AnatomyDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsHealth Care
Carcinoma, Signet Ring CellAdenocarcinoma, MucinousCarcinomaStomach NeoplasmsAppendiceal NeoplasmsCarcinoma, Ductal, BreastUmbilicusBreastImmunohistochemistryCarcinoma, Squamous CellCarcinoma, HepatocellularMicrosatellite InstabilityBreast NeoplasmsAdenocarcinomaGastrectomyNeoplasm StagingRare DiseasesMucinsNeoplasm InvasivenessPrognosisCadherinsCarcinoma in SituProto-Oncogene Proteins B-rafPeritoneal NeoplasmsColorectal NeoplasmsLoss of HeterozygosityPyloric AntrumEndoscopy, GastrointestinalCarcinoma, LobularCarcinoma, Intraductal, Noninfiltratingras ProteinsHistocytochemistryCarcinoma, PapillarySurvival AnalysisTumor Markers, BiologicalMicrosatellite RepeatsBreast DiseasesCell Line, TumorLiver NeoplasmsAlcian BlueMutationReceptors, EstrogenGene Expression Regulation, NeoplasticCarcinoma, Basal CellTumor Cells, CulturedCarcinoma, DuctalLymphatic MetastasisReceptor, erbB-2
AdenocarcinomaMalignantTumorsHistologicalSituEpithelialImmunohistochemistryDuctalAcinic cell carcinomasCutaneousMetastasisCancerPapillary carcinomaOvaryNeoplasmsSquamous cellAcinar Cell CarcinomaLymphomaAssociated with a worse prognosisCytoplasmPoorly differentiatedSmall cell carcHepatocellular carcinomaMucinous carcinomaMetastasesLesionsNeoplastic cellsMorphologySpindle cellTumor cellsStomachClinicopathologicalOvarian carcinomaPrognosisBasement membranePleomorphicPatientsMucinStromaAdenosquamousGlandularSarcomaMucoepidermoidCysticGastrointestinal tractMammaryAdenocarcinomas
Adenocarcinoma8
Malignant14
  • The malignant type is seen predominantly in carcinomas. (wikipedia.org)
  • The NCI Thesaurus identifies the following types of signet ring cell Castration cell, a non-malignant cell arising in the anterior pituitary gland under certain abnormal hormonal conditions. (wikipedia.org)
  • Papillary carcinomas of the breast (PCB), also termed malignant papillary carcinomas of the breast, are rare forms of the breast cancers. (wikipedia.org)
  • More resent reports find that these tumor cells strongly express the estrogen receptor in most cases and that PDCIS with tumor cells that do not express the estrogen receptor generally have a more malignant microscopic histopathology. (wikipedia.org)
  • Red, scaly plaque, microscopically characterized by the spread of malignant cells within the epithelium, occasionally with invasion of underlying dermis. (brainscape.com)
  • By definition, pseudomesotheliomatous carcinoma refers to an epithelial neoplasm that secondarily involves the pleura and encases the lung, thereby simulating the radiologic and macroscopic appearance of malignant mesothelioma. (medscape.com)
  • In HNPCC, a mutation that inactivates an MMR gene leads to the accumulation of cell mutations and greatly increases the likelihood of malignant transformation and cancer. (medscape.com)
  • Gastric carcinoma comprises more than 90% of all gastric malignant tumors. (poznayka.org)
  • Michal M, Skálová A, Simpson RHW, Rychterová V, Leivo I: Clear cell malignant myoepithelioma of the salivary glands. (biopticka.cz)
  • A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. (lookformedical.com)
  • A primary malignant neoplasm of epithelial liver cells. (lookformedical.com)
  • A malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. (lookformedical.com)
  • An anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small ovoid cells with scanty neoplasm. (lookformedical.com)
  • A malignant glandular epithelial neoplasm consisting of secretory cells forming acinar patterns. (nih.gov)
Tumors13
  • The World Health Organization (2019) classified papillary neoplasms (i.e. benign or cancerous tumors) of the breast into 5 types: intraductal papilloma, papillary ductal carcinoma in situ (PDCIS), encapsulated papillary carcinoma (EPC), solid-papillary carcinoma (SPC), and invasive papillary carcinoma (IPC). (wikipedia.org)
