• We then conducted a meta-analysis of structural MRI studies to identify brain regions that are abnormal in BD. (nih.gov)
  • Brain regions with the highest and lowest expression of these genes did not overlap strongly with anatomical sites identified as abnormal by structural MRI except in the parahippocampal gyrus, the inferior/superior temporal gyrus and the cerebellar vermis, regions where overlap was significant. (nih.gov)
  • The other main subject headings on the home page let you explore numerous images of abnormal brains, such as the brains of people who have had strokes or have brain tumours or various degenerative, inflammatory or infectious brain diseases. (blog-thebrain.org)
  • This 2D vector-based atlas contains coronal, sagittal, and horizontal brain sections of an athymic rat brain rendered from a single cleared specimen, placed in a computerized 3D environment. (lu.se)
  • Here alone, you can have hours of fun clicking on the little black-on-yellow directional arrows to explore successive slices of the brain in the transaxial, sagittal and coronal planes. (blog-thebrain.org)
  • You must click the Start button to the lower right to choose which of the axial, coronal or sagittal sections you want to explore, and then choose between two major regions of the brain. (blog-thebrain.org)
  • Auditory researchers stand to benefit from a three dimensional brain atlas of this species, due to its considerable contribution to auditory neuroscience. (omeka.net)
  • Please, rest assured that we are doing our utmost to continue our mission of providing the general public with the best possible information about the brain and neuroscience in the original spirit of the Internet: the desire to share information free of charge and with no adverstising. (blog-thebrain.org)
  • Our results highlight the complex neuroanatomical basis of BD, and reinforce illness models that emphasize impaired brain connectivity. (nih.gov)
  • M/EEG brain connectivity is an important and exciting topic. (besa.de)
  • On the home page, under the heading Normal Brain, the first topic is Normal Anatomy in 3-D with MRI/PET (Javascript) . (blog-thebrain.org)
  • are designed to let you have fun while learning brain anatomy. (blog-thebrain.org)
  • These researchers sliced, scanned, and analyzed the brain of a deceased 65-year-old woman to create a detailed 3D computer model of an entire human brain. (blog-thebrain.org)
  • Studies of bipolar disorder (BD) suggest a genetic basis of the illness that alters brain function and morphology. (nih.gov)
  • Using an anatomically comprehensive survey of the human transcriptome (The Allen Brain Atlas), we mapped the expression of 58 genes with suspected involvement in BD based upon their relationship to SNPs identified in genome wide association studies (GWAS). (nih.gov)
  • This atlas is freely available from our website and can simplify future electrophysiological, microinjection, and neuroimaging studies in this and related species. (omeka.net)
  • Athymic Nude Rat Brain Atlas will provide the first stereotaxic brain atlas of the athymic nude rat (Crl:NIH-Foxn1rnu), a T-cell deficient rat model commonly used in experimental studies and pre-clinical safety and efficacy studies. (lu.se)
  • This atlas will be a valuable resource for any neuroscientist who wishes to work with nude rats in experimental and pre-clinical studies. (lu.se)
  • This study examined a cohort of mixed-sex mesaticephalic canines and used diffusion tensor imaging (DTI), an MRI technique, to map connections from the olfactory bulb to other cortical regions of the brain. (jneurosci.org)
  • This week I want to tell you about three different on-line atlases of the human brain. (blog-thebrain.org)
  • The third and last atlas that I want to mention is the Big Brain , published in June 2013 , It is part of the Human Brain Project and was produced by an international team of neuroscientists from the Montreal Neurological Institute in Canada and the Forschungszentrum Jülich in Germany. (blog-thebrain.org)
  • This webinar will explore some of the underlying concepts, and show the use of beamforming in source imaging, and also as a tool to provide virtual sensors inside the brain for exploring raw data. (besa.de)
  • We discovered an extensive white matter network extending from the olfactory bulb to form novel connections directly to other cortices of the brain. (jneurosci.org)
  • The page How To Use the Interactive Interface explains the symbols and abbreviations used in this atlas and the various planes of the brain sections shown in it. (blog-thebrain.org)
  • Thus, unlike the two other atlases, which consist of images of sections of living people's brains, captured by magnetic resonance imaging (MRI) , this one consists of coloured sections of a person's brain post mortem . (blog-thebrain.org)
  • The BESA Webinars enable you to learn about topics directly related to your work, conveniently from your work place - no travel required! (besa.de)
  • Despite this evidence that olfaction plays a key role in canine cognition and behavior, the structure of the dog olfactory system within the brain remains a mystery. (jneurosci.org)
  • Our MRI-based atlas was generated from 2 sets of image data of an ex-vivo male mustached bat's brain: a detailed 3D-T2-weighted-RARE scan [(59x63 x 85) mum(3)] and track density images based on super resolution diffusion tensor images [(78) mum(3)] reconstructed from a set of low resolution diffusion weighted images using Super-Resolution-Reconstruction (SRR). (omeka.net)
