Burgdorferi organisms. Medical search. Frequent questions

Borrelia species in the species complex known to cause Lyme disease are collectively called Borrelia burgdorferi sensu lato (s.l.) not to be confused with the single species in that complex Borrelia burgdorferi sensu stricto which is responsible for nearly all cases of Lyme disease in North America. (wikipedia.org)
For example, B. burgdorferi s.s.'s tick-borne Lyme disease may manifest with arthritis-like symptoms. (wikipedia.org)
14 instances in 1995 when salivary glands from several (deer tick) is the vector of Borrelia burgdorferi , the ticks collected from an individual host were pooled for causative agent of Lyme disease. (cdc.gov)
The Lyme disease spirochete, Borrelia burgdorferi, can be recovered long after initial infection, even from antibiotic-treated patients, indicating that it resists eradication by host defense mechanisms and antibiotics. (nih.gov)
Since B. burgdorferi first infects skin, the possible protective effect of skin fibroblasts from an antibiotic commonly used to treat Lyme disease, ceftriaxone, was examined. (nih.gov)
Ticks from many areas of British Columbia carry Borrelia burgdorferi, the organism that causes Lyme disease. (healthlinkbc.ca)
In areas where Lyme disease is endemic or emerging, vaccinate dogs against Borrelia burgdorferi and reducing the risk of infection through year-round tick control and avoiding areas with ticks. (capcvet.org)
Caused by infection with the spirochetal (helical) bacteria Borrelia burgdorferi, Lyme disease is primarily transmitted to humans , as well as dogs , horses and other domesticated animals, by the bite of infected ticks . (newworldencyclopedia.org)
The Borrelia species known to cause Lyme disease are collectively known as Borrelia burgdorferi sensu lato, and have been found to have greater strain diversity than previously estimated. (newworldencyclopedia.org)
While the initial studies have been done on B. burgdorferi and patients and reservoir hosts from the U.S., we anticipate that assays based on orthologous proteins in other Borrelia species could be implemented in Europe and Asia for Lyme disease on those continents and also for specific assays for antibodies to relapsing fever Borrelia species. (universityofcalifornia.edu)
the black-legged tick (Ixodes scapularis) is responsible for transmission of A. phagocytophilum in the upper Midwest and northeastern U.S. These tick species also transmit the agents of Lyme disease (Borrelia burgdorferi) and babesiosis (Babesia species). (medgadget.com)
The Ixodes scapularis tick in the eastern U.S. and Ixodes pacificus tick in the western U.S. are commonly termed deer ticks, or blacklegged ticks, and can carry Lyme disease caused by Borrelia burgdorferi . (msu.edu)
Currently, the Equine Lyme Multiplex Assay developed by Cornell University can provide some level of certainty about the presence of the organism. (barrelhorsenews.com)
Abstract Lyme disease, the most common vector-borne zoonosis in North America, is caused by the spirochetal pathogen Borrelia burgdorferi. (canlyme.com)
Most cases of Lyme disease in the U.S. are caused by a corkscrew-shaped spirochete called Borrelia burgdorferi. (holtorfmed.com)
As the body continues its assault on the Lyme bacteria - sending immune cells to fight the now-disguised organism - this immune response wreaks havoc in places throughout the body such as the skin, brain, nerves, and joints. (holtorfmed.com)
A vaccine is available to aid in preventing disease caused by Borrelia burgdorferi, the Lyme disease organism, but there are currently no vaccines to protect dogs from ehrlichiosis or anaplasmosis. (vetstreet.com)
Minocycline is used in dogs to treat susceptible bacterial infections and infections caused by Rickettsia, Canine ehrlichiosis (anaplasmosis), Toxoplasma, Borrelia burgdorferi (Lyme disease), Leptospirosis, and Neorickettsia helminthoeca (salmon poisoning). (wedgewoodpharmacy.com)
Minocycline is used in horses to treat susceptible bacterial infections and tick-borne diseases such as Ehrlichia, Anaplasma, and Borrelia burgdorferi (Lyme disease). (wedgewoodpharmacy.com)
The blacklegged tick, Ixodes scapularis, is the vector of Borrelia burgdorferi, the etiological agent that causes Lyme disease in the United States. (usda.gov)
In addition, some experts make the assumption that Borrelia burgdorferi sensu lato is not the only factor to explain this disease, in particular certain persistent forms as the persistent polymorphic syndrome possibly due to a tick bite (SPPT), officially recognized by the French High Authority for Health (HAS) (a governmental institution https://www.has-sante.fr ), and the post-treatment Lyme disease syndrome (PTLDS) (1). (fortuneonline.org)
Lyme disease is caused by bacteria called Borrelia burgdorferi ( B burgdorferi ). (medlineplus.gov)
Lyme Disease, caused by the spirochete Borrelia burgdorferi, is the most common vector-borne disease in the United States and Europe. (bepress.com)
Lyme disease, the most common vector-borne illness in the United States, is a multisystem illness caused by infection with the spirochete Borrelia burgdorferi (see the image below) and the body's immune response to the infection. (medscape.com)
Lyme disease is a multisystemic disorder caused by tick-borne infection of humans or other mammalian hosts with Borrelia burgdorferi. (uth.edu)
In this study, we have identified and characterized an elaborate genetic system in the Lyme disease spirochete B. burgdorferi that promotes extensive antigenic variation of a 34-kDa surface-exposed lipoprotein, VlsE. (uth.edu)
Ethnobotanical plant extracts, including Ghanaian quinine and Japanese knotweed, show strong activity against B.burgdorferi, outperforming current antibiotics for the treatment of Lyme disease. (neurosciencenews.com)
In a new study published in Frontiers in Medicine , researchers from the Johns Hopkins Bloomberg School of Public Health, with colleagues at the California Center for Functional Medicine and Focus Health, surveyed the power of 14 plant-based extracts to kill Borrelia burgdorferi, compared to the currently used Lyme antibiotics doxycycline and cefuroxime. (neurosciencenews.com)
Lyme disease which is caused by the spirochetal bacteria Borrelia burgdorferi s.s. (pearltrees.com)
Lyme arthritis, for example, occurs mainly in infections with B. burgdorferi s. s. (altmeyers.org)

