Bullous dermatosis. Medical search. Frequent questions

It's essential to differentiate it from diseases like bullous pemphigoid, dermatitis herpetiformis, and epidermolysis bullosa acquisita. (bldgactive.com)
High incidence of autoimmune diseases and potential complications, including the development of lymphoma have been demonstrated in this dermatosis. (scielo.br)
Vesicular and bullous diseases. (aad.org)
Pemphigus vulgaris (PV) and bullous pemphigoid (BP) are the earliest recognized autoimmune blistering diseases, and, together, they account for about one half of the autoimmune blistering diseases. (medscape.com)
This article discusses the oral manifestations of several well-characterized autoimmune blistering diseases, including pemphigus vulgaris, bullous pemphigoid, linear immunoglobulin A (IgA) bullous dermatosis, and paraneoplastic pemphigus (PNP). (medscape.com)
A linear pattern of immunoglobulin and/or complement deposition at the cutaneous basement membrane zone is a characteristic feature in a number of acquired bullous diseases and is occasionally observed in systemic lupus erythematosus. (iacdworld.org)
The differential diagnosis for SJS/TEN includes erythema multiforme (EM), autoimmune bullous diseases (including linear IgA dermatosis), autoimmune disease (including bullous lupus erythematosus), staphylococcal scalded skin syndrome (SSSS), graft-vs-host disease (GVHD), generalized fixed bullous drug eruption, and acute generalized exanthematous pustulosis (AGEP). (clinicaladvisor.com)
We review the pathogenesis, clinical features, diagnosis, differential diagnosis, and therapy of autoimmune bullous skin diseases of childhood, especially of the most common linear IgA dermatosis. (uni-luebeck.de)
In autoimmune bullous diseases, autoantibodies are formed against different adhesion molecules of the skin. (uni-luebeck.de)
Pigmentary disorders were the third families to treat skin diseases in their performed whenever necessary to con- ranking dermatosis (118 cases, 17.8%) children [2], late diagnosis and/or poor firm diagnosis. (who.int)
The term pemphigoid, subdivided into bullous pemphigoid and pemphigoid of mucous membranes (or scarring pemphigoid), is used for bullous cutaneous immunological diseases in which antibodies are produced against subepithelial antigens, leading to the formation of blister below the epithelium and the detachment of the underlying lamina propria. (bvsalud.org)

In cases of linear IgA dermatosis induced by vancomycin, new lesions stop forming within approximately 2 weeks of withdrawal. (medscape.com)
These lesions are vesico-bullous, pruritic, and localized especially on elbows, knees and buttocks, although atypical presentations can occur. (scielo.br)
Extremely rarely, severe IgA bullous disease develops in the neonatal period, and may progress to produce severe mucosal , aerodigestive lesions , and corneal scarring. (dermnetnz.org)
Dermatosis is defined as a disorder involving lesions or eruptions of the skin that are acute (lasting days to weeks) or chronic (lasting months to years). (uspharmacist.com)
1 This article reviews the conditions and treatment of common acute dermatosis lesions. (uspharmacist.com)
While most patients with pemphigus vulgaris have oral lesions, which usually are the first manifestation of this disease, only a few patients with bullous pemphigoid have oral lesions. (medscape.com)
Rarely, bullous and pustular lesions are present as well. (msdmanuals.com)
Diagnosis of acute febrile neutrophilic dermatosis is suggested by the appearance of the lesions and is supported by the presence of associated conditions or drugs. (msdmanuals.com)
The lichen planus, pemphigus vulgaris, and pemphigoid family are the most common dermatoses associated with oral lesions. (bvsalud.org)

Clinical, demographic, and immunohistologic features of vancomycin-induced linear IgA bullous disease of the skin. (medscape.com)

[ 5 ] linear IgA bullous dermatosis (dogs), epidermolysis bullosa acquisita (dogs), and bullous systemic lupus erythematosus (1 dog). (medscape.com)

