Brucella suis. Medical search. Frequent questions

Since brucellosis threatens the food supply and causes undulant fever, Brucella suis and other Brucella species (B. melitensis, B. abortus, B. ovis, B. canis) are recognized as potential agricultural, civilian, and military bioterrorism agents. (wikipedia.org)
The Brucella abortus (rough LPS Brucella) vaccine, developed for bovine brucellosis and licensed by the USDA Animal Plant Health Inspection Service, has shown protection for some swine and is also effective against B. suis infection, but there is currently no approved vaccine for swine brucellosis. (wikipedia.org)
Three types of the bacteria that cause brucellosis - Brucella abortus , Brucella melitensis and Brucella suis - are designated as select agents. (cdc.gov)
We report the complete genome sequence of Brucella abortus field isolate 9-941 and compare it to those of Brucella suis 1330 and Brucella melitensis 16 M. The genomes of these Brucella species are strikingly similar, with nearly identical genetic content and gene organization. (nih.gov)
Several fragments previously identified as unique to either B. suis or B. melitensis were present in the B. abortus genome. (nih.gov)
Even though several fragments were shared between only B. abortus and B. suis, B. abortus shared more fragments and had fewer nucleotide polymorphisms with B. melitensis than B. suis. (nih.gov)
Brucella are gram-negative coccobacilli that commonly infect cows (Brucella abortus), pigs (Brucella suis), goats (Brucella melitensis), and dogs (Brucella canis), along with wild animals such as deer, elk, and moose. (loinc.org)
The main pathogenic species of Brucella are Brucella melitensis, Brucella suis and Brucella abortus. (loinc.org)
Brucella abortus is a species of the genus Brucella. (loinc.org)
Human infections are caused most frequently by B. melitensis, B. suis, and B. abortus, while B. canis causes only rare infections. (loinc.org)
Detection of antibodies to Brucella abortus and Brucella suis, the causative agents of brucellosis, using buffered acidified plate antigen (BAPA). (tamu.edu)
Detection of antibodies to Brucella abortus and Brucella suis, the causative agents of brucellosis, by card agglutination. (tamu.edu)
On May 26-27, 1997, nine persons (a farmer, four veterinary clinicians, and four veterinary students) in Manhattan, Kansas, participated in an attempted vaginal delivery, a cesarean delivery, and a necropsy on a stillborn calf that died because of Brucella abortus infection. (cdc.gov)
small Gram-negative coccobacilli that can infect cattle (infection with B. abortus), goats and sheep (B. melitensis), pigs (B. suis), and dogs (B. canis). (cdc.gov)
Brucella is a genus of Gram-negative coccobacilli, and it groups together several species including Brucella abortus , Brucella melitensis, Brucella canis and Brucella suis. (osmosis.org)
So, B. abortus is transmitted by cattle, B. melitensis is transmitted by small ruminants such as goats and sheep, B. canis is transmitted by dogs and B. suis is transmitted by swine and rodents. (osmosis.org)
Brucella species of greatest one-health relevance in the US include those infecting dogs ( Brucella canis ), swine ( Brucella suis ), and cattle and domestic bison ( Brucella abortus ). (avma.org)
While brucellosis has been eradicated from domestic livestock in the US, its detection in US companion animals ( B canis ) and US wildlife reservoirs ( B suis and B abortus ) and enzootic presence internationally pose a threat to human and animal health, warranting its spotlight on the one-health stage. (avma.org)
To develop an effective bivalent vaccine for swine against these two diseases, a leucine auxotroph of the USDA approved vaccine B. abortus strain RB51 was constructed along with leuB gene complementing plasmid pNS4 to over-express antigens from Brucella and influenza. (vt.edu)
本病主要由流產布氏桿菌（B. abortus）、馬爾他布氏桿菌（B. melitensis）、豬布氏桿菌（B (gov.tw)
Brucella abortus (B. abortus), Brucella melitensis (B. melitensis), and Brucella suis (B. suis) are the most virulent of the brucellae, but the traditional detection methods to distinguish them are time-consuming and require high instrumentation. (bvsalud.org)
The causative organisms of human brucellosis are B. abortus (from cattle), B. melitensis (from sheep and goats), and B. suis (from hogs). (msdmanuals.com)
Finally, people can become infected with Brucella RB51, a strain of B abortus that is used to vaccinate cattle in the United States and other parts of the world. (medscape.com)

