• More than 3 decades ago, pioneering studies that transplanted stem cells to treat Parkinson's used "fetal cells obtained from the midbrain of aborted embryos. (medicalnewstoday.com)
  • The body's visual and auditory reflex centers are situated in the part of the brain stem called the midbrain. (reference.com)
  • The inferior colliculus, is the principal midbrain nucleus of the auditory pathway and receives input from several peripheral brainstem nuclei, as well as inputs from the auditory cortex. (wikipedia.org)
  • The lateral lemniscus is a tract of axons in the brainstem that carries information about sound from the cochlear nucleus to various brainstem nuclei and ultimately the contralateral inferior colliculus of the midbrain. (wikipedia.org)
  • Basal view of a human brain Dissection of human midbrain with middle cerebellar peduncle labeled. (wikipedia.org)
  • In the human brain, the superior cerebellar peduncle (brachium conjunctivum) is a paired structure of white matter that connects the cerebellum to the midbrain. (wikipedia.org)
  • Supratentorial herniation Uncal (transtentorial) Central Cingulate (subfalcine/transfalcine) Transcalvarial Tectal (posterior) Infratentorial herniation Upward (upward cerebellar or upward transtentorial) Tonsillar (downward cerebellar) In uncal herniation, a common subtype of transtentorial herniation, the innermost part of the temporal lobe, the uncus, can be squeezed so much that it moves towards the tentorium and puts pressure on the brainstem, most notably the midbrain. (wikipedia.org)
  • The new findings "extend the scope of neural stem cell therapy to include their use as vehicles for protein delivery to glioma," they say. (newscientist.com)
  • The difference is crucial for scientists who often prefer to capture only uncommitted neural stem cells, whether to treat brain diseases requiring the replacement of multiple cell types or to better understand their function. (medicalnewstoday.com)
  • New research , which now appears in a special supplement to the Journal of Parkinson's Disease , evaluates the potential of stem cell therapy for treating this neurodegenerative condition. (medicalnewstoday.com)
  • Recent advances in stem cell technology mean that the materials from which stem cells are derived are different and varied. (medicalnewstoday.com)
  • We are moving into a very exciting era for stem cell therapy," Prof. Parmar points out. (medicalnewstoday.com)
  • The first-generation cells are now being trialed and new advances in stem cell biology and genetic engineering promise even better cells and therapies in the future. (medicalnewstoday.com)
  • Prof. Parmar goes on to point out that "[t]here is a long road ahead in demonstrating how well stem cell-based reparative therapies will work, and much to understand about what, where, and how to deliver the cells, and to whom. (medicalnewstoday.com)
  • DRESDEN, Germany, February 5, 2014 -- Scientists here recently discovered a new mechanism governing brain stem cell proliferation. (thefreedictionary.com)
  • UCSF scientists have discovered a new stem cell in the developing human brain. (redorbit.com)
  • This discovery has the potential to transform our understanding of the development and evolution of the human neocortex, the most uniquely human part of the central nervous system," says the senior author of the study, neurologist Arnold Kriegstein, MD, PhD, director of the Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research at UCSF. (redorbit.com)
  • They characterized two kinds of cells within the region""both the novel neural stem cell and its daughter cell, known as the transit amplifying cell. (redorbit.com)
  • The stem cell undergoes asymmetrical cell division, giving rise to two distinct daughter cells""one a copy of the original stem cell, the other a transit amplifying cell. (redorbit.com)
  • We suspect that faults in cell-cycle regulation account for a variety of developmental brain diseases. (redorbit.com)
  • Each stem cell has its own identity, depending on its location in the subventricular zone. (eurekalert.org)
  • When the animals fasted, the activity of the nerve cells in the hypothalamus decreased and with it also the rate of proliferation in the targeted stem cell population. (eurekalert.org)
  • But many early methods used viruses to permanently incorporate new genes into the DNA of the cells, wrote Kristen Brennand, a stem cell researcher at the Mount Sinai School of Medicine, who was not involved in the study, in an email. (livescience.com)
  • The transformation from kidney cell to brain stem cell took just 12 days, and within a month, the cells had morphed into full-fledged brain cells. (livescience.com)