[9] The genome of B. burgdorferi includes a linear chromosome approximately one megabase in size, and 21 plasmids (12 linear and 9 circular)-the largest number of plasmids (double-stranded DNA molecules separate from the chromosomal DNA ) found in any known bacterium [10] . (newworldencyclopedia.org)
Uh, this one over here on the far left is a specific bacterium known as Borrelia burgdorferi. (pearson.com)
But while the body can now see the bacterium, it is unable to effectively attack it, and instead launches a massive inflammatory response that causes damage to the body's tissues rather than killing the organism. (holtorfmed.com)
Once the Borrelia burgdorferi bacterium is in the body, it starts to change its form by altering the proteins on its outer cell wall, effectively hiding itself from the immune system. (holtorfmed.com)
It is caused by the spirochete (corkscrew-shaped) bacterium Borrelia burgdorferi and close relatives and mainly spread through the bite of infected ticks. (neurosciencenews.com)
The researchers tested these extracts' effectiveness in vitro (outside of a living organism) against the free-swimming "planktonic" form of the bacterium as well as against microcolonies. (neurosciencenews.com)
Biology A. Bacterium Borrelia burgdorferi is responsible for Lyme's Disease. (slideserve.com)

Despite the common findings of antibodies reactive to B. burgdorferi in cats in endemic areas, natural disease caused by infection in cats - if it occurs at all - is poorly understood. (capcvet.org)
Infection with B. burgdorferi is common in the northeastern, upper midwestern, and West Coast states. (capcvet.org)
Borrelia burgdorferi infection is more common in areas where tick infestation pressure is high and routine acaricide use is not practiced. (capcvet.org)
This is because of the paucity or absence of organisms in most specimens, even during active infection. (universityofcalifornia.edu)
And, like the attack going on in the rest of the body, these cells continue to ineffectively fight a cloaked organism, damaging the brain while allowing the infection to continue. (holtorfmed.com)
It cannot be excluded at present that maternal infection by Borrelia burgdorferi poses a risk to the unborn. (biomedcentral.com)
During the infection Borrelia burgdorferi migrate into different tissues of the host organism to reach so-called "immune privileged niches" where they are protected from the attack of the immune system. (altmeyers.org)
Functional analysis of the Borrelia burgdorferi bba64 gene product in murine infection via tick infestation. (cdc.gov)