Brucella melitensis is a gram-negative coccobacillus bacterium from the Brucellaceae family. (loinc.org)
Similar to B. melitensis, B. suis can cause abortion in pregnant hosts. (loinc.org)
Brucella melitensis is particularly common in the Mediterranean basin and it has also been reported in Africa, India, and Mexico [ 6 ]. (hindawi.com)
The most pathogenic (likely to cause disease) species are B. melitensis and B. suis . (medicinenet.com)
Although not endemic in the US, Brucella melitensis warrants awareness as it poses a risk to international travelers. (avma.org)
Human brucellosis cases are rare in non-endemic countries, such as Germany, where infections are predominantly caused by Brucella melitensis. (bvsalud.org)
Generally, B. melitensis and B. suis are more pathogenic than other Brucella species. (msdmanuals.com)
B. suis and especially B. melitensis are able ment during the period January to July made or where the item(s) were usually to cause human infection [2]. (who.int)

New diseases such as Seoulvirus-infections via kept rats, tick-borne encephalit is infections via ticks, and in animals Brucella canis and Brucella suis have been found in the past few years. (rivm.nl)
The separation of B. canis from B. suis bv 3, however, failed. (biomedcentral.com)
and dogs ( Brucella canis ), among others. (preventingwithexperts.com)
However, B canis and Brucella RB51 won't show up on serology, so culture is needed to confirm the infection. (medscape.com)

Brucella suis is a bacterium that causes swine brucellosis, a zoonosis that affects pigs. (wikipedia.org)
Blood cultures grew Brucella suis exposed to swine brucellosis by temporary movement of biovar 1. (cdc.gov)
Brucellosis (Brucella spp. (visavet.es)
Porcine brucellosis (B. suis biovar 2) results in reproductive problems causing economic losses. (visavet.es)
Brucellosis is a worldwide disease of humans and livestock that is caused by a number of very closely related classical Brucella species in the alpha-2 subdivision of the Proteobacteria. (nih.gov)
When humans come in contact with an infected animal or animal products that are contaminated with Brucella, brucellosis may result. (loinc.org)
Brucellosis is in infectious disease caused by bacteria in the genus Brucella . (medicinenet.com)
None of the exposed persons reported having previously had brucellosis or being unintentionally inoculated with Brucella vaccine. (cdc.gov)
Editorial Note: Brucellosis, also known as 'undulant fever' or 'Bangs disease,' is a systemic infection caused by Brucella sp. (cdc.gov)
Diagnosis and treatment of brucellosis is challenging due to the limitations of diagnostic assays and the tendency of Brucella spp to produce nonspecific, insidious clinical signs and evade antimicrobial therapy, making prevention essential. (avma.org)
Swine brucellosis caused by Brucella suis and swine influenza caused by Influenza A virus affect both domestic and feral swine populations. (vt.edu)
The German National Reference Laboratory for Bovine, Porcine, Ovine and Caprine Brucellosis received a suspected Brucella sp. (bvsalud.org)
Brucella suis, the causative agent of brucellosis, poses a significant public health and animal husbandry threat. (bvsalud.org)
Brucella is the causative agent of brucellosis and can be transmitted to humans through aerosolized particles or contaminated food. (bvsalud.org)
Brucellosis is caused by Brucella species, which are gram-negative bacteria. (msdmanuals.com)
Although brucellosis is mainly a bacterial disease of animals, several species of Brucella bacteria are known to cause disease in humans. (medscape.com)
In the United States, 25%-30% of brucellosis cases are due to B suis and almost all are diagnosed in people who hunt and slaughter feral swine. (medscape.com)

This is important for highly pathogenic bacteria such as Bacillus anthracis, Brucella species, and Francisella tularensis. (rki.de)
Brucellae are Gram-negative, facultative intracellular bacteria that can infect many species of animals and man. (hindawi.com)
Brucella bacteria can enter the human body through mucous membranes, breaks in the skin, the respiratory tract, gastrointestinal tract, and even the conjunctiva . (medicinenet.com)
If animals like sheep, goats, buffalo, cows, or camels are infected with Brucella , the milk they produce is contaminated with the bacteria. (medicinenet.com)
Although this risk is generally associated with people who work in laboratories studying Brucella organisms, it is possible that people working in meat-processing areas could be exposed to the bacteria by inhalation of droplets from contaminated meat (cattle, sheep). (medicinenet.com)
Now, Brucella it's a non-motile bacteria that doesn't form spores. (osmosis.org)
Now, Brucella is a very slow growing bacteria, so colonies usually grow in the solid medium after 6 to 8 weeks of incubation. (osmosis.org)
A commercial biotyping system (Taxa Profile™, Merlin Diagnostika) testing the metabolization of various substrates by bacteria was used to determine if a set of phenotypic features will allow the identification of members of the genus Brucella and their differentiation into species and biovars. (biomedcentral.com)
Based on specific and stable reactions a 96-well " Brucella identification and typing" plate (Micronaut™) was designed and re-tested in 113 Brucella isolates and a couple of closely related bacteria. (biomedcentral.com)