  • The identification of PBS tumors may require the input of breast pathologists familiar with papillary lesions of the breast. (wikipedia.org)
  • PDCIS tumors may occur alongside of (non-papillary) ductal carcinoma in situ or EPC tumors. (wikipedia.org)
  • PDCIS tumors with these cells have been termed dimorphic variants of PDCIS. (wikipedia.org)
  • Solitary tumors of the uterus which arise de novo from the mesenchymal cells of the myometrium. (brainscape.com)
  • We performed immunohistochemistry analysis of HNF4A, ER, PR and GCDFP-15 in 126 patients divided into three cohorts: primary breast cancer, primary gastric cancer and both types of tumors. (biomedcentral.com)
  • The stomach followed by colon are the two most common primary tumors to result in ovarian metastases , pursued by the breast, lung, and contralateral ovary. (radiopaedia.org)
  • Krukenberg tumors are metastatic tumors to the ovary that contain well-defined histological characteristics (mucin-secreting "signet ring" cells) and usually originate in the gastrointestinal tract 4 . (radiopaedia.org)
  • There are a variety of metastatic carcinomas to the ovary that can mimic primary ovarian tumors 4 . (radiopaedia.org)
  • The great majority of Krukenberg tumors are signet ring cell carcinomas arising in the stomach. (radiopaedia.org)
  • Stromal tumors of the ovary include germ-cell tumors, sex-cord stromal tumors, and other more rare types. (medscape.com)
  • Skálová A: Cell proliferation in salivary glands and tumors of salivary gland origin. (biopticka.cz)
  • We enrolled 31 patients (17 men and 14 women) with lung cancer ( n = 7), breast cancer ( n = 5), gastric cancer ( n = 5), pancreatic cancer ( n = 3), other cancers ( n = 5), and benign tumors ( n = 6). (snmjournals.org)
Histological4
Situ4
  • The World Health Organization regarded solid papillary carcinoma as having two subtypes: in situ and invasive SPC. (wikipedia.org)
  • It is the most common type of ductal carcinoma in situ diagnosed in men. (wikipedia.org)
  • Extension of lymphoma cells into the glandular epithelium of ducts and lobules may mimic in situ carcinoma or pagetoid spread of carcinoma. (basicmedicalkey.com)
  • carcinoma in situ in the stomach (a state of severe cellular atypia or dysplasia, without invasion across the basement membrane of the glands). (poznayka.org)
Epithelial17
  • PCB develop from the epithelial cells that line the outer surfaces of ducts leading from exocrine glands or organs, blood vessels, or inner surfaces of the cavities in many internal organs. (wikipedia.org)
  • PCB are carcinomas derived from the epithelial cells of mammary gland ducts. (wikipedia.org)
  • The microscopic histopathology of typical PDCIS lesions (refer to adjacent high-power photomicrograph) prepared with a hematoxylin and eosin stain consists of mammary ducts that have papillary fronds (i.e. thin, finger-like or leaf-like structures) lined with one or several layers of neoplastic, columnar-shaped epithelial cells (i.e. tall, narrow cells with their nuclei close to the site of their ductal attachment). (wikipedia.org)
  • Epithelial cells lining the fronds' inner surfaces commonly form solid, cribriform (i.e. large nests of cells perforated by many rounded, variably sized spaces), or micro-papillary patterns. (wikipedia.org)
  • There may be a second population of epithelial cells lining the papillae that have abundant clear cytoplasm in addition to the usual neoplastic epithelial cells which line the papillae. (wikipedia.org)
  • Strong GATA3 positivity in all epithelial cells. (ms-validatedantibodies.com)
  • Moderate to strong GATA3 positivity of a epithelial cells. (ms-validatedantibodies.com)
  • Variable (weak to strong) GATA3 positivity in squamous epithelial cells. (ms-validatedantibodies.com)
