Breast cancer survival. Medical search. Frequent questions

A new clinical trial has shown that reducing the interval between successive doses of a commonly used chemotherapy regimen improves survival in women whose breast cancer has spread to the lymph nodes. (scienceblog.com)
While previous research has evaluated the use of various forms of "dose dense" chemotherapy, this is the first major controlled study to show a clear survival benefit for women with node-positive breast cancer. (scienceblog.com)
This study suggests that many women with breast cancer may benefit from chemotherapy administered on a condensed schedule," said Marc L. Citron, M.D., Albert Einstein College of Medicine, who is the lead investigator of the study. (scienceblog.com)
With the availability of new drugs to control one of the most serious side effects of chemotherapy administration, we can further increase the chances of survival for women with breast cancer. (scienceblog.com)
Researchers tested both dose dense and conventional chemotherapy regimens in 1,973 women with node-positive primary breast cancer and no other metastases. (scienceblog.com)
It is too soon to determine whether a dose dense chemotherapy regimen with filgrastim should be the new standard of care," said Jeffrey Abrams, the oncologist in charge of breast cancer treatment trials at NCI. (scienceblog.com)
In addition to improved disease-free survival, the study indicated that dose dense chemotherapy may also lead to higher overall survival rates. (scienceblog.com)
She informed me I would need an aggressive type of chemotherapy because of my age and type of cancer. (youngsurvival.org)
Treatment [vic]-trastuzumab duocarmazine improved progression-free survival for patients with pretreated, metastatic HER2-positive breast cancer when compared with physician's choice chemotherapy. (cancernetwork.com)
Eligible participants were women diagnosed between 2010 and 2018 with ER-positive, pT1-3N0-1aM0 breast cancer who underwent surgery and received adjuvant endocrine therapy with or without chemotherapy. (medpagetoday.com)
The trial evaluated margetuximab compared with trastuzumab, in combination with chemotherapy, for the treatment of HER 2-positive breast cancer. (pharmacytimes.com)
Margetuximab, an investigational monoclonal antibody, improved progression-free survival (PFS) when used in combination with chemotherapy in patients with human epidermal growth factor receptor 2- (HER2) positive metastatic breast cancer, according to new data from a pivotal phase 3 trial. (pharmacytimes.com)
The SOPHIA study, which enrolled 536 patients, evaluated margetuximab in combination with chemotherapy compared with trastuzumab (Herceptin) plus chemotherapy in treating patients with HER2-positive breast cancer. (pharmacytimes.com)
His team followed 2,300 early-stage breast cancer patients who had been treated with chemotherapy. (drmirkin.com)
Doctors usually treat triple-negative breast cancers with surgery, chemotherapy , and in many cases, radiation therapy . (hdkino.org)
The use of trastuzumab, chemotherapy and surgery among women with HER2-positive metastatic breast cancer significantly improved survival from the time central nervous system metastases were diagnosed. (medicalxpress.com)
Based on these study results, lead researcher Adam Brufsky, M.D., Ph.D., said, "We clearly now know that these women should get trastuzumab and potentially chemotherapy, even if cancer spreads to the brain. (medicalxpress.com)
It is surprising that chemotherapy/trastuzumab adds to these women's survival," Brufsky said. (medicalxpress.com)
Individuals had HER2-positive metastatic breast cancer and had previously received trastuzumab and taxanes, with up to two prior lines of chemotherapy for metastatic disease. (physiciansweekly.com)
In most protocol-prespecified subgroups, including patients without prior trastuzumab resistance, those with prior trastuzumab resistance, and patients without previous chemotherapy in the metastatic setting, the overall survival benefits of pyrotinib plus capecitabine over lapatinib plus capecitabine were observed. (physiciansweekly.com)
Prof Christopher Twelves, speaking at the 2010 ASCO conference: A Phase III randomised trial finds that a new chemotherapy agent, eribulin mesylate, extends median overall survival by 2.5 months among women with locally recurrent or metastatic breast cancer who had already been heavily treated with conventional therapies. (ecancer.org)
The trial supported the December 2020 approval of margetuximab for use in combination with chemotherapy for adults with metastatic HER2-positive breast cancer who have received two or more prior anti-HER2 regimens, at least one of which was for metastatic disease. (ascopost.com)
Margetuximab plus chemotherapy improved progression-free survival vs trastuzumab plus chemotherapy in patients with pretreated ERBB2-positive advanced breast cancer. (ascopost.com)
Dr. Ravdin, then Chairman of the Clinical Studies Panel of the Cancer Chemotherapy National Service Center at the National Institutes of Health (NIH), asked Dr. Fisher to attend a meeting with 22 other surgeons to discuss the creation of the Surgical Adjuvant Chemotherapy Breast Project, which later became known as the National Surgical Adjuvant Breast and Bowel Project (NSABP), chaired by Dr. Fisher for 30 years. (ascopost.com)
The study found that while the drug provided a significant benefit in recurrence-free survival in premenopausal women, altering the course of their breast cancer, the fact that the chemotherapy did not benefit all patients and caused some side effects made physicians reluctant to embrace the use of systemic adjuvant therapy. (ascopost.com)
Because the cancer cells don't have these proteins, hormone therapy and drugs that target HER2 are not helpful, so chemotherapy (chemo) is the main systemic treatment option . (knowbreastcancer.org)
Treatment options for metastatic breast cancer include systemic therapies (chemotherapy, hormone therapy), surgery, and/or radiation [ 4 ]. (biomedcentral.com)
Endocrine therapy is the preferred treatment for patients with stage III or IV hormone-receptor-positive (HR +, which includes ER and/or PR positive) breast cancer, but chemotherapy may also be recommended for cases with rapidly progressive disease [ 4 , 5 ]. (biomedcentral.com)
Background: No studies have attempted to determine whether nodal surgery utilization, time to initiation and completion of chemotherapy or surveillance mammography impact breast cancer survival. (tmc.edu)
Objectives and Methods: To determine whether receipt of nodal surgery, initiation and completion of chemotherapy, and surveillance mammography impact of racial disparities in survival among breast cancer patients in SEER areas, 1992-2005. (tmc.edu)
Patients who initiated chemotherapy more than three months after surgery were 1.8 times more likely to die of breast cancer (95% CI 1.3-2.5) compared to those who initiated chemotherapy less than a month after surgery, even after controlling for known confounders or controlling for race. (tmc.edu)
Despite correcting for chemotherapy initiation and completion and known predictors of outcome, African American women still had worse disease specific survival than their Caucasian counterparts. (tmc.edu)
Conclusions: The disparities in survival among African American and Hispanic women with breast cancer are not explained by nodal surgery utilization or chemotherapy initiation and chemotherapy completion. (tmc.edu)
Nomogram for predicting survival in patients with mucinous breast cancer undergoing chemotherapy and surgery: a population-based study. (bvsalud.org)
Used in the frontline setting, zolbetuximab (under development by Ganymed Pharmaceuticals AG) combined with chemotherapy led to significantly longer progression-free survival and overall survival compared to what was seen with chemotherapy alone. (medscape.com)
An increasing number of patients are receiving neoadjuvant treatment, e g chemotherapy before cancer surgery in contrast to treatment after surgery. (lu.se)

The randomized, Phase II PALOMA-1 trial was designed to assess whether palbociclib plus letrozole compared to just letrozole significantly improved progression-free survival in ER-positive, HER2-negative patients with locally advanced or metastatic breast cancer. (genomeweb.com)
LBA15 - Primary outcome of the phase III SYD985.002/TULIP trial comparing [vic-]trastuzumab duocarmazine to physician's choice treatment in patients with pre-treated HER-positive locally advanced or metastatic breast cancer. (cancernetwork.com)
Despite differences in tumors, the addition of CDK 4/6 inhibitors to endocrine therapy showed a benefit in patients with hormone receptor-positive, HER2-negative, advanced or metastatic breast cancer compared with endocrine therapy alone. (curetoday.com)
Adding CDK 4/6 inhibitors to endocrine therapy for patients with hormone receptor-positive, HER2-negative, advanced or metastatic breast cancer showed a survival benefit despite patients having differences in their tumors, according to a study published in Lancet Oncology. (curetoday.com)
In this subgroup analysis, Kisqali plus endocrine therapy increased OS compared to endocrine therapy alone among women with hormone receptor positive, human epidermal growth factor receptor-2 negative (HR+/HER2-) advanced or metastatic breast cancer with visceral metastases, consistent with the benefit seen in the overall study populations. (epicos.com)

