• Bucladesine is a cyclic nucleotide derivative which mimics the action of endogenous cAMP and is a phosphodiesterase inhibitor. (wikipedia.org)
  • The data showed that bucladesine (300nM/mouse) reduced the seizure latency and threshold. (wikipedia.org)
  • Bucladesine (50-100nM/mouse) showed significant attenuation in the morphine withdrawal syndrome in the wild-type mice. (wikipedia.org)
  • The most commonly used model of Down syndrome, the Ts65Dn (TS) mouse, is trisomic Bucladesine in vivo for most of the region of MMU16 that is homologous to HSA21. (flt-3inhibitors.com)
  • Bucladesine is a cell permeable cAMP analog. (wikipedia.org)
  • The effect of bucladesine as a cAMP analog has been studied on the pentylenetetrazol-induced seizure in the wild-type mice. (wikipedia.org)
  • The add-on of the ester-type polyurethane prepolymer constantly decreased with increasing blending amount Bucladesine order of the polydimethylsiloxane polyurethane prepolymer. (tie-2signaling.com)