• Mar. 1, 2023 Some areas of the adult brain contain quiescent, or dormant, neural stem cells that can potentially be reactivated to form new neurons. (sciencedaily.com)
  • With around 80 billion neurons and 100 trillion connections in the brain, it has been challenging for neuroscientists to untangle the networks that give rise to behavior. (neurosciencenews.com)
  • Measuring changes in the activity of neurons in a cortical area while perturbing the activity in another area. (neurosciencenews.com)
  • The neuroscientists recorded from populations of neurons in V1 and LM in mice and used optogenetics to briefly silence the activity of one area and quantify how the activity increased or decreased in the other area. (neurosciencenews.com)
  • Neurons (nerve cells) are labeled with green fluorescent protein, and other neurons in the brain are labeled in the background with either red or blue tracers. (scitechdaily.com)
  • Although other studies had looked at the effects of deafening on neurons in auditory brain areas, this is the first time that scientists have been able to watch how deafening affects connections between nerve cells in a vocal motor area of the brain in a living animal, said Katie Tschida, PhD, a postdoctoral research associate in the Mooney laboratory who led the study. (scitechdaily.com)
  • According to a new study, norepinephrine-producing neurons in this brain region control the areas of the prefrontal cortex that allow us to focus, ignore distractions or curb impulses. (zmescience.com)
  • Work in this area creates a window into how neurons are born and migrate, and how they form synaptic connections. (mit.edu)
  • Studying the ways that neurons operate will move us closer to understanding how the brain develops and responds to outside stimuli. (mit.edu)
  • This provides strong motivation to define how these molecular and cellular pathways allow neurons to connect and communicate, and how they go awry in brain diseases. (mit.edu)
  • We systematically compared the ability of AAV1, AAV2, AAV5, AAV8, AAV9, and AAVrg to enter four specific brain regions and transduce two main cell types: neurons and astrocytes. (au.dk)
  • These modifications, observed in mice, may alter the activity of a variety of neurons and nerve signaling proteins in response to stress, and could be related to stress' effects on the brain in anxiety and traumatic stress disorders. (bbrfoundation.org)
  • The relationship seems relatively straightforward: the process of learning to type faster or play a violin causes the neurons in the relevant area of the cortex to make new connections, which causes the cortex to appear thicker. (bioquicknews.com)
  • Robert - Essentially what opto-genetics is, is a technology that allows scientists to control the activity of neurons, the cells that mediate transmission in the brain using light. (thenakedscientists.com)
  • neurons) in certain areas of the brain. (medlineplus.gov)
  • May 25, 2023 Regular walks strengthen connections in and between brain networks, according to new research, adding to growing evidence linking exercise with slowing the onset of Alzheimer's disease. (sciencedaily.com)
  • Mayo Clinic Minute: Learn about meningioma and glioblastoma brain tumors Aug. 07, 2023, 02:00 p.m. (mayoclinic.org)
  • Two specialized areas of the brain are responsible for certain auditory functions, a team of Georgetown researchers led by Josef P. Rauschecker, PhD, professor of physiology and biophysics, has found. (sciencedaily.com)
  • This technology allows researchers to observe brain activity in response to certain types of speech sounds and music. (sciencedaily.com)
  • To be sure that the effect was real, the researchers also pretended to stimulate the lateral OFC in the same patients without actually running current through the tiny wires implanted in their brains. (kpbs.org)
  • In a previous, related study , UCSF researchers had used a different group of epilepsy patients to identify circuits in the brain that indicated whether people were happy or sad. (kpbs.org)
  • Researchers at Washington University School of Medicine in St. Louis have identified specific areas and cells in the brain that become active when an individual is faced with the choice to learn or hide from information about an unwanted aversive event the individual likely has no power to prevent. (labmanager.com)
  • In a proof-of-principle study, the researchers showed that pharmacologically active amounts of a fast-acting drug could be released from these cages in small areas of the rats' brains targeted by a beam of focused ultrasound. (stanford.edu)
  • By turning up the ultrasound intensity and monitoring brainwide metabolic activity, the researchers could also observe the drug's secondary effects on distant downstream brain regions receiving input from the targeted area, said Raag Airan , MD, PhD, an assistant professor of neuroradiology. (stanford.edu)
