Checkpoint Kinase 2DNA DamageCell Cycle ProteinsProtein-Serine-Threonine KinasesAtaxia Telangiectasia Mutated ProteinsProtein KinasesSaccharomyces cerevisiae ProteinsGenes, cdcCell Cycle CheckpointsCell CycleSaccharomyces cerevisiaeDNA, FungalDNA ReplicationS PhaseG2 PhaseYeastsFungal ProteinsNuclear ProteinsDNA-Binding ProteinsMitosisPhosphorylationIntracellular Signaling Peptides and ProteinsUltraviolet RaysSchizosaccharomycesTumor Suppressor ProteinsHydroxyureaSchizosaccharomyces pombe ProteinsDNA RepairMethyl Methanesulfonatecdc25 PhosphatasesSignal TransductionS Phase Cell Cycle CheckpointsM Phase Cell Cycle CheckpointsMutationSpindle ApparatusGenes, FungalGenomic InstabilitySaccharomycetalesCDC2 Protein KinaseNocodazoleSecurinG2 Phase Cell Cycle CheckpointsCyclin BTumor Suppressor Protein p53ExodeoxyribonucleasesGamma RaysG1 PhaseAnaphaseReplication Protein CDNA Breaks, Double-StrandedKinetochoresMolecular Sequence DataChromosomes, FungalGene Expression Regulation, FungalAmino Acid SequenceReplication Protein AHeLa CellsModels, BiologicalNucleic Acid Synthesis InhibitorsRadiation, IonizingChromosomal Proteins, Non-HistoneMad2 ProteinsHistonesTelomereGene DeletionGenome, FungalProtein BindingRecombination, GeneticDNA HelicasesChromatinDose-Response Relationship, RadiationChromosome SegregationCell Line, TumorCaffeineRepressor ProteinsDNAEpistasis, GeneticCyclin-Dependent Kinase Inhibitor p21Base SequenceCarrier ProteinsCell LineCell DivisionCyclin-Dependent KinasesHCT116 CellsMeiosisApoptosisMutagensras-GRF1Recombinational DNA RepairCyclin-Dependent Kinase 2Recombinant Fusion ProteinsRibonucleotide ReductasesCell NucleusEnzyme ActivationCdc20 ProteinsMetaphaseAllelesSequence Homology, Amino AcidTwo-Hybrid System TechniquesTranscription Factors