B. burgdorferi sensu stricto (predominant in North America, but also in Europe), B. afzelii, and B. garinii (both predominant in Eurasia). (newworldencyclopedia.org)
At present, diagnostic tests are based only on B. burgdorferi sensu stricto (the only species present in the United States), B. afzelii, and B. garinii. (newworldencyclopedia.org)

One of the most striking features of B. burgdorferi as compared with other bacteria is its unusual genome, which is far more complex than that of its spirochetal cousin Treponema pallidum, the agent of syphilis. (newworldencyclopedia.org)
It is caused by the spirochetal organism Borrelia burgdorferi. (libsyn.com)

In North America, the agent is the spirochete Borrelia burgdorferi . (cdc.gov)

Three main species (Borrelia garinii, Borrelia afzelii, and Borrelia burgdorferi s.s.) are the main causative agents of the disease in humans, while a number of others have been implicated as possibly pathogenic. (wikipedia.org)
Spirochetes similar to B. miyamotoi have recently been found in both Ixodes ricinus ticks in Sweden and I. scapularis ticks in the U.S. As of 2021, the B. burgdorferi s.l. species complex is known to include the following species:(Supp. (wikipedia.org)
Now the second part of this naming system is going to indicate the species of the organism and this second part where the species is always going to have a first letter that is not capitalized. (pearson.com)
OspA serotype 1 corresponds to the species B. burgdorferi s.s. (altmeyers.org)

Minocycline is used in cats to treat susceptible bacterial infections and infections caused by a number of other organisms including Bartonella, Mycoplasma, Dermatophilus, and Mycobacteria. (wedgewoodpharmacy.com)
The virulence of this organism is related to a bacterial constituent that interferes with which of the following host phagocyte functions? (practicetestgeeks.com)
Borrelia burgdorferi , an emerging bacterial pathogen, is maintained in nature by transmission from one vertebrate host to another by ticks. (cdc.gov)

Spirochetes of B. burgdorferi enter connective tissue upon inoculation and thus are not found by microscopy in circulating blood and are only rarely visualized directly in tissue sections from infected dogs. (capcvet.org)
It is effective against a broad spectrum of gram-negative and gram-positive bacteria, and a wide variety of other organisms including Rickettsia, Spirochetes, Mycoplasma, and Chlamydia. (wedgewoodpharmacy.com)

The ability of the organism to survive in the presence of fibroblasts was not related to its infectivity. (nih.gov)
Associated with the loss of plasmids is a loss in the ability of the organism to infect laboratory animals , suggesting that the plasmids encode key genes involved in virulence. (newworldencyclopedia.org)

Like B. garinii, B. burgdorferi is a trigger of neuroborreliosis. (altmeyers.org)

Thirty-three (40.2 %) horseflies were positive for at least one micro-organism. (fortuneonline.org)

However, deer are not known to serve as a source of ticks that transmit B. burgdorferi due to the host preferences of immature I. scapularis and I. pacificus . (capcvet.org)

These abilities serve to establish, multiply and spread the pathogen in the infected organism. (altmeyers.org)

Their mechanism of action is through the inhibition of protein synthesis and the alteration of cytoplasmic membrane permeability within the susceptible organism. (wedgewoodpharmacy.com)

S1) B. afzelii B. americana B. andersonii (proposed) B. bavariensis B. bissettiae B. burgdorferi s.s. (wikipedia.org)

Staphylococcus aureus is the most common organism in children in all age cat-egories. (contemporarypediatrics.com)
But specifically, the Bristol group found an Actinobactor called Propionibacterium acnes ( P. Acnes ) in autopsied AD brains-a common organism, traditional felt to be non-pathogenic and commonly found on our skin which can cause, among other things, acne. (j-alz.com)