  • In this way, the researchers were able to noninvasively map out the connections among disparate circuits in the living brain. (stanford.edu)
  • Researchers identified how the primary visual cortex and the lateromedial area of the cerebral cortex influence one another, and how this communication changes over rapid timespans. (neurosciencenews.com)
  • Researchers at the Sainsbury Wellcome Centre at UCL used causal techniques to uncover how two neocortical areas in the brain communicate with one another and found that their influence on each other changes over much faster timescales than previously thought. (neurosciencenews.com)
  • In a new study, published today in Neuron , SWC researchers elucidate how two visual areas in the cerebral cortex, the primary visual cortex (V1) and lateromedial area (LM), influence one another and how this communication changes over rapid timespans. (neurosciencenews.com)
  • Researchers compared the discourse comprehension abilities of patients with damage to specific brain regions relative to patients without damage to those regions. (neurosciencenews.com)
  • In a new study, researchers uncovered the brain mechanisms that underlie discourse comprehension. (neurosciencenews.com)
  • To investigate the brain regions that underlie discourse comprehension, the researchers studied a group of 145 American male Vietnam War veterans who sustained penetrating head injuries during combat. (neurosciencenews.com)
  • The researchers identified a network of brain areas in the frontal and parietal cortex that are essential to discourse comprehension. (neurosciencenews.com)
  • The findings, by researchers at Duke University Medical Center, show that deafness penetrates much more rapidly and deeply into the brain than previously thought. (scitechdaily.com)
  • The researchers have dubbed the canine face-processing region they identified the dog face area, or DFA. (technologynetworks.com)
  • Moving forward, the researchers hope to make better sense of this important region of the brain. (iflscience.com)
  • Photo by Image Point Fr , Shutterstock: Stanford researchers found changes in three areas of the brain that occur when people are hypnotized. (stanford.edu)
  • The power of hypnosis to alter your mind and body like this is all thanks to changes in a few specific areas of the brain, researchers at the Stanford University School of Medicine have discovered. (stanford.edu)
  • While researchers have previously scanned the brains of people undergoing hypnosis, those studies have been designed to pinpoint the effects of hypnosis on pain, vision and other forms of perception, and not the state of hypnosis itself. (stanford.edu)
  • The researchers investigated in this study, supported by the Max Planck Society (MPG) and the German science foundation (DFG), such brain-behavior correlations with the help of three tasks that the study participants had to solve while lying in the MRI scanner. (mpg.de)
  • To advance this vision, we bring together researchers, students, and faculty who study brain science at all levels. (mit.edu)
  • Researchers at BCS are using the latest tools and technologies to unlock critical applications of molecular science, including the prospects of future genetic intervention that might one day lead to cures for brain diseases. (mit.edu)
  • Researchers based their research on brain scans of 30 astronauts. (voanews.com)
  • The Medical Informatics Platform (MIP) is a subproject (SP8) of the Human Brain Project, a large ten-year scientific research project that aims to build a collaborative ICT-based scientific research infrastructure to allow researchers across the globe to advance knowledge in the fields of neuroscience, computing, and brain-related medicine. (chuv.ch)
  • A fingernail-sized wireless brain implant that is powered only by radio waves and can control nerve cells using pulses of light has been developed by researchers in the US. (thenakedscientists.com)
  • Kelly Sarmiento, MPH, serves as a public health advisor in the Division of Injury Prevention's Traumatic Brain Injury Team. (cdc.gov)
  • Kelly's expertise is in pediatric mild traumatic brain injury and she is responsible for leading the HEADS UP campaign. (cdc.gov)
  • In this role, she served as the health communications team lead where she directed educational campaigns on traumatic brain injury and emergency response and provided strategic direction regarding health communication for the division's state injury programs. (cdc.gov)
  • People with traumatic brain injury suffer a variety of challenges depending on the degree and extent of their injury. (brainandspinalcord.org)