Guidelines of the European Society of Medical Oncology (ESMO), the European Reference Network for Paediatric Cancers (PaedCan), and the European Network for Rare Adult Solid Cancer (EURACAN) recommend radiography for the initial evaluation of osteosarcoma. (medscape.com)
Joint guidelines from the European Society for Medical Oncology, European Reference Network for Paediatric Cancers, and European network for Rare adult solid Cancer (ESMO-PaedCan-EURACAN) recommend conventional radiography in two planes as the first radiological investigation. (medscape.com)

July 19, 2023 Women diagnosed and treated for breast cancer have increased biological aging compared to women who remain free of breast cancer, according to a new study. (sciencedaily.com)
THURSDAY, Nov. 16, 2023 (HealthDay News) - For patients with human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer, pyrotinib plus capecitabine offers an overall survival benefit, according to a study presented at the Advanced Breast Cancer Seventh International Consensus Conference, held from Nov. 9 to 11 in Lisbon, Portugal. (physiciansweekly.com)
The findings were presented here at the Gastrointestinal Cancers Symposium (GICS) 2023, organized by the American Society of Clinical Oncology. (medscape.com)

This difference corresponded to a 26 percent overall reduction in the risk of cancer recurrence. (scienceblog.com)
However, the reduced risk of cancer recurrence and the low occurrence of side effects are encouraging, and further follow-up as well as other studies testing this approach will hopefully confirm the findings. (scienceblog.com)
3 It is unclear, however, whether a similar linkage exists between low income and 21-gene recurrence score (RS) in estrogen receptor (ER)-positive breast cancer, which is much more common. (medpagetoday.com)
A deficiency of any vitamin can weaken your immunity and increase risk for cancer recurrence. (drmirkin.com)
Regular survivorship exercise will decrease breast cancer recurrence. (nujournal.com)
Although researchers have been able to estimate the number of women initially diagnosed with MBC, data on the number of women whose cancers spread to a distant organ site, either as a progression or recurrence after being first diagnosed with an earlier stage of breast cancer, has been lacking because U.S. registries do not routinely collect or report data on recurrence. (managedhealthcareexecutive.com)
Collecting recurrence data has been challenging for cancer registries because recurrence can be diagnosed through diverse methods and in a variety of locations. (managedhealthcareexecutive.com)
Breast carcinoma: pattern of recurrence and metastasis after mastectomy. (aaem.pl)
Insa A, LLuch A, Prosper F, Marguan I, Marginez-Agullo A, Garcia-Conde J. Prognostic factors predicting survival from first recurrence in patients with metastatic breast cancer: analysis of 439 patients. (aaem.pl)
What type breast cancer has the highest recurrence rate? (knowbreastcancer.org)
In this study, the researchers looked at the risk of late breast cancer recurrence, meaning the breast cancer came back 10 or more years after diagnosis. (knowbreastcancer.org)
Qiu S, Jiang C. Soy and isoflavones consumption and breast cancer survival and recurrence: a systematic review and meta-analysis. (medlineplus.gov)

Published in the October 15, 2006 issue of CANCER, a peer-reviewed journal of the American Cancer Society, the study found that obese and overweight women who had higher levels of moderate or vigorous recreational physical activity within one year before diagnosis tended to have better five-year survival patterns compared to other groups. (sciencedaily.com)
While exercise has been shown to be a significant factor in preventing breast cancer, its role in prognosis after diagnosis remains unclear but has also been infrequently studied. (sciencedaily.com)
Page E. Abrahamson, Ph.D. now at the Fred Hutchinson Cancer Research Center in Seattle, led researchers while at the University of North Carolina, Chapel Hill to investigate the relationship between pre-diagnosis physical activity and survival in 1264 women with breast cancer. (sciencedaily.com)
Survival modestly increased among women with body mass index (BMI) greater than 25 who reported highest levels of physical activity within one year of diagnosis. (sciencedaily.com)
Recently, specialists from Queen Mary University of London in the United Kingdom, the Falun Central Hospital in Sweden, and numerous other research institutions worldwide set out to establish just how important breast screening is in increasing survival rates following diagnosis. (medicalnewstoday.com)
To improve the assessment of how organized breast screening initiatives would impact health outcomes, the experts who conducted the recent study used a new method that involved calculating the annual incidence of breast cancers leading to death within 10 years and within 20 years following diagnosis. (medicalnewstoday.com)
The investigators found that the women who had joined an organized breast cancer screening program had a 60 percent lower risk of death within 10 years following breast cancer diagnosis. (medicalnewstoday.com)
They also had a 47 percent lower risk of death within 20 years after breast cancer diagnosis. (medicalnewstoday.com)
Higher levels of physical activity have been associated with improved survival after breast cancer diagnosis. (nih.gov)
Relative survival after breast cancer diagnosis males by ethnicity U.S. (statista.com)
The relative survival rate for U.S. males diagnosed with breast cancer was lowest amongst black, non-Hispanic individuals compared to those of other race/ethnicities, at both 1 year and 5 years after diagnosis. (statista.com)
This statistic shows the relative survival 1 and 5 years after breast cancer diagnosis among U.S. males from 2007 to 2016, by race/ethnicity. (statista.com)
Older women with breast cancer have poorer relative survival outcomes, but whether achieving earlier stage at diagnosis would translate to substantial reductions in mortality is uncertain. (nature.com)
For a typically sized annual cohort in the East of England, 27 deaths in women with breast cancer aged 75+ years can be postponed within 5 years from diagnosis if their stage distribution matched that of the women aged 70-74 years (4.8% of all 566 deaths within 5 years post diagnosis in this population). (nature.com)
Against this background, we have set out to examine the potential for preventing deaths within 5 years from diagnosis of breast cancer in older women that could result from eliminating age inequalities in stage at diagnosis. (nature.com)
We analysed time from diagnosis to death for East of England women aged 70 years or over with a new diagnosis of breast cancer (International Classification of Diseases-10 site code C50) during 2006-2010, with follow-up on mortality until 15 March 2012. (nature.com)
Their statistical analysis included data on 4,443 breast cancer patients who had their blood levels tested at the time of diagnosis, as well as at follow-up intervals that occurred periodically for about nine years thereafter. (naturalnews.com)
The group of patients object of study showed an elevated global survival, which was mainly associated to older ages, the early diagnosis of the disease and the performance of radical surgery. (medigraphic.com)
All-cause mortality is decreased in women undergoing annual mammography before breast cancer diagnosis. (medigraphic.com)
Triple-negative cancers have a more aggressive course than other breast cancers and are more likely to recur over the first few years after diagnosis. (hdkino.org)
While most breast lumps are harmless (benign), every breast lump should be evaluated by a doctor to exclude or establish a diagnosis of cancer. (hdkino.org)
In addition, for those patients without central nervous system metastases at initial diagnosis, cancer progressed to the brain about 13 months after diagnosis. (medicalxpress.com)
Looking at breast cancer survival on a population level can tell us how effective our public health and health care systems are at early diagnosis, delivery of evidence-based treatment, and management of follow-up care. (cdc.gov)
American Indian/Alaska Native women are more often diagnosed at younger ages and have worse survival after diagnosis. (cdc.gov)
Soon after breast cancer diagnosis, it is important that each patient understands her disease and treatment plan. (cdc.gov)
From 2004 to 2009, about 89% of white women and about 78% of black women survived at least five years after a breast cancer diagnosis. (cdc.gov)
Researchers came to this finding by estimating the number of U.S. women living with MBC, or breast cancer that has spread to distant sites in the body, including women who were initially diagnosed with metastatic disease, and those who developed MBC after an initial diagnosis at an earlier stage. (managedhealthcareexecutive.com)
Instead, Dr. Fisher proposed, breast cancer is a systemic disease in which malignant cells are likely disseminated throughout the body before diagnosis, and radical mastectomies are unlikely to improve overall survival. (ascopost.com)
While a diagnosis of triple-negative breast cancer can be terrifying, it is not a death sentence , Torrey says. (knowbreastcancer.org)
Research suggests that estrogen receptor-positive breast cancer is more likely to come back more than five years after diagnosis. (knowbreastcancer.org)
Within 4 months of cancer diagnosis, surgery and radiation were received by 39% and 32% of study patients, respectively. (biomedcentral.com)
This study aimed to identify and describe all published observational studies reporting NPI-category-specific overall survival following a diagnosis of early and/or locally advanced breast cancer. (biomedcentral.com)
During her journey, she authored The Big Discovery, a children's book that guides families through a breast cancer diagnosis. (cdc.gov)
Survival is lower in black women than in white women at all stages of diagnosis (1). (cdc.gov)
With advances in detection and treatment, the population of breast cancer survivors is expected to increase by 25% to almost 4 million by the year 2024, and approximately nine out of every ten breast cancer patients are expected to live at least five years after diagnosis. (cdc.gov)
Screening for depressed mood at diagnosis and providing treatment might be an effective strategy to improve continued workforce participation in African American breast cancer patients. (cdc.gov)

