Loading...
  • concentrations of cadmium
  • The exposure of mussels, Mytilus edulis , collected from Whitsand Bay, southwest England, in August 1988, to sublethal concentrations of cadmium (400 µ g l −1 ) for 65 d resulted in the induction of metallothionein (MT) synthesis in the soft tissues. (springer.com)
  • Ovariectomized estrogen reporter ERE-luciferase (ERE-luc) mice were maintained on diets that intrinsically contain increasing concentrations of cadmium and enterolactone precursors for three and 21 days. (diva-portal.org)
  • In view of these alterations of the defense mechanisms of aquatic invertebrates, which consist of cellular and humoral responses, the aim of this study was to determine the effect on survival, clotting time, hemocyanin, number of hemocytes, and phenoloxidase activity of Litopenaeus vannamei juveniles exposed to four sublethal concentrations of cadmium. (hindawi.com)
  • They divided the participants up into fourths based on the concentrations of cadmium found in their bloodstream, finding that people in the highest group had telomeres that were about six percent shorter than those in the lowest group. (medicalnewstoday.com)
  • Furthermore
  • 2015). Furthermore, cadmium disrupts the F-actin cytoskeleton in rat renal mesangial cells, which is mediated by gelsolin translocation, programmed cell death, and F-actin depolymerization through formation of a CAP1-cofilin-F-actin complex (Apostolova et al. (deepdyve.com)
  • intake
  • The use of these compounds in the food industry results in an increased total level of xenoestrogens and sex steroids in processed foods, such as meat or milk, whose intake contributes significantly to daily exposures. (nutritionfacts.org)
  • Compared to animals on basal purified diet, mice consuming experimental diets were exposed to significantly higher levels of cadmium and enterolactone, yet the exposure remained comparable to typical human dietary intake. (diva-portal.org)
  • The results of that study reveal that post-menopausal women with a fairly high daily dietary intake of cadmium also have a 21 percent increased risk for developing breast cancer. (newsinferno.com)
  • Around 910,000 adults in France alone exceed tolerable intake limits of cadmium by 90%," she said. (newswire.ca)
  • In that opinion, EFSA established a tolerable weekly intake (TWI) of 2,5 μg/kg body weight for cadmium. (europa.eu)
  • In its 'Statement on tolerable weekly intake for cadmium' ( 4 ) , EFSA took into account the recent risk assessment carried out by the Joint FAO/WHO Expert Committee on Food Additives (JECFA) ( 5 ) and confirmed the TWI of 2,5 μg/kg body weight. (europa.eu)
  • pigments
  • The metal was first discovered in Germany in 1817, and has been used for a variety of uses, including the manufacturing of pigments, in nickel-cadmium, rechargeable batteries, solar cells, metal coatings, plastic stabilizers, and corrosion protection for iron and steel. (progressivehealth.com)
  • cytosolic
  • Gel chromatography of heat-treated cytosolic extracts showed that the accumulated cadmium is bound principally to the newly formed metallothioneins. (springer.com)
  • 2015). In addition, cadmium-induced cytotoxicity in primary rat proximal tubular cells can be attributed to the inhibition of the cytosolic Ca2+ dependent autophagosome-lysosome fusion (Liu et al. (deepdyve.com)
  • chloride
  • Forty pregnant Wistar rats were divided into three groups: 1) control, 2) 10 mg kg -1 cadmium chloride per day, and 3) 20 mg kg -1 cadmium chloride per day. (scielo.br)
  • dietary exposure
  • In a refined exposure assessment carried out by EFSA in its scientific report on 'Cadmium dietary exposure in the European population' ( 6 ) using the new Comprehensive Food Consumption database which contains updated information on food consumption figures for the different Member States and for different age groups of the population, more detailed information on the particular food commodities that contribute to exposure are given by age group. (europa.eu)
  • kidney
  • Cadmium can cause kidney failure and has been statistically associated with an increased risk of cancer and can also cause bone damage. (newswire.ca)
  • The CONTAM Panel further concluded that, although adverse effects on kidney function are unlikely to occur for an individual exposed at this level, exposure to cadmium at the population level should be reduced. (europa.eu)
  • 2009 ). Consumption of Cd resulted in stomach irritation, vomiting and diarrhea, while long-term exposure caused kidney disease, cancer and fragility at birth. (springer.com)
  • sperm
  • 2017). Cadmium can disrupt the blood-testis barrier in the testis even at low concentrations by damaging the testis vasculature and exerting the cytotoxicity on Sertoli and Leydig cells, resulting in a decrease in sperm quality, fertilization capacity and subsequent early embryonic development (de Angelis et al. (deepdyve.com)
  • There is also good evidence for considerable geographical variation in sperm counts, which could indicate variation in environmental exposures and/or in genetic/ethnic influences (reviewed in Sharpe 2009 ). (royalsocietypublishing.org)
  • According to the results of a study reported in the Journal of Fertility and Sterility, exposure to bisphenol A (BPA) is linked to reduced semen quality and sperm count. (emed.com.au)
  • detoxification
  • Overall, and on the canopy level, this inhibitory effect might result in a lower detoxification capacity for organic pollutants and thus interfere with phytoremediation. (springer.com)
  • Metallothionein (MT) a carrier protein plays an important role in the detoxification process of cadmium in human. (ccsenet.org)
  • human
  • Thus, whenever possible, a context that mimics human exposure should be tested along with pure compounds. (diva-portal.org)