  • Traumatic brain injury (TBI), also known as acquired brain injury, head injury, or brain injury, causes substantial disability and mortality. (medscape.com)
  • Humans have at least three face processing regions in the brain, including the fusiform face area, or FFA, which is associated with distinguishing faces from other objects. (technologynetworks.com)
  • I will go out on a limb and say that I think similar changes also occur in human brains after hearing loss, specifically in Broca's area, a part of the human brain that plays an important role in generating speech and that also receives inputs from the auditory system," Mooney said. (scitechdaily.com)
  • Since its discovery in the 1860's, Broca's area has been assumed to be the region of the brain responsible for human speech with responsibilities ranging from language comprehension to actually speaking words. (iflscience.com)
  • Broca's area. (iflscience.com)
  • While Broca's area was quite active when the test subjects were reading the words and determining what to say in their heads, as was expected, the moment they began talking, the area curiously became inactive. (iflscience.com)
  • It has traditionally been believed that language processing and speech production largely came from Broca's area (as well as Wernicke's area), which would have remained active during the actual act of speaking. (iflscience.com)
  • This new finding helps us move towards a less dichotomous view where Broca's area is not a center for speech production, but rather a critical area for integrating and coordinating information across other brain regions. (iflscience.com)
  • The function of Broca's area was first identified when Pierre Paul Broca noticed that those who had suffered strokes or had other brain injuries affecting this particular region of the frontal lobe also had difficulty speaking. (iflscience.com)
  • Broca's area shuts down during the actual delivery of speech, but it may remain active during conversation as part of planning future words and full sentences," Flinker explained. (iflscience.com)
  • There is still much to learn about the function of this area, as there have been instances of damage to Broca's area that did not result in impaired speech. (iflscience.com)
  • Distinct sections of the brain have altered activity and connectivity while someone is hypnotized, they report in a study published online July 28 in Cerebral Cortex. (stanford.edu)
  • Here we demonstrate that direct measurement and comparison of the surface area of the cerebral cortex at a fine scale is possible using mass conservative interpolation methods. (warwick.ac.uk)
  • Microbial enzymes involved in the metabolism of neuroactive compounds such as glutamate and GABA, were also associated with structure of the brain, including the first brain regions to develop such as the cerebellum, and with overall cognitive function. (biorxiv.org)
  • The drug's release modified activity in brain regions targeted by the ultrasound beam. (stanford.edu)
  • Other recent findings discussed show that a pathway between two brain regions, the amygdala and the hippocampus, plays a significant role in anxiety. (indiavision.com)
  • We wanted to study the communication between areas to understand how different brain regions work together to process visual stimuli. (neurosciencenews.com)
  • The function of these rapidly changing influences is not yet known, but the authors hypothesize that they may allow cortical areas to control different aspects of processing in the downstream brain regions they influence over very short time spans. (neurosciencenews.com)
  • Processing of sensory information depends on the interactions between hierarchically connected neocortical regions, but it remains unclear how the activity in one area causally influences the activity dynamics in another and how rapidly such interactions change with time. (neurosciencenews.com)
  • Barbey said these shrapnel-induced injuries typically produced focal brain damage, unlike injuries caused by stroke or other neurological disorders that affect multiple regions. (neurosciencenews.com)
  • This allowed them to compare the discourse comprehension abilities of patients with damage to a particular voxel or cluster of voxels with those of patients without injuries to those brain regions. (neurosciencenews.com)
  • Rather than engaging brain regions that are classically involved in language processing, our results indicate that discourse comprehension depends on an executive control network that helps integrate incoming language with prior knowledge and experience," Barbey said. (neurosciencenews.com)
  • The findings help us understand the neural foundations of discourse comprehension, and suggest that core elements of discourse processing emerge from a network of brain regions that support language processing and executive functions. (neurosciencenews.com)