Black women have a 36% higher breast cancer mortality rate than other races in spite of having a similar incidence to White women. (sciencedaily.com)
Despite improvements in treatment options and survival outcomes in recent years, NZ ABC mortality rates continue to exceed the OECD average [ 1 ]. (hindawi.com)
Bowel cancer is the fourth most common cancer in the UK, with the second highest mortality rate. (wcrf-uk.org)
And, for women in rural areas, the decrease in breast cancer mortality has been slower. (cdc.gov)
Banas T, Juszczyk G, Pitynski K, Nieweglowska D, Ludwin A, Czerw A. Incidence and mortality rates in breast, corpus uteri, and ovarian cancers in Poland (1980-2013): an analysis of population-based data in relation to socioeconomic changes. (aaem.pl)
We found that non-whites underwent surveillance mammography less frequently compared with whites and mammography use during a one- or two-year time interval was associated with a small reduced risk of breast-cancer-specific and all-cause mortality. (tmc.edu)
We found that while adjustment for surveillance mammography receipt and physician visits reduced differences in mortality between blacks and whites, these survival disparities were eliminated after adjusting for the number of surveillance mammograms received. (tmc.edu)
Surveillance mammograms, physician visits and number of mammograms received may play a major role in achieving equal outcomes for breast cancer-specific mortality for women diagnosed with primary breast cancer. (tmc.edu)
In this large population-based cohort of patients with registry-confirmed breast cancer, we found increased breast cancer mortality among SSRI users. (medscape.com)
Breast cancer incidence and mortality in the United States and worldwide have increased in cohorts of women born since 1900, for reasons not well understood (3,4). (cdc.gov)
Age-adjusted rates of breast cancer mortality were 12% higher in black women than in white women (5). (cdc.gov)
When age-adjusted to the 1986 U.S. population, breast cancer mortality rates in 1986 were generally lower in southern states and higher in northern states (Table 1, Figure 1). (cdc.gov)
To assess the efficacy of combined mammography and physical breast examination in reducing breast cancer mortality, a large randomized clinical trial was conducted at the Health Insurance Plan in New York City in the mid-1960s (14). (cdc.gov)
Nonuse increases with age and is thus inversely associated with risk of breast cancer mortality. (cdc.gov)
With this approach, we aim to bolster the role of primary health care services to help avert excess mortality of African women from preventable cancers," said Dr Matshidiso Moeti, WHO Regional Director for Africa. (who.int)
Early detection of breast cancer is important to reduce morbidity and mortality. (lu.se)
Nevertheless, in contrast to recent incidence rates, racial disparities in breast cancer survival persist, with five-year survival rates of 81% for African-American women and 92% for white women, and long-term mortality rates that are 42% higher in African-American women than white women. (cdc.gov)

But multiple factors can influence oncologists' choice of which drug to use for which patients, said Melissa McShane, M.D., of the Breast Cancer Oncology Program at Fox Chase Cancer Center. (cancer.gov)
vic]-trastuzumab duocarmazine) can provide a new treatment option for patients with pretreated, locally advanced or metastatic HER2-positive breast cancer," said study author Cristina Saura Manich, MD, PhD, head of the Breast Cancer Unit of the Service of Medical Oncology at Vall d'Hebron University Hospital in Barcelona, Spain, while presenting the findings. (cancernetwork.com)
We have known that income level is associated with incidence of poor-prognosis triple-negative breast cancer, but our new study presents the first data to show that income level impacts survival even in breast cancer with a better prognosis," says co-author Anurag K. Singh, MD, Professor of Oncology at Roswell Park Comprehensive Cancer Center. (medpagetoday.com)
Led by researchers from Roswell Park Comprehensive Cancer Center, the study used data from the National Cancer Database, a nationwide clinical oncology database sponsored jointly by the American Cancer Society and the American College of Surgeons Commission on Cancer. (medpagetoday.com)
There are currently no approved agents for the treatment of patients with metastatic HER2+ breast cancer who have previously received trastuzumab, pertuzumab, and ado-trastuzumab emtansine," Hope S. Rugo, MD, director of Breast Oncology and Clinical Trials Education at the University of California San Francisco Comprehensive Cancer Center, said in a press release. (pharmacytimes.com)
Those who had 10+ pounds of excess body fat had a 35 percent increased risk of breast cancer, and those who had "normal body weight" but had excess fat in their bellies had a 56 percent increased risk for developing estrogen-dependent breast cancer ( JAMA Oncology , December 6, 2018). (drmirkin.com)
Furthermore, the current American Society of Clinical Oncology endocrine therapy guidelines for treating patients with metastatic breast cancer call for CDK inhibitor-based therapy in the first- and second-line settings. (curetoday.com)
The theme of the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting is Advancing Equitable Cancer Care Through Innovation . (cancer.net)
Oncology nurses are in a particularly good position to educate, navigate, and advocate for cancer patients. (cdc.gov)
Superior overall survival with Kisqali is proven in two phase III trials, and this subgroup analysis shows that Kisqali could make a difference in survival even among patients with the most aggressive forms of advanced breast cancer," said Susanne Schaffert, PhD, President, Novartis Oncology. (epicos.com)
Dr. Cristina M. Checka is an assistant professor in the Department of Breast Surgical Oncology, Division of Surgery at the University of Texas MD Anderson Cancer Center. (cdc.gov)
Dr. Checka earned her medical degree from Michigan State University, completed her residency in general surgery at Eastern Virginia Medical School, and her breast surgical oncology fellowship in 2008 at New York University. (cdc.gov)
Ashley is a research advocate with Houston Methodist Research Institute and a member of the National Cancer Institute, National Institute of Health Physical Sciences-Oncology Advocacy Network, and the Penn Medicine: Basser Center for BRCA Young Leadership Council. (cdc.gov)
Zolbetuximab plus mFOLFOX6 is a new potential standard treatment for these patients," said lead study author Kohei Shitara, MD, Department of Gastrointestinal Oncology, National Cancer Center Hospital East Kashiwa City, Chiba, Japan. (medscape.com)

However, this is still the most invasive cancer among females. (medicalnewstoday.com)
At the age of 29, I was diagnosed with Stage 1 ductal invasive breast cancer. (youngsurvival.org)
The new study included more than 2,200 women who were diagnosed with early-stage, invasive breast cancer between 1997 and 2000. (healthday.com)
In the U.S., almost 200,000 women will be diagnosed with invasive or in situ breast cancer each year. (green-tea-health-news.com)
In 2019, about 2,670 new cases of invasive breast cancer will be diagnosed in men. (technologynetworks.com)
Breast cancer is the most common invasive cancer in women and the second leading cause of death from cancer among women in the United States (US) [ 1 ]. (biomedcentral.com)
Despite more than 15 years of experience as a nurse, her most valuable resource has been as a patient, having been diagnosed with invasive breast cancer in 2012 at age 32. (cdc.gov)

The researchers found that two dose dense regimens provided significantly higher disease-free survival rates than two regimens using conventional dosing, and that efficacy did not differ between the two dose dense regimens. (scienceblog.com)
Their results indicate that breast cancer treatments significantly reduce cardiopulmonary function-a problem that can persist for years after treatment ends. (alive.com)
All breast cancer patients, regardless of treatment stage, had significantly worse cardiopulmonary function than inactive healthy women of the same age. (alive.com)
The findings of this investigation from Roswell Park Comprehensive Cancer Center showed that more aggressive tumor biology and significantly shorter survival were linked with low household income, even in breast cancer with a better prognosis. (medpagetoday.com)
High levels of this prohormone, it turns out, more than double a woman's chances of surviving breast cancer, while low levels significantly increase her risk of death. (naturalnews.com)
Studies show strength training and mind/body exercises such as yoga and meditation significantly improve symptoms associated with breast cancer treatment. (nujournal.com)
However, Cox proportional regression showed that tumour stage was the only factor that significantly influenced survival analysis after controlling for other factors. (who.int)
Median overall survival was significantly longer for patients who received zolbetuximab in comparison with those who did not (13.2 vs 8.4 months). (medscape.com)

