AnatomyOrganismsDiseasesChemicals and DrugsPhenomena and ProcessesTechnology, Industry, Agriculture
Burkholderia malleiGlandersBurkholderiaBurkholderia pseudomalleiBurkholderia InfectionsMalleusMelioidosisBiological Warfare AgentsDourineBurkholderia cepaciaBurkholderia cepacia complexBurkholderia cenocepaciaBacteriaHorsesBacterial ProteinsGenome, Bacterial
GlandersMelioidosisPseudomallei and Burkholderia malleiRelated Gram-negativeBacillusSpeciesGram-negativeATCCInfectionFrancisellaGenomeInfectionsTularemiaYersiniaVirulenceMicrobiologyVirusesInfectious bacteriaPathogenic bacteriaReagentsOrganismsStrainInfectFungiGenusPlague bacteriaDiseasesPathogensChromosomeStrainsBacterialFeverLatinGenesDiseaseBioterrorism agentAntibioticsTypicallyLungsBiological
Glanders16
  • Glanders is caused by infection with the Burkholderia mallei, usually by ingestion of contaminated feed or water. (wikipedia.org)
  • Mallein (ATCvet code: QI05AR01 (WHO)), a protein fraction of the glanders organism (B. mallei), is injected intradermopalpebrally or given by eye drop. (wikipedia.org)
  • Glanders is an infectious disease that is caused by the bacterium Burkholderia mallei . (cdc.gov)
  • Glanders and melioidosis are related diseases produced by bacteria of the Burkholderia species, which are gram-negative rods. (medscape.com)
  • Burkholderia mallei (a nonmotile, nonsporulating, obligate aerobic, gram-negative bacillus) is the causative agent of glanders, which is primarily a disease of animals such as horses, mules, and donkeys. (medscape.com)
  • Glanders is caused by Burkholderia mallei (formerly Pseudomonas mallei ). (medscape.com)
  • The strain, B. mallei BAC 86/19, was obtained from the tracheal secretion of a young mare displaying positive serology but no clinical signs of glanders. (bvsalud.org)
  • Burkholderia mallei is an infectious bacteria associated with Glanders. (wagwalking.com)
  • The exposure to the bacterium Burkholderia mallei is extremely rare due to the successful elimination of Glanders Farcy in most countries worldwide. (wagwalking.com)
  • There are various symptoms associated with Glanders which depend on the path of the infection as it relates to the bacteria or organism. (wagwalking.com)
  • B. mallei is responsible for causing glanders disease, which historically affected mostly animals, such as horses, mules, and donkeys, and rarely humans. (geneticpcr.com)
  • Burkholderia mallei is the causative agent of glanders, it is gram negative, bipolar, aerobic bacterium. (com.pk)
  • A species of gram-negative bacteria parasitic on HORSES and DONKEYS causing GLANDERS , which can be transmitted to humans. (lookformedical.com)
  • The antibiotic injections are due to Gabriel contracting glanders after being exposed to the Burkholderia mallei bacteria that William smuggled out of a US biological weapons lab three episodes ago. (psychodrivein.com)
  • Glanders is a fatal infectious and notifiable zoonotic disease of equines caused by the Gram-negative non-motile bacterium Burkholderia (B.) mallei, which is responsible for chronic suppurative lesions of the skin and mucous membranes, pneumonia and septicemia in equines. (arccjournals.com)
  • The T2Biothreat Panel is a direct-from-blood molecular diagnostic test that runs on the FDA-cleared T2Dx® Instrument and simultaneously detects six biothreat pathogens, including the organisms that cause anthrax ( Bacillus anthracis), tularemia ( Francisella tularensis), glanders ( Burkholderia mallei), melioidosis ( Burkholderia pseudomallei ) , plague ( Yersinia pestis ), and typhus ( Rickettsia prowazekii ). (ozarksfirst.com)
Melioidosis7
  • Due to the high mortality rate in humans and the small number of organisms required to establish infection, B. mallei is regarded as a potential biological warfare or bioterrorism agent, as is the closely related organism, B. pseudomallei, the causative agent of melioidosis. (wikipedia.org)
  • Melioidosis, also known as Whitmore disease, is caused by the bacterium B pseudomallei (a motile, aerobic, non-spore-forming bacillus). (medscape.com)
  • A species of gram-negative, aerobic bacteria that causes MELIOIDOSIS . (lookformedical.com)
  • Burkholderia pseudomallei is the etiological agent of melioidosis and a CDC category B select agent with no available effective vaccine. (edu.au)
