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  • surgical
  • The book opens with a series of chapters on underlying principles and diverse relevant topics, including pathologic anatomy of early-stage breast cancer, radiobiology of accelerated breast irradiation, quality assurance and radiation safety, surgical considerations in partial breast irradiation, and impact of oncoplastic surgery on adjuvant radiotherapy. (abebooks.com)
  • treatment
  • Published in the journal Molecular Cancer Therapeutics , the study builds on the research of principal investigator Kristoffer Valerie, Ph.D., and has paved the way for a phase 1 clinical trial testing a similar but more effective experimental drug, AZ1390, in combination with radiation therapy for the treatment of brain cancer. (vcu.edu)
  • This study laid the groundwork for a phase 1 clinical trial ( NCT03423628 ) led by AstraZeneca that will test AZ1390 in combination with radiation therapy for the treatment of brain tumors. (vcu.edu)
  • In some cases, participation in a clinical trial utilizing new, innovative radiation techniques may provide the most promising treatment. (texasoncology.com)
  • The information on this website is intended to help educate patients about their treatment options and to facilitate a mutual or shared decision-making process with their treating cancer physician. (texasoncology.com)
  • While EBRT is the conventional treatment for brain tumors, SRT has also become a standard procedure. (texasoncology.com)
  • EBRT begins with a planning session, or simulation, during which the radiation oncologist places marks on the body and takes measurements in order to line up the radiation beam in the correct position for each treatment. (texasoncology.com)
  • During treatment, the patient lies on a table and the radiation is delivered from multiple directions. (texasoncology.com)
  • The actual area receiving radiation treatment may be large or small, depending on the features of the cancer. (texasoncology.com)
  • 25% increase in contrast enhancing tumor volume documented at the initiation of treatment on protocol. (clinicaltrials.gov)
  • Complete response is complete resolution of all contrast enhancing tumor documented at initiation of treatment on protocol, with no appearance of new lesions. (clinicaltrials.gov)
  • This is a common treatment for brain tumors. (denverhealth.org)
  • Available at: https://www.cancer.gov/types/brain/patient/child-brain-treatment-pdq. (epnet.com)
  • Learn about side effects, what to expect before, during and after treatment and resources to help you during your cancer journey. (merlot.org)
  • This ten-and-a-half minute video gives a general overview of radiation therapy as used for brain tumors and walks a patient visually through the simulation and treatment process, with explanations of everything involved. (merlot.org)
  • Each patient who comes to MD Anderson's Brain and Spine Center for brain tumor treatment receives customized care from some of the nation's top experts. (mdanderson.org)
  • Treatment depends on the type, size, location of the cancer, and your overall health. (portsmouthhospital.com)
  • The treatment is used to prevent brain tumors. (portsmouthhospital.com)
  • ALL is the most common malignancy in the pediatric population, and [its treatment] is really one of the great success stories in all of cancer therapies," noted James R. Downing, MD , Scientific Director and Deputy Director of St. Jude Children's Research Hospital in Memphis. (ascopost.com)
  • My experience with her treatment helped me this past year when my dog developed nasal cancer, I opted to do palliative radiation and was lucky to find a vet oncologist that was wanting to try IMRT radiation ( not quite cyberknife but is a little similar ) So yes I went for the IMRT. (healthboards.com)
  • Daniel Haber, MD, PhD, director of the MGH Cancer Center, outlined current opportunities and challenges in cancer research and treatment, and provided a vision to meet them during a presentation at the 13th annual Phillips Society luncheon Sept. 7. (massgeneral.org)
  • UPTON, NY - A promising brain tumor therapy now in clinical trials at the U.S. Department of Energy's Brookhaven National Laboratory will have added cancer-treatment potential, thanks to a $1.4 million award to improve the facility used to deliver the therapy. (bnl.gov)
  • Many cancer patients want to see the Laboratory deliver on the promise of this treatment. (bnl.gov)
  • Conventional radiation therapy also requires several bouts of treatment, an inconvenience for many patients. (bnl.gov)
  • Radiation-induced gastrointestinal morbidity for the treatment of pelvic and abdominal tumors is more common than generally recognized and can negatively impact the patient's quality of life. (hindawi.com)
  • In the first stage of the study, treatment with G207 will be followed by focal radiation therapy on the following day, and in the second stage treatment with G207 will be followed by gamma knife surgery also on the following day. (clinicaltrials.gov)
  • Availability of new treatment options for brain tumors and neurological cancers within our clinical trials program . (emory.edu)
  • It uses protons to precisely treat cancerous tumors throughout the body and can be more precise than conventional forms of radiation treatment. (emory.edu)