  • From this research, we knew that when stem cells detach from their niche, they lose their identity as stem cells and begin to differentiate into specific cell types," said co-senior author Antonio Iavarone, MD, professor of Pathology and Neurology at CUMC. (eurekalert.org)
  • However, the pathways that regulate the interaction of stem cells with their niche were obscure," said co-senior author Anna Lasorella, MD, associate professor of Pathology and Pediatrics at CUMC and a member of the Columbia Stem Cell Initiative. (eurekalert.org)
  • In the brain, the stem cell niche is located in an area adjacent to the ventricles, the fluid-filled spaces within the brain. (eurekalert.org)
  • In previous studies, Drs. Iavarone and Lasorella focused on molecules called Id (inhibitor of differentiation) proteins, which regulate various stem cell properties. (eurekalert.org)
  • They undertook the present study to determine how Id proteins maintain stem cell identity. (eurekalert.org)
  • Their brains showed markedly lowered NSC proliferative capacity, and their stem cell populations were reduced. (eurekalert.org)
  • However, our findings suggest that stem cell identity relies on this mechanism. (eurekalert.org)
  • If we can understand how to manipulate the pathways that determine stem cell fate, in the future we may be able to control NSC properties for therapeutic purposes. (eurekalert.org)
  • Another aspect," added Dr. Lasorella, "is to determine whether Id proteins also maintain stem cell properties in cancer stem cells in the brain. (eurekalert.org)
  • We show that endothelial cells interact closely with self-renewing brain tumor cells and secrete factors that maintain these cells in a stem cell-like state. (nih.gov)
  • Hit 'em where they live: targeting the cancer stem cell niche. (nih.gov)
  • This detailed volume compiles the best methodologies and experimental techniques to profile and extract maximal data from brain tumor stem cells (BTSCs), the experimental paradigm for brain cancer research that offers insights into cancer stem cell populations that may drive not only tumor initiation but tumor recurrence and patient relapse. (springer.com)
  • Other markers of stem cell function remain to be investigated, including ability to differentiate and migrate. (medpagetoday.com)
  • To stave off cancer stem cell growth in the brain, Dr. John Boockvar is studying two drugs already available for cancer treatment. (news-medical.net)
  • A glioma is a tumor that grows from a glial cell, which is a supportive cell in the brain. (cancer.net)
  • Principal investigator Silvia Marino, Professor of Neuropathology at Queen Mary, University of London, and her team showed that medulloblastomas can grow from a type of brain stem cell and that these cancers are a distinct form of the disease which may require a completely different approach to treatment. (medindia.net)
  • The cancer stem cell model proposes a clonally derived brain tumor arising from a cancer stem cell. (nih.gov)
  • The tumor cells differentiate unidirectionally from the cancer stem cell in a way parallel to normal development. (nih.gov)
  • One type of stem cell can produce multiple types of nerve cells at different stages of the brain's development. (eurekalert.org)
  • In this process, ageing stem cells also gradually become more limited in their development potential and lose the ability to develop the maturated cell types that form during the early stages. (eurekalert.org)
  • How neural stem cell identity and potential is regulated over time has been poorly understood. (eurekalert.org)
  • TGF-beta functions as an important time signal that controls when a stem cell should stop producing one type of nerve cell and instead start producing another, while also gradually limiting the stem cell's future development capacity," says Johan Ericson, Professor of Developmental Biology, who led the study. (eurekalert.org)
  • That figure goes up to 15 million worldwide, with a large portion of them suffering irreversible damage - the type which the stem cell injections set out to cure. (rt.com)
  • The mice regained lost skills after the stem-cell treatment. (technologyreview.com)
  • Rob Coppes , a radiation and stem-cell biologist at the University Medical Center Groningen, in the Netherlands, says he would next like to see Limoli test how long the benefits of the stem cells last. (technologyreview.com)
  • The research team at Kyoto University injected induced Pluripotent Stem (iPS) cells which have the potential to develop into any cell in the body into the brain of a male patient in his fifties, the university said in a press release. (freerepublic.com)