  • Infection with the gram-negative bacterium Burkholderia pseudomallei can result in a life-threatening disease known as melioidosis. (health.mil)
  • Melioidosis is a potentially life threatening disease caused by the gram-negative bacterium Burkholderia pseudomallei . (health.mil)
  • This bacterium causes a rare and serious disease called melioidosis. (cdc.gov)
Pseudomallei and Burkholderia mallei2
Related Gram-negative1
  • These diseases are caused by closely related Gram-negative bacteria named Burkholderia (B.) mallei and B. pseudomallei, respectively. (ufl.edu)
Bacillus1
  • Burkholderia mallei is an aerobic, Gram-negative, non-motile bacillus. (bvsalud.org)
Species5
  • About 100 species have been described within genus Burkholderia , which is related to genus Taylorella . (slu.se)
  • The two species of genus Burkholderia , which have beebn included in VetBact, are very closely related. (slu.se)
  • The genes encoding T6SS have been reported a few years ago as being present in different bacterial species, although it was not clear at that time whether those genes act together or are important in bacteria-host interactions [ 7 ]. (biomedcentral.com)
  • In this Opinion, the antimicrobial-resistant bacteria responsible for transmissible diseases that constitute a threat to the health of certain kept fish species have been assessed. (irta.cat)
  • Sero-crossreactivity is common among O-antigens of Burkholderia species. (edu.au)
Gram-negative8
  • The mini-Tn7 vectors are universally applicable in Gram-negative bacteria and thereby facilitate the manipulation of many organisms for which few genetic systems are available. (nau.edu)
  • Burkholderia mallei is a Gram-negative, non-motile, aerobic bacterium belonging to the Burkholderiaceae family. (geneticpcr.com)
  • A genus of gram-negative, aerobic, rod-shaped bacteria. (lookformedical.com)
  • Complex interactions between Gram-negative bacteria and their environment are facilitated by numerous surface-attached and exported macromolecules, some of which represent bacterial toxins and effectors. (biomedcentral.com)
  • Tetracyclines are used principally in the treatment of infections caused by susceptible Rickettsia, Chlamydia, Mycoplasma, and a variety of uncommon gram-negative and gram-positive bacteria. (antiinfectivemeds.com)
  • Because of the development of resistance, tetracyclines are rarely used for the treatment of infections caused by common gram-negative or gram-positive bacteria unless other appropriate anti-infectives are contraindicated or are ineffective and in vitro susceptibility tests indicate that the causative organisms are susceptible to the drugs. (antiinfectivemeds.com)
  • Ehrlichia are gram-negative, obligate intracellular bacteria belonging to the order Rickettsiales and are transmitted by ticks. (laboklin.com)
  • Burkholderia pseudomalle is a gram-negative bacterium and Tier 1 Select Agent that typically lives in soil and water in regions with tropical and subtropical climates around the world, such as South and Southeast Asia, northern Australia, parts of Central and South America, the U.S. Virgin Islands, and Puerto Rico. (cdc.gov)
ATCC1
  • Choi, KH, DeShazer, D & Schweizer, HP 2006, ' mini-Tn7 insertion in bacteria with multiple glmS-linked attTn7 sites: Example Burkholderia mallei ATCC 23344 ', Nature Protocols , vol. 1, no. 1, pp. 162-169. (nau.edu)
Infection12
  • It is caused by infection with the bacterium Burkholderia mallei. (wikipedia.org)
  • No vaccine is licensed for use in the U.S. Infection with these bacteria results in nonspecific symptoms and can be either acute or chronic, impeding rapid diagnosis. (wikipedia.org)
  • This study aims to assess the virulence of a specific B. mallei strain, isolated in Brazil, in BALB/c mice through intranasal infection. (bvsalud.org)
  • B. mallei persisted within the liver and lung for five days post-infection and in the spleen for seven days. (bvsalud.org)
  • It is caused by BURKHOLDERIA PSEUDOMALLEI and may range from a dormant infection to a condition that causes multiple abscesses, pneumonia, and bacteremia. (lookformedical.com)
  • There are six types of infection, depending on where the bacteria entered the human body. (tenzzies.com)
