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  • tumors
  • Brain edema continues to be a major cause of mortality after diverse types of brain pathologies such as major cerebral infarcts, hemorrhages, trauma, infections and tumors. (springer.com)
  • XERECEPT is not a potential treatment for cancer, but may reduce the edema associated with tumors and as a result, decrease neurological symptoms. (knowcancer.com)
  • Injury, other health problems, infections, tumors, and even high altitudes -- any of these problems can cause brain swelling to occur. (webmd.com)
  • Tumors in some parts of the brain may block cerebrospinal fluid from flowing out of the brain. (webmd.com)
  • The clinical application of IL-2 and IFN-γ gene transfer therapy for intracerebral tumors must consider the potential for severe vasogenic brain edema associated with intracerebral production of these cytokines. (aacrjournals.org)
  • Baseline
  • If a patient is on dexamethasone for treatment of symptomatic peritumoral brain edema, the dose must be stable and should not exceed 24mg/dl for a minimum of 7 days prior to Baseline. (knowcancer.com)
  • Presence of peritumoral brain edema confirmed by MRI scan or comparable diagnostic technology obtained within 21 days of Baseline. (knowcancer.com)
  • The purpose of this work is to investigate whether elevation of these proteins at baseline predicts CT-evidence of brain edema. (medsci.org)
  • Both NT-PBNP and PC levels correlated poorly to NIHSS score and increased markedly from baseline to the second determination in patients with edema. (medsci.org)
  • The main goal of this work is to find accurate baseline markers of delayed brain edema that might be helpful to anticipate the appropriate and early anti-edema measures. (medsci.org)
  • Swelling
  • While in other organs swelling does not lead to an urgent situation, in the brain it leads to coma and death. (isciencetimes.com)
  • Swelling -- also called edema -- is the body's response to many types of injury. (webmd.com)
  • Brain swelling , though, can quickly cause serious problems -- including death. (webmd.com)
  • What Is Brain Swelling? (webmd.com)
  • Swelling can occur in specific locations or throughout the brain. (webmd.com)
  • Wherever it occurs, brain swelling increases pressure inside the skull. (webmd.com)
  • Swelling can also block other fluids from leaving your brain, making the swelling even worse. (webmd.com)
  • What Causes Brain Swelling? (webmd.com)
  • Too much swelling may prevent fluids from leaving the brain. (webmd.com)
  • As the brain responds, swelling can occur. (webmd.com)
  • Illness caused by an infectious organism such as a virus or bacterium can lead to brain swelling. (webmd.com)
  • Growths in the brain can cause swelling in several ways. (webmd.com)
  • The present invention relates generally to a method and system for detecting swelling occurring as a result of increased water content in and around the brain. (google.com)
  • With increasing ICP from brain swelling or an expanding mass lesion, brain stem compression and subsequent RAS compression can occur. (cancerstreatment.com)
  • severe
  • Edema of the ankles and lower legs (in ambulatory patients) is characteristic of congestive heart failure, but it can accompany other conditions, including obesity, diseased leg veins, kidney disease, cirrhosis of the liver, anemia, and severe malnutrition. (thefreedictionary.com)
  • High levels of mortality and morbidity are attributed to severe brain edema after primary injury [ 1 , 2 , 3 , 4 ]. (alliedacademies.org)
  • pathogenesis
  • Basic information about the types of edema is provided for better understanding of the expression pattern of some of the newer molecules implicated in the pathogenesis of brain edema. (springer.com)
  • Since many molecules are involved in the pathogenesis of brain edema, effective treatment cannot be achieved by a single agent but will require the administration of a "magic bullet" containing a variety of agents released at different times during the course of edema in order to be successful. (springer.com)
  • Our findings point to a significant role of MMP-9 and VEGF in the pathogenesis of peritumoral brain edema in low- and high-grade meningiomas. (hindawi.com)
  • Membrane water transport is critically involved in brain volume homeostasis and in the pathogenesis of brain edema. (semanticscholar.org)
  • glial
  • Specialized membrane domains for water transport in glial cells: high-resolution immunogold cytochemistry of aquaporin-4 in rat brain. (semanticscholar.org)
  • Blood-brain barrier (BBB) breakdown to Evans blue albumin (EBA 3 ml/kg, i.v.) and -Iodine (100 µCi/kg, i.v.) was examined 24 h after AuNPs administration in the brain in relation to edema formation and neuronal or glial injuries using standard procedures. (techconnect.org)
  • abnormal
  • The resulting collection of water within the skull is a serious and usually incurable condition (see hydrocephalus hydrocephalus , also known as water on the brain, developmental (congenital) or acquired condition in which there is an abnormal accumulation of body fluids within the skull. (thefreedictionary.com)
  • clinical
  • however some limited data suggest that the expression of matrix metalloproteinases (MMPs) and vascular endothelial growth factor (VEGF) may be associated with the presence of peritumoral brain edema (PTBE) and worse clinical outcome. (hindawi.com)
  • empyema
  • Subdural empyema refers to an area of the brain becoming abscessed or filled with pus, usually after another illness such as meningitis or a sinus infection . (webmd.com)
  • ventricular
  • Brain natriuretic peptide (BNP) is released from the ventricular myocardium in response to elevation of ventricular diastolic pressure [ 1 ]. (medsci.org)
  • natriuretic peptide
  • Brain uptake of [14C]sucrose was measured 30 minutes after lesions were induced by 0.4 IU collagenase alone (n = 5) or after collagenase injection and 50 micrograms/kg per hour (n = 5) atrial natriuretic peptide injected intravenously. (ahajournals.org)
  • cirrhosis
  • Edema-chiefly hypoproteinemic-in the late stages of cirrhosis of the liver is usually combined with ascites and found mainly in the legs, lumbar region, and anterior abdominal wall. (thefreedictionary.com)
  • relation
  • Thus, it would be interesting to examine AuNPs neurotoxicity in vivo models in relation to size related effects on brain pathology. (techconnect.org)