  • Now that we know which brain regions are involved, we may be able to use this knowledge to alter someone's capacity to be hypnotized or the effectiveness of hypnosis for problems like pain control," said the study's senior author, David Spiegel , MD, professor and associate chair of psychiatry and behavioral sciences. (stanford.edu)
  • It was already known that the inferior parietal lobe (IPL) is one of these regions in the human brain. (mpg.de)
  • At the same time, these areas work together with many other brain regions in a process-specific way. (mpg.de)
  • Moreover, these individual sub-areas then cooperate with different regions of the rest of the brain. (mpg.de)
  • To do this, it links specialized individual areas, such as the IPL, with other more general regions. (mpg.de)
  • Even in great apes, Numssen says, brain regions that correspond to the IPL do not only process purely physical stimuli, but also more complex information. (mpg.de)
  • A promising approach for non-invasive gene delivery to the brain is to administer recombinant adeno-associated viruses (AAVs) intravenously and allow them to cross the BBB at precise FUS-targeted brain regions. (au.dk)
  • To obtain non-invasive gene delivery to multiple brain regions with one area of FUS-BBB modulation, we combined a modified AAV2 vector harboring enhanced retrograde transport properties (AAVrg) with FUS-mediated brain delivery. (au.dk)
  • This allowed for gene delivery from the FUS-targeted site to multiple connected brain regions. (au.dk)
  • Cortical surface area, when considered, has been measured only over gross regions or approached indirectly via comparisons with a standard brain. (warwick.ac.uk)
  • Negentropy Maps as Patterns of the Pathological Alteration Specificity of Brain Regions. (crossref.org)
  • Pain-related brain activity was identified in a matrix of regions using a linear model of the transient BOLD responses to noxious stimulation. (ox.ac.uk)
  • With the aid of Jerry Seinfeld and his friends, as well as the animated characters of the cartoon The Simpsons , Kelley and his colleagues have found that different brain regions spark with activity when a person gets a joke versus when he or she reacts to it. (sciencenews.org)
  • We investigated the relationship of the microbiome with the neuroanatomy and cognitive function of 281 healthy children in a cross-sectional analysis and demonstrated that differences in gut microbial taxa and gene functions are associated with the size of brain regions and with overall cognitive function. (biorxiv.org)
  • Although brain function and behavior are known to be regulated by the N- glycosylation state of numerous cell surface glycoproteins , our current understanding of brain glycosylation is limited, and glycan variations associated with functional brain regions remain largely unknown. (bvsalud.org)
  • Notably, some of these changes were restricted to specific anatomical areas, while others altered according to disease progression across the regions studied. (lu.se)
  • We show how our brains dynamically adapt to changing requirements. (mpg.de)
  • The brain dynamically integrates and coordinates responses to internal and external stimuli across multiple spatiotemporal scales through large-scale functional networks. (nature.com)
  • However, the Georgetown scientists were able to define certain specialized areas within the auditory cortex that the monkeys used specifically to identify the type and location of sound-areas that up until now had not been pinpointed. (sciencedaily.com)
  • This is an interesting discovery for not only basic scientists, but for anyone who studies hearing and brain function," Rauschecker said. (sciencedaily.com)
  • Stanford University School of Medicine scientists have developed a noninvasive way of delivering drugs to within a few millimeters of a desired point in the brain. (stanford.edu)
  • Historically, scientists have recorded from different brain areas and used statistical correlations to infer how one area influences another. (neurosciencenews.com)
  • The scientists scanned the brains of 57 people during guided hypnosis sessions similar to those that might be used clinically to treat anxiety, pain or trauma. (stanford.edu)
  • Scientists at the Max Planck Institute for Human Cognitive and Brain Sciences have now shown that the IPL comes into play when we need to interpret our environment. (mpg.de)
  • In a large study, scientists from the Max Planck Institute for Human Cognitive and Brain Sciences (MPI CBS) in Leipzig and McGill University in Montreal have helped to solve this question. (mpg.de)
  • A tiny wireless brain implant powered by radio waves that uses light to control nerve cells has been developed by scientists in the US. (thenakedscientists.com)