  • There are many methods available for the treatment of this type of cancer. (newhealthguide.org)
  • Dr Arthur's primary research interests include clinical studies focusing on the treatment of breast cancer with special interest in the development and use of accelerated treatment for breast cancer. (abebooks.com)
  • He is involved in numerous clinical studies being the Principal Investigator of several with the goal of improving therapeutic outcomes for all stages of breast cancer, reducing cancer treatment times and minimizing toxicities of healthy tissues and vital organs. (abebooks.com)
  • What is the treatment for intracardiac tumor? (healthtap.com)
  • Children who received radiation therapy on this study were evaluated for treatment failure at 12 months. (clinicaltrials.gov)
  • In addition to the primary objective, the study was designed to explore the association between radiation dose and volume and a variety of neurological, endocrine and cognitive deficits up to 5 years after treatment. (clinicaltrials.gov)
  • There are some known cognitive effects from radiation treatment, including short-term memory loss and difficulties in school, but no one had really looked at this retention of biographical information," said study author Melanie Sekeres. (hon.ch)
  • Radiation is typically a major part of treatment. (hon.ch)
  • He said a next step is to determine what rehabilitation tools and techniques might help young survivors improve thinking skills affected by radiation treatment. (hon.ch)
  • Diagnostic Radiology answers the challenge to 'see' cancer inside a patient's skull or spine, crucial for accurate diagnosis and treatment. (mdanderson.org)
  • For three decades, standard treatment has been to expose the entire breast to radiation beams daily, Monday through Friday, for between three to six weeks, said co-lead researcher Dr. Julia White. (healthday.com)
  • Advances in early detection and radiation therapy led White and her colleagues to ask if a shorter, more intense round of treatment might do just as well in women whose breast cancer had been caught early. (healthday.com)
  • But in a certain group of women who were at very low risk -- over age 50, with hormone-sensitive tumors and lymph nodes showing no signs of the cancer spreading -- the partial-radiation therapy performed just as well as traditional treatment, White said. (healthday.com)
  • A total of 56 patients receiving proton radiation for treatment of brain tumors were enrolled on this study. (oncolink.org)
  • They note that these results compare favorably to previous reports from photon radiation treatment in pediatric brain tumor patients. (oncolink.org)
  • cancerous
  • The point of the NTP study was to find out if simulated cellphone RFR could possibly produce a cancerous tumor. (psychologytoday.com)
  • A lack of consistent evidence in human-centered epidemiological studies has encouraged a passive response to the NTP findings, largely because there has not been an overall increase of cancerous brain tumors observed since cellphone ownership skyrocketed (though some research has shown tumor-rate increases in areas of the brain next to where people hold their phone). (psychologytoday.com)
  • patients
  • As many as 80 percent of GBM patients have cancers with mutant or dysfunctional p53 signaling. (vcu.edu)
  • The trial is now enrolling and estimated to register 132 patients at seven medical centers in the US and the UK, including VCU Massey Cancer Center. (vcu.edu)
  • Planning was retrospectively performed on 12 brain tumor and 10 post-prostatectomy prostate patients previously treated with MCO-IMRT. (springer.com)
  • Patients will receive radiation therapy to the brain once a day, Monday through Friday, for 6 1/2 weeks. (clinicaltrials.gov)
  • Your gift will help support our mission to end cancer and make a difference in the lives of our patients. (mdanderson.org)
  • This gives us a level of expertise and experience that can translate into more successful outcomes for many brain tumor patients. (mdanderson.org)
  • We're studying new ways to prevent and treat brain tumors to give patients everywhere futures filled with hope. (mdanderson.org)
  • Sometimes, patients being treated with radiation to the brain are taking steroid medications to prevent or reduce swelling (decadron/dexamethasone, for instance). (oncolink.org)
  • This randomized phase II trial is studying how well bevacizumab works in reducing CNS side effects in patients who have undergone radiation therapy to the brain for primary brain tumor, meningioma, or head and neck cancer. (clinicaltrials.gov)
  • I. Determine to what extent bevacizumab can reduce active radiation toxicity to the CNS in patients who have undergone cranial irradiation for primary brain neoplasm, meningioma, or head and neck cancer. (clinicaltrials.gov)
  • Our Mission: To advance knowledge and rapidly translate discovery into exceptional, personalized cancer care for our patients. (massgeneral.org)
  • Newton-Wellesley Hospital (NWH) has recently expanded its partnership with the Mass General Cancer Center (MGCC) to provide NWH patients access to the entire team of MGCC experts including specialists. (massgeneral.org)
  • So far, BNL has treated 38 patients diagnosed with a lethal form of brain cancer known as glioblastoma multiforme, which strikes more than 7,000 Americans each year. (bnl.gov)
