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  • differentiation
  • The rodent retina undergoes considerable postnatal neurogenesis and phenotypic differentiation, and it is likely that diffusible neurotrophic factors contribute to this development and to the subsequent formation of functional retinal circuitry. (uniprot.org)
  • Humans
  • Neurological research on humans is hampered by the fact that experimentation on the brain is deemed unethical, forcing researchers to rely on observation and retrospective evaluation to collect data on the role of various compounds in the human brain. (wisegeek.com)
  • trophic
  • One type is primarily trophic and involves long-distance transport of target-derived signals from distal terminals to the nucleus. (jneurosci.org)
  • tissue
  • Fetal hippocampi were dissected from surrounding brain tissue, and meninges were completely removed. (jneurosci.org)
  • This is the case for various adhesion molecules ( 15 , 16 ), including NCAM ( 7 ), for tissue plasminogen activator ( 17 ), an extracellular protease involved in many aspects of morphogenesis, and for growth factors ( 18 , 19 ). (pnas.org)