  • Weak to moderate GATA3 positivity in epithelial cells including hair follicles. (ms-validatedantibodies.com)
  • Synovial sarcomas encompass both biphasic (epithelial and spindle cell components) and monophasic (purely spindle cell) variants. (medscape.com)
  • Signet ring cell lymphoma bears a striking resemblance to signet ring cell lobular carcinoma, and it may require immunostains for lymphoid and epithelial markers to distinguish between these entities. (basicmedicalkey.com)
  • Primary lesions include epithelial ovarian carcinoma (70% of all ovarian malignancies). (medscape.com)
  • Since E-cadherin is a causative event in HDGC and the major epithelial cell adhesion molecule, our goal is to determine the impact of E-cadherin dysfunction in nuclei of HDGC cells during cancer invasion. (nostomachforcancer.org)
  • A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. (lookformedical.com)
  • It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. (lookformedical.com)
  • It represents a large group of epithelial lung malignancies which can be divided into two clinical groups: SMALL CELL LUNG CANCER and NON-SMALL-CELL LUNG CARCINOMA . (lookformedical.com)
  • Rat Muc4, a homologue of human MUC4, has been extensively studied in mammary gland tumours and has been shown to play an important role in epithelial growth, cell differentiation, cell-cell adhesion, metastasis, and tumour apoptosis. (bmj.com)
Immunohistochemistry3
Ductal6
Acinic cell carcinomas1
  • Skálová A, Leivo I, Boguslawsky K, Saksela E: Cell proliferation correlates with prognosis in acinic cell carcinomas of salivary gland origin. (biopticka.cz)
Cutaneous4
  • Yes, well done, this is primary cutaneous signet-ring cell / histiocytoid carcinoma. (dermpathpro.com)
  • 1 ] Breast carcinoma is the most common cause of cutaneous metastasis, followed by carcinoma large intestine, lung, and ovaries in women. (lww.com)
  • Nelson R, Luu L, Silberstein P, Velagapudi M, Huerter C. Novel treatment of locally advanced cutaneous squamous cell carcinoma with cemiplimab: a case report. (creighton.edu)
  • Primary cutaneous signet-ring cell melanoma: a clinico-pathologic and immunohistochemical research of two circumstances Am J Dermatopathol. (ehd.org)
Metastasis4
  • HNF4A alone could be a gold standard marker for distinguishing primary gastric cancer from breast metastasis, thus validating its potential clinical use, especially in populations with high genetic diversity. (biomedcentral.com)
  • The main differential diagnosis is the bladder involvement by lymphoma-plasmocytoma or metastasis from lobular breast cancer or diffuse gastric cancer. (biomedcentral.com)
  • Our results demonstrate that tumor growth, peritoneal dissemination and peritoneum or organ metastasis implanted MKN45 cells were significantly decreased in shAhR and Biseugenol-treated mice and that endoplasmic reticulum (ER) stress was caused. (oncotarget.com)
  • The patient had recently been diagnosed with signet-ring-cell carcinoma of the stomach with evidence of metastasis to the lung and peritoneum and multiple thoracic and abdominal lymph nodes. (cdc.gov)
Cancer35
  • Signet ring cells are most frequently associated with stomach cancer, but can arise from any number of tissues including the prostate, bladder, gallbladder, breast, colon, ovarian stroma and testis. (wikipedia.org)
  • A signet ring-like foamy macrophage, which may mimic a cancer cell, but the texture of the nucleus is similar to that of a normal macrophage. (wikipedia.org)
  • Signet ring cell carcinoma Cancer Research UK. (wikipedia.org)
  • Signet Ring Cancer. (wikipedia.org)
  • Signet ring cell definition - cancer.gov. (wikipedia.org)
  • Signet ring cell cancer information - sites.google.com/site/signetringcancer. (wikipedia.org)
  • GATA3 is frequently found mutated in breast cancer, and downregulation of the protein has been linked to poor prognosis of the disease. (ms-validatedantibodies.com)