  • One month after stem-cell implantation, irradiated rats' performance on standardized tasks was similar to that of control animals not exposed to cranial irradiation. (medpagetoday.com)
  • To determine the potential of neural stem cell transplantation to reverse radiation-induced cognitive impairment, the authors conducted a study involving three groups of laboratory rats. (medpagetoday.com)
  • Two groups of animals underwent cranial irradiation, followed by human neural stem cell transplantation into the hippocampus or a sham transplant procedure. (medpagetoday.com)
  • One and four months after transplantation, investigators assessed stem-cell survival and phenotypic fate, as well as the rats' cognitive function. (medpagetoday.com)
  • The capability to minimize the adverse cognitive sequelae associated with cranial radiotherapy is encouraging and points to the promise of using stem-cell-based strategies or minimizing normal tissue damage," they added. (medpagetoday.com)
  • Since the process only involves a single gene, it is highly amenable for the development of drugs targeted at promoting stem cell differentiation in the adult nervous system. (rxpgnews.com)
  • The study, published in Nature Neuroscience , reveals a novel gene regulatory system that may advance stem cell therapies and gene-targeting treatments for neurological diseases such as Alzheimer's disease, Parkinson's disease, and mental health disorders that affect cognitive abilities. (eurekalert.org)
  • As NSCs are increasingly explored as a cell replacement therapy for neurological disorders, understanding the basic biology of NSCs--including how they self-renew--is essential to harnessing control of their in vivo functions in the brain. (eurekalert.org)
  • In Aim 1, we will map the domains of stem cell activation and cell types generated in different states in male and female mice. (europa.eu)
  • In Aim 2, we will perform large-scale single cell sequencing to decode stem cell heterogeneity and develop novel fate mapping strategies to selectively target different stem cell populations. (europa.eu)
  • In Aim 3, we will define how the choroid plexus and long- range innervation differentially affect V-SVZ stem cell recruitment in different states using approaches to manipulate neural circuit activity. (europa.eu)
  • Together these experiments will provide a conceptual breakthrough into illuminating the logic of adult neural stem cell heterogeneity, and how regionally distinct adult neural stem cells integrate long-range signals from remote brain areas to respond to signals for on-demand neurogenesis or gliogenesis. (europa.eu)
  • The research, published July 11 in the journal Stem Cell Reports , opens possibilities for effectively guiding stem cells to repair brain damage. (eurekalert.org)
  • Feng and Zhao developed a model of stem cell transplants in rats. (eurekalert.org)
  • These cells possess the unique ability to produce multiple differentiated cell types within the brain, but they are usually in an inactive or "sleep" state referred to as quiescence. (news-medical.net)
  • This stem cell possesses higher regenerative potential than previously identified quiescent stem cells. (news-medical.net)
  • The study, conducted by UCI scientists LaFerla, professor of neurobiology and behaviour, Mathew Blurton-Jones and Tritia Yamasaki, was performed using a new type of genetically engineered mouse that developed brain lesions in areas designated by the scientists and found that mice with brain injuries experienced enhanced memory up to three months after receiving a stem cell treatment. (thaindian.com)
  • The next step is to try to control and enhance stem cell self-healing properties with the aimof carrying out therapies targeted to a specific area of the brain. (medindia.net)
  • The results contribute to better understanding of how brain cell plasticity works and opens up new opportunities to exploit these very features. (medindia.net)
  • Preferred Term is Hematopoietic stem cell transplantation. (medindia.net)
  • In this stem cell from bone marrow are injected into a recipient after treating them with growth factor. (medindia.net)
  • Most everyone has heard about the controversy surrounding stem cell research and treatment. (brainandspinalcord.org)
  • It seems like just about every media outlet-magazines, newspapers, television-has played host to the debate regarding whether stem cell research and treatment are moral and/or ethical. (brainandspinalcord.org)
  • Secondly, opponents are concerned about the health and safety of the participants in human stem cell research trials. (brainandspinalcord.org)