Acute inflammatory dermatosis conditions include erythema multiforme (EM), pruritus (urticaria), and eczema ( TABLE 1 ). (uspharmacist.com)
Clonazepam has been shown to induce the following dermatologic conditions: lichenoid drug eruption, maculopapular rash, bullous dermatosis, eczematous drug eruption, erythema multiforme, pseudo-mycosis fungoides, localized exfoliating eruptions, and alopecia. (psychiatrist.com)

Acute febrile neutrophilic dermatosis is characterized by tender, indurated, dark-red papules and plaques with prominent edema in the upper dermis and dense infiltrate of neutrophils. (msdmanuals.com)
Acute febrile neutrophilic dermatosis may occur with various disorders. (msdmanuals.com)
Classical acute febrile neutrophilic dermatosis affects mostly women ages 30 to 50, with a female:male ratio of 3:1. (msdmanuals.com)

Also known as linear IgA bullous dermatosis or chronic bullous disease of childhood, LAD causes blisters on the skin and mucous membranes. (autoimmuneinstitute.org)

Researches on DH have shown that it is not just a bullous skin disease, but a cutaneous-intestinal disorder caused by hypersensitivity to gluten. (scielo.br)
Linear IgA bullous disease may present as toxic epidermal necrolysis (TEN) - a severe cutaneous adverse drug reaction with widespread blistering and painful loss of skin. (dermnetnz.org)
2,4 In 1993, consensus-based definitions of severe cutaneous adverse reactions (SCAR) were introduced, noting subgroups of severe bullous skin reactions including SJS, TEN, and SJS/TEN overlap. (clinicaladvisor.com)

Transient acantholytic dermatosis (Grover disease) is a pruritic papular eruption in the seborrheic regions of older men. (logicalimages.com)

Childhood linear IgA disease (also known as "Chronic bullous disease of childhood") is an acquired, self-limited bullous disease that may begin by the time the patient is age 2 to 3 and usually remits by age 13. (wikipedia.org)
It is also called linear IgA bullous dermatosis and in children, it may be known as linear IgA dermatosis of childhood or chronic bullous disease of childhood. (dermnetnz.org)
Genetic involvement may contribute to the development of chronic bullous disease of childhood where a number of human leukocyte antigen types have been linked. (dermnetnz.org)

Linear immunoglobulin (Ig) A dermatosis is an immune-mediated bullous disease characterized by linear deposits of IgA along the basal membrane. (actasdermo.org)
Neutrophilic microabscesses in linear immunoglobulin A (IgA) dermatosis. (medscape.com)

587 Adult linear IgA disease is an acquired, autoimmune blistering disease that may present with a clinical pattern of vesicles indistinguishable from dermatitis herpetiformis, or with vesicles and bullae in a bullous pemphigoid-like appearance. (wikipedia.org)
Dermatitis herpetiformis is an intensely itchy bullous rash characterised clinically by grouped vesicles on an erythematous base. (patient.info)

Welcome to the definitive guide on Linear IgA Bullous Dermatosis (LABD), a complex skin disorder that can be challenging to diagnose and manage. (bldgactive.com)
Linear IgA Bullous Dermatosis, often abbreviated as LABD, is a rare autoimmune skin disorder. (bldgactive.com)
Linear IgA Bullous Dermatosis: The Diagnostic Compass has guided us through the intricate landscape of this rare skin disorder. (bldgactive.com)

The 97 kDa linear IgA bullous disease antigen is identical to a portion of the extracellular domain of the 180 kDa bullous pemphigoid antigen, BPAg2. (medscape.com)
however, rabbit antibodies raised against the recombinant proteins encoded by the gene of mouse bullous pemphigoid antigen 2 (BP180) are capable of inducing blisters in newborn mice in a complement-dependent manner. (medscape.com)

