• Erdogan Z, Erdogan S, Celik S, Unlu A. Effects of ascorbic acid on cadmium-induced oxidative stress and performance of broilers. (setpublisher.com)
  • Aly HA, Khafagy RM (2014) Tau reverses endosulfan-induced oxidative stress and apoptosis in adult rat testis. (springer.com)
  • Das J, Ghosh J, Manna P, Sil PC (2012a) Tau protects rat testes against doxorubicin-induced oxidative stress as well as p53, Fas and caspase 12-mediated apoptosis. (springer.com)
  • Based on this current study, it was evident that aluminum chloride induced oxidative stress and retarded reproduction in males whereas Ananas comosus mitigated reproduction in males by improving sperm parameters and microarchitecture of the testes. (springeropen.com)
  • The present study was undertaken to investigate the protective roles of Adansonia digitata (African baobab) Cucumeropsis mannii (Melon), Abelmoschus esculentus (Okro), on lipid profile, bone health, and selected organs (liver, kidney, brain, and testis) against cadmium-induced toxicity in rabbits. (ajol.info)
  • 2006, "The toxicity of cadmium and resulting hazards for human health", Journal of Occupational Medicine and Toxicology, v. 1, рp. (ujoh.org)
  • FK506, a calcineurin inhibitor, prevents cadmium-induced testicular toxicity in mice. (cdc.gov)
  • The goal of this study was to fine map and identify the cdm gene, a gene that when mutated prevents cadmium-induced testicular toxicity in mouse strains with a mutation in this gene. (cdc.gov)
  • Ppp3ca-/- mice were investigated but were found to exhibit endogenous testicular abnormalities, making them an inappropriate model for determining whether the inactivation of the Ppp3ca gene would afford protection from cadmium-induced testicular toxicity. (cdc.gov)
  • The protection afforded by FK506, found by the current study, indicated that CN is likely to be important in the mechanism of cadmium toxicity in the testis and possibly other organs. (cdc.gov)
  • Protective role of selenium against renal toxicity induced by cadmium in rats. (setpublisher.com)
  • In vitro characterization of the human hepatocellular carcinoma (hepg2) cell lines an in vitro model of cadmium toxicity studies. (setpublisher.com)
  • A number of non-essential metals, like cadmium, lead and mercury are not at all necessary for life but, when introduced into the human environment, they pose serious problems on account of their toxicity. (rsc.org)
  • Metal toxicity 1 can be caused by both metal ions, which are considered to be essential for humans, like iron and copper, as well as by non-essential metals, like cadmium, lead and mercury, which are not at all necessary for life but which, when introduced into the human environment, can have toxic effects, often with disastrous consequences. (rsc.org)
  • Cadmium from smoking cigarettes is more likely to pose a health concern than cadmium … "Unfortunately, the human body finds it much more difficult to excrete cadmium than other toxic metals, and its presence in many nutritious foods means it is critical to continue reducing sources of environmental pollution that contribute to its presence in air, soil and water," says Hu. (feministlawprofessors.com)
  • Cd is primarily toxic to the kidney, especially to the pro … Zinc ores contain up … Cadmium releases can be carried to and deposited on areas remote from the sources of emission by means of long-range atmospheric transport. (feministlawprofessors.com)
  • Cadmium (Cd), a by-product of zinc production, is one of the most toxic elements to which man can be exposed at work or in the environment. (feministlawprofessors.com)
  • Determination of the content of cadmium, macro- and microelements in the inner organs allows assessing cadmium toxicokinetics in the body, predicting the pathogenetic features of its toxic effects, especially in the post-exposure period, as well as studying the peculiarities of the pathogenesis of its organotoxic action. (ujoh.org)
  • Dr. Young also presented the findings of a group of scientists identifying toxic aluminium, graphene oxide, cadmium selenide, bismuth, stainless steel, and parasites in the Pfizer-BioNtech, Moderna, Johnson & Johnson and AstraZeneca vaccines in Newsbreak 133 at Ramola D Reports recently. (everydayconcerned.net)
  • Cadmium is found at low concentrations in the Earth's crust, mainly as the sulfide in zinc-containing mineral deposits. (inchem.org)
