• Vasoactive intestinal peptide tumor is a rare neuroendocrine neoplasm which causes voluminous watery diarrhea via hypersecretion of electrolytes and water from the intestinal mucosa through a vasoactive intestinal peptide-mediated, cyclic AMP-dependent mechanism. (hindawi.com)
  • A review of literature was performed using MEDLINE, Pubmed, and Cochrane databases in collection of data using MeSH terms including vasoactive intestinal peptide, VIPoma, and WDHA. (hindawi.com)
  • Vasoactive intestinal peptide tumor is a rare neoplasm associated with significant morbidity and mortality through secretion of water and electrolytes in the gastrointestinal tract. (hindawi.com)
  • For instance, peptides called enkephalins are natural opiate s created by the brain . (everything2.com)
  • Well-known examples are the opioids (e.g., enkephalins), so named because they are endogenous (produced in the human body) peptides (short chains of amino acids) with a strong affinity for the receptors that bind opiate drugs, such as morphine and heroin. (britannica.com)
  • The pharmacologic interaction with immune receptors (p-i) model states that drugs can induce the formation of HLA-drug complexes that can activate T-cell immune responses directly without requiring a specific peptide ligand ( 8 ). (pnas.org)
  • Angiotensin -converting enzyme (ACE) is an enzyme that targets a specific peptide bond, forming a chemical signal that increases blood pressure . (encyclopedia.com)
  • This is an important breakthrough because peptides are considered to be a possible solution in the fight against antibiotic-resistant bacteria. (empa.ch)
  • The research carried out by Empa and the University of Copenhagen could, therefore, be a first step in the successful fight against antibiotic-resistant bacteria, as peptides use a different mechanism from that used by antibiotics and destroy the membrane of bacteria. (empa.ch)
  • For example, cytotoxic peptides such as KLAK are conjugated onto dendrimers (polymeric materials with nanometer-scale dimensions) to enhance intracellular delivery and deep tumor penetration capacity. (news-medical.net)
  • Single-blind case-control studies have demonstrated that marine collagen peptides improve skin elasticity and sebum production in healthy participants. (news-medical.net)
  • os estudos Único-cegos do caso-controle demonstraram que os peptides marinhos do colagénio melhoram a elasticidade de pele e a produção do sebum em participantes saudáveis. (news-medical.net)
  • Other nonribosomal peptides are most common in unicellular organisms , plants , and fungi and are synthesized by modular enzyme complexes called nonribosomal peptide synthetases . (wikipedia.org)
  • The bonds between peptides can be broken by enzyme s known as peptidases . (everything2.com)
  • In type 2 diabetes, C-peptide levels will typically be normal or high, as the pancreas works harder to overcome insulin resistance (when the tissues become less sensitive to the effects of insulin) by producing more insulin. (kidshealth.org)
  • C-Peptide is useful in the evaluation of pancreatic beta cell function (e.g., helping distinguish type 1 from type 2 diabetes mellitus, or monitoring patients who have received islet cell or pancreatic transplants) and for determining the source of insulin in patients with hyperinsulinemic hypoglycemia (e.g., distinguishing insulin-secreting tumors from exogenous insulin administration). (questdiagnostics.com)
  • In type 1 diabetes, the pancreas produces little or no insulin and little or no C-peptide. (kidshealth.org)
  • A C-peptide test is not ordered to help diagnose diabetes, but when a person has been newly diagnosed with diabetes, it may be ordered by itself or along with an insulin level to help determine how much insulin a person's pancreas is still producing (endogenous insulin). (labcorp.com)
  • C-peptide levels may be ordered when a person has been newly diagnosed with type 1 diabetes as part of an evaluation of the person's "residual beta cell function. (labcorp.com)
  • Peptides are already effective against bacteria when working "alone" - but in combination with the carrier structure they are even stronger. (empa.ch)
  • Other peptides are studied because they have or may have value in treating diseases such as cancer , AIDS , and other viral and bacterial diseases. (everything2.com)
  • The reason for this lies in their structure, which results in peptides being broken down relatively quickly inside the human body, before they can have an anti-bacterial impact. (empa.ch)
  • Initial tests with bacterial cultures have shown that the peptides are completely enclosed by the nanocarriers and thus remain stable. (empa.ch)
  • Um formulário puro da enzima proteolytic é usado para hydrolyze a proteína para produzir seqüências curtos do peptide. (news-medical.net)
  • Estas bactérias ou o fermento segregam suas enzimas proteolytic em momento oportuno para liberar peptides das proteínas. (news-medical.net)
  • In many metabolic disorder s, the body may inadvertently produce toxic peptides that it cannot break down which build up in the system and damage organs. (everything2.com)
  • Sometimes a C-peptide test may be used to help evaluate a person diagnosed with metabolic syndrome, a set of risk factors that includes abdominal obesity, increased blood glucose and/or insulin resistance, unhealthy blood lipid levels, and high blood pressure (hypertension). (labcorp.com)
  • It is particularly misleading to express results in terms of weight without evidence of homogeneity, because apart from error peptides (which may not be inert), account is seldom taken of salt and solvent content. (nature.com)
  • A peptide chain named humanin has shown some promise in treating Alzheimer's disease by blocking the processes that cause brain cell degeneration in the disease. (everything2.com)
  • Here we show that abacavir can bind within the F pocket of the peptide-binding groove of HLA-B*57:01, thereby altering its specificity. (pnas.org)
  • The tyrosine residue is an important structural motif that is required for the opioid peptide to bind with its corresponding receptor. (news-medical.net)
  • While drawn as a single bond, the peptide bond has partial double bond character that enforces a well-defined flat structure. (encyclopedia.com)
  • These are tumors of the islet cells in the pancreas that can produce uncontrolled amounts of insulin and C-peptide and can cause acute episodes of hypoglycemia. (labcorp.com)