  • In the present study, it was shown that metformin reduced cell viability, invasion, migration, and EMT, and induced apoptosis and cell cycle G1 phase arrest in thyroid cancer. (bvsalud.org)
  • Transcriptome analysis demonstrated that the differentially expressed genes induced by metformin were involved in several signaling pathways including apoptosis singling pathways, TGF-ß signaling, and cell cycle regulation in human thyroid cancer cell lines. (bvsalud.org)
  • In addition, the helicase activity of the CDC45-MCM2-7-GINS complex and DNA replication related genes such as RPA2, RAD51, and PCNA were downregulated in metformin-treated thyroid cancer cells. (bvsalud.org)
  • An example of this challenge is distinguishing gastric metastases originating from breast cancer from a gastric primary tumor. (biomedcentral.com)
  • Breast cancer (BC) represents the major cause of cancer-related death among women. (biomedcentral.com)
  • Pretherapy Ferumoxytol-enhanced MRI for Metastatic Breast Cancer: A New Approach for Predicting Tumor Delivery of Macromolecular Therapeutics? (stanford.edu)
  • Distant spread from breast cancer is commonly found in bones, lungs, liver and central nervous system. (biomedcentral.com)
  • We report the case of a 67 year-old-woman who presented with gastrointestinal symptoms which revealed to be the clinical manifestations of peritoneal and retroperitoneal metastatic spread of an invasive lobular breast cancer diagnosed 15 years before. (biomedcentral.com)
  • To the best of our knowledge, the case presented is the third one reported in literature showing a wide peritoneal and extraperitoneal diffusion of an invasive lobular breast cancer. (biomedcentral.com)
  • Androgen receptor (AR) is one of the predominant nuclear hormone receptors in invasive breast cancer and can be explored as a biomarker of response for targeted anti-androgen therapy, especially in the setting of triple negative breast cancer (TNBC). (ecancer.org)
  • Breast cancer has been identified as a heterogeneous disease with marked differences in morphology, molecular biology, clinical findings and outcome [ 1 , 2 ]. (ecancer.org)
  • Triple negative breast cancer (TNBC) is defined by the absence of expression for oestrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor-2 (HER2) which has limited targeted therapeutic options. (ecancer.org)
  • TNBC cases are generally treated by surgery, chemotherapy and carry a poor prognosis when compared with luminal breast cancer. (ecancer.org)
  • TNBC accounts for 170,000 cases of the global breast cancer burden and has been associated with disparities in racial incidence [ 3 ]. (ecancer.org)
  • P. D. Pharoah, P. Guilford and C. Caldas, "Incidence of Gastric Cancer and Breast Cancer in CDH1 (E-Cadherin) Mutation Carriers from Hereditary Diffuse Gastric Cancer Families," Gastroenterology, Vol. 121, No. 6, 2001, pp. 1348-1353. (scirp.org)
  • Development of an Artificial Intelligence-Based Breast Cancer Detection Model by Combining Mammograms and Medical Health Records. (cdc.gov)
  • Ganti AK, Subbiah SP, Kessinger A, Gonsalves WI, Silberstein PT, Lobriza FR Jr. Association between Race and Survival of Patients with Non-Small Cell Lung Cancer in The United States Veterans Affairs Population:Clinical Lung Cancer-2014 Mar;15(2):152-8. (creighton.edu)
  • Gootee J, Patel M, Aurit S, Silberstein P. The importance of adjuvant treatment and primary anatomical site in head and neck basaloid squamous cell carcinoma survival: an analysis of the National Cancer Database. (creighton.edu)
  • Stem Cells and Cancer. (iiarjournals.org)
  • Breast Cancer in the Post-Genomic Era. (iiarjournals.org)
  • Early gastric carcinoma is the term used to describe cancer limited to the mucosa and submucosa. (poznayka.org)