  • Stem cell research came on the scene in 1998, when a group of scientists isolated pluripotent stem cells from human embryos and grew them in a culture. (brainandspinalcord.org)
  • Stem Cells Translational Medicine , "Identification of novel HLA-A*0201-restricted, cytotoxic T lymphocyte epitopes on CD133 for cancer stem cell immunotherapy," Available online 12/27/13. (eurekalert.org)
  • The research team led by Fueyo, co-senior author Frederick Lang, M.D., professor in M. D. Anderson's Department of Neurosurgery, and first author Hong Jiang, Ph.D., instructor in neuro-oncology, derived four brain tumor stem cell lines from four specimens of glioblastoma multiforme. (eurekalert.org)
  • However, the optimal conditions of stem cell use are still being determined. (mdpi.com)
  • We recognize that stem cell derivations also provide uniquely individual difficulties and limitations in their therapeutic applications. (mdpi.com)
  • The new research, published in the journal Cell Stem Cell , is a collaboration between Dr. Gad Vatine of BGU's Regenerative Medicine and Stem Cell Research Center and Department of Physiology and Cell Biology and Dr. Clive N. Svendsen, of Cedars-Sinai Medical Center in Los Angeles. (mddionline.com)
  • He asked whether and what stem cell therapies may be beneficial for his condition. (rutgers.edu)
  • There is no credible data and no stem cell therapy has been shown to restore function yet in human. (rutgers.edu)
  • I would not trust any doctor who claims that he/she has a stem cell therapy that does so and charge you for the therapy. (rutgers.edu)
  • Of course we'd love the magic stem cell or other treatment if it even gave him a hint of some movement back but so be it. (rutgers.edu)
  • Dr. Spetzler at the Barrow Institute wanted to go in on the left lateral approach, but we could not get the insurance to approve it.I want to know if there are any stem cell trials available out there for the brain. (rutgers.edu)
  • He is known to have introduced microdialysis of brain and stem cell therapy for cerebral palsy for the first time in Asia. (wikipedia.org)
  • They send these signals by means of an axon, which is a thin protoplasmic fiber that extends from the cell body and projects, usually with numerous branches, to other areas, sometimes nearby, sometimes in distant parts of the brain or body. (wikipedia.org)
  • Cell replacement therapy Cerebral organoids can be used as a simple model to show how cell replacement therapy would work on brain tissues. (wikipedia.org)
  • Cell-type specific genome assays Organoids can be used to study the crucial early stages of brain development, test drugs and, because they can be made from living cells, study individual patients. (wikipedia.org)
  • However, another in vivo study, using NSCs in the postnatal SVZ, showed that the stem cell is restricted to developing into different neuronal sub-type cells in the olfactory bulb. (wikipedia.org)
  • It is believed that the various spatial location niches regulate the differentiation of the neural stem cell. (wikipedia.org)
  • There has been limited but encouraging success with stem-cell treatment. (wikipedia.org)
  • In January 2017, Wyatt travelled to Mexico for pioneering treatment of her illness, involving a stem-cell transplant. (wikipedia.org)
  • In their neurological origins and near-limitless ability to create new cells, glioblastoma stem cells reminded postdoctoral researcher Zhe Zhu, PhD, of neuroprogenitor cells, which generate cells for the growing brain. (newswise.com)
  • Brain death implies the complete and permanent absence of neurological function in the cortex and the brainstem . (dictionary.com)
  • c diVuse or extensive processes aVecting the whole brain c supratentorial mass lesions causing tentorial herniation with brain stem compression (associated with other neurological signs such as third nerve palsy and crossed hemiparesis) c brain stem lesions-for example, compression from posterior fossa mass lesions such as cerebellar haemorrhage/infarction and disorders primarily aVecting the brain stem (for example, basilar artery thrombosis). (scribd.com)
  • Curcumin is also capable of crossing the blood-brain barrier, which is one reason why it holds promise as a neuroprotective agent in a wide range of neurological disorders. (mercola.com)
  • Neurological disorders such as multiple sclerosis, epilepsy, Alzheimer's disease, and Huntington's disease, which collectively affect millions worldwide, have been linked to a defective blood-brain barrier. (mddionline.com)