In America, this nine months' shift between MS and schizophrenic births is also reflected by the periodicity of Borrelia burgdorferi transmitting Ixodes pacificus ticks along the West Coast and the periodicity of Ixodes scapularis along the East Coast. (biomedcentral.com)

Clinical data have shown that tick-borne diseases caused by Borrelia burgdorferi sensu lato, Bartonella spp. (medscimonit.com)
Serological studies have shown that infections caused by B. burgdorferi sensu lato and Bartonella sp. (medscimonit.com)
Specific antibodies to B. burgdorferi sensu lato and Bartonella sp. (medscimonit.com)
The following micro-organisms were searched for in horseflies, by using real time quantitative polymerase chain reaction (qPCR) : Borrelia burgdorferi sensu lato (sl), Borrelia miyamotoi, Borrelia hermsii, Bartonella spp. (fortuneonline.org)

Genetic exchange, including plasmid transfers, contributes to the pathogenicity of the organism. (newworldencyclopedia.org)

These infectious organisms actually live inside your dog's cells. (dogsnaturallymagazine.com)

Additional B. burgdorferi sensu lato genospecies are suspected of causing illness, but are not confirmed by culture. (newworldencyclopedia.org)
Especially within the human pathogenic genospecies (B. burgdorferi s. s. (altmeyers.org)

that transmit B. burgdorferi are three-host ticks that feed on animals as larvae, nymphs, and adults. (capcvet.org)
The immature larval or nymphs ticks acquire B. burgdorferi from wild rodent when feeding in nature and then transstadially transmit the infections to other hosts after these ticks molt to their subsequent developmental stage(s). (capcvet.org)
ticks that can transmit B. burgdorferi can be identified by the presence of an anal groove arching anterior to the anus (arrow) on the ventral surface of nymphal or adult ticks. (capcvet.org)

My studies revealed that B. burgdorferi possesses a large number of previously undefined regulatory targets, including extended 5' and 3' UTRs of known genes, and encodes several hundred-putative small non-coding RNAs. (uky.edu)
Variation in genes can be used to infer relationships between organisms. (binghamton.edu)
We found that the distributions and frequencies of types of OspC genes differed between populations of B. burgdorferi in the Northeast, the Midwest, and California. (cdc.gov)

In our opinion, assays for antibodies to B. burgdorferi will remain the most common method for laboratory-based diagnosis. (universityofcalifornia.edu)

A 28-kilobase linear plasmid of B. burgdorferi B31 (lp28-1) was found to contain a vmp-like sequence (vls) locus that closely resembles the variable major protein (vmp) system for antigenic variation of relapsing fever organisms. (uth.edu)

First, I sought to better understand the stimuli B. burgdorferi sense in order to adapt to their hosts by testing several hypotheses centered on the general notion that B. burgdorferi senses both internal and external metabolic cues as primary signals for adaptation. (uky.edu)

Now again, within each of these different types of organisms there are going to be different strains. (pearson.com)
If the patient has been in Europe, where different strains of Borrelia are more common, a C6 peptide ELISA is a more accurate confirmatory test than the Western blots, which have been developed to B burgdorferi, which is the strain found in the United States. (medscape.com)
In regions where B. burgdorferi is enzootic, sites as small as a few hectares have between 9 and 15 strains ( 4 - 6 ). (cdc.gov)
The presence of lp28-1 correlates with the high-infectivity phenotype in B. burgdorferi strains tested. (uth.edu)

If an infected tick is able to feed for long enough on a horse, B. burgdorferi travels through most soft tissues and the bloodstream. (barrelhorsenews.com)
Not only can the Borrelia burgdorferi spirochete cloak itself when it enters the body, but it also has a unique inner structure, called a flagellum, that propels the organism through body tissues and thick mucus that typically would stop a bacteria from moving. (holtorfmed.com)

All organisms finely tune gene expression in order to adapt to and survive within their current niche. (uky.edu)
The work in this section focus on the idea that B. burgdorferi gene regulatory networks are extremely complex and are not currently well defined in the literature. (uky.edu)