  • Here we propose a novel, highly resolved connectivity mapping approach, using ultrafast functional ultrasound (fUS), which enables imaging of cerebral microvascular haemodynamics deep in the anaesthetized rodent brain, through a large thinned-skull cranial window, with pixel dimensions of 100 μm × 100 μm in-plane. (nature.com)
  • This 3D topographic map ultimately provides evidence for the relevance of comparative connectomics: motor cortical projections known to be convergent are actually segregated in many target areas with unique targeting patterns, a finding that has anatomical value for revealing functional subdomains that have not been classified by conventional methods. (nature.com)
  • This study presents a comprehensive spatial distribution of the cell - membrane enriched N-glycomes associated with five discrete anatomical and functional brain areas, providing evidence for the presence of a previously unknown brain glyco- architecture . (bvsalud.org)
  • Here, we conducted proteomic, phosphoproteomic, and acetylomic analyses of human postmortem tissue samples from AD (Braak stage III-IV, n=11) and control brains (n=12), covering all anatomical areas affected during the limbic stage of the disease (total hippocampus, CA1, entorhinal and perirhinal cortices). (lu.se)
  • People's brains aren't well equipped to deal with the information age," said senior author Ilya Monosov, PhD, an associate professor of neuroscience, of neurosurgery, and of biomedical engineering. (labmanager.com)
  • Understanding how brain areas communicate is one of the oldest questions in neuroscience. (neurosciencenews.com)
  • There has been less attention paid to how much of a role this brain area plays in processing the visual stimuli themselves," said senior author David Freedman, PhD, professor of neuroscience at UChicago. (earth.com)
  • Research in cellular and molecular neuroscience strives to understand the brain at its most fundamental level by studying the mechanisms that control construction and maintenance of cellular and molecular circuits. (mit.edu)
  • Cellular and molecular neuroscience is a deep mystery, but it brings exciting and critical bridges to other facets of brain and cognitive science. (mit.edu)
  • It turns out that the structure and function of brain centers responsible for learning and memory in a wide range of invertebrate species may possibly share the same fundamental characteristics, according to a new study published in the journal Current Biology and performed by University of Arizona neuroscientists Nicholas Strausfeld, Regents' Professor in the Department of Neuroscience, part of the UA's School of Mind, Brain and Behavior, and Gabriella Wolff. (medindia.net)
  • Language-related functions were among the first to be ascribed a specific location in the human brain ( Broca, 1861 ) and have been the subject of intense research for well over a century. (jneurosci.org)
  • In its most general form, this model proposes a frontal, "expressive" area for planning and executing speech and writing movements, named after Broca ( Broca, 1861 ), and a posterior, "receptive" area for analysis and identification of linguistic sensory stimuli, named after Wernicke ( Wernicke, 1874 ). (jneurosci.org)
  • We now know that many pediatric brain tumors may be caused by an underlying cancer predisposition syndrome. (uclahealth.org)
  • TSC is a rare genetic disorder that causes noncancerous (benign) tumors to grow throughout the body, often in the brain. (uclahealth.org)
  • Pediatric brain tumors may be non-cancerous (benign) or cancerous (malignant). (uclahealth.org)
  • We typically categorize these tumors based on where they are in the brain, how they look under a microscope and their genetic features. (uclahealth.org)
  • Brain tumors can rarely present with symptoms mistaken for anorexia nervosa. (northwestern.edu)
  • For almost two decades, neuroscientists have known that this area, called the fusiform face area (FFA), plays a vital role in the brain's ability to recognize faces and objects that an individual has learned to identify. (bioquicknews.com)
  • The article is titled "Cortical Thickness in Fusiform Face Area Predicts Face and Object Recognition Performance. (bioquicknews.com)
  • The results demonstrate that the most concordant area of activation across all four modalities is the right anterior insula, an area typically associated with visceral perception, especially of negative valence (disgust, pain, etc. (nih.gov)
  • First, they saw a decrease in activity in an area called the dorsal anterior cingulate, part of the brain's salience network. (stanford.edu)
  • When it comes to language comprehension, the anterior IPL in the left hemisphere of the brain becomes active. (mpg.de)
  • For attention, it is the anterior IPL in the right side of the brain. (mpg.de)