Cattle can also be transiently infected when they share pasture or facilities with infected pigs, and B. suis can be transmitted by cow's milk. (wikipedia.org)
Brucella suis is differentiated into five biovars (strains), where biovars 1-3 infect wild boar and domestic pigs, and biovars 1 and 3 may cause severe diseases in humans. (wikipedia.org)
Brucella suis is a zoonotic illness of feral pigs that additionally impacts pig searching canine, pig hunters, veterinarians and veterinary workers. (tbdb.org)
The outcomes obtained from this research present that B. suis publicity is comparatively frequent in canine which have contact with feral pigs, with one in 10 testing seropositive. (tbdb.org)
Since B. suis is normally found in pigs, wild hog (feral swine) hunters are at risk of becoming infected when they field dress infected pigs. (cdc.gov)
Infected pigs act as carriers of B. suis contributing to its environmental persistence. (visavet.es)
Brucella suis infections in pigs causes chronic inflammatory lesions in the reproductive organs or orchitis and may affect joints and/or other organs. (loinc.org)
Feral pigs are known to carry a number of zoonotic diseases, including Brucella suis, leptospirosis and Q fever. (beefcentral.com)
In Australia the Brucella suis infection is only known to occur in feral pigs, not domestic pigs. (beefcentral.com)

Strains of highly pathogenic Brucella have been considered to be used as a biological weapon because the organisms can be aerosolized and then easily inhaled. (medicinenet.com)

This review will focus on zoonotic considerations for Brucella spp found within the US along with their epidemiology, pathophysiology, clinical presentation, treatment, and control strategies. (avma.org)

[ 7 ] Surprisingly, infection with Brucella species accounts for as many as 10% of laboratory-acquired infections, 24% of laboratory-acquired bacterial infections, and 11% of occupational-exposure deaths in the United States. (medscape.com)
Using commercially available rapid bacterial identification systems such as the API 20 NE ® (BioMerieux, Nürtingen, Germany) which include a restricted number of biochemical tests Brucella spp. (biomedcentral.com)

Ten species are recognized within the genus Brucella . (hindawi.com)
The comprehensive testing of metabolic activity allows cluster analysis within the genus Brucella . (biomedcentral.com)
The aim of our study was to develop a miniaturised semi-automated system for the reliable identification of members of the genus Brucella and the differentiation of its species based on comprehensive metabolic activity testing. (biomedcentral.com)

B. suis biovar 2 infection was confirmed by polymerase chain reaction (PCR). (visavet.es)

infection has largely been eliminated from commercial cattle and swine with aggressive vaccination, there is a significant prevalence of Brucella sp. (bvsalud.org)

Due to their typical metabolic profiles a differentiation of Brucella isolates to the species level could be achieved. (biomedcentral.com)

Human IgG antibody Laboratories manufactures the brucella test done on a dog reagents distributed by Genprice. (iowaodes.com)
ing, headache and generalized bone pain, of other members of the family and the with rising titre of brucella IgG antibody main risk factors. (who.int)
Most clinical diagnostic laboratories are able to run serologic tests, which detect an antibody response to most of the Brucella species. (medscape.com)

B. suis are gram-negative, facultative intracellular coccobacilli and can specifically produce in phagocytic cells. (loinc.org)
Brucella are aerobic, gram-negative coccobacilli. (medicinenet.com)
Brucella is a gram-negative coccobacilli that can infect humans and animals. (osmosis.org)

Brucella suis are differentiated into five strains. (loinc.org)
Against a virulent challenge of B. suis, the candidate vaccine strain over-expressing both SOD and WboA protected mice more significantly than the control group and was also found to be better protective than other candidate vaccine strains over-expressing either SOD and L7/L12 together or SOD alone. (vt.edu)
The biotyping system developed for the identification of Brucella and differentiation of its species and biovars may replace or at least complement time-consuming tube testing especially in case of atypical strains. (biomedcentral.com)
A biotyping assay useful for Brucella identification and species differentiation must consequently be able to identify the rising number of upcoming new species as well as single atypical strains which do not fit within the pre-existing scheme [ 10 , 11 ]. (biomedcentral.com)

Some cases in humans in North America have been traced to pork from hogs infected with B suis . (medscape.com)

The most frequent clinical sign following B. suis infection is abortion in pregnant females, reduced milk production, and infertility. (wikipedia.org)

In conclusion, this dissertation describes the construction of an environmentally safe antigen over-expression platform and successful employment of the system as a candidate vaccine in protecting mice against B. suis challenge. (vt.edu)