  • Among the important compounds of cadmium are cadmium oxide (used in batteries, as an intermediate and catalyst and in electroplating), cadmium sulfide (used as a pigment), cadmium sulfate (used as an intermediate and in electroplating) and cadmium stearate (used as a plastics stabilizer). (inchem.org)
  • acetate, chloride and sulfate, whereas cadmium oxide, carbonate and sulfide are almost insoluble (1). (feministlawprofessors.com)
  • The aim of the study was - to compare the content of micro and macro elements in the liver and kidneys of experimental animals after exposure to cadmium sulfide NP and cadmium chloride. (ujoh.org)
  • 2014, "Genotoxicity and Cytotoxicity of Cadmium Sulfide Nanomaterials to Mice: Comparison Between Nanorods and Nanodots", Environmental Engineering Science, v. 31 (7), pp. 373- 380. (ujoh.org)
  • Occupations in which the highest potential exposures occur include cadmium production and refining, nickel-cadmium battery manufacture, cadmium pigment manufacture and formulation, cadmium alloy production, mechanical plating, zinc smelting, soldering and polyvinylchloride compounding. (inchem.org)
  • The median concentration of zinc in 726 filtered samples of water taken from rivers and lakes of the United States in November 1971 was close to 20 μg/l, and the median concentration of cadmium was a little below 1 μg/l. 6. (feministlawprofessors.com)
  • Cadmium occurs naturally in zinc, in lead and copper ores, in coal and other fossil fuels, in shales and is released during volcanic action. (feministlawprofessors.com)
  • MTs have the capacity to bind both physiological (such as zinc, copper, selenium) and xenobiotic (such as cadmium, mercury, silver, arsenic, lead) heavy metals through the thiol group of its cysteine residues, which represent nearly 30% of its constituent amino acid residues. (wikipedia.org)
  • Zinc and Cadmium are tetrahedrally coordinated to cysteine residues, and each metallothionein protein molecule may bind up to 7 atoms of Zn or Cd. (wikipedia.org)
  • They include paracetamol, aspirin, and nsaids zinc chloride fumes zinc oxide fumes generated during welding, galvanizing, or smelting. (reflectionsbodysolutions.com)
  • Occupational exposure to cadmium and cadmium compounds occurs mainly in the form of airborne dust and fume. (inchem.org)
  • The prolonged exposure to cadmium compounds also led to the increase of copper levels and decrease in iron and selenium levels in the kidneys. (ujoh.org)
  • The intensive accumulation of cadmium and imbalance of trace elements can play a leading role in hepatotoxic and nephrotoxic effects of cadmium compounds in nano- and ionic form. (ujoh.org)
  • The effect of phenobarbital on the biliary excretion of metals in rats was com-pared among methyl mercury, inorganic mercury and cadmium compounds from which phenobarbital prevented animals. (go.jp)
  • In the groups co-treated with aluminum chloride and Ananas comosus extract, there was improvement in sperm volume, motility, total count, progressive assessment, and morphology. (springeropen.com)
  • 0.05) in testosterone hormone in the negative control group, but there was an increase in the aluminum chloride and Ananas comosus extract co-treated groups. (springeropen.com)
  • Similarly, in co-treated aluminum chloride and Ananas comosus extract, the degenerative seminiferous tubule histoarchitecture due to aluminum chloride in the negative control group was enhanced. (springeropen.com)
  • In rats given an i.v. administration of 1mg/kg Cd or Hg, large amounts of cadmium (15.1% of the dose) were found in the bile within 5 hr after the dose, but small amounts of mercury were excreted with bile (1.4 and 3.3% in inorganic mercury and methyl mercury groups, respectively). (go.jp)
  • Phenobarbital significantly increased the biliary excretion of methyl mercury and cadmium (154 and 140% of controls, respectively), but not that of inorganic mercury. (go.jp)
  • Concentrations of methyl mercury in the bile also increased in the treated rats, but those of cadmium did not change when compared with controls. (go.jp)
  • Urinary and blood cadmium concentrations are generally much lower in non-occupationally exposed people, for whom the most important sources of exposure are cigarette smoking and, especially in polluted areas, eating certain foods (e.g. rice). (inchem.org)
  • A case-control analysis of lung cancer did not show any association with exposure to cadmium. (inchem.org)