The study included pooled individual patient data from all phase 3 randomized breast cancer trials of CDK inhibitors plus endocrine therapy submitted to the FDA before Jan 1, 2019. (curetoday.com)
At the second planned interim analysis of overall survival in Septem ber 2019, the median follow-up for overall survival was 15.6 months. (ascopost.com)
A 2019 British Medical Journal analysis determined that only about 2% of official bilateral and multilateral development aid is targeted at noncommunicable diseases, including breast and cervical cancer, The African region accounts for only 1% of world health expenditure, despite having 24% of the global disease burden, according to a 2019 report by the University of Washington's Institute for Health Metrics and Evaluation. (who.int)

The researchers believe that screening allows specialists to detect cancer tumors at an early stage, which means the tumors can be treated sooner, and they will respond better to therapy. (medicalnewstoday.com)
High expression of LMNB2 in CRC tumors correlates with worse disease-free cumulative and overall survival, and that knocking out the LMNB2 gene allowed for the development of CRC tumors through a mechanism that involved silencing of p21 expression. (news-medical.net)
BRCA1 mutations also predict worse overall survival compared to patients harboring wild-type BRCA1 tumors. (news-medical.net)
Margetuximab is designed to target the HER2 oncoprotein, which is expressed by tumor cells in breast, gastroesophageal, and other solid tumors. (pharmacytimes.com)
The highest average survival was found in patients aged between 71-80 and over 80 years who had a lobular carcinoma, who had tumors in clinical stage IIa and who were subject to radical mastectomies. (medigraphic.com)
Although Dr. Fisher was initially hesitant to change the focus of his research from liver regeneration and transplantation to breast cancer and the study of malignant disease, he was intrigued by the question of how tumors metastasize. (ascopost.com)
But the green tea extract group had delayed onset, smaller tumors, and triple the breast cancer survival rate. (green-tea-health-news.com)
Breast cancers are most often epithelial tumors involving the ducts or lobules. (msdmanuals.com)
General references Breast cancers are most often epithelial tumors involving the ducts or lobules. (msdmanuals.com)

1,2 In particular, low SES and income levels are known to be associated with a higher incidence of triple-negative breast cancer. (medpagetoday.com)
We have known that income level is associated with incidence of poor-prognosis triple-negative breast cancer, but our new study presents the first data to show that income level impacts survival even in breast cancer with a better prognosis. (medpagetoday.com)
The incidence and 10-year survival of interval breast cancers in Wales. (medigraphic.com)
Brufsky and colleagues used data from the registHER study to evaluate the incidence, potential risk factors and outcomes for patients with HER2-positive breast cancer. (medicalxpress.com)
The prognosis of patients with mucinous breast cancer (MuBC) is affected by several factors, but the low incidence of MuBC makes it difficult to conduct extensive and in-depth studies. (bvsalud.org)

They evaluated how patients with HER2-positive breast cancer develop brain metastases , and followed them to examine what happens thereafter. (medicalxpress.com)

Researchers have discovered that cardio fitness levels may be important indicators of breast cancer survival. (alive.com)
Researchers at Duke University Medical Center are among the first to apply these tests to breast cancer patients to see what kind of effect cancer treatments may have on the heart, lungs, and body during exercise. (alive.com)
Researchers speculate that poor cardiopulmonary function may be a strong indicator of survival for women with advanced breast cancer. (alive.com)
Women with breast cancer who follow a low-fat diet are 22% more likely to survive at least 10 years, when compared to women who consume a more normal higher fat diet, according to researchers from Fred Hutchinson Cancer Center in Seattle. (canceractive.com)
THURSDAY, Nov. 15, 2012 (HealthDay News) -- The quality of a breast cancer patient's personal relationships may be as important as the size of her social networks in predicting survival, researchers report. (healthday.com)
Women who were socially isolated were 34 percent more likely to die from breast cancer or other causes than women who were socially integrated, the Kaiser Permanente researchers found. (healthday.com)
NaturalNews) Researchers from the University of California, San Diego (UCSD), have made a fascinating new discovery with regard to vitamin D and the role that it plays in breast cancer survival. (naturalnews.com)
To our knowledge, this is the first comprehensive pooled analysis of all marketed CDKIs (CDK 4/6 inhibitors) to assess efficacy in these less common subgroups of patients with breast cancer," researchers from the Food and Drug Administration (FDA) wrote. (curetoday.com)
Although researchers hypothesized that patients with lobular breast cancer or bone-only metastatic disease would respond well to endocrine therapy alone, and therefore derive a lesser benefit from the addition of CDK inhibitors, they ultimately found that all subgroups of patients benefited from the addition of CDK inhibitors. (curetoday.com)
Across the pooled data, researchers found an estimated difference of 8.8 months in progression-free survival or the time a patient lived without disease worsening, in favor of CDK 4/6 inhibitors over placebo in addition to endocrine therapy, showing a similar treatment effect regardless of the subgroup. (curetoday.com)
From June 3 to 7 in Chicago, Illinois, and online, cancer researchers and clinicians from around the world will gather to discuss the latest research and how to ensure that all people receive the cancer care they need. (cancer.net)
The researchers used data from the National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) Program for this study. (cancer.net)
Using this information, the researchers looked to see if there were connections between 5-year overall survival and social services spending based on race, ethnicity, and type of cancer. (cancer.net)
Ten to 16 percent of women with advanced breast cancer develop central nervous system metastases, the researchers wrote in their study, published in Clinical Cancer Research , a journal of the American Association for Cancer Research. (medicalxpress.com)
Researchers also found that median and five-year relative survival for women initially diagnosed with MBC is improving, especially among younger women. (managedhealthcareexecutive.com)
The researchers estimated that, as of Jan. 1, 2017, more than 150,000 women in this country were living with MBC, and that three out of four of them had initially been diagnosed with an earlier stage of breast cancer. (managedhealthcareexecutive.com)
Researchers estimate a twofold increase in five-year relative survival rate from 18% to 36%, for women initially diagnosed with MBC at age 15 to 49 years between 1992 to 1994 and 2005 to 2012, respectively. (managedhealthcareexecutive.com)
Breast cancer patients with high levels of vitamin D in their blood are twice as likely to survive the disease as women with low levels of this nutrient, report University of California, San Diego School of Medicine researchers in the March issue of Anticancer Research. (grassrootshealth.net)
At Nagoya University Medical School, Japan, researchers initiated breast cancer in rats. (green-tea-health-news.com)
When looking at treatments, the researchers found that men diagnosed with hormone-receptor-positive breast cancer were less likely to be treated with hormonal therapy than women (hormonal therapy is the standard of care for early-stage hormone-receptor-positive breast cancer). (technologynetworks.com)

ABSTRACT The 5-year survival rate of female breast cancer cases in Jordan and some of the factors that affected survival were measured. (who.int)

White, Asian, and Pacific Islander women are more likely to be diagnosed with localized breast cancer than Black, Hispanic, American Indian, and Alaska Native women. (msdmanuals.com)

Identifying factors in cancer patients that predict outcome (i.e., prognosis) is important for physicians planning patient management and patients understanding their disease. (sciencedaily.com)
Adding to the wealth of research on two common forms of cancer, this study shows that exposure to higher body weight in early to mid adulthood plays a major part in cancer prognosis. (wcrf-uk.org)
The study shows that despite the poor prognosis of MBC, survival of women initially diagnosed with MBC has been increasing, especially among women diagnosed at younger ages. (managedhealthcareexecutive.com)
Patients with visceral metastases generally face worse prognosis and a higher risk for treatment resistance, so the consistent overall survival results with Kisqali combination therapy for these patients is compelling. (epicos.com)
Triple-negative breast cancer has a dismal prognosis, especially once it has spread to other organs, due to the lack of effective treatments available at this time. (knowbreastcancer.org)
One reason may be that claudin 18 positivity may be associated with a better prognosis for patients with diffuse gastric cancer, he explained. (medscape.com)
this may be in part because they have a higher rate of triple-negative breast cancer (negative for estrogen and progesterone receptors and human epidermal growth factor receptor [HER2] oncogene), which has a poorer prognosis than other types. (msdmanuals.com)