Nymphs pick up bacteria when they feed on small rodents, such as mice, infected with B burgdorferi . (medlineplus.gov)
Among the reservoirs for B. burgdorferi are rodents, other small mammals, and ground-foraging birds. (cdc.gov)

The researchers show that plant extracts from black walnut, cat's claw, sweet wormwood, Mediterranean rockrose, and Chinese skullcap had strong activity against B. burgdorferi, outperforming both tested antibiotics. (neurosciencenews.com)

Our prospective real time qPCR study has shown that horseflies may harbour several micro-organisms which could be pathogenic for animals and humans. (fortuneonline.org)
At the time, the nat-ur-al leap of a flu direct-ly from poul-try to humans was so improb-a-ble that sci-en-tists first sus-pect-ed that it was the result of con-t-a-m-i-na-tion from Shortridge's lab. (spitfirelist.com)

And so the first part of this latin based naming system indicates the genus of the particular organism, and this first part or the genus of the organism is always going to have a first letter that is capitalized. (pearson.com)

In the absence of fibroblasts, organisms did not survive. (nih.gov)
The absence or rarity of B. burgdorferi in Ohio and in the Rocky Mountain and Great Basin regions suggests that these three populations of B. burgdorferi are geographically if not ecologically isolated. (cdc.gov)

The telomere resolvase encoded by this organism (ResT) promotes the formation of covalently closed hairpin ends on the linear DNA molecules of B. burgdorferi through a two-step transesterification. (canlyme.com)

Vaccines put together the physique's immune system in opposition to the invasion of disease-causing organisms. (sfr-fresh.com)
According to the Centers for Disease Control and Prevention (CDC), the global burden of human anaplasmosis treatment remains high as the organism causes more than 10,000 infections per year worldwide. (medgadget.com)
Try to not squish the tick and get blood on yourself (disease producing organisms may be in the blood) and try to keep the head of the tick attached to the body of the tick. (msu.edu)
When the tick is identified, either at the veterinary clinic or at the laboratory, a tick PCR assay (test code 60065) can be done to detect disease-causing organisms that may be borne by the tick. (msu.edu)

Borrelia burgdorferi sensu lato, Coxiella burnetii, and Rickettsia spp. (medscimonit.com)

B. burgdorferi isn't very destructive, but the patient's immune system may get mixed signals and begin to respond as if the patient is the enemy. (barrelhorsenews.com)
This organism has a unique way of evading the human immune system starting as early as when the tick bite occurs and has learned to survive in the human body even when aggressive treatment attacks are mounted against it. (holtorfmed.com)
This combinatorial form of antigenic variation could potentially yield millions of VlsE variants in the mammalian host, and thereby contribute to immune evasion, long-term survival, and pathogenesis of B. burgdorferi. (uth.edu)
are responsible for the immunogenicity of the Borrelia burgdorferi and for the complex immune response of the host. (altmeyers.org)
Borrelia burgdorferi has the ability of adhesion, invasion, persistence and immune evasion. (altmeyers.org)
2009). Another mechanism of immune evasion is the ability of B. burgdorferi to bind host-specific complement regulators (Reconectin/FHL-1 and Factor H) to the cell surface. (altmeyers.org)

Moreover, the human co-infections with these organisms have occasionally been reported. (medgadget.com)

Detection of Borrelia burgdorferi DNA in tick feces provides evidence for organism shedding during vector feeding. (cdc.gov)

Direct detection of the organism by cultivation, histology of biopsy, or by an approved and validated polymerase chain reaction assay is uncommonly used. (universityofcalifornia.edu)

Many peer-reviewed papers are now in publication which indicate that at least some of the Borrelia organisms can persist through what is deemed adequate antibiotic treatment. (lymediseaseaction.org.uk)

Dogs and cats become infected with B. burgdorferi when feeding ticks inoculate the organisms. (capcvet.org)

Further understanding of the evolution and genetics of its cause, Borrelia burgdorferi , in its environments fosters progress toward ecologically based control efforts. (cdc.gov)

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