BRCA2 ProteinBRCA1 ProteinGenes, BRCA1Genetic Predisposition to DiseaseBreast NeoplasmsCell CycleGenes, BRCA2Cell Cycle ProteinsDNA DamageMutationCheckpoint Kinase 2Germ-Line MutationDNA RepairGenes, cdcNeoplasm ProteinsGenetic TestingDNA-Binding ProteinsNuclear ProteinsProtein-Serine-Threonine KinasesCase-Control StudiesAllelesGenotypeG2 PhaseTumor Suppressor ProteinsPolymorphism, Single NucleotideHeterozygoteBreastCell Line, TumorBreast Neoplasms, MaleOvarian NeoplasmsPedigreeCell Cycle CheckpointsGene Expression Regulation, NeoplasticMitosisDisease SusceptibilityTranscription FactorsDNA Mutational AnalysisAtaxia Telangiectasia Mutated ProteinsRad51 RecombinaseMolecular Sequence DataMutation, MissenseNeoplastic Syndromes, HereditaryPolymorphism, GeneticS PhaseGenetic LinkageRisk FactorsProtein KinasesTumor Suppressor Protein p53Tumor Cells, CulturedPoint MutationBase SequenceG2 Phase Cell Cycle CheckpointsHydroxyureaSpindle ApparatusFamily HealthPhenotypePolymerase Chain ReactionReceptors, EstrogenM Phase Cell Cycle CheckpointsChromosome MappingG1 PhaseDNA ReplicationSignal TransductionGamma RaysHaplotypesGenome-Wide Association StudyExonsDNA, NeoplasmPhosphorylationAmino Acid SequenceSaccharomyces cerevisiae ProteinsReceptors, ProgesteroneApoptosisGene FrequencyProstatic NeoplasmsGenetic MarkersGenes, p53Genetic VariationAtaxia TelangiectasiaRNA, MessengerGenetic LociMad2 ProteinsFungal ProteinsCell DivisionSchizosaccharomycesSaccharomyces cerevisiaeGenes, Tumor SuppressorCarcinoma, Ductal, BreastSchizosaccharomyces pombe ProteinsChromosomes, Human, Pair 6Radiation, IonizingCell LineUltraviolet RaysChromosomal InstabilityPrognosisCyclinsCyclin-Dependent Kinase Inhibitor p21NeoplasmsGenomic InstabilityGene Deletion