  • The most common form of infection is Ulceroglandular tularemia, when the bacteria enters the human body through the skin. (tenzzies.com)
  • Infection of the lymphatic system develops following contamination of skin wounds by various bacteria, most commonly Corynebacterium pseudotuberculosis (the causative agent of ulcerative lymphangitis/pigeon fever). (uky.edu)
  • Burkholderia mallei infection in a horse imported from Brazil. (arccjournals.com)
  • We report that larvae of the wax moth ( Galleria mellonella ) are susceptible to infection with the human enteropathogen Yersinia pseudotuberculosis at 37 °C. Confocal microscopy demonstrated that in the initial stages of infection the bacteria were taken up into haemocytes. (microbiologyresearch.org)
  • The primary route of infection with B. pseudomallei is believed to be through skin inoculation of the soil-dwelling bacterium. (health.mil)
  • B. pseudomallei isolates from both patients and the environmental samples were all genetically similar and were distinct from previous known isolates, indicating bacteria from the environment was the likely source of infection for both patients and has been present in the area since at least 2020. (cdc.gov)
Francisella1
  • First discovered in 1911 in Tulare, California, this disease is caused by the bacteria Francisella Tularensis. (tenzzies.com)
Genome3
  • His research in Genome tackles topics such as Burkholderia contaminans which are related to areas like Horizontal gene transfer and Antibiotic sensitivity. (research.com)
  • 2004. Structural flexibility in the Burkholderia mallei genome . (umd.edu)
  • The genome of this organism carries many genomic islands as compared to the related organism B. mallei, suggesting extensive horizontal transfer. (up.ac.za)
Infections3
  • This research points to the importance of the continued investigation of the virulence mechanisms and potential countermeasures associated with B. mallei infections, including their Brazilian isolates. (bvsalud.org)
  • Infections with bacteria of the genus BURKHOLDERIA . (lookformedical.com)
  • Examples of bacteria that cause infections include Streptococcus , Staphylococcus , and E. coli . (medlineplus.gov)
Tularemia2
  • Oculoglandular tularemia happens when the bacteria enter the body from the eyes. (tenzzies.com)
  • The most severe and rarest form of the illness is Typhoidal tularemia, which happens when the bacteria attacks multiple organs in the human body. (tenzzies.com)
Yersinia1
  • Plague is a disease caused by Yersinia pestis ( Y. pestis ), a bacterium found in rodents and their fleas in many areas around the world. (cdc.gov)
Virulence1
  • These findings underscore the detectable virulence of the Brazilian B. mallei BAC 86/19 strain in mice, which are relatively resilient hosts. (bvsalud.org)
Microbiology2
Viruses2
  • Bacteria and viruses are everywhere. (tenzzies.com)
  • It is estimated that 50% or less of those individuals infected with enteric viruses or bacteria actually become ill (Haas et al. (scienceopen.com)
Infectious bacteria1
Pathogenic bacteria4
  • F. tularensis is considered to be a serious potential bioterrorist threat because it is one of the most infectious pathogenic bacteria known-inhalation of as few as 10 organisms can cause disease-and it has substantial capacity to cause serious illness and death. (centerforhealthsecurity.org)
  • Throughout my professional career, my main research goal has been to contribute significantly in the field of microbial sciences concentrating on the study of pathogenic bacteria. (uga.edu)
  • Phylogenetic reconstruction based on the core genes showed that lateral transfer of the T6SS is probably its major way of dissemination among pathogenic and non-pathogenic bacteria. (biomedcentral.com)
  • The core of T6SS is composed of 13 proteins, conserved in both pathogenic and non-pathogenic bacteria. (biomedcentral.com)
Reagents1
Organisms1
  • In the following list, the micro-organisms written in italics are bacteria, mycoplasma, rickettsia or fungi. (searates.com)
Strain1
  • Most B. oklahomensis strains expressed a distinct and non-seroreactive O-antigen type, except strain E0147 which expressed O-antigen type A. O-antigen type B2 was also detected in B. thailandensis 82172, B. ubonensis MSMB108, and Burkholderia sp. (edu.au)