  • The majority of the patients treated with BNCT at BNL to date have received relatively low doses of radiation. (bnl.gov)
  • Modulation of these processes is of particular importance with regard to increasing the therapeutic outcome for cancer patients. (hindawi.com)
  • These research articles are followed by five reviews that demonstrate the potential ability of PPARs to increase the therapeutic window for cancer patients. (hindawi.com)
  • In the US approximately 62% of adult and over 75% of pediatric cancer patients survive beyond 5 years. (hindawi.com)
  • In emails released with the report, Accretive workers talked about the need to "get cracking on labor and delivery" and celebrated the launch of a new collection process for breast cancer patients. (mercola.com)
  • It's a challenge dealing with these patients because it's the nature of these tumors that they will recur. (ucsf.edu)
  • All of these are being fostered at Emory and are offered whenever possible to patients with nervous system tumors to assist in the development of these technologies. (emory.edu)
  • This finding suggests a novel therapeutic target to decrease invasion of tumor cells in patients and may also provide a novel biomarker that could help predict survival of patients with glioblastoma," explained Israel. (medicalxpress.com)
  • Using data from The Cancer Genome Atlas (TCGA), the Dartmouth team demonstrated that Id4 expression correlates with survival of glioblastoma patients and inversely correlates with MMP2 expression. (medicalxpress.com)
  • Targeting Twist1 might silence MMP2 and decrease tumor invasion, which will help patients with GBM. (medicalxpress.com)
  • Their pursuit of Id4 as a biomarker for patients with GBM continues in hopes of making useful predictions of tumor invasion and survival. (medicalxpress.com)
  • Why Do Cancer Patients Lose Weight? (newhealthguide.org)
  • RATIONALE: Donepezil may help lessen confusion and fatigue and improve mood and quality of life in patients who have undergone radiation therapy for brain tumors. (clinicaltrials.gov)
  • It is not yet known whether donepezil is more effective than a placebo in lessening side effects of radiation therapy in patients with brain tumors. (clinicaltrials.gov)
  • PURPOSE: This randomized phase III trial is studying donepezil to see how well it works in lessening side effects of radiation therapy compared with a placebo in patients who have undergone radiation therapy for brain tumors. (clinicaltrials.gov)
  • Compare the effect of donepezil hydrochloride vs placebo, in terms of improving neurocognitive symptom cluster (i.e., cognitive impairment, subjective confusion, and fatigue), in patients who have undergone partial- or whole-brain irradiation for brain tumors. (clinicaltrials.gov)
  • Patients are stratified according to prior brain irradiation type (whole-brain vs partial-brain) and study site. (clinicaltrials.gov)
  • The current study was performed to examining long-term neurocognitive outcomes of 56 patients with various brain tumors treated with proton radiation at MGH. (oncolink.org)
  • What is the neurocognitive profile of pediatric brain tumor patients before and after radiation therapy? (oncolink.org)
  • This is a longitudinal study that examined the neurocognitive and academic function in184 patients with brain tumors who received proton radiation using a multitude of standardized assessment tools with age-based scores. (oncolink.org)
  • In terms of histology, a larger IQ decline was seen for patients with medulloblastoma compared to those with other brain tumors, likely because medulloblastoma patients received CSI. (oncolink.org)
  • primary tumor
  • Key brain regions that we know are typically involved in autobiographical memory formation and retrieval, especially the hippocampus, are located quite far from the primary tumor bed, and thus far from the site of focal radiation," Sekeres, who is director of the Sekeres Memory Laboratory at Baylor University, said in an interview with CURE . (curetoday.com)
  • therapies
  • Stephen Elledge, PhD, and his team did not set out to find therapies that could render tumors less resistant to therapy or make existing drugs more potent against a rare form of cancer. (cshlpress.com)
  • Access to the Brain and Spine Tumor Support Group at Winship where you and your caregivers can learn about current therapies and share your experiences. (emory.edu)
  • Winship's most promising research in treating brain and spinal cord tumors is in personalized medicine and targeted therapies. (emory.edu)
  • In targeted therapies, investigators look for new drugs that selectively target cancer cells with fewer side effects. (emory.edu)
  • This type of imaging is more sensitive and accurate in measuring the extent of disease, understanding the cell signaling that controls cancer growth, identifying molecular targets for anti-cancer therapy and monitoring these molecular and cellular therapies. (mdanderson.org)
  • oncologist
  • The main citation for this claim is a Swedish oncologist named Lennart Hardell, who found in one study that talking on a mobile or cordless phone could triple the risk of "a certain kind of brain cancer ," Bilton says. (slate.com)
  • Overall an excellent book for the shelves of every evidenced base breast radiation oncologist. (abebooks.com)