  • For attention, it is the anterior IPL in the right side of the brain (pink). (mpg.de)
  • Within target areas, various combinations of these four projections were defined based on specific 3D spatial patterns, reflecting anterior-posterior, dorsal-ventral and core-capsular relationships. (nature.com)
  • Our findings show that dogs have an innate way to process faces in their brains, a quality that has previously only been well-documented in humans and other primates,' says Gregory Berns, a neuroscientist at Emory University and the senior author of the study. (technologynetworks.com)
  • Knowing what they do now, Freedman believes their findings could help neuroscientists rethink the brain mechanisms involved in decision-making, visual categorization, and sensory and motor processing, as well as lead to a better understanding of how the brain interprets visuals in order to make decisions. (earth.com)
  • In collaboration with outside experts, we have explored the ways in which brain imaging may illuminate and extend the findings from our regular testing. (jocrf.org)
  • The drug went to work immediately, reducing neural activity in the targeted area - but only while the ultrasound device was active and only where the ultrasound intensity exceeded a certain threshold. (stanford.edu)
  • The research paper "Neural mechanisms of discourse comprehension: A human lesion study" by Aron K Barbey, Roberto Colom, and Jordan H. Grafman will appear in Brain: A Journal of Neurology . (neurosciencenews.com)
  • Our results demonstrate a fundamental causal role of LC neuronal activation in the implementation of attentional control by the selective modulation of neural activity in its target areas," the authors write. (zmescience.com)
  • These results show that the brain's parietal cortex is an important hub for guiding decisions, so now we're even more motivated to move ahead and try to work out the details of neural circuits in this part of the brain that actually carry out these cognitive functions," Freedman said. (earth.com)
  • It also allows us to test hypotheses about brain function by precisely intervening in the system in ways that are not possible in humans, such as neural or genetic manipulations. (mit.edu)
  • An active brain can certainly help in improving memory by strengthening the connections between neural impulses in brain. (medindia.net)
  • This experience suggests the COVID-19 pandemic provided an opportunity for implementing a brain tumor care protocol to facilitate safely decreasing ICU utilization and accelerating discharge home without an increase in complications, readmission or reoperations. (plos.org)
  • Why choose UCLA Health for pediatric brain tumor care? (uclahealth.org)
  • Having a better understanding of the true breadth of function of this region could be beneficial to developing new treatments for those who suffer brain injuries due to stroke, epilepsy, or head trauma. (iflscience.com)
  • Our focus in these important areas will help bring about new treatments for both neurodevelopment diseases like autism, as well as late-onset neurodegenerative diseases like Alzheimer's. (mit.edu)
  • Accelerating the pace of scientific discovery about the brain and helping to find treatments and therapies for some of the world's most devastating diseases. (brown.edu)
  • Treatments can include brain tumor scans and pediatric chemotherapy. (uclahealth.org)
  • These studies also promise new insights into how other brain-related disorders associated with aging alter the functional interplay of neuronal function and connectivity. (mit.edu)
  • The iterative refinement and reuse of models and analyses will lead to identification of Biological Signatures of Diseases and novel classifications of brain disorders, thus more accurate diagnoses and personalized medicine. (chuv.ch)
  • The primary goal of MIP is to allow clinicians and neuroscientist a way to unify otherwise inaccessible data and thereby create one federated venue for storing information related to brain disease and neurological disorders. (chuv.ch)
  • When the larvae develop within the brain they can cause seizures, headaches, cognitive disorders, strokes, and other neurologic problems. (cdc.gov)
  • Long-range coherences in spontaneous brain activity reflect functional connectivity. (nature.com)
  • The areas displayed at right in red and yellow colors indicate significant positive correlations between test performance and densities in the given brain areas. (jocrf.org)
  • Memory for Design, befitting its correlations to spatial thinking, shows similarity to the Spatial brain images above. (jocrf.org)
  • Rauschecker's research, conducted over the past two and a half years, involved four rhesus monkeys, whose brain structure is similar enough to that of humans to draw valid comparisons. (sciencedaily.com)