  • After providing all the funding for The Brain from Top to Bottom for over 10 years , the CIHR Institute of Neurosciences, Mental Health and Addiction informed us that because of budget cuts, they were going to be forced to stop sponsoring us as of March 31st, 2013. (blog-thebrain.org)
  • The scientists combined the gene activity data with the neuroimaging data and anatomical reference atlases. (nih.gov)
  • An example plate from 1 of the BrainSpan Reference Atlases (21 weeks after conception). (medscape.com)
  • The overarching BRAIN Initiative Cell Atlasing Program goal is to build reference brain cell atlases that will be widely used throughout the research community, providing a molecular and anatomical foundational framework for the study of brain function and disease. (nih.gov)
  • We present a new automated segmentation method specifically designed to achieve a consistent parcellation of anatomical brain structures in such heterogeneous datasets. (nih.gov)
  • Our method combines a site-specific atlas creation strategy with a state-of-the-art multi-atlas anatomical label fusion framework. (nih.gov)
  • 100 million cells) has been generated to date from human and other mammalian brains by the National Institutes of Health's (NIH) Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative - Cell Census Network (BICCN) and the Cell Atlas Network (BICAN) and the broad research community to characterize brain cell types and states across lifespan and diseases. (nih.gov)
  • For example, the human Brainnetome atlas was developed based on the connectional architecture, which not only contains fine-grained structures of both cortical and subcortical regions but also provides a quantitative mapping of the anatomy and functional connectivity patterns. (bnu.edu.cn)
  • Comparative white matter atlases provide a useful tool for identifying neuroanatomical differences and similarities between humans and other primate species. (ox.ac.uk)
  • Until now, comprehensive fascicular atlases have been created for humans (Homo sapiens), rhesus macaques (Macaca mulatta), and several other nonhuman primate species, but never in a nonhuman ape. (ox.ac.uk)
  • Therefore, comparative studies among primate species will help to further clarify the similarities and differences in the structure and function of the brain between non-human primates and humans. (bnu.edu.cn)
  • The work was funded by NIH's National Institute of Mental Health (NIMH) and Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) as part of the BrainSpan Atlas of the Developing Human Brain. (nih.gov)
  • Although the many genes associated with autism and schizophrenia don't show a clear relationship to each other in the adult brain, the BrainSpan Atlas reveals how these diverse genes are connected in the developing brain," says NIMH Director Dr. Thomas R. Insel. (nih.gov)
  • The comprehensive, anatomically correct, and very-high-resolution BrainSpan Atlas of the Developing Human Brain demonstrates gene expression in the midgestational brain. (medscape.com)
  • The BrainSpan Atlas aims to inspire new hypotheses regarding human brain development and has already led to some surprising findings. (medscape.com)
  • Shed new insights on brain cell functional studies by using cell atlasing data and cell type-specific targeting tools. (nih.gov)
  • This Program Announcement (PA), "MOUSE BRAIN ATLAS FOR FUNCTIONAL GENOMICS", is related to various priority area relevant to each sponsoring institute, including Mental Health and Mental Disorders, Alcohol and Other Drugs/Substance Abuse, Heart Disease and Stroke, Cancer, and Maternal and Infant Health. (nih.gov)
  • In recent years, on one hand, it is possible to non-invasively delineate the structural and functional areas of the human brain and map its connectivity patterns using multimodal brain imaging, which provides a new approach to the development of the next-generation of human brain atlases. (bnu.edu.cn)
  • What has become quite clear from our atlases - and we have atlases in the adult mouse, the developing mouse, the adult human, and now the developing human - is that when you compare the patterns between species, there are many differences," said Dr. Lein. (medscape.com)
  • Auditory researchers stand to benefit from a three dimensional brain atlas of this species, due to its considerable contribution to auditory neuroscience. (omeka.net)
  • This atlas is freely available from our website and can simplify future electrophysiological, microinjection, and neuroimaging studies in this and related species. (omeka.net)
  • At present, mapping of the non-human primate brains is incomplete and relatively preliminary, which has limited our understanding of brain structure and function. (bnu.edu.cn)
  • Here we offer, in comparative perspective, the first chimpanzee white matter atlas, constructed from in vivo chimpanzee diffusion-weighted scans. (ox.ac.uk)
  • These papers coincide with the first anniversary of President Obama's Brain Initiative. (medscape.com)
  • As longitudinal and multi-site studies become increasingly frequent in neuroimaging, maintaining longitudinal and inter-scanner consistency of brain parcellation has become a major challenge due to variation in scanner models and/or image acquisition protocols across scanners and sites. (nih.gov)