  • Some Cadmium is released into the air by forest fires and volcanoes, while the remainder is the result of human activities, such as manufacturing. (gohealthynext.com)
  • 2017). Human exposure occurs mainly from consumption of contaminated food, active or passive inhalation of tobacco smoke and air inhalation in a metal industry area. (deepdyve.com)
  • Excessive levels of cadmium in food can have implications for human health and excessive levels of cadmium in soils can restrict land-use. (newswire.ca)
  • Food is the dominant source of human exposure in the non-smoking population. (newswire.ca)
  • For this reason, since 2012, the National Institute of Environmental Research and university of Ulsan have been carrying a study named "Monitoring of Exposure to Environmental Pollutants and Health Effects of Inhabitants in Industrial Complexes" to assess the human health impact of potentially hazardous compounds emitted from large-scale industrial complexes. (biomedcentral.com)
  • Extensive research established that scalp hair element levels are related to human systemic levels. (drbuttar.com)
  • There will be a special symposium on 'Advances in bioaccessibility methodology to determine human and ecological bioavailability, exposure, and risk from ingestion of trace element contaminated soils' at the 2011 ICOBTE conference in Florence, Italy on 5th July 2011 . (bgs.ac.uk)
  • Requirements for site remediation are frequently based on the potential for contaminants in soil to pose unacceptable health risks following human exposures. (bgs.ac.uk)
  • Because of this, the metal contents of the marine biota are under continuous scrutiny [ 4 , 5 ], and among these the levels of cadmium detected in different aquatic organisms of the coastal environments of NW Mexico indicate that this metal might become of concern for aquatic life and possibly for human health [ 6 ]. (hindawi.com)
  • detrimental
  • Cadmium has several detrimental effects in aquatic organisms, since it affects respiration and osmoregulation because it causes structural and physiological damages to gills [ 7 , 8 ]. (hindawi.com)
  • 2016
  • 2016). The extensive deleterious effects of cadmium on the reproductive system and developing embryos have been described, especially in the male (de Angelis et al. (deepdyve.com)
  • xylene
  • The American Conference of Governmental Industrial Hygienists has recognized the concern for ototoxin exposure by recommending audiograms for workers exposed to ethyl benzene, styrene, toluene, and xylene in non-noise environments. (lww.com)
  • Toxicological
  • It is well-known an exposure to these metals can contribute for a broad spectrum of carcinogenic, mutagenic and/or toxicological effects [21- (sapub.org)
  • 1989
  • Anthropogenic emissions to the air are approximately 34,000 metric tons per year (USEPA, 1989), Absorption of benzene varies with route of exposure. (ghanaweb.com)
  • Heavy
  • Therefore, when evaluating heavy metal levels in the body at a low level of exposure, age, gender, and smoking status must be adjusted, as they are significant confounding factors. (biomedcentral.com)
  • When a heavy metal mixture containing Na 2 HAsO 4 , CdSO 4 and PbCl 2 was applied to cultures, both GSH and GSSG levels declined. (springer.com)
  • Recent studies have shown that exposure to environmental toxins, specifically the heavy metal cadmium, can have a negative effect on your bones- leading to an increased risk for fractures and a reduction in bone density. (progressivehealth.com)
  • Measurement of T3 and T4 levels may thus be utilized as a reliable indicator of heavy metal lethality. (ithyroid.com)
  • organs
  • Male sexual behavior, histological analysis and weight of organs as well as serum testosterone levels were assessed. (scielo.br)
  • Associations
  • Associations were relatively weak at an individual level, with about 1-4% change in thyroid hormones per interquartile range increase in Hg or Cd. (nih.gov)
  • Studies also showed significant associations between BCd and fibrinogen level and thrombin time among the women with myoma and endometrial cancer, as well as in healthy women. (ijomeh.eu)
  • Some studies have reported associations between cadmium and impaired fasting glucose and diabetes. (jove.com)
  • occurs
  • When evaluating the effect of exposure combinations, toluene and carbon monoxide worsen hearing loss when exposure occurs simultaneously with noise ( Toxicol Ind Health . (lww.com)
  • cereals
  • According to the scientific opinion on cadmium in food of the CONTAM Panel, the food groups that contribute to the major part of the dietary cadmium exposure, primarily because of the high consumption, are cereals and cereals products, vegetables, nuts and pulses, starchy roots or potatoes and meat and meat products. (europa.eu)
  • embryonic
  • The embryonic development after fertilization was also impaired even when the potential hazards of cadmium on the spermatozoa or the genital tract have been excluded by fertilization and embryonic development in culture. (deepdyve.com)
  • Finally, cadmium exposure affected the levels of H3K9me2 and H4K12ac in the oocyte, which are closely associated with the acquisition of oocyte developmental competence and subsequent embryonic development. (deepdyve.com)
  • In conclusion, cadmium exposure in female mice impaired meiotic maturation of oocytes and subsequent embryonic development by affecting the cytoskeletal organization, mitochondrial function, and histone modifications. (deepdyve.com)
  • risks
  • Although bone density loss is not the first side effect that most people think about when considering the dangers of cadmium poisoning, the risks are shocking. (progressivehealth.com)