • In other words, Cardio Pro gives the body the Lysine it needs and the ample of other co-factor nutrients so that it can get to the task of restoring the health of its cardiovascular and other tissues. (healthy-living.org)
  • Chavkin NW, Leaf EM, Brooks KE, Wallingford MC, Lunn SM, Giachelli CM. Adaptor protein RapGEF1 is required for ERK1/2 signaling in response to elevated phosphate in vascular smooth muscle cells. (navbo.org)
  • Study reports suggested that high blood level of phosphate causes vascular ossification through the deposition of Ca 2+ and substantially alters fibroblast growth factor-23 (FGF23) and calcitriol. (diabeets.com)
  • Measuring circulating proteins with presumed roles in cardiovascular pathology by targeted proteomics is a promising approach for biomarker discovery [ 15 ]. (springer.com)
  • The 25% of patients in whom troponin levels were measured accounted for 80% of TVMIs, reported Dean J. Kereiakes, MD, The Christ Hospital Heart and Vascular Center, Cincinnati, at TCT Connect, the virtual edition of Transcatheter Cardiovascular Therapeutics (TCT) 2020 . (medscape.com)
  • In April 2020, a frailty health checkup using a 15-item questionnaire called the "the Questionnaire for Latter-stage Elderly People," which partially overlaps with the KCL questionnaire, was launched as a medical care system for people aged 75 years and older [ 3 ]. (springeropen.com)
  • Primary Study Arm - TAAA and Pararenal aneurysms requiring only TAMBE System. (ctvstexas.com)
  • Caroline is a Professor of Vascular Cell Biology and is Head of Comparative Biomedical Sciences. (rvc.ac.uk)
  • Caroline was appointed to a Lectureship position at the Royal Veterinary College in late 1997 and now holds a personal Chair in Vascular Cell Biology. (rvc.ac.uk)
  • Caroline is an internationally recognised expert in vascular cell signalling and biology with 20 years' experience in the field. (rvc.ac.uk)
  • He was the Chair of the Bioengineering Division of the American Society of Mechanical Engineers (ASME), the first non-MD President of the International Society for Applied Cardiovascular Biology, and the Secretary of the Executive Committee of the Biomedical Engineering Society (BMES), for which he served on the Board of Directors for 10 years. (pitt.edu)
  • 2012) Elected President, International Society for Applied Cardiovascular Biology (ISACB). (pitt.edu)
  • 2006) Named to Executive Council of the International Society for Applied Cardiovascular Biology (ISACB). (pitt.edu)
  • Newer glucose-lowering drugs such as sodium-glucose co-transporter 2 inhibitors, and cholesterol-modifying agents such as proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors, in addition to standard treatment reduce cardiovascular risk in high-risk individuals [ 8 , 9 ]. (springer.com)
  • Multivariate ordinal logistic regression models were used to assess risk factors. (springeropen.com)
  • Based Short-Term Risk Model for Breast Cancer. (cancercentrum.se)
  • Our group is interested in defining the precise cellular mechanisms that govern how a healthy vascular cell becomes calcific and leverage these insights for novel treatments. (pitthonors.blog)
  • Journal of Vascular Research. (navbo.org)
  • Placental Calcification: Longstanding Questions and New Biomedical Research Directions. (navbo.org)
  • Learn more about our Research Laboratories in Biomedical Engineering and our three core research strength areas of Basic Research in Engineering Tissue Model Systems, Diagnostic Bioimaging and Sensor Systems, and Therapeutic and Reparative Neurotechnology. (fiu.edu)
  • In patients receiving first‐generation valves, ≈12% of patients experienced a major vascular complication and 16% a life‐threatening bleed, as defined by the Valve Academic Research Consortium criteria. (ahajournals.org)
  • In conclusion, this Special Issue is to underscore the key importance of both basic and cardiovascular research. (mdpi.com)
  • The current manuscript will elaborate on the relation of fast-food consumption with obesity and its cardiovascular relevance. (diabeets.com)
  • Cardio Pro also contains bioflavanoids (as hesperidin from citrus peels) - The flavonoids present in citrus fruits have been shown to be highly beneficial to the cardiovascular system by supplying additional nutrient tools that the body uses in controlling free radicals. (healthy-living.org)
  • By 2005 observational studies and small randomized trials suggested excess cardiovascular (CV) adversity with some NSAIDs. (cardiologyonline.com)
  • He also serves as a Director of the Center for Vascular Remodeling and Regeneration, the Co-Director of the Center for Medical Innovation, the Acting Director of the University's GRID Institute, as well as the Director of the Vascular Bioengineering Laboratory. (pitt.edu)
  • Doses were selected based on the Company's preclinical studies and PK/PD modeling. (inozyme.com)
  • The preclinical work focuses on animal models of myocardial ischemia-reperfusion injury, which is an experimental model for STEMI, as well as ex-vivo models of myocardial ischemia. (gu.se)
  • Birth defects which have been documented following isotretinoin capsules exposure include abnormalities of the face, eyes, ears, skull, central nervous system, cardiovascular system, and thymus and parathyroid glands. (nih.gov)
  • Vitamins D3 and K2 may help support the cardiovascular and musculoskeletal systems, particularly for those supplementing with calcium. (naturalproductsinsider.com)
  • Magnesium deficiency and calcium deficiency have some similar symptoms (such as cramping), but magnesium is antagonistic to calcium in many systems. (raypeat.com)
  • Using a mouse model, we investigated cardiac remodeling under the influence of acute cigarette smoke (CS) exposure following ischemic injury in both sexes. (biomedcentral.com)
  • We hypothesize that the disruption of this binding interaction will reduce calcification in patients with CAVD. (pitthonors.blog)
  • My ultimate career goal is to become a cardiologist and a role model of health and fitness to my future patients, family, and peers. (pitthonors.blog)
  • APOLLO Trial - Transcatheter Mitral Valve Replacement with the Medtronic Intrepid™ TMVR System in patients with severe symptomatic mitral regurgitation. (ctvstexas.com)
  • We assessed cardiac response in two experimental models of CKD and tested macrophage and chemokine implication in monocytopenic CCR2 −/− and anti-CXCL10 treated mice. (biomedcentral.com)
  • A persistent sympathetic nervous system activation typically leads to an increase in the resting heart rate, circulating blood volume, cardiac output, renal sodium retention, ventricular end-diastolic volume (pre-load), and/or blood pressure. (kauveryhospital.com)
  • Johnathan D. Tune et al Cardiovascular Consequences of Metabolic Syndrome Transl Res. (kauveryhospital.com)
  • This study provides new insight into the role of the innate immune system in uremic cardiomyopathy. (biomedcentral.com)
  • Pancreatic islet cells are part of the diffuse neuroendocrine system of the gut and pancreatic endocrine system. (medscape.com)
  • There are numerous studies that are starting to show the value of Vitamin C in cardiovascular health, especially the ascorbate and flavonoid types of Vitamin C. (healthy-living.org)