POG thus shares pharyngeal pouch-like morphogenesis and a gene expression profile with pharyngeal pouches and can be regarded as a pre-mandibular pharyngeal pouch. (bvsalud.org)
Specific stimuli to plants influence intracellular and intercellular communications, activation of ion channels, gene expression, growth and development. (bvsalud.org)
Cell differentiation involves profound changes in global gene expression that often has to occur in coordination with cell cycle exit. (farinaslab.com)
Because cyclin-dependent kinase inhibitor p27 reportedly regulates proliferation of neural progenitor cells in the subependymal neurogenic niche of the adult mouse brain, but can also have effects on gene expression, we decided to molecularly analyze its role in adult neurogenesis and oligodendrogenesis. (farinaslab.com)
By integrating genome-wide gene expression and chromatin accessibility data, we find that p27 is coincidentally necessary to repress many genes involved in the transit from multipotentiality to differentiation, including those coding for neural progenitor transcription factors SOX2, OLIG2 and ASCL1. (farinaslab.com)