  • Significantly, when this blood-brain barrier was derived from cells of patients with Allan-Herndon-Dudley syndrome, a rare congenital neurological disorder, and Huntington's disease patients, the barrier malfunctioned in the same way that it does in patients with these diseases. (mddionline.com)
  • Elsewhere in the world the concept upon which the certification of death on neurological grounds is based is that of permanent cessation of all function in all parts of the brain-whole brain death-with which the reductionist United Kingdom concept should not be confused. (wikipedia.org)
  • In particular, there must be definite clinical or neuro-imaging evidence of acute brain pathology (e.g. traumatic brain injury, intracranial haemorrhage, hypoxic encephalopathy) consistent with the irreversible loss of neurological function. (wikipedia.org)
  • The following diseases manifest by means of neurological dysfunction: Lambert-Eaton myasthenic syndrome, paraneoplastic cerebellar degeneration, encephalomyelitis, limbic encephalitis, brainstem encephalitis, opsoclonus myoclonus ataxia syndrome, anti-NMDA receptor encephalitis, and polymyositis. (wikipedia.org)
  • N. K. Venkataramana is an Indian neurosurgeon and the founder of ANSA Research Foundation, a non profit non governmental organization promoting research on neuroscience, neurological disorders, cancer biology, stem cells and tumor tissue repository. (wikipedia.org)
  • Holmkvist, "Bilaterally recorded auditory brainstem responses to monaural stimulation. (thefreedictionary.com)
  • In an exclusive interview with Gulf News, the doctors from the ENT (ears, nose and throat) department at Dubai Hospital said they carried out an auditory brainstem implant (ABI) procedure in the first week of July. (thefreedictionary.com)
  • These include electrically evoked auditory brainstem response (EABR), electrically evoked stapedial reflex threshold (ESRT), electrically compound action potentials (ECAP), middle latency responses (MLR), and cortical responses (CR). (thefreedictionary.com)
  • The auditory brainstem response (ABR) was measured 48 h prior to the placement of a CSF shunt and within 5 days following shunt insertion. (springer.com)
  • Despland P, Galambos R (1980) The auditory brainstem response (ABR) as a useful diagnostic tool in the intensive care nursery. (springer.com)
  • Hecox K, Cone B, Blaw M (1981) Brainstem auditory evoked response in the diagnosis of pediatric neurologic diseases. (springer.com)
  • Kevanihvili Z (1981) Considerations of the source of the human brainstem auditory evoked potential on the basis of bilateral asymmetry of its parameters. (springer.com)
  • McPherson D, Hirasugi Y, Starr A (1984) Auditory brainstem potentials recorded at different scalp locations in neonates and adults. (springer.com)
  • McPherson D, Waffarn F, Glatz T, Huxtable R (1982) Alterations in the auditory brainstem evoked potentials in preterm infants with ventriculomegaly. (springer.com)
  • Correlated brain stem and cortical evoked responses to auditory tone change. (nih.gov)
  • Numerous human studies have separately observed the effects of auditory stimuli at brain stem and cortical levels, but little research has focused on possible functional coupling between these diverse brain areas. (nih.gov)
  • These results suggest that signal processing reflected in long-latency auditory evoked response components is not exclusively a cortical phenomenon, but also depends upon patterns of neural processing occurring in brain stem pathways. (nih.gov)
  • The auditory evoked brainstem responses of guinea pigs in two age groups were recorded and examined for evidence of age-dependent changes at peripheral stations in the auditory pathway. (springer.com)
  • Achor LJ, Starr A (1980) Auditory brain stem responses in the cat. (springer.com)
  • Hecox K, Galambos R (1974) Brainstem auditory evoked responses in human infants and adults. (springer.com)
  • An auditory brainstem implant (ABI) is a surgically implanted electronic device that provides a sense of sound to a person who is profoundly deaf, due to retrocochlear hearing impairment (due to illness or injury damaging the cochlea or auditory nerve, and so precluding the use of a cochlear implant). (wikipedia.org)
  • The auditory brainstem implant uses technology similar to that of the cochlear implant, but instead of electrical stimulation being used to stimulate the cochlea, it is used to stimulate the brainstem of the recipient. (wikipedia.org)
  • Only about one thousand five hundred recipients have been implanted with an auditory brainstem implant, due to the nature of the surgery required to implant the device (as it requires brain surgery to implant the device). (wikipedia.org)
  • In January 2013, the US FDA approved a clinical trial of auditory brainstem implants for children. (wikipedia.org)