Infect3
  • B. mallei is able to infect humans, so it is classed as a zoonotic agent. (wikipedia.org)
  • If bubonic plague is not treated, however, the bacteria can spread through the bloodstream and infect the lungs, causing a secondary case of pneumonic plague. (cdc.gov)
  • 4,5 The bacterium can infect any organ in the body, precipitating a diverse assortment of clinical presentations. (health.mil)
Fungi1
  • A Petri dish (alternatively known as a Petri plate or cell-culture dish ) is a shallow transparent lidded dish that biologists use to hold growth medium in which cells can be cultured , [1] [2] originally, cells of bacteria , fungi and small mosses . (wikipedia.org)
Genus1
Plague bacteria2
Diseases1
  • In this opinion, the antimicrobial-resistant bacteria responsible for transmissible diseases that constitute a threat to the health of pigs have been assessed. (irta.cat)
Pathogens2
  • Together, with their high rate of infectivity by aerosols and resistance to many common antibiotics, both bacteria have been classified as category B priority pathogens by the US NIH and US CDC, which has spurred a dramatic increase in interest in these microorganisms. (wikipedia.org)
  • [ 6 ] Because they are highly infectious by inhalation and resistant to routine antibiotics, both bacteria have been classified as category B priority pathogens by the National Institutes of Health and the Centers for Disease Control and Prevention (CDC). (medscape.com)
Chromosome2
  • B. mallei possesses two glmS genes on chromosome 1 and Tn7 transposes to both sites, although transposition to attTn7-1 associated with glmS1 occurs in more than 90% of the clones examined. (nau.edu)
  • This first chromosome integration system in B. mallei provides an important contribution to the genetic tools emerging for Burkholderia spp. (nau.edu)
Strains1
  • PCR screening of O-antigen biosynthesis genes, phenotypic characterization using SDS-PAGE, and immunoblot analysis showed that majority of B. mallei and B. thailandensis strains contained the typical O-antigen type A. In contrast, most of B. ubonensis and B. thailandensis-like strains expressed the atypical O-antigen types B and B2, respectively. (edu.au)
Bacterial1
  • Penicillin , the first antibiotic, was discovered in 1929 when Alexander Fleming noticed that penicillium mold contaminating a bacterial culture in a Petri dish had killed the bacteria around it. (wikipedia.org)
Fever1
  • A rash or blister develops at the place where the bacteria first infiltrate the body, with fever and swollen lymph nodes following quickly. (tenzzies.com)
Latin1
  • Other terms include Latin: malleus, Spanish: muermo, German: Rotz and Norwegian: snive. (wikipedia.org)
Genes1
  • 176 T6SS loci (encompassing 92 different bacteria) were identified and their comparison revealed that T6SS-encoded genes have a specific conserved genetic organization. (biomedcentral.com)
Disease2
  • While there is no vaccine for this disease yet, antibiotics are usually effective in killing these bacteria if treatment is given on time. (tenzzies.com)
  • Once people have the disease, the bacteria can spread to others who have close contact with them. (cdc.gov)
Bioterrorism agent1
  • Burkholderia mallei belongs to category B as a potential bioterrorism agent according to NIAID. (slu.se)
Antibiotics1
  • Each time you take antibiotics, you increase the chances that bacteria in your body will learn to resist them causing antibiotic resistance . (medlineplus.gov)
Typically1
  • In the human population, Burkholderia mallei typically is found in persons with close and frequent contact with infected animals, such as veterinarians, animal caretakers, abattoir workers, and laboratory personnel. (medscape.com)
Lungs1
  • Pneumonic plague may also occur if a person with bubonic or septicemic plague is untreated and the bacteria spread to the lungs. (cdc.gov)
Biological2
  • B. anthracis was developed by several countries as part of their biological weapons (BW) programs, and autonomous groups have also demonstrated the intent to use the bacterium in acts of terrorism. (centerforhealthsecurity.org)
  • The bacterium was developed into an aerosol biological weapon by several countries in the past. (centerforhealthsecurity.org)