  • This project involves a team of researchers with expertise in cancer genetics (Raquel Seruca), cell biology (Joana Figueiredo), pathology (Fatima Carneiro), and image analysis (João Sanches) from i3S and ISR/IST, in collaboration with members from the International Gastric Cancer Linkage Consortium. (nostomachforcancer.org)
  • Mutations in the CDH1 gene are a frequent cause of hereditary diffuse gastric cancer syndrome (HDGC), which is associated with both gastric and lobular breast cancers at an early age. (nostomachforcancer.org)
  • However, what happens to stomach cells after they have lost CDH1 and begin to form cancer is unknown. (nostomachforcancer.org)
  • To find better stomach cancer treatments, we must understand why and how these early cancer cells form. (nostomachforcancer.org)
  • Our research aims to fully characterize the signet ring cancer cells found in the stomachs of patients with CDH1 mutation who have had total prophylactic gastrectomy. (nostomachforcancer.org)
  • The term "oncotarget" encompasses all molecules, pathways, cellular functions, cell types, and even tissues that can be viewed as targets relevant to cancer as well as other diseases. (oncotarget.com)
  • Pantomics Array Description: IHC control array containing 4 breast cancer cases of strong, moderate, low and negative HER2 breast cancer expressers in. (delos.info)
Papillary carcinoma1
  • Information on the frequency and clinical features of PDCIS is limited since it and EPC were regarded as the same lesion termed intracystic papillary carcinoma until 2012. (wikipedia.org)
Ovary2
  • Krukenberg tumor , also known as carcinoma mucocellulare , refers to the "signet ring" subtype of metastatic tumor to the ovary . (radiopaedia.org)
  • An enlarged ovary with a papillary serous carcinoma on the surface. (medscape.com)
Neoplasms2
  • SFTs of the pleura are localized mesenchymal neoplasms composed of fibroblastlike cells believed to arise from the subpleural connective tissue. (medscape.com)
  • Aberrant (upregulated) expression of the MUC1 mucin has been seen in breast carcinomas and other neoplasms, such as colon and pancreatic cancers. (bmj.com)
Squamous cell3
  • 3. Squamous-cell carcinoma. (poznayka.org)
  • Skálová A, Michal M: Patterns of cell proliferation in actinic keratoacanthomas and squamous cell carcinomas of the skin. (biopticka.cz)
  • Metastatic Squamous Cell Carcinoma in Cerebrospinal Fluid: Why a Rare Diagnosis on Cytology? (karger.com)
Acinar Cell Carcinoma3
  • Prognostic Assessment and Risk Stratification in Patients With Postoperative Major Salivary Acinar Cell Carcinoma. (nih.gov)
  • Metastatic Acinar Cell Carcinoma of the Pancreas: A Retrospective Cohort Study on Systemic Chemotherapy and Review of the Literature. (nih.gov)
  • Acinar cell carcinoma: a report of 19 cases with a brief review of the literature. (nih.gov)
Lymphoma7
  • The diagnosis of primary mammary lymphoma is limited to patients without evidence of systemic lymphoma or leukemia at the time that the breast lesion is detected ( 1 ). (basicmedicalkey.com)
  • The occurrence of synchronous and metachronous lymphoma and breast carcinoma has been described ( 3 ). (basicmedicalkey.com)
  • In one instance, occult low grade non-Hodgkin lymphoma was found in a mastectomy specimen after the operation was performed for intraductal carcinoma ( 4 ). (basicmedicalkey.com)
  • The majority of mammary lymphomas are of the B-cell type, with infrequent examples of T-cell and histiocytic lymphoma described ( 10 , 13 , 14 , 15 , 16 , 17 , 18 ). (basicmedicalkey.com)
  • Lymphoma in the breast typically consists of a dense population of tumor cells that diffusely infiltrate the mammary parenchyma. (basicmedicalkey.com)
  • The needle core biopsy specimen shown here revealed diffuse large cell B-cell lymphoma. (basicmedicalkey.com)