  • The auditory brainstem electrodes were first implanted in humans in 1979 at the House Ear Institute, CA, USA. (wikipedia.org)
  • Brain implant "FDA Approves Clinical Trial of Auditory Brainstem Implant Procedure for Children in U.S". ScienceDaily. (wikipedia.org)
  • The auditory brainstem response (ABR) is an auditory evoked potential extracted from ongoing electrical activity in the brain and recorded via electrodes placed on the scalp. (wikipedia.org)
  • The ABR is used for newborn hearing screening, auditory threshold estimation, intraoperative monitoring, determining hearing loss type and degree, and auditory nerve and brainstem lesion detection, and in development of cochlear implants. (wikipedia.org)
  • In human neuroanatomy, brainstem auditory evoked potentials (BAEPs), also called brainstem auditory evoked responses (BAERs), are very small auditory evoked potentials in response to an auditory stimulus, which are recorded by electrodes placed on the scalp. (wikipedia.org)
  • They reflect neuronal activity in the auditory nerve, cochlear nucleus, superior olive, and inferior colliculus of the brainstem. (wikipedia.org)
  • Bone-conduction auditory brainstem response or BCABR is a type of auditory evoked response that records neural response from EEG with stimulus transmitted through bone conduction. (wikipedia.org)
  • Bone-conduction auditory brainstem response (BCABR) are similar to air conduction auditory brainstem responses, with the main difference being that the signal is transmitted via bone-conduction instead of air. (wikipedia.org)
  • Techniques and results for bone-conduction auditory brainstem responses are presented in a review chapter by Stapells, as well as in a detailed assessment protocol by the British Columbia Early Hearing Program (BCEHP). (wikipedia.org)
  • With Bone ABR, the waves are typically more rounded that with traditional auditory brainstem response. (wikipedia.org)
  • It is the main auditory tract in the brainstem that connects the superior olivary complex (SOC) with the inferior colliculus (IC). (wikipedia.org)
  • The most common clinical applications of electrocochleography include: Objective identification and monitoring of Ménière's disease and endolymphatic hydrops (EH) Intraoperative monitoring of auditory system function during surgery on the brainstem or cerebellum Enhancement of Wave I of the auditory brainstem response, particularly in patients who are hard of hearing Diagnosis of auditory neuropathy The basilar membrane and the hair cells of the cochlea function as a sharply tuned frequency analyzer. (wikipedia.org)
  • When a certain threshold potential is reached, the spiral ganglion neuron fires an action potential, which enters the auditory processing pathway of the brain. (wikipedia.org)
  • The first and largest wave (N1) is identical to wave I of auditory brainstem response (ABR). (wikipedia.org)
  • Part of the auditory brainstem response (ABR), the FFR reflects sustained neural activity integrated over a population of neural elements: "the brainstem response. (wikipedia.org)
  • The term "lazy ear" has been used to describe amblyaudia although it is currently not known whether it stems from deficits in the auditory periphery (middle ear or cochlea) or from other parts of the auditory system in the brain, or both. (wikipedia.org)
  • this is evident by measuring the auditory brainstem response using EEG. (wikipedia.org)
  • He has many firsts to his credit such as the performance of the first auditory brain stem implantation surgery in South and South East Asia, the first pediatric brain stem implantation surgery in Asia, the first totally implantable hearing device surgery in Asia Pacific region, and the first to introduce KTP/532 laser-assisted ENT surgery in India. (wikipedia.org)
  • In 2005, Kameswaran performed the first auditory brainstem implant surgery in South Asia and five years later, he performed the surgery on a child, becoming the first in Asia to perform the pediatric auditory brainstem implant. (wikipedia.org)
  • Laquinimod is a monoclonal antibody in phase III trials for treatment of MS. Unlike other disease-modifying MS therapies, a portion of the drug, about 10%, crosses into the brain. (medpagetoday.com)
  • Being able to maintain viable stem cells in the brain could lead to regenerative therapies to treat injury and disease," says Jing Crystal Zhao, Ph.D., assistant professor at SBP. (eurekalert.org)
  • Patients with hypoxic/ischemic brain injury, with an between 1 month and 18 years, regardless the age at the time of injury, time post-injury, or previously received therapies, different from ours. (clinicaltrials.gov)
