Clinical trials have shown that patients with prostate, lung, and basal cell carcinoma have benefited from treatment with itraconazole, and there are additional reports of activity in leukaemia, ovarian, breast, and pancreatic cancers. (ecancer.org)
Most - though not all - breast cancers in men appear near the nipple as firm lumps. (boldbeanies.com)
BACKGROUND: To characterize the clinico-pathological features including estrogen receptor (ER), progesterone receptor (PR) and Her-2/neu (HER2) expression in breast cancers in Botswana, and to compare them by HIV status. (bvsalud.org)
Symptoms1
they were interviewed to see what they knew about breast cancer, signs or symptoms, if they had read any material prior to their screening or how they could help prevent breast cancer from occurring. (wikipedia.org)
Trials1
Through its Repurposing Grants for the Rest of the World (ReGRoW) initiative, which provides grants to researchers in low- and lower-middle income countries for clinical repurposing trials, Cures Within Reach is expanding funded trials in India to include oncology trials. (whitehouse.gov)
Diagnosis6
Charise Isis aims to capture 800 portraits - one for every breast cancer diagnosis the U.S. records each day. (whyy.org)
Isis is working to create 800 such portraits for The Grace Project - one for every breast cancer diagnosis the United States records each day. (whyy.org)
The project takes a women-centered approach to improve cancer awareness-by integrating secondary prevention of cervical cancer and breast cancer screening at the primary health care level and linking to facilities to ease additional diagnosis and management steps. (whitehouse.gov)
Breast cancer diagnosis and treatment is influenced by different cultural backgrounds. (wikipedia.org)
Even with the high incidence, there has been a lack of emphasis on diagnosis and detection of breast cancer in its early stages. (wikipedia.org)
Detection2
This is not related to breast cancer but can make the detection of a lump during physical examination harder. (boldbeanies.com)
In Western countries, there are many resources available for patient education and awareness of breast cancer detection as well as many therapeutic options. (wikipedia.org)
Patients6
The photos Charise Isis captured of patients living with breast cancer at the Marie Coffin Gardens in Wilmington, Delaware, look different from what is often the norm: clinical, taken in harsh lighting, and with models cropped out above the neck. (whyy.org)
Smith launched a nonprofit that supports breast cancer patients through mentorship, beauty tutorials, diet tips, and a series of five books featuring candid survivor stories. (whyy.org)
Cures Within Reach will work with other nonprofits and nongovernmental organizations to expand capacity for clinical research in India and identify repurposed therapies for patients with unmet medical needs. (whitehouse.gov)
This is despite the fact that the incidence of breast cancer in China was approximately 215,600 patients in 2011, which compares closely to the incidence in the United States of America. (wikipedia.org)
In China, the majority of breast cancer patients are diagnosed with Stage III/IV disease, which contrasts with Western countries, where patients are more likely to be diagnosed in the early stages. (wikipedia.org)
In China, only about 40% of metastatic breast cancer patients who receive first-line therapy will go on to receive a second line of therapy. (wikipedia.org)
Women4
The 24 models - men and women from age 28 to 68 - are all part of the local breast cancer peer support group In This Together Philly Wilmington and from throughout the tri-state area. (whyy.org)
In studies it shows there is a positive correlation with religion or spirituality and women with breast cancer. (wikipedia.org)
Women need to have access to material and resources to inform them about the importance of screenings and basic facts about breast cancer. (wikipedia.org)
1956). The anatomical approach to the study breast cancer in young adult women. (who.int)
Action1
The evidence for these anticancer effects, in vitro , in vivo , and clinical are summarised, and the putative mechanisms of their action outlined. (ecancer.org)
Treatment3
However, the earlier breast cancer is found, the better the chance of successful treatment, so it's important to look out for any unusual changes and get them checked by your doctor right away. (boldbeanies.com)
This is important because if you do have breast cancer, you can begin treatment right away, which gives you the best possible chance of successful treatment. (boldbeanies.com)
Breast cancer is a particularly good market to highlight the differences in the treatment practices between Western countries and China. (wikipedia.org)
Made2
Given the evidence presented, a case is made that itraconazole warrants further clinical investigation as an anti- cancer agent. (ecancer.org)
RESULTS: A total of 384 unique breast cancer reports met our inclusion criteria. (bvsalud.org)
Highlight1
Ultimately, she hopes to print all 800 portraits on silk banners and display them in a single exhibition to highlight the daily impact of breast cancer in the U.S. (whyy.org)
Common2
Itraconazole, a common triazole anti-fungal drug in widespread clinical use, has evidence of clinical activity that is of interest in oncology. (ecancer.org)
Men and boys can sometimes develop more breast tissue than normal due to a relatively common condition called gynaecomastia. (boldbeanies.com)
Metastatic3
Another area that chemists are tackling is metastatic cancer and the perinuceolar compartments (PNCs), subnuclear bodies that are increased in metastatic cell lines such as breast, colorectal, and ovarian cancers. (nih.gov)
It could reduce PNC prevalence and kill metastatic cancer cells-including lung, liver, pancreatic, prostate, and breast cancer-in mice. (nih.gov)
In China, only about 40% of metastatic breast cancer patients who receive first-line therapy will go on to receive a second line of therapy. (wikipedia.org)
Lung cancer7
A clinical scenario that is not infrequently encountered is an incidental finding of secondary lung cancer of unknown origin, known as adenocarcinoma of unknown primary (ACUP), when patients are undergoing screening chest radiography, computed tomography (CT), or positron emission tomography (PET) with CT. (medscape.com)