  • The appearance of lymphoma involving mammary stroma that is altered by pseudoangiomatous stromal hyperplasia may also be mistaken for invasive carcinoma ( 13 , 14 ). (basicmedicalkey.com)
Associated with a worse prognosis2
  • A significant number of signet ring cells, generally, are associated with a worse prognosis. (wikipedia.org)
  • 1, 2 Most studies of MUC1 expression in breast carcinomas have shown that increased membrane MUC1 mucin expression on the apical cell surface is associated with a better prognosis (reviewed in Rahn and colleagues 2 ), whereas circumferential staining in tumour cell cytoplasm is associated with a worse prognosis. (bmj.com)
Cytoplasm4
  • High magnification micrograph showing signet ring cells, with clear cytoplasm, in metastatic breast carcinoma. (wikipedia.org)
  • As a dermatopathologist, it is useful to have a list of differentials of tumours presenting in the skin which may show signet-ring cell morphology i.e. large pale or eosinophilic cytoplasm with inclusion or vacuole which compresses the nucleus to the edge of the cell. (dermpathpro.com)
  • The cytoplasm is moderate to abundant and eosinophilic, resembling plasma cells. (biomedcentral.com)
  • The stroma may present a myxoid appearance, and cytoplasm vacuoles can be seen, but true signet cells are not identified (Fig. 3 ). (biomedcentral.com)
Poorly differentiated3
Small cell carc1
  • Around half of them are pure, but conventional UC, sarcomatoid, micropapillary, nested and small cell carcinoma can also be identified. (biomedcentral.com)
Hepatocellular carcinoma2
  • Quality of radiomics for predicting microvascular invasion in hepatocellular carcinoma: a systematic review. (cdc.gov)
  • Predictive Model of Liver Toxicity to Aid the Personalized Selection of Proton vs Photon Therapy in Hepatocellular Carcinoma. (cdc.gov)
Mucinous carcinoma1
Metastases1
Lesions3
  • They are a clinically, histologically, and biologically heterogeneous group of breast cancers that are often difficult to distinguish from each other as well as from other papillary breast lesions. (wikipedia.org)
  • Artificial intelligence breast ultrasound and handheld ultrasound in the BI-RADS categorization of breast lesions: A pilot head to head comparison study in screening program. (cdc.gov)
  • Macroscopically, the lesions of early gastric carcinoma may have 3 patterns-superficial, polypoid and ulcer-associated. (poznayka.org)
Neoplastic cells1
Morphology2
  • From a morphology point of view, in addition to the signet-ring cells, other features include the 'stack of pennies' arrangement (see image annotation below). (dermpathpro.com)
  • Those invasive cells' phenotypic singularity is their abnormal nuclear position and morphology, known as signet ring cell features. (nostomachforcancer.org)
Spindle cell1
  • DSRCT is composed of small cells with round hyperchromatic nuclei and a dense fibrous or spindle cell stroma. (medscape.com)
Tumor cells5
  • An Immunohistochemical study conducted in 2009 of 54 individuals diagnosed with PDCIS found that the tumor cells in 34, 31, and 35 cases, respectively, expressed the estrogen receptor, progesterone receptor, and HER2/neu protein. (wikipedia.org)
  • Tumor cells are small to medium size, discohesive with eccentrically placed oval to round, and hyperchromatic nuclei. (biomedcentral.com)
  • carcinoma contains abundant pools of mucin in which are seen a small number of tumor cells, sometimes having signet-ring appearance. (poznayka.org)
  • A lesion with cytological characteristics associated with invasive carcinoma but the tumor cells are confined to the epithelium of origin, without invasion of the basement membrane. (lookformedical.com)
  • A cell line derived from cultured tumor cells. (lookformedical.com)
Stomach1
  • HDGC seems to occur when the normal CDH1 gene is not present in the cells that line the inside of the stomach. (nostomachforcancer.org)
Clinicopathological2