  • In theory, if the cancer stem cells can be destroyed, a tumor may not be able to sustain itself, but if the cancer originators are not removed or destroyed, a tumor will continue to return despite the use of existing cancer-killing therapies. (eurekalert.org)
  • HOUSTON - A tailored virus destroys brain tumor stem cells that resist other therapies and cause lethal re-growth of cancer after surgery, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in the Sept. 18 edition of the Journal of the National Cancer Institute. (eurekalert.org)
  • Additionally, the medulla oblongata serves as a relay system, and it plays a large part in carrying nerve impulses to and from the brain. (reference.com)
  • The medial lemniscus, also known as Reil's band or Reil's ribbon, is a large ascending bundle of heavily myelinated axons that decussate in the brainstem, specifically in the medulla oblongata. (wikipedia.org)
  • ends at the gracile nucleus in medulla oblongata of the brainstem. (wikipedia.org)
  • In anatomy, the olivary bodies or simply olives (Latin oliva and olivae, singular and plural, respectively) are a pair of prominent oval structures in the medulla oblongata, the lower portion of the brainstem. (wikipedia.org)
  • This approach "represents a promising new treatment for malignant brain tumours," the authors write in the journal Cancer Research . (newscientist.com)
  • UCSF scientists have discovered that a tiny filament extending from cells, until recently regarded as a remnant of evolution, may play a role in the most common malignant brain tumor in children. (medindia.net)
  • We don't know yet if the response would be strong enough to prevent a tumor from coming back, but we now have a human clinical trial underway to assess safety for further study," said John Yu, MD, vice chair of the Department of Neurosurgery, director of surgical neuro-oncology, medical director of the Brain Tumor Center and neurosurgical director of the Gamma Knife Program at Cedars-Sinai. (eurekalert.org)
  • Dr Robert Iacono tried this, with fetal stem cells, back in 1989, and since he couldn't find a hospital in the US that would permit it, he dragged his patient, one Max Truex, to a clinic in Zhengzhou, China, where he had no problem in 'acquiring' fetal cells. (freerepublic.com)
  • Future studies of these cells are expected to shed light on developmental diseases such as autism and schizophrenia and malformations of brain development, including microcephaly, lissencephaly and neuronal migration disorders, they say, as well as age-related illnesses, such as Alzheimer's disease. (redorbit.com)
  • Diseases of the brainstem can result to abnormalities in the function of cranial nerves which may lead to visual disturbances, pupil abnormalities, changes in sensation, muscle weakness, hearing problems, vertigo, swallowing and speech difficulty, voice change, and co-ordination problems. (patientslikeme.com)
  • This gives us hope that stem cells someday could help restore brain function in humans suffering from a wide range of diseases and injuries that impair memory formation," LaFerla said. (thaindian.com)
  • This complexity has made studying the brain and understanding how it works a difficult task in neuroscience, especially when it comes to neurodegenerative diseases. (wikipedia.org)
  • The largest reservoir is the subventricular zone, where quiescent stem cells lie closely packed together. (eurekalert.org)
  • We believe there may be similar quiescent stem cells in other organs, and this discovery could help improve or develop new regenerative medicines,' he adds. (news-medical.net)
  • Recurrent focal brain stem gliomas may be treated with surgery, radiation therapy or chemotherapy or a combination of these treatments. (cancer.ca)
  • New research from Washington University School of Medicine in St. Louis and the University of California San Diego School of Medicine shows that the virus kills brain cancer stem cells, the kind of cells most resistant to standard treatments. (newswise.com)
  • Stephen G. Emerson, MD, PhD, director of the Herbert Irving Comprehensive Cancer Center at NewYork-Presbyterian Hospital/Columbia University Medical Center, added that, "Understanding the pathway that allows stem cells to develop into mature cells could eventually lead to more effective, less toxic cancer treatments. (eurekalert.org)
  • Dr. Boockvar believes that these patients' drug resistance might be due to a class of stem cells resistant to available treatments. (news-medical.net)
  • Ultimately the goal is to strengthen these mechanisms anddevelop new treatments that can repair the diseased brain. (medindia.net)