Young Survival Coalition is a qualified 501(c)(3) tax exempt nonprofit organization dedicated to all young breast cancer survivors and their co-survivor support networks. (youngsurvival.org)
Considering neighborhood factors may aide in the design of more effective, tailored physical activity programs for breast cancer survivors. (nih.gov)
Breast cancer survivors' (BCS) vulnerability to work-related difficulties as part of a constellation of overall psychosocial issues is emerging as an area of concern that should be addressed by practitioners and policymakers. (cdc.gov)
Methods: A systematic review of PubMed, CINAHL, Web of Science, and PsycNET using key terms pertaining to breast cancer, cancer survivors / psychology, and employment was conducted yielding 1,070 citations. (cdc.gov)
Health and employment among working-age cancer survivors. (cdc.gov)

In breast cancer, clinical indicators, such as tumor size, regional lymph node involvement, and estrogen-receptor status, have been shown to influence outcome. (sciencedaily.com)
The only effective way to help prevent arm swelling and arm infections after lymph node surgery for breast cancer is to do continuous arm exercises lasting 10 minutes or more every day. (drmirkin.com)
Stage IV cancers spread beyond the breast and nearby lymph nodes to other parts of the body such as the bones, liver, and lungs. (india4u.com)
His research led him away from the anatomic hypothesis presented by Halsted-that cancer cells, originating from the breast, always passed through the lymph nodes prior to metastatic spread and, therefore, required radical surgery to remove the entire breast, underlying chest muscle, and axillary lymph nodes to halt metastasis. (ascopost.com)
The lymph nodes under your arm are the first place breast cancer is most likely to spread. (knowbreastcancer.org)

Oncotarget published 'Opposing effects of BRCA1 mRNA expression on patient survival in breast and colorectal cancer and variations among African American, Asian, and younger patients' which reported that LMNB2 is a chromatin remodeling protein that also plays a role in eukaryotic cell proliferation by organizing the nuclear membrane during mitosis. (news-medical.net)
2021) Opposing effects of BRCA1 mRNA expression on patient survival in breast and colorectal cancer and variations among African American, Asian, and younger patients. (news-medical.net)

Combined, the studies included 4,443 breast cancer patients. (grassrootshealth.net)

Cancer Australia aims to reduce the impact of cancer, address disparities and improve outcomes for people affected by cancer by leading and coordinating national, evidence-based interventions across the continuum of care. (canceraustralia.gov.au)
Today, research focused on cancer disparities and social determinants of health will be previewed in advance of the meeting. (cancer.net)
There is evidence that spending by states on various social services can mitigate structural racism and partially address social determinants of health, such as financial stability, education, place of residence, and insurance status, but such spending has also been associated with declines in racial and ethnic disparities, leading to unknown overall survival outcomes for patients with cancer. (cancer.net)
Results: Adjusting for nodal surgery did not reduce racial disparities in survival. (tmc.edu)
Understanding how psychosocial health influences returning-to-work outcomes in breast cancer patients could be particularly powerful for developing new strategies to reduce racial disparities in the quality of breast cancer survivorship. (cdc.gov)

Median progression-free survival at that time was 5.8 months (95% confidence interval [CI] = 5.5-7.0 months) in the margetuximab group vs 4.9 months (95% CI = 4.2-5.6 months) in the trastuzumab group (hazard ratio [HR] = 0.76, 95% CI = 0.59-0.98, P = .03). (ascopost.com)
Median overall survival was 21.6 months (95% CI = 18.9-24.1 months) in the margetuximab group vs 19.8 months (95% CI = 17.5-22.3 months) in the trastuzumab group (HR = 0.89, 95% CI = 0.69-1.13, P = .33). (ascopost.com)
In a discussion of the paper, David H. Wang, MD, PhD, an associate professor in the Department of Internal Medicine at University of Texas Southwestern Medical Center, Dallas, pointed out that "zolbetuximab is the first molecularly targeted therapy, exclusive of immune checkpoint inhibitors, to demonstrate a statistically significant survival benefit in first-line treatment of advance gastric cancer since trastuzumab. (medscape.com)

All the women in the trial had already gone through menopause and had cancer that was hormone receptor (HR)-positive and HER2 -negative. (cancer.gov)
Ribociclib is already approved by the Food and Drug Administration as an initial, or first-line, treatment (with an aromatase inhibitor , like letrozole) for postmenopausal women with HR-positive, HER2-negative advanced breast cancer. (cancer.gov)
For many years, treatment of HR-positive, HER2-negative advanced breast cancer was centered around therapies that blunt estrogen's ability to fuel cancer-also called endocrine therapy. (cancer.gov)
Palbociclib, Pfizer's drug for estrogen receptor-positive, HER2-negative locally advanced breast cancer, nearly doubled the time patients lived without tumor progression when administered in combination with the anti-estrogen drug letrozole, compared to letrozole alone, according to the results of the Phase II study PALOMA-1. (genomeweb.com)
PALOMA-1 was split into two parts, wherein the first part included 66 patients with ER-positive, HER2-negative advanced breast cancer and the second part examining 99 patients with ER-positive, HER2-negative disease and specific biomarkers, including cyclin D1 amplification, p16 loss, or both. (genomeweb.com)
Mastectomy to remove the breast containing the original tumour in Stage 4 Her2 +ve breast cancer patients has been shown to increase survival. (canceractive.com)
A mastectomy at any point gives people with stage 4 HER2 breast cancer a greater survival time. (canceractive.com)
Estudio epidemiol gico de la incidencia de la sobreexposici n de HER2 en pacientes portadoras de c ncer de mama de reciente diagn stico en estados iniciales. (medigraphic.com)
Triple-negative breast cancer is an uncommon kind of breast cancer in which the cancer cells test negative for three common markers, the estrogen receptor (ER), progesterone receptor (PR), and a protein involved in cell growth known as HER2. (hdkino.org)
The triple-negative status of a cancer means that anti-hormonal therapies and therapies targeted against the HER2 protein are not effective. (hdkino.org)
Triple-negative breast cancer means the cancer does not express three common markers often found on breast cancer cells: the estrogen receptor (ER), progesterone receptor (PR), and a protein involved in cell growth known as HER2. (hdkino.org)
Women with HER2-positive breast cancer have a reasonable chance of living a long time with their disease, and they should be given aggressive therapy where appropriate," added Brufsky, professor of medicine and associate director of clinical investigation at the University of Pittsburgh Cancer Institute. (medicalxpress.com)
Of the 1,023 women newly diagnosed with HER2-positive metastatic breast cancer , 377 had central nervous system metastases. (medicalxpress.com)
Pyrotinib plus capecitabine consistently shows a benefit to patients with HER2-positive metastatic disease in terms of progression-free and overall survival, irrespective of prior treatments," coauthor Xichun Hu, M.D., Ph.D., from the Fudan University Cancer Hospital in Shanghai, said in a statement. (physiciansweekly.com)
The term triple-negative breast cancer refers to the fact that the cancer cells don't have estrogen or progesterone receptors (ER or PR) and also don't make any or too much of the protein called HER2 . (knowbreastcancer.org)
Triple-negative breast cancer (TNBC) doesn't have estrogen or progesterone receptors and also makes too little or none of the HER2 protein. (knowbreastcancer.org)
This rare type of breast cancer lacks all three of the receptors (estrogen, progesterone and HER2) that are commonly found in the breast cancer cells. (knowbreastcancer.org)
Like breast cancer in women, breast cancer in men can be hormone-receptor-positive or hormone-receptor-negative, as well as HER2-positive or HER2-negative. (technologynetworks.com)
Few studies have evaluated survival, treatment, resource use, and costs among women with stage IV ER + breast cancer (BC) who did not receive HER2 targeted therapy. (biomedcentral.com)
325 women with stage IV ER + BC without HER2 targeted therapy were identified and matched to 325 women without cancer. (biomedcentral.com)
We found significant excess clinical and economic burden among women with stage IV ER + breast cancer who did not receive HER2 targeted therapy. (biomedcentral.com)
The National Comprehensive Cancer Network (NCCN) guidelines recommend all patients newly diagnosed with breast cancer be tested for hormone receptor status via expression of estrogen and/or progesterone receptors (ER/PR) and human epidermal growth factor receptor-2 (HER2) [ 4 ]. (biomedcentral.com)