  • Excess mortality from lung cancer was reported among workers employed in a US cadmium recovery plant, and a dose-response relationship was demonstrated between estimated cumulative exposure to cadmium and lung cancer risk. (inchem.org)
  • In a large cohort of workers from 17 cadmium processing plants in the United Kingdom, decreased mortality from prostatic cancer was observed, while that from lung cancer was increased in the overall cohort and there were suggested trends with duration of employment and with intensity of exposure. (inchem.org)
  • The increase in lung cancer risk was stronger in the small proportion of workers with high cadmium exposure. (inchem.org)
  • Excess mortality from stomach cancer, which was not related to intensity of cadmium exposure, was also reported among these workers. (inchem.org)
  • Constraints that influence the assessment of both lung and prostatic cancer risk are that the number of long-term, highly exposed workers is small, the historical data on exposure to cadmium are limited, particularly for the non-US plants, and the ability to define and examine a gradient of cumulative exposure varies across studies. (inchem.org)
  • The results revealed that cadmium exposure caused a significant increase in serum total cholesterol, triacylglycerol, low density lipoprotein cholesterol concentration, and atherogenic index in rabbits exposed to cadmium. (ajol.info)
  • Cadmium exposure also reduced bone calcium concentration. (ajol.info)
  • Citrullus lanatus and Abelmoschus esculentus prevented organ damage induced by cadmium exposure. (ajol.info)
  • In the liver of experimental animals the most intensive accumulation of cadmium was observed after exposure to CdCl 2 , especially in the post-exposure period. (ujoh.org)
  • There was a higher content of cadmium after exposure to CdS NP-6 nm, as compare to CdS NP 9-11 nm. (ujoh.org)
  • Significant accumulation of cadmium was recorded in the kidneys, especially in the post-exposure period, which can indicate an intensive elimination from the body. (ujoh.org)
  • A significant accumulation of cadmium was recorded in the kidneys, especially in the post-exposure period, which can point to an intensive elimination from the body. (ujoh.org)
  • 1998, "Health effects of cadmium exposure - a review of the literature and a risk estimate", Scandinavian Journal of Work, Environment & Health, v. 1, pp. 1-52. (ujoh.org)
  • 2014, "Non-renal effects and the risk assessment of environmental cadmium exposure", Environmental Health Perspectives, v. 122 (5), р. (ujoh.org)
  • Berzina N, Markovs J, Isajevs S, Apsite M, Smirnova G. Cadmium-induced enteropathy in domestic cocks: a biochemical and histological study after subchronic exposure. (setpublisher.com)
  • The introduction of cadmium nanoparticles (NP) in production makes it necessary to study the mechanism of their action both at the cellular level and at the level of organs and systems, to determine biomarkers of their effects, especially as comparing to their ionic forms. (ujoh.org)
  • Cadmium, a ubiquitous environmental contaminant, damages several major organs in humans and other mammals. (cdc.gov)
  • 4-7] One human study showed that the daily consumption of humic acid with bound complex micro-elements for six weeks decreased uptake and increased urinary excretion of cadmium in alkaline battery production workers. (medicaldetectivemd.com)
  • At the end of the administration, blood, liver, kidney, brain, and testes were harvested from the rabbits for biochemical and histological analysis. (ajol.info)
  • The three vegetables reversed the cadmium-induced up-regulation of total cholesterol and triacylglycerol in the liver, kidney, and brain but not in the testis. (ajol.info)
  • Long-term Cd poisoning may lead to damage to the kidneys, liver, testes and prostate. (feministlawprofessors.com)
  • Along with the increase in the cadmium content in the liver, the growth of the content of copper, iron (more intensively with CdCl 2 ), iron, and lower selenium levels were recorded (especially for CdS NP 4-6 nm). (ujoh.org)
  • The study was carried out on the effects of cadmium (Cd) on liver, gizzard and kidney of Larus argentatus. (setpublisher.com)
  • Major changes were noted at high dose of cadmium chloride in liver, kidney and gizzard. (setpublisher.com)
  • With lower dosage at 10 days, the concentration of 32 P was highest in the kidney (10ppm), followed by liver (9ppm), blood (8ppm), heart and spleen (5ppm), lung (4ppm), intestine (3ppm), muscle (3ppm), and bone, brain and testes (2ppm). (go.jp)