Autoantibodies against BP180, BP20, collagen type VII, desmoglein 1 and 3 and envoplakin can be detected simultaneously using a new multiparameter ELISA profile, considerably facilitating the diagnosis and differentiation of autoimmune bullous dermatoses (AIBD). (clinlabint.com)
Immunohistochemical staining of laminin 332 and collagen IV along the floor of bullae can aid in the diagnosis, although the finding is nonspecific and can be seen in other bullous dermatoses where the schism lies above the lamina densa. (medscape.com)
The dermatosis often precedes the cancer diagnosis. (msdmanuals.com)

Lichen planus is a pruritic inflammatory dermatosis of unknown origin. (thedoctorsdoctor.com)

Neutrophilic eccrine hidradenitis (NEH) is a neutrophilic dermatosis primarily affecting the eccrine glands and occurs most commonly in patients undergoing chemotherapy for a malignancy. (annals.edu.sg)
It is one of a group of autoinflammatory disorders known as neutrophilic dermatoses . (dermnetnz.org)

In 1943 Civatte demonstrated that, in pemphigus, the formation of blisters was intraepidermal, differently from bullous pemphigoid and DH, which present subepidermal alterations. (scielo.br)

Dermatologists play an essential role in this process given the significant incidence of inflammatory dermatoses, as well as skin and soft tissue infections (SSTIs) treated with antibiotics. (skintherapyletter.com)

Linear IgA bullous dermatosis is a rare immune-mediated blistering skin disease frequently associated with medication exposure, especially vancomycin, with men and women being equally affected. (wikipedia.org)
In 1969 Van der Meer, in turn, revealed the occurrence of granular IgA deposits in those same locations, which constituted a major milestone for the understanding of this disease and permitted for the first time its differentiation from linear IgA dermatosis bullosa. (scielo.br)
Who gets linear IgA bullous disease? (dermnetnz.org)
What are the clinical features of linear IgA bullous disease? (dermnetnz.org)
How is linear IgA bullous disease diagnosed? (dermnetnz.org)
The large bullae are consistent with either porphyria cutanea tarda or the bullous disease of dialysis. (medscape.com)
In case an autoimmune bullous disease is suspected, histopathology and immunohistopathology (direct immunofluorescence microscopy) as well as serological tests (indirect immunofluorescence microscopy, ELISA, immunoblot) should be performed. (uni-luebeck.de)

[ 37 ] Particularly severe cases of drug-induced linear IgA dermatosis respond to a short course of oral corticosteroids. (medscape.com)