The American Cancer Society has more about survivorship during and after cancer treatment . (healthday.com)
Dr. Checka's day-to-day work involves breast cancer risk assessment and reduction, survivorship, and the surgical treatment of breast cancer. (cdc.gov)
Inclusion/exclusion criteria were guided by the Mehnert (2013) cancer-work model and a broad definition of the concept of "vulnerability" in cancer survivorship described as "the fear that life's safeguards are no longer effective" (Kleban & Glaser, 2015). (cdc.gov)
Survivorship has become the expectation, not the exception, for women who have been diagnosed with breast cancer. (cdc.gov)

Poorer overall survival was associated with lower neighborhood socioeconomic status (SES) (p(trend) = 0.02), whereas better breast cancer-specific survival was associated with a lack of parks, especially among women in high-SES neighborhoods. (nih.gov)
While treatment uptake and survival outcomes were generally comparable across ethnicity and district health boards, dnMBC survival outcomes were considerably poorer than expected, earmarking this subset of patients with ABC for more in-depth research. (hindawi.com)
Leading cancer prevention and survival charity, World Cancer Research Fund (WCRF) today announces research findings showing that higher body weight measured by body mass index (BMI) in early to mid-adulthood means a poorer survival rate for both breast and colorectal (more commonly known as bowel) cancer patients. (wcrf-uk.org)

In the clinical trial , called MONALEESA-2, women treated with the CDK4/6 inhibitor ribociclib (Kisqali) and the hormone-blocking drug letrozole (Femara) as their initial treatment for advanced breast cancer lived approximately 1 year longer overall than women treated with letrozole alone . (cancer.gov)
This is the longest median survival reported to date in any advanced breast cancer phase 3 clinical trial ," said the study's lead researcher, Gabriel Hortobagyi, M.D., of the University of Texas MD Anderson Cancer Center. (cancer.gov)
Two other CDK4/6 inhibitors- palbociclib (Ibrance) and abemaciclib (Verzenio) -are also approved for the treatment of people with this same form of breast cancer, both based on large clinical trials in which the drugs were shown to improve progression-free survival. (cancer.gov)
Besides the socio-demographic variables, it was analyzed: Affected breast, Tumor location, Histological type, Clinical state at the moment of the operation and surgical technique used. (medigraphic.com)
However, new study findings, presented at the virtual American College of Surgeons (ACS) Clinical Congress 2021, showed that surgery does have survival benefits for men with stage IV breast cancer, she said. (india4u.com)
Garland recommended randomized controlled clinical trials to confirm the findings but suggested physicians consider adding vitamin D into a breast cancer patient's standard care now and then closely monitor the patient. (grassrootshealth.net)
His laboratory and clinical investigations led to more effective therapy, increased survival rates, and improved quality of life for women with breast cancer. (ascopost.com)
The meeting at the NIH resulted in the 1958 launch of the first randomized clinical trial to evaluate the use of systemic therapy following radical mastectomy in the treatment of breast cancer. (ascopost.com)
The substantial differences between studies in the relationship between NPI categories and survival at 5 and 10 years poses challenges for use of this prognostic score in both clinical settings and in decision-analytic model-based economic evaluations. (biomedcentral.com)
Her clinical interests include management of women with an increased risk of and with breast cancer. (cdc.gov)
In 1986, breast cancer (International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) 174) was the underlying cause of death for 40,534 women in the United States. (cdc.gov)
The two principal modes established for secondary prevention are clinical breast examination and mammography (13). (cdc.gov)

Patients with central nervous system metastases were younger, and more likely to have hormone receptor negative disease and higher disease burden compared with those whose cancer did not spread to the brain. (medicalxpress.com)
Is there a rationale for aggressive breast cancer liver metastases resections in Polish female patients? (aaem.pl)
Resection of Single Metachronous Liver Metastases from Breast Cancer Stage I-II Yeld Excellent Overall and Disease-Free Survival. (aaem.pl)
Predictive Profile-Normogram for Liver Resection for Breast Cancer Metastases: An Aggressive Approach with Promising Results Ann Surg Oncol. (aaem.pl)

This is one of the longest median overall survival outcomes for patients with locally advanced mG/GEJ adenocarcinoma in phase 3 trials, Shitera emphasized. (medscape.com)

survival analysis, breast neoplasms, surgery. (medigraphic.com)
Zielinski J, Jaworski R, Irga-Jaworska N, Haponiuk I, Jaskiewicz J. The significance of ductoscopy of mammary ducts in the diagnostics of breast neoplasms. (aaem.pl)

The composite median overall survival (medOS) of women in NZ with ABC was 16 months, while one-year and five-year survival rates were documented at 46% and 12%, respectively. (hindawi.com)

They added that it's important to follow these results as they mature and to continue assessing other biomarkers that could also indicate whether patients with metastatic breast cancer need CDK inhibitors along with their endocrine therapy. (curetoday.com)

The baseline demographics, disease characteristics and prior treatments related to breast cancer were similar between the treatment groups," Manich said, explaining that the median number of prior treatments was 4 (range, 1-16) in the experimental group and 5 in the physician's choice group. (cancernetwork.com)
Characteristics and results of breast cancer in elderly females treated with curative intent. (medigraphic.com)
More efforts are needed to address the social and economic factors, as well as the comorbidities and biological characteristics of breast cancer that may affect outcomes. (cdc.gov)
The characteristics of the breast cancers and undertreatment of male breast cancer seem to account for much of the difference in survival rates. (technologynetworks.com)

Advanced breast cancer patients with higher levels of cardiopulmonary fitness had higher median survival rates (36 months) compared to women with lower cardio fitness levels (16 months). (alive.com)

long-term cervical cancer survivor. (wikipedia.org)
Brazzaville/New York - An initiative to support better access to breast and cervical cancer detection, treatment and care services is being piloted in three African countries. (who.int)
Breast and cervical cancer currently constitute over half the cancer burden for women in sub-Saharan Africa. (who.int)
In addition, early detection services will be integrated into existing cervical cancer screening clinics to ensure both old and new systems are unified. (who.int)
The aim is to provide an integrated and holistic system of health care that will contribute to addressing the burden of breast and cervical cancer in the African region. (who.int)
Despite being preventable and curable through screening and human papillomavirus (HPV) vaccination, cervical cancer remains the most common cause of all cancer-related deaths in African countries. (who.int)
Together with partners, WHO is supporting countries to scale up screening, early detection treatment and care of breast and cervical cancers among women in sub-Saharan Africa. (who.int)