  • Dr. Richard Bakst, a radiation oncologist at Mount Sinai in New York City, said he's concerned about how well the technique compares to full-breast radiation. (healthday.com)
  • dose
  • I have worked in the area of the health effects of ionizing radiation, especially at low doses and slow dose rates, for the past 30 years and have produced and published books, and professional papers,,,, on the subject. (ccnr.org)
  • First, dose reconstruction does nothing to prove or disprove that a veteran's cancer or disease is related to their nuclear radiation exposure. (ccnr.org)
  • In effect, hiring the government's radiation protection community to prepare dose reconstructions to replace the records which were lost is like asking the tax payer to guess his or her income which should be the basis of back taxes! (ccnr.org)
  • Furthermore, there is no scientific evidence that a limiting dose of radiation exists below which there is little or no risk of developing a cancer or other health problem. (ccnr.org)
  • In fact, there is peer reviewed published research which shows that excess cancers have occurred at dose levels which are within the maximum permissible dose levels set for workers and members of the public. (ccnr.org)
  • Machines called linear accelerators produce the high-energy radiation beams that penetrate the tissues and deliver the radiation dose directly to the cancer. (texasoncology.com)
  • The therapy is now being tested under a Phase I/II dose-escalation protocol approved by the U.S. Food and Drug Administration to determine the best doses of radiation and boron compound to use. (bnl.gov)
  • In the current trial, the radiation doses are being increased step-by-step as soon as the safety of a given dose is reasonably assured. (bnl.gov)
  • Local failure included tumor progression within the volume that received the prescribed dose of irradiation. (clinicaltrials.gov)
  • This is due to its characteristic Bragg Peak, which allows maximal deposition of dose in tumor, without an exit dose. (oncolink.org)
  • Imaging
  • Follow-up includes a physical examination, blood tests and magnetic resonance imaging of the brain. (clinicaltrials.gov)
  • Earlier detection of tumor growth or useful response to therapy are the goals of new imaging methods including magnetic resonance spectroscopy, magnetic resonance spectroscopic imaging, and new tracers for positron emission tomography. (emory.edu)
  • Intracardiac tumors are almost always discovered on imaging studies, typically ultrasound, because of a new murmur or impaired heart function. (healthtap.com)
  • Imaging studies demonstrating tumor progression were electronically registered to the imaging data used to plan therapy. (clinicaltrials.gov)
  • Cancer Systems Imaging focuses on imaging at the cellular and molecular level. (mdanderson.org)
  • penetrate
  • Our study is the first to show that an ATM kinase inhibitor that can be taken orally and able to penetrate the blood- brain barrier radiosensitizes GBM in mouse models. (vcu.edu)
  • Dr. Keith Black, a world-renowned brain surgeon and researcher at the Cedars-Sinai Medical Center in Los Angeles, has said that the microwave radiation that is generated from cell phones can penetrate the brain when held directly to the ear. (consumeraffairs.com)
  • recurrence
  • Lybarger said her tumor wound up being around 1.4 centimeters when surgically removed, and genetic testing showed she was at low risk for recurrence. (healthday.com)
  • suppressor
  • The combination of AZ32 and radiation was highly effective against GBM cells with mutant versions of the p53 tumor suppressor gene, which normally acts to promote radiation resistance. (vcu.edu)
  • outcomes
  • This sets us apart from many other cancer centers and helps us target each tumor for optimal outcomes. (mdanderson.org)
  • Our doctors have performed more than 10,000 brain surgeries with a strong outcomes record. (vanderbilthealth.com)
  • Outcomes for children with cancer have "improved over the course of the years incrementally, mostly not from the development of new drugs, because virtually all the drugs that we use now in leukemia were available in the 1970s. (ascopost.com)
  • surgery
  • BNCT is given only after the patient has undergone surgery to remove the bulk of the tumor. (bnl.gov)
  • selectively
  • It is also the first to explain the p53-based mechanism by which ATM kinase inhibitors selectively sensitize brain cancers to radiation," says Valerie. (vcu.edu)
  • Importantly, ZIKV-LAV significantly reduced intracerebral tumor growth and prolonged animal survival by selectively killing GSCs within the tumor. (asm.org)
  • blood- brain
  • This time with AZ32, we used an ATM kinase inhibitor that penetrates the blood-brain barrier. (vcu.edu)
  • Dysfunction of the blood brain barrier due to radiation has been reported in animals, which could allow leakage of cancer-causing substances into brain. (mdanderson.org)
  • PPAR agonists can cross the blood brain barrier, have well-described anti-inflammatory and neuroprotective properties, and as reported in this review do appear to modulate late radiation-induced brain injury, including cognitive impairment, in rodent models. (hindawi.com)
  • resistance
  • The necessary presence of S100A2 for the maximum antiproliferative effect of PPARs indicates a potential mechanism of tumor response or resistance to PPAR -directed anticancer therapy. (hindawi.com)