Let's embark on this journey to demystify Linear IgA Bullous Dermatosis: The Diagnostic Compass. (bldgactive.com)
We report the case of a 60-year-old woman with rheumatoid arthritis being treated with sulfasalazine who developed linear IgA dermatosis and drug rash with eosinophilia and systemic symptoms (DRESS). (actasdermo.org)
This is the first report of sulfasalazine-induced linear IgA dermatosis in association with DRESS and we believe that sulfasalazine should be added to the list of drugs that can cause linear IgA dermatosis. (actasdermo.org)
Approximately 50% of patients with linear IgA dermatosis have detectable circulating antibody that binds to the BMZ. (medscape.com)
Children with linear IgA dermatosis may demonstrate circulating anti-BMZ antibodies more frequently than adults. (medscape.com)
Three cases of linear IgA/IgG bullous dermatosis showing IgA and IgG reactivity with multiple antigens, particularly laminin-332. (medscape.com)
Zenke Y, Nakano T, Eto H, Koga H, Hashimoto T. A case of vancomycin-associated linear IgA bullous dermatosis and IgA antibodies to the a3 subunit of laminin-332. (medscape.com)
Nartker N, Kudlak N, Crowe D. Linear IgA bullous dermatosis protracted by vancomycin-loaded bone cement. (medscape.com)
Drug-induced linear IgA bullous dermatosis in a patient with a vancomycin-impregnated cement spacer. (medscape.com)
Sanke S, Kumar A, Chander R. Linear IgA bullous dermatosis induced by diclofenac sodium. (medscape.com)
Hoffmann J, Hadaschik E, Enk A, Stremmel W, Gauss A. Linear IgA Bullous Dermatosis Secondary to Infliximab Therapy in a Patient with Ulcerative Colitis. (medscape.com)
Large, randomized, placebo-controlled, double-blind studies have not been performed for the treatment of linear IgA dermatosis in children or adults. (medscape.com)
These agents have been shown to be beneficial in the treatment of linear IgA dermatosis. (medscape.com)
Although an antibiotic, tetracycline has proven effective in linear IgA dermatosis, either alone or in conjunction with niacinamide (2 g/d). (medscape.com)
Drug-induced linear IgA bullous dermatosis demonstrating the isomorphic phenomenon. (nih.gov)
It is likely that some cases initially described were of bullous pemphigoid or linear IgA dermatosis bullosa, given the unavailability of better diagnostic tools at that period. (scielo.br)
Autoimmune linear IgA bullous dermatosis and IgA pemphigus are two other good examples [2] [3]. (scirp.org)
Linear IgA bullous dermatitis can be idiopathic or drug-induced. (dermnetnz.org)
These images are a random sampling from a Bing search on the term "Linear IgA Dermatosis. (fpnotebook.com)
Linear IgA bullous dermatosis presents with grouped vesicles and bullae, classically in an annular configuration. (logicalimages.com)
Intertriginous Linear Iga Bullous Dermatosis Treated with Colchicine. (sakkadermatologist.com)

Eczematous dermatoses were the extent, scabies. (who.int)

In clinical evaluation, sensitivities of between 60% (anti-BP230 in bullous pemphigoid) and 100% (anti-desmoglein 3 in pemphigus vulgaris) and specificities of between 97.3% (anti-BP180 NC16A) and 100% (anti-collagen VII) were obtained with sera from patients with different AIBD and negative controls. (clinlabint.com)

For the treatment of corticosteroid-responsive dermatoses other than atopic dermatitis. (pdr.net)

In patients with atypical presentations, additional testing, including bacterial culture and Gram stain of blister fluid to rule out bullous impetigo and Tzanck smear to rule out herpes virus infection, may be helpful. (medscape.com)

The dermatosis and associated symptoms resolved following withdrawal of the drug and treatment with systemic corticosteroids for 2 months. (actasdermo.org)
Describimos el caso de una mujer de 60 años con artritis reumatoide en tratamiento con sulfasalazina, que desarrolló un cuadro de dermatosis IgA lineal con clínica de DRESS (drug-rash with eosinophilia and systemic symptoms) el cual respondió al suspender el fármaco causal más tratamiento con corticoides sistémicos durante dos meses. (actasdermo.org)

Bullous pemphigoid presents with urticarial erythematous plaques and intact, tense bullae in older patients. (logicalimages.com)

Bullous dermatomyositis is a rare variant of dermatomyositis and has been reported in the literature. (annals.edu.sg)

ABSTRACT The prevalence of paediatric dermatoses has risen in Iraq from 33.5% in 1987 to 40.9% in 2010. (who.int)

Anatomy2

Diseases37

Chemicals and Drugs5

Analytical, Diagnostic and Therapeutic Techniques and Equipment1

Diseases11

Lesions9

Vancomycin-induced linear IgA bullous1

Lupus erythematosus1

Erythema2

Acute3

Mucous1

Cutaneous3

Eruption1

Chronic bullous3

Immunoglobulin2

Dermatitis herpetiformis2

Disorder3

Pemphigoid antigen2

Diagnosis3

Pruritic1

Neutrophilic2

Blisters1

Inflammatory1

Disease7

Severe1

Linear21

Eczematous1

Clinical1

Atopic dermatitis1

Impetigo1

Systemic2

Bullae1

Variant1

Prevalence1