Women who reported the highest levels of physical activity in the year before they were diagnosed with breast cancer may have higher survival, according to a new study. (sciencedaily.com)
The study paper is now available in Cancer , a journal of the American Cancer Society (ACS). (medicalnewstoday.com)
Recent improvements in treatments have led to reduced deaths from breast cancer," says senior study author Prof. Stephen Duffy, from Queen Mary University of London. (medicalnewstoday.com)
Our results, from precise, individual‐based data covering 6 decades, should provide women and their physicians with reassurance that participating in regular, high‐quality mammography screening is the best way to reduce the risk of a premature death from breast cancer," the study authors conclude in the published paper. (medicalnewstoday.com)
Updated results from a large study have further cemented the role of drugs called CDK4/6 inhibitors in treating people with the most common form of metastatic breast cancer. (cancer.gov)
That is a first for a study involving people with advanced breast cancer, he said. (cancer.gov)
The improvement in outcome could well represent an important advance in our knowledge of the biology of breast cancer and how best to treat it," said Larry Norton, M.D., of Memorial Sloan-Kettering Cancer Center, senior investigator of the study and one of the developers of the original model. (scienceblog.com)
The study involved 248 women, all at different stages of breast cancer treatment. (alive.com)
Fitness level may be an important biomarker of survival among cancer patients," says Lee Jones, PhD, lead author of the study. (alive.com)
Our study included 4,345 women diagnosed with breast cancer (1995-2008) from two population-based studies conducted in the San Francisco Bay Area. (nih.gov)
At AACR, Richard Finn, associate professor of medicine at the University of California, Los Angeles and one of the study investigators, reported that patients in the palbociclib/letrozole combination arm had a median progression-free survival of 20.2 months compared to 10.2 months for those receiving just letrozole. (genomeweb.com)
In this retrospective study, patients living within the Auckland region, diagnosed with ABC between the 1st January 2013 to the 31st December 2015 were identified from the Breast Cancer Registry. (hindawi.com)
Of the 388 patients that met inclusion criteria for this study, median overall survival (medOS) was 18.9 months in the total population, with no difference between patients with de novo metastatic disease (dnMBC -18.9 m) and recurrent metastatic disease (rMBC -18.7 m). (hindawi.com)
This new study follows on from a study conducted by the WHI (Women's Health Initiative), which had found that postmenopausal women eating a low fat diet were less likely to get more aggressive forms of breast cancer. (canceractive.com)
The new study(1) led by Dr. Rowan Chlebowski overcame this and found that women who stuck to the low-fat diet increased their chance of survival from breast cancer by 22% compared to women who remained on a diet higher in fat (a third or more of daily calories from fat). (canceractive.com)
We have reviewed study after study on the effects of high-fat diets, especially high saturated fat diets on cancer prevention, cancer aggression and cancer survival. (canceractive.com)
Women with small social networks and low levels of support were 61 percent more likely to die from breast cancer and other causes than those with small social networks and greater levels of support, the study authors pointed out in the news release. (healthday.com)
The study was published in the current issue of the journal Breast Cancer Research and Treatment . (healthday.com)
While the study found an association between patients' social support networks and survival rates, it did not prove a cause-and-effect relationship. (healthday.com)
In a new observational cohort study, investigators evaluated the association of household income with RS in patients with ER-positive breast cancer. (medpagetoday.com)
This multi-centre study was carried out to further explore the relationship between comorbidities and cancer survival. (wcrf-uk.org)
This particular study was funded by the World Cancer Research International grant programme and by the French National Cancer Institute. (wcrf-uk.org)
This study provides a national overview of breast cancer screening and survival in Aboriginal and Torres Strait Islander women of Australia. (canceraustralia.gov.au)
Cancer Australia (formerly National Breast and Ovarian Cancer Centre*) undertook this study in response to the clear evidence of disadvantage among Aboriginal and Torres Strait Islander peoples compared with other Australians, and the lack of high quality, national breast cancer data available for Aboriginal and Torres Strait Islander women. (canceraustralia.gov.au)
Ranitidine study finds no elevated risk of cancer. (medicalxpress.com)
The number of women in the United States living with distant metastatic breast cancer (MBC) is growing, likely because of an aging population and improvements in treatment, according to a study published online in Cancer Epidemiology, Biomarkers & Prevention . (managedhealthcareexecutive.com)
The study was led by Angela Mariotto, PhD, chief of the Data Analytics Branch of the Division of Cancer Control and Population Sciences at the National Cancer Institute (NCI), with coauthors from NCI, the Metastatic Breast Cancer Alliance, and the Fred Hutchinson Cancer Research Center. (managedhealthcareexecutive.com)
New York, Oct 25 : Men suffering with stage IV breast cancer can increase their survival with surgical intervention, according to a study. (india4u.com)
The study has implications for including vitamin D as an adjuvant to conventional breast cancer therapy," said co-author Heather Hofflich, DO, UC San Diego associate professor in the Department of Medicine. (grassrootshealth.net)
Funding for the study was provided, in part, by a Congressional allocation to the Penn State Cancer Institute of the Milton S. Hershey Medical Center, Hershey, PA, through a cooperative research agreement. (grassrootshealth.net)
One dramatic study showed that green tea tripled the breast cancer survival rate. (green-tea-health-news.com)
A study that looked at nearly 1.9 million people diagnosed with breast cancer found that men have lower overall survival compared to women. (technologynetworks.com)
The study looked at information from 16,025 men diagnosed with breast cancer and 1,800,708 women diagnosed with breast cancer. (technologynetworks.com)
A comparison cohort without cancer was created from the SEER 5% Medicare sample and matched 1:1 to the study cohort based on age, sex, and race. (biomedcentral.com)
Nurgalieva, Zhannat, "Impact of racial differences in medical care on breast cancer survival: Findings from a large nationwide and retrospective cohort study" (2012). (tmc.edu)
This review aimed to identify and summarize the estimated survival statistics from separate sources in the literature and to explore the extent of between-study heterogeneity in survival estimates. (biomedcentral.com)
An exploratory meta-analysis was conducted to describe survival estimates and assess between-study heterogeneity. (biomedcentral.com)
The NPI can be used to provide prognostic information by assigning individuals into prognostic categories and then applying the survival estimates from a previous cohort study [ 11 ]. (biomedcentral.com)
A meta-analysis was used to explore the between-study heterogeneity in survival estimates. (biomedcentral.com)
Based on this study, at least 19% of breast cancer deaths among women in the United States can be estimated to be attributable to nonuse of mammography (Table 2). (cdc.gov)
Nulliparity, decade of first birth, and breast cancer in Connecticut cohorts, 1855 to 1945: an ecological study. (cdc.gov)
A previous study, where using convolutional neural networks (CNN) to classify breast cancer in conventional ultrasound (US) images, showed promising results. (lu.se)
The aim of the present study is to classify POCUS breast images. (lu.se)
It is our expectation that we will integrate findings from this study to establish criteria for identifying and engaging breast cancer patients who are at high risk for leaving to workforce and, based on such findings, develop an empirically-grounded strategy for improving return-to-work in breast cancer patients. (cdc.gov)

A number of 196 patients operated for breast cancer were analyzed by the Kaplan-Meier method over a period of ten years of survival after surgery. (medigraphic.com)
Kaplan-Meier survival analysis was also conducted. (biomedcentral.com)

However, most forms of breast cancer are highly treatable , and the assumption usually is that the sooner it is diagnosed, the more effective the treatment will be. (medicalnewstoday.com)
All the participants who were diagnosed with breast cancer, the investigators note, received the appropriate treatment for the cancer stage they were experiencing, in line with the most recent national guidelines at that time. (medicalnewstoday.com)
Breast cancer survival rates are rising as screening and treatment improve. (medicalnewstoday.com)
A CDK4/6 inhibitor combined with a hormone-blocking drug is now the standard first-line treatment for postmenopausal women with this form of advanced breast cancer, explained Stanley Lipkowitz, M.D., Ph.D., chief of the Women's Malignancies Branch in NCI's Center for Cancer Research. (cancer.gov)
There is much interest in the field of cancer research regarding development of biomarkers to individualize treatment of existing therapies. (news-medical.net)
Demographic, diagnostic, treatment, and survival data were extracted from electronic records for statistical analysis. (hindawi.com)
MacroGenics is also developing margetuximab to evaluate in combination with anti-PD-1 therapy for the treatment of gastroesophageal cancer. (pharmacytimes.com)
Gaining weight during or after treatment for breast cancer increases risk for premature death ( Nutr Cancer , 2015;67:197-202). (drmirkin.com)
This difference persisted across a 10-year span, suggesting that racial inequalities still exist despite great advances in breast cancer treatment options. (cdc.gov)
Improving equity in breast cancer treatment and survival requires a coordinated team approach with doctors, nurses, patient navigators, social workers, and others. (cdc.gov)
Identifying and addressing barriers, educating patients on healthy lifestyles, and improving comorbid conditions can help women have the best opportunity to receive the cancer treatment they need. (cdc.gov)
Bernard Fisher, MD , is recognized today for his groundbreaking research in breast cancer, which ultimately ended the standard practice of performing the Halsted radical mastectomy, a treatment that had been in place for more than 75 years. (ascopost.com)
When the experiment ended, there was 93.8% survival in the green tea extract group compared to only 33.3% survival in the control group that received no treatment. (green-tea-health-news.com)
The 5-year breast cancer survival rate for Stage 1 (Stage I) breast cancer is 98-100% after successful treatment. (green-tea-health-news.com)
Stage 3 (Stage IIIa, IIIb) breast cancer patients face a 5-year survival rate of 49-67% after successful treatment. (green-tea-health-news.com)
Patients are the inspiration behind everything we do, and we will continue to pursue bold treatment advancements that help reimagine the future for people with cancer in hopes that they can live longer, and better. (epicos.com)
Oncological centres should assess BCLM patients more openly and qualify them for hepatic resection along with adjuvant systemic treatment in order to improve overall survival. (aaem.pl)
Triple-negative breast cancer is a rare and aggressive form of breast cancer with fewer treatment options than other breast cancer types. (knowbreastcancer.org)
What is latest treatment for triple-negative breast cancer? (knowbreastcancer.org)
This approval validates sacituzumab as an effective new treatment for patients with triple-negative breast cancer," said Jennifer Matro, M.D., a breast cancer doctor at University of California San Diego Health. (knowbreastcancer.org)
Treatment decisions for male breast cancer are usually based on studies in women. (technologynetworks.com)
Systemic therapies are the recommended primary treatment option for patients with metastatic breast cancer, while surgery is generally considered, if appropriate, after initial systemic therapy [ 4 ]. (biomedcentral.com)
Early detection is a key contributor to better cancer treatment outcome. (who.int)
The benefit of using isoflavone supplements in food or pills in the prevention or treatment of cancer has not been proven. (medlineplus.gov)
My research focuses on neoadjuvant treatment for breast cancer patients. (lu.se)

