BRCA2 ProteinBRCA1 ProteinGenes, BRCA1Cell CycleGenetic Predisposition to DiseaseBreast NeoplasmsCell Cycle ProteinsGenes, BRCA2DNA DamageCell DivisionCheckpoint Kinase 2MutationGenes, cdcDNA RepairMitosisNeoplasm ProteinsProtein-Serine-Threonine KinasesDNA-Binding ProteinsG2 PhaseGerm-Line MutationNuclear ProteinsGenetic TestingTumor Suppressor ProteinsAllelesCase-Control StudiesCell Line, TumorGenotypePolymorphism, Single NucleotideBreastCell Cycle CheckpointsBreast Neoplasms, MaleOvarian NeoplasmsMolecular Sequence DataTranscription FactorsS PhaseGene Expression Regulation, NeoplasticDisease SusceptibilityAtaxia Telangiectasia Mutated ProteinsHeterozygoteRad51 RecombinaseProtein KinasesDNA ReplicationPedigreeNeoplastic Syndromes, HereditarySpindle Apparatuscdc25 PhosphatasesG1 PhasePolymorphism, GeneticDNA Mutational AnalysisTumor Cells, CulturedRisk FactorsHydroxyureaGenetic LinkageSchizosaccharomycesSaccharomyces cerevisiaeTumor Suppressor Protein p53CDC2 Protein KinaseBase SequenceG2 Phase Cell Cycle CheckpointsSaccharomyces cerevisiae ProteinsFungal ProteinsPhosphorylationPhenotypeSignal TransductionCyclinsM Phase Cell Cycle CheckpointsSchizosaccharomyces pombe ProteinsAmino Acid SequenceReceptors, EstrogenApoptosisGamma RaysChromosome MappingFamily HealthGenes, FungalRNA, MessengerModels, BiologicalHaplotypesGenome-Wide Association StudyCyclin BHeLa CellsCell ProliferationReceptors, ProgesteroneCell LineMad2 ProteinsProstatic NeoplasmsAtaxia TelangiectasiaRetinoblastoma ProteinGenetic LociCell NucleusDNACarcinoma, Ductal, BreastPolymerase Chain ReactionGenetic MarkersTime FactorsRadiation, IonizingCyclin-Dependent KinasesRNA, Small InterferingCyclin B1Chromosomal InstabilityGenetic Variation