  • Songbirds also resemble humans and differ from most other animals in that their songs fall apart when they lose their hearing, and this feature makes them an ideal organism to study how hearing loss may affect the parts of the brain that control vocalization, Mooney said. (scitechdaily.com)
  • It also showed how that region of a dog's brain responds more strongly to the scents of familiar humans than to the scents of other humans, or even to those of familiar dogs. (technologynetworks.com)
  • Although these models do not capture the full mental abilities of humans, they are selected such that they likely share evolutionarily conserved neuronal processing mechanisms that will generalize to human brain function. (mit.edu)
  • This would mean that the role individual areas play in shaping each other's activity could be flexible and tailored to the dynamic demands of behavior. (neurosciencenews.com)
  • The Brain & Behavior Research Foundation is committed to alleviating the suffering caused by mental illness by awarding grants that will lead to advances and breakthroughs in scientific research. (bbrfoundation.org)
  • Usually, the different areas in the cerebrum take on a very specific function. (mpg.de)
  • Which side of the brain is affected is also important because the functions of the two halves of the cerebrum (cerebral hemispheres) are not identical. (msdmanuals.com)
  • The brain centers in question are paired, lobed structures first discovered in insects and known as mushroom bodies. (medindia.net)
  • Core facilities include the Korea Brain Bank and lab animal centers. (wikipedia.org)
  • How do morphological alterations caused by chronic pain distribute across the brain? (crossref.org)
  • Histopathological changes in AD have been linked to brain proteome alterations, including aberrant. (lu.se)
  • Histopathological changes in AD have been linked to brain proteome alterations, including aberrant posttranslational modifications (PTMs) such as the hyperphosphorylation of Tau. (lu.se)
  • Neuroscientists from the University of Chicago have found that the area of the brain responsible for planning movements and spatial awareness, known as the posterior parietal cortex (PPC), also plays a major role in decision making, specifically deciding what images should be in the field of view. (earth.com)
  • In experiments involving people with epilepsy, targeted zaps of the lateral orbitofrontal cortex region of the brain helped ease depressive symptoms. (kpbs.org)
  • A study of 25 people with epilepsy found that those who had symptoms of depression felt better almost immediately when doctors electrically stimulated an area of the brain just above the eyes, a team reported Thursday in the journal Current Biology . (kpbs.org)
  • The study utilized the brain scans of seven patients who had been hospitalized due to their epilepsy. (iflscience.com)
  • Epilepsy is a disorder of the brain. (cdc.gov)
  • In 2019, studying monkeys, Monosov's laboratory members J. Kael White, PhD, then a graduate student, and senior scientist Ethan S. Bromberg-Martin, PhD, identified two brain areas involved in tracking uncertainty about positively anticipated events, such as rewards. (labmanager.com)
  • All patients undergoing craniotomy or endoscopic endonasal removal of a brain, skull base or pituitary tumor were included during two non-overlapping periods: March 2019-January 2020 (pre-pandemic epoch) versus March 2020-January 2021 (pandemic epoch with streamlined care protocol implemented). (plos.org)
  • However, more recently it has become clear that MS can involve both the white and grey areas, and there might be two different mechanisms. (msif.org)
  • Washington - A new study has revealed new mechanisms and areas of the brain associated with anxiety and depression, suggesting possible targets to understand and treat these debilitating mental illnesses. (indiavision.com)
  • The MIT Department of Brain and Cognitive Sciences has an ambitious mission: to understand how the mechanisms of the brain give rise to the mind. (mit.edu)
  • These people were in the hospital awaiting surgery and had wires inserted into their brains to help doctors locate the source of their seizures. (kpbs.org)
  • That meant they already had wires inserted into their brains to help doctors locate the source of their seizures. (kpbs.org)
  • Generalized seizures affect both sides of the brain. (cdc.gov)
  • Focal seizures are located in just one area of the brain. (cdc.gov)
  • Simple focal seizures affect a small part of the brain. (cdc.gov)
  • Secondary generalized seizures begin in one part of the brain, but then spread to both sides of the brain. (cdc.gov)
  • It's an important parasite for public health because it can infect the human brain, causing seizures and other neurologic