However, since the combination regimen wasn't statistically significant for improving overall survival in patients compared to the standard arm, the latest data - presented this week at the American Association of Cancer Research annual meeting in San Diego - raised questions from industry observers about how the findings would impact palbociclib's regulatory path. (genomeweb.com)
This is statistically significant and an important median progression-free survival result in the context of current therapies. (genomeweb.com)
However, in the trial, median overall survival in the palbociclib/letrozole arm was 37.5 months compared to 33.3 months for letrozole-only treated patients, not a statistically significant improvement. (genomeweb.com)
Kisqali has shown statistically significant overall survival benefit in two Phase III trials with two distinct patient populations(7,8). (epicos.com)

All Jordanian women newly diagnosed with breast cancer during 1997-98 were included. (who.int)

As described previously ( Rutherford et al, 2013b ), the data were extracted from the (former) Eastern Cancer Registration and Information Centre (ECRIC), a cancer registry covering a population of ∼ 5.7 million across the East of England region. (nature.com)

Exercising for at least 30 minutes every day offers greater survival rates ( Cancer Prev Res , 2011;4:1409-18). (drmirkin.com)
Currently, death rates from breast cancer are declining. (hdkino.org)
That finding, he said, prompted him to question the relationship between 25-hydroxyvitamin D - a metabolite produced by the body from the ingestion of vitamin D - and breast cancer survival rates. (grassrootshealth.net)
Background: Despite improved survival rates for breast cancer the illness exacts a heavy physical toll accompanied by significant disruptions to the psychological and social aspects of everyday life. (cdc.gov)

Interestingly, the metastasis free interval (mFI: 30 months) amongst patients who developed metastatic relapse after early breast cancer was similar to international standards. (hindawi.com)
After that meeting, Dr. Fisher abandoned his research in liver regeneration and transplantation and devoted the next 4 decades to pursuing the biology of breast cancer tumor metastasis and more effective treatments for the disease. (ascopost.com)
With approximately 18,000 new cases of BC diagnosed in Polish women annually, breast cancer liver metastasis (BCLM) is respectively an increasing issue. (aaem.pl)

Also surviving ovarian cancer and lymphedema. (wikipedia.org)
also surviving ovarian cancer) Julia Bradbury (born 1970), Irish-born English television presenter and journalist. (wikipedia.org)
Eating a diet that has a moderate amount of soy prior to adulthood may lower the risk for breast and ovarian cancer in women. (medlineplus.gov)

World Cancer Research Fund is the UK's only charity solely dedicated to cancer prevention and survival. (wcrf-uk.org)

Although targeted therapies are now commonly used for greater survival, using data from the National Cancer Database, even women on these therapies benefitted from increased survival is a mastectomy was performed. (canceractive.com)

Cedric F. Garland, DrPH, and his colleagues at UCSD's Department of Family and Preventive Medicine had previously discovered that low vitamin D levels increase a woman's risk of developing premenopausal breast cancer. (naturalnews.com)

What I mean by that is this is the longest median progression-free survival ever reported in a randomized trial in first-line, ER-positive breast cancer. (genomeweb.com)

In the medical world, there is an ongoing debate about the extent to which regularly screening for breast cancer actually improves a person's chances of survival if cancer is detected. (medicalnewstoday.com)
We need to ensure that participation in breast screening programs improves, especially in socio-economically deprived areas. (medicalnewstoday.com)

For women ages 65 and older diagnosed with small, early-stage, hormone receptor-positive breast cancer, radiation after lumpectomy didn't improve overall survival. (breastcancer.org)

Breast cancer is the 2nd leading cause of cancer death (the most common is lung cancer) in the overall female population but is the leading cause of cancer death in Black women. (msdmanuals.com)

Breast cancer is often diagnosed at later stages and is more aggressive in African American women. (cdc.gov)

Before announcing its decision to drop the mammography guideline for women under age 50, the Office of Cancer Communications (OCC) at the National Cancer Institute (NCI) conducted a series of seven focus groups with obstetrician/gynecologists (ob/gyns) and primary care physicians. (cdc.gov)
Physicians firmly believe that mammography is the only effective means of detecting breast cancer at its earliest possible stage. (cdc.gov)

That approval was based on earlier results from the MONALEESA-2 trial that showed patients treated with ribociclib and letrozole lived longer without their cancer getting worse ( progression-free survival ), compared with those treated with letrozole alone. (cancer.gov)
Socioeconomic status (SES) is a known predictor of health outcome, and studies show that overall, patients with breast cancer who have low SES are at risk of faring worse, regardless of their racial and ethnic backgrounds. (medpagetoday.com)

There were more than 2.26 million new cases of breast cancer in women in 2020. (wcrf-uk.org)
EAST HANOVER, N.J., May 27, 2020 /PRNewswire/ -- Novartis today announced a new exploratory subgroup analysis of the Phase III MONALEESA-3 and MONALEESA-7 trials, to be presented during the ASCO20 Virtual Scientific Program, reinforcing the overall survival (OS) benefit of Kisqali(®) (ribociclib). (epicos.com)

Breast-sparing surgery such as lumpectomy, in which only the cancerous tumor and a small portion of the surrounding tissue are removed, would probably result in similar outcomes but without the disfigurement caused by total mastectomy, reasoned Dr. Fisher. (ascopost.com)
lumpectomy and radiation therapy is considered to be just as effective as mastectomy to treat early-stage breast cancer. (technologynetworks.com)

The National Comprehensive Cancer Network guidelines to treat men with stage IV breast cancer recommends systemic therapy, with surgery used to minimise symptoms such as ulcerations, pain, or bleeding, said first author Kelly A. Stahl, a surgical resident at Penn State College of Medicine. (india4u.com)
Recent data found in literature indicates improved survival following liver resection with systemic therapy. (aaem.pl)

Anatomy11

Organisms3

Diseases41

Chemicals and Drugs46

Analytical, Diagnostic and Therapeutic Techniques and Equipment73

Psychiatry and Psychology3

Phenomena and Processes44

Disciplines and Occupations2

Anthropology, Education, Sociology and Social Phenomena6

Technology, Industry, Agriculture1

Humanities1

Information Science9

Named Groups9

Health Care43

Geographicals17

Chemotherapy36

Advanced or metastatic breast cancer5

European Reference Network for Paediatric Cancers2

20233

Recurrence12

Diagnosis36

Mortality17

Oncology14

Invasive7

Significantly8

20193

Tumors9

Incidence5

Patients with HER2-positive breast cancer1

Researchers20

Abstract1

Diagnosed with localized breast cancer1

Prognosis7

Survivors5

Lymph5

Colorectal cancer2

4,443 breast cancer patients1

Disparities5

Trastuzumab3

HER222

Survivorship4

Poorer3

Clinical12

Metastases4

Outcomes for patients1

Neoplasms2

Five-year survival1

Endocrine therapy1

Characteristics4

Median survival1

Cervical7

Study44

Kaplan-Meier2

Treatment25

Statistically significant4

Newly diagnosed with breast cancer1

Centre1

Rates4

Metastasis3

Ovarian cancer3

Prevention1

Therapies1

Premenopausal1

Longest median1

Improves2

Improve overall survival1

Lung1

Aggressive1

Mammography2

Worse2

20202

Lumpectomy2

Systemic2