  • Tissue extracts of Mouse Testis (Lane 6) and Mouse Kidney (Lane 7) were electrophoresed using NuPAGE™ 3-8% Tris-Acetate Protein Gel (Product # EA0378BOX). (thermofisher.com)
  • The study was conducted on mature male Wistar rats 160-180 g, intraperitoneally injected with CdS NP of 4-6 nm of 9-11 nm size as well as CdCl 2 in 0,08 mg/kg/day dose adjusted to cadmium. (ujoh.org)
  • At high doses (5 mg/kg cadmium chloride or higher), testicular damage in mice, rats, and other rodents includes interstitial edema, hemorrhage, and changes in the seminiferous tubules affecting spermatogenesis. (cdc.gov)
  • In tests, Lab rats saw their testosterone production reduced by as much as 40 when the leidig cells in their testes was exposed to various HMG-CoA reductase inhibitors, creatine bien fait. (lastexperts.com)
  • Cadmium supplement triggers endoplasmic reticulum stress response and cytotoxicity in primary chicken hepatocytes. (setpublisher.com)
  • These biochemical alterations in the sperm producing cells of the testis were observed apriori to morphological changes detectable under light microscope. (go.jp)
  • An inhibitor of CN, the immunosuppressant, FK506, prevented cadmium-induced testicular damage in five pathological categories, including vascular endothelial and seminiferous epithelial endpoints. (cdc.gov)
  • Akyolcu MC, Ozcelik D, Dursun S, Toplan S, Kahraman R. Accumulation of cadmium in tissue and its effect on live performance. (setpublisher.com)
  • Acidification of cadmium-containing soils and sediments may increase the concentrations of cadmium in surface waters and crops. (inchem.org)
  • With increasing pollution and emission of cadmium, its levels in agricultural soils are increasing. (feministlawprofessors.com)
  • Biochemical alterations in seminiferous tubules of rat, treated with manganese chloride (MnCl 2 .4H 2 O, 8 mg/kg) for 60 days were studied. (go.jp)
  • The vial also contains ferric chloride at a concentration of 3.5 μg/mL (ferric ion, 1.2 μg/mL). (globalrph.com)
  • Furthermore, using the developed, assay the epigenetic effects of three endocrine disruptors, simazine, propiconazole, and cadmium chloride (CdCl2) on in-vitro cultured single blastocysts were revealed. (ndltd.org)
  • 3] Furthermore, humic substances, as found in shilajit, have been shown to affect the distribution, metabolism, and absorption of heavy metals, such as cadmium and lead. (medicaldetectivemd.com)
  • These vegetables however play different protective roles against cadmium exposed rabbits. (ajol.info)
  • Two small copper-cadmium alloy plants were studied in the United Kingdom. (inchem.org)
  • 2007, "Cadmium-induced Cancers in Animals and in Humans", International Journal of Occupational and Environmental Health, v. 13 (2), pp. 202-212. (ujoh.org)
  • Cadmium as environmental hazard. (setpublisher.com)
  • 2013). It accumulates in the body through food and water, but also through the air we breathe and the environment in … Cadmium and Human Health. (feministlawprofessors.com)
  • Cadmium is easily absorbed and accumulates in tissues, and its main sources in our diet are fish and cereal products (Olmedo et al. (feministlawprofessors.com)
  • these are some of the most popular and most common cadmium-based products. (feministlawprofessors.com)
  • However, background levels of cadmium in food, water, and ambient air are not a health concern for the general North American population. (feministlawprofessors.com)
  • A number of early studies reported an increased risk for prostatic cancer among cadmium workers, but the results of later studies were not consistent. (inchem.org)
  • Early and recent studies provide consistent evidence that the risk for lung cancer is increased among workers exposed to cadmium. (inchem.org)
  • Cadmium may enter drinking water sources naturally (leaching from soil) , as a result of human activities (as a cadmium in drinking water. (feministlawprofessors.com)
  • Cadmium can also contaminate drinking water through corrosion of galvanized pipes and cadmium-containing solders. (feministlawprofessors.com)
  • The indium In-111 pentetreotide solution is suitable for intravenous administration as is, or it may be diluted to a maximum volume of 3.0 mL with 0.9% Sodium Chloride Injection, U.S.P., immediately before intravenous administration. (globalrph.com)