  • This study investigated the correlations between aberrant expression of mucins in gastric carcinoma and patient clinicopathological features. (bmj.com)
  • The expression of MUC1, MUC2, MUC3, MUC5AC, and MUC6 was investigated immunohistochemically in gastric carcinoma (n = 46) in relation to patient clinicopathological features. (bmj.com)
Ovarian carcinoma2
  • CT appearances can be indistinguishable from primary ovarian carcinoma 2 . (radiopaedia.org)
  • Differentiation between primary and metastatic ovarian carcinoma is of great importance with respect to treatment and prognosis but may be very difficult based on imaging findings solely. (radiopaedia.org)
Prognosis2
  • Patients with low-grade appendiceal mucinous carcinomas (LAMNs) treated with cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) have a favorable prognosis. (rare-cancer.org)
  • These carcinomas are typically unresponsive to adjuvant therapy and are associated with high relapse rates, resulting in a very poor prognosis. (nostomachforcancer.org)
Basement membrane1
Pleomorphic1
  • The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. (lookformedical.com)
Patients1
  • 1982) The importance of MUC1 cellular localization in patients with breast carcinoma: an immunohistologic study of 71 patients and review of the literature . (breast-cancer.ca)
Mucin4
  • They contain a large amount of mucin, which pushes the nucleus to the cell periphery. (wikipedia.org)
  • The pool of mucin in a signet ring cell mimics the appearance of a finger hole and the nucleus mimics the appearance of the face of the ring in profile. (wikipedia.org)
  • and 5) the presence of signet ring-shaped cells bearing mucin-containing granules. (wikipedia.org)
  • Several studies have reported conflicting and inconclusive results concerning the clinical relevance of mucin expression in gastric carcinoma. (bmj.com)
Stroma1
  • Signet ring cells scatter in the ovarian stroma with abundant collagen formation or marked edema. (radiopaedia.org)
Adenosquamous1
Glandular1
Sarcoma1
Mucoepidermoid1
  • Skálová A, Lehtonen H, Boguslawsky K, Leivo I: Prognostic significance of cell proliferation in mucoepidermoid carcinomas of salivary gland. (biopticka.cz)
Cystic1
  • Triglycerides and atherogenic dyslipidaemia: Extending treatment beyond statins in diabetes mellitus on development have not yet been assessed by an independent interviewer such as secondary sample size and shape of a cell or a thiazide-type diuretic triple therapy: Ace inhibitor, thiazide-type diuretic, with an occasional cystic component lined with hobnail cuboidal cells with marked decrease after weaning, characterized by alternating periods of controlled drugs and harm of medicines. (familytreecounseling.com)
Gastrointestinal tract2
  • Tot T. (200) The role of cytokeratins 20 and 7 and estrogen receptor analysis in separation of metastatic lobular carcinoma of the breast and metastatic signet ring cell carcinoma of the gastrointestinal tract . (breast-cancer.ca)
  • Also the pattern of metastatic spread differs significantly between these 2 kinds of breast tumours, with a more common occurrence of unusual location of distant neoplastic foci, especially in the gastrointestinal tract, the genitourinary system and the peritoneum or retroperitoneum, secondary to ILC. (biomedcentral.com)
Mammary2
  • The largest subgroup of primary mammary lymphomas has been described as diffuse histiocytic when classified by the Rappaport system ( 1 , 5 , 6 , 8 ) or as diffuse large cell ( 13 ) ( Fig. 24.1 ). (basicmedicalkey.com)
  • The extra-abdominal form is rare and desmoids of the breast may arise in the mammary gland or may occur as an extension of a lesion arising from the muscles of the chest wall. (wikipedia.org)
Adenocarcinomas1
  • Microscopically, fungating or polypoid carcinomas are well-differentiated adenocarcinomas, commonly papillary type. (poznayka.org)