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  • Diagnosis
  • In many cases, initial biopsy of the brain lesion is required, since definitive diagnosis forms the foundation for treatment decision-making. (readbyqxmd.com)
  • solid tumors
  • Targeted PE-cytotoxins have been used as antitumor agents, although their effective clinical translation in solid tumors has been confounded by off-target delivery, systemic toxicity, and short chemotherapeutic half-life. (sigmaaldrich.com)
  • researchers
  • But UCSF researchers are working on another angle of stem cell research -- one focused on illuminating disease. (ucsf.edu)
  • According to a study carried out on mice published today in the British publication NatureAn, an international team of researchers has programmed nanorobots to search for, and destroy tumors by cutting off their blood supply. (emaxhealth.com)
  • To more accurately reflect the mechanisms driving oligodendrogliomas, the researchers used RNA sequencing to study directly, on a single-cell level, gene expression in samples from six early-stage human tumors. (medicalxpress.com)
  • etiology
  • 00:00:29.27 with a special focus on the cancer brain tumors, 00:00:32.17 the possible etiology of some of these tumors, 00:00:36.09 as well as the future research that my group, as well as other groups around the world, 00:00:41.16 are conducting on this disease. (ibiology.org)
  • neural
  • In the current review article, the team examined a body of evidence that they say signals a watershed moment in the convergence of neural stem cell research and brain tumor research. (ucsf.edu)
  • surgical
  • For Sangita's treatment, keeping the age factor and advanced complications in mind, the team of doctors at Venkateshwar Hospital decided to go for a Radio Surgery, new-age surgical procedure where the skull does not have to be opened to treat the tumor. (business-standard.com)
  • We don't know yet if the response would be strong enough to prevent a tumor from coming back, but we now have a human clinical trial underway to assess safety for further study," said John Yu, MD, vice chair of the Department of Neurosurgery, director of surgical neuro-oncology, medical director of the Brain Tumor Center and neurosurgical director of the Gamma Knife Program at Cedars-Sinai. (eurekalert.org)
  • oncogenes
  • Perform analysis of mutations in candidate tumor-suppressor genes and oncogenes (including whole genome sequencing studies) using direct sequence analysis of tumor DNA and confirm the tumor-specific nature of these mutations by analyzing the correspondent constitutional DNA. (clinicaltrials.gov)
  • diagnosis
  • I was really sad when I heard about John McCain's diagnosis with a glioblastoma, a particularly nasty type of brain tumor that we study in my lab when it shows up in children. (ipscell.com)
  • Immunohistochemical analysis, cytogenetic and molecular genetic findings, and measures of mitotic activity are increasingly used in tumor diagnosis and classification. (wellspan.org)
  • therapies
  • Trying to understand as much as we can about genetic versus non-genetic determinants of tumor organization is key to our understanding of tumor propagation and to the design of new therapies. (medicalxpress.com)
  • type
  • 00:03:10.11 Yet, we can still achieve cures in some of these tumors, 00:03:16.23 if they are the non-cancerous type. (ibiology.org)
  • 00:04:01.05 Yet, some of these challenging tumors, if they are the non-cancerous type, 00:04:06.15 they can still be cured with surgery. (ibiology.org)
  • Children with neurofibromatosis type 1 (NF1) are at an increased risk of developing a brain stem glioma. (wellspan.org)
  • scientists
  • Scientists are studying the earliest stages of embryonic and adult stem cell growth in the culture dish and in animal models with the ultimate goal of identifying the genetic missteps that cause such diseases as amyotrophic lateral sclerosis (ALS), and that account for some cases of birth defects and infertility. (ucsf.edu)
  • Donate
  • Donate now during the month of May and help us support local families who have a child being treated for brain cancer. (kyleoc.org)
  • adult
  • Apparently this is quite rare as an adult (41yo F) to have one of these and on the brain stem and the growth habit was surprising to the Drs also. (btsurvivor.com)
  • cell
  • Our results suggested that CD133 was more specifically expressed as a cancer stem cell marker than nestin, but may not always be an information marker for WHO grading. (aacrjournals.org)
  • The team published the results of their work in the journal Cell Stem Cell. (cancerresearchuk.org)
  • Dr Pollard and his team have investigated their new cancer stem cell lines in depth, assessing the molecules found within them, and looking for genetic abnormalities linked to the cancer. (cancerresearchuk.org)
  • The team found that 38 drugs had some effect on at least one cell line, including a number of drugs that affect neurotransmitters (chemicals that send signals within the brain) - particularly the serotonin pathway . (cancerresearchuk.org)
  • But below the public radar screen is another element of stem cell research -- one focused on illuminating disease. (ucsf.edu)
  • In sum, integrating stem cell-based engineering, multimodal imaging, and delivery of PE-cytotoxins in a clinically relevant GBM model represents a novel strategy and a potential advancement in GBM therapy. (sigmaaldrich.com)
  • embryonic
  • Sonic hedgehog plays an important role during the embryonic development of the brain, but normally shuts down when its no longer needed. (emaxhealth.com)