  • Multi-atlas parcellation (MAP) is carried out on a brain image by propagating and fusing labelled regions from brain atlases. (korea.ac.kr)
  • However, most existing DLP methods neglect using brain atlases, which contain high-level information (e.g., manually labelled brain regions), to provide auxiliary features for improving the parcellation accuracy. (korea.ac.kr)
  • In this paper, we propose a novel multi-atlas DLP method for brain parcellation. (korea.ac.kr)
  • It can automatically and adaptively select features from the most relevant brain atlases to guide parcellation. (korea.ac.kr)
  • The structure and function of the human brain is guided by gene expression patterns during prenatal development. (nih.gov)
  • Scientists released the first comprehensive 3-D atlas of gene expression in the developing human brain. (nih.gov)
  • The structure and function of the brain have long been the topic of exploration by scientists. (bnu.edu.cn)
  • An anatomically precise molecular atlas of the brain during this time period is a first step to understanding how the human brain develops normally and what can go wrong. (nih.gov)
  • Many neuropsychiatric diseases are likely the result of abnormal brain development during prenatal life. (nih.gov)
  • In research on brain-based diseases, one must understand the basic biology in order to learn what normal processes may be disrupted. (medscape.com)
  • It is not only important to understand the unique cognitive functions of the human brain, but also essential for the establishment of non-human primate models of major brain diseases and the development of new techniques for diagnosis and therapy. (bnu.edu.cn)
  • The first symposium, "Utilizing Single Cell Technologies to Understand Brain Development," will be hosted by Dr. Timothy Petros on May 12, 2022 via Zoom, https://nih.zoomgov.com/j/1603982143 . (nih.gov)
  • This atlas will likely comprise an array of interoperating informatics tools and approaches for handling gene expression data obtained from the mouse nervous system. (nih.gov)
  • The intention is to introduce early versions of these tools to the research community generating gene expression data and to develop an atlas of the nervous system of the C57BL6/J strain of mouse. (nih.gov)
  • This project aims to profile gene expression throughout the course of brain development. (nih.gov)
  • Custom microarrays revealed gene expression levels in laser-microdissected brain regions. (nih.gov)
  • However, our understanding of the transcriptome-when and where genes are turned on-in the developing brain has been limited. (nih.gov)
  • the simplest way to do it is to write manually the atlas you need either into a txt or xls file, or directly into Braph. (braph.org)
  • Ultra-high resolution MRI and diffusion tensor imaging provided structural information about the brains. (nih.gov)
  • But the human brain has many unique qualities. (nih.gov)
  • Transcriptional landscape of the prenatal human brain. (nih.gov)
  • Cite this: Atlas of Human Brain Development Released - Medscape - Apr 11, 2014. (medscape.com)
  • Animal studies have provided insights in the basic mechanisms of brain function. (nih.gov)
  • We tried to take a deep, detailed look at this critical period of cortical development," lead author Ed Lein, PhD, an investigator at the Allen Institute for Brain Science in Seattle, Washington, told Medscape Medical News . (medscape.com)
  • Develop strategies with brain disease research communities to maximally leverage BICCN/BICAN data. (nih.gov)
  • In recognition of these needs, this Program Announcement (PA) solicits grant applications to research and develop a digital multidimensional atlas that ultimately will serve as a platform to organize and integrate genomic data obtained from the mouse nervous system. (nih.gov)
  • It is not expected that any one research group would develop all of the tools needed or atlases of all parts of the nervous system. (nih.gov)
  • A three-dimensional digital neurological atlas of the mustached bat (Pteronotus parnellii). (omeka.net)
  • The resource will help reveal the early roots of brain-based disorders such as autism and schizophrenia. (nih.gov)
  • Findings of what goes on early in the prenatal brain can lead to the development of biomarkers for diagnosing brain disorders and for matching patients to treatment options most likely to be successful. (nih.gov)
  • A comprehensive atlas of white matter tracts in the chimpanzee. (ox.ac.uk)
  • Atlases, informatics tools, and other materials and information generated in projects funded under this PA will be made widely available to the scientific community. (nih.gov)
  • Most of our atlases are in fact .iso or .img files and we are struggling to find conversion tools online. (braph.org)
  • Benefiting from brain atlases, our method outperforms MAP and state-of-the-art DLP methods on two public image datasets (LPBA40 and NIREP-NA0). (korea.ac.kr)
  • Using quantitative meta-analyses of fMRI studies we identified brain regions concordant among studies that used number and calculation tasks. (nih.gov)
  • Nonstop Metropolis, the culminating volume in a trilogy of atlases, conveys innumerable unbound experiences of New York City through twenty-six imaginative maps and informative essays. (barnesandnoble.com)