Since the introduction of CT in the 1970s, remarkable advances have been made not only in clinicians' ability to diagnose lung cancer but, more important, in clinical staging. (medscape.com)
Listening sessions and interviews were scheduled on the basis of participant preference and consisted of a brief review of maps illustrating the breast and lung cancer burden across Wisconsin, and a semistructured set of questions regarding causes, solutions, and opportunities. (cdc.gov)
See Small Cell Lung Cancer: Beating the Spread , a Critical Images slideshow, to help identify the key clinical and biologic characteristics of small cell lung cancer, the staging criteria, and the common sites of spread. (medscape.com)
Also see the Clinical Presentations of Lung Cancer: Slideshow and Lung Cancer Staging -- Radiologic Options slideshows for additional information on SCLC staging and treatment. (medscape.com)
Lung cancer overall is the second most common malignancy in both sexes in the United States, exceeded in frequency only by prostate cancer in men and breast cancer in women. (medscape.com)
Although less than half as many new cases of lung cancer than breast cancer are diagnosed in US women each year, almost twice as many US women die of lung cancer each year than from breast cancer. (medscape.com)
Pancreatic1
Low CoQ10 levels have also been detected in people with certain types of cancer, 10 including lung, breast and pancreatic cancer, as well as melanoma metastasis, further strengthening the metabolic theory of cancer. (onedaymd.com)
Incidence2
For both incidence of and mortality from breast cancer, the proportions that occur in women younger than 44 years have been shown to be higher in Latin American countries than in high-income countries (20% vs 12% of new cases and 14% vs 7% of deaths), suggesting an important contribution of genetic and non-genetic risk factors in Latin America. (who.int)
This is despite the fact that the incidence of breast cancer in China was approximately 215,600 patients in 2011, which compares closely to the incidence in the United States of America. (wikipedia.org)
Ovarian7
Dr Sandra Perdomo, a scientist in the Genetic Epidemiology Group at the International Agency for Research on Cancer (IARC), answers questions about the Latin American Consortium for Hereditary Breast Cancer and Ovarian Cancer (LACAM) research project. (who.int)
We hypothesize that additional germline alterations in cancer-related genes that have not yet been described could contribute to the development of hereditary breast cancer and ovarian cancer in admixed populations. (who.int)
Therefore, Latin America is a representative scenario in which to study hereditary breast cancer and ovarian cancer genomics, both because of the presence of admixed ethnicity and because it is a region that is currently undergoing epidemiological transition. (who.int)
The Latin American Consortium for Hereditary Breast Cancer and Ovarian Cancer (LACAM) is a joint regional effort that is aimed at analysing the genetic component and modifying risk factors of inherited breast cancer in individuals in Latin America. (who.int)
This will make it the largest study of hereditary breast cancer and ovarian cancer in these populations. (who.int)
We want to characterize alterations in additional cancer-related genes that have not previously been associated with hereditary breast cancer and ovarian cancer in Latin America and to identify non-genetic modifying risk factors that could potentially be relevant for preventive interventions. (who.int)
An additional aim is to develop knowledge translation tools for patients with hereditary breast cancer and ovarian cancer and for clinicians, to support effective communication and sharing of information. (who.int)
Mortality2
In this region, breast cancer is the most common malignancy and the leading cause of cancer-related mortality among women. (who.int)
Additionally, Wisconsin has the nation's third largest Black-White disparity in female breast cancer mortality (rate ratio = 1.600) (6,9). (cdc.gov)
BRCA1
The overexpression in half of the DNA helicase genes was found to be highly correlated with a high HRD score both in BRCA-mutated and BRCA wild-type breast cancer. (hindawi.com)
Molecular1
Thus, it is important to characterize the molecular features of breast cancer with BRCAness phenotype in order to understand the detailed mechanism and to develop a more convenient biomarker for the evaluation of HRD. (hindawi.com)
Findings1
Join us in January as we review the most important findings from the 2019 San Antonio Breast Cancer Symposium. (ahn.org)
Tissue1
Currently, we have recruited 1100 individuals with complete clinical and epidemiological information, including tissue and blood samples. (who.int)
Genes4
In our study, the correlation between the expression of DNA helicase genes and HRD score in breast cancer was analyzed. (hindawi.com)
In conclusion, our study revealed a close relation between the overexpression of certain DNA helicase genes and the deficiency of homologous recombination repair in breast cancer. (hindawi.com)
Moreover, the loss of function in DNA helicase genes including RECQL , BLM , WRN , RECQL5 , and BRIP1 are also known to be highly correlated with the carcinogenesis of breast cancer and the BRCAness phenotype in breast cancer [ 4 - 8 ]. (hindawi.com)
In this study, we comprehensively analyzed the correlation between the expression of DNA helicase genes participated in HR and the HR status in breast cancer defined by the HRD score using TCGA data. (hindawi.com)
Biological1
During a 4-year period, the LACAM research team aims to recruit 3000 cases from multiple centres in six countries in Latin America, collecting biological samples and responses to epidemiological questionnaires and clinical questionnaires. (who.int)
Study2
For instance, a 2019 study found that reflexology was beneficial for individuals with breast cancer. (medicalnewstoday.com)
1956). The anatomical approach to the study breast cancer in young adult women. (who.int)
Therapy1
Breast Cancer - as part of CMF (cyclophosphamide-methotrexate-fluorouracil) therapy. (pfizermedicalinformation.ca)
Individuals1
The clinical pharmacology of methotrexate has not been well studied in older individuals. (pfizermedicalinformation.ca)