This structural characteristic allows for B. suis to interact with lipid rafts on the surface of macrophages to be internalized, and the formed lipid-rich phagosome is able to avoid fusion with lysosomes through this endocytic pathway. (wikipedia.org)
Once inside macrophages, B. suis is able to endure the rapid acidification in the phagosome to pH 4.0-4.5 by expressing metabolism genes mainly for amino acid synthesis. (wikipedia.org)
Because B. suis is facultative and intracellular, and is able to adapt to environmental conditions in macrophages, treatment failure and relapse rates are high. (wikipedia.org)

The main objective of this PhD Thesis has been to explore new aspects of the epidemiology, immune response, and pathology of Brucella infection in domestic and wild animals to implement both diagnosis and control of this disease. (visavet.es)
Phylogeography and epidemiology of Brucella suis biovar 2 in wildlife and domestic swine. (cdc.gov)

Flagellar genes, however, are present in the B. suis genome, but are thought to be cryptic remnants because some were truncated and others were missing crucial components of the flagellar apparatus. (wikipedia.org)

Exposure to most species of Brucella , such as those associated with certain types of animals, could potentially lead to infection. (cdc.gov)

However, Brucella has a few virulence factors that it uses to avoid destruction. (osmosis.org)

Commonly infected animals that are hunted that may contain Brucella are caribou, moose, wild hogs (feral hogs), elk, and bison. (medicinenet.com)

Blood was collected by venepuncture and examined for B. suis antibodies utilizing the Rose Bengal Check (RBT) adopted by a Complement Fixation Check (CFT) in the event that they returned a optimistic RBT. (tbdb.org)

The Brucella Test Done On A Dog reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. (iowaodes.com)

In addition to increasing the probability of correctly identifying the etiology of the patient's illness, good communication is essential for safety, especially when infections due to Francisella tularensis, Brucella spp. (scienceopen.com)

How does Brucella affect livestock production? (preventingwithexperts.com)

however, B. suis is endemic among feral from animals of US origin was in process at the time of this investigation, few had been sequenced. (cdc.gov)

Brucella suis is a Gram-negative, facultative, intracellular coccobacillus, capable of growing and reproducing inside of host cells, specifically phagocytic cells. (wikipedia.org)

Ticks have been suggested as vectors or carriers of Brucella. (visavet.es)
ELISA showed positive results in three wild boars from two areas (28.5%) with any Brucella-positive ticks. (visavet.es)

On the bright side, there are now some modern automated blood culture systems called the Bactec systems, which are more effective and can isolate Brucella after only 1 week. (osmosis.org)
Bacteriological tests and PCR-based diagnostics showed the isolate to be B. suis, but did not yield cohesive results regarding the biovar. (bvsalud.org)
The isolate was found to be B. suis bv. (bvsalud.org)
Based on in silico genotyping it could be excluded that the isolate was identical to one of the B. suis bv. (bvsalud.org)

Here, we analyzed an alr deletion mutant and a complemented strain of Brucella suis S2. (bvsalud.org)
Brucella species and biovars revealed characteristic metabolic profiles and each strain showed an individual pattern. (biomedcentral.com)

In addition, the B. suis gene for nickel transport, nikA, is activated by metal ion deficiency and is expressed once in the phagosome. (wikipedia.org)
However, the role of the alanine racemase (alr) gene, which encodes alanine racemase in Brucella, remains unclear. (bvsalud.org)

Each species of Brucella has distinct risk factors. (medscape.com)

B. suis was diagnosed in sows (n = 1,140) by culture and PCR of vaginal swabs, indirect enzyme-linked immunosorbent assay (ELISA-I), and brucellin skin test. (visavet.es)

A common route of Brucella infection is eating or drinking infected dairy products that have not been pasteurized. (loinc.org)

First, there may be direct contact with infected animals - and the host is different for each Brucella species. (osmosis.org)

Summary: Brucella suis encounters a macrophage, but no oxidative burst occurs. (wikipedia.org)

Organisms9

Diseases1

Chemicals and Drugs1

Phenomena and Processes1

Abortus23

Melitensis8

Canis4

Brucellosis17

Bacteria9

Pigs9

Pathogenic1

Zoonotic1

Bacterial2

Genus3

Biovar 2 Infection1

Cattle1

Isolates1

Antibody3

Coccobacilli3

Strains4

Humans1

Abortion in pregnant1

Vaccine1

Macrophages3

Epidemiology2

Genome1

Exposure1

Virulence factors1

Caribou1

Antibodies1

Serum1

Francisella1

Livestock1

Endemic1

Facultative1

Ticks2

Isolate4

Strain2

Gene2

Risk Factors1

Assay1

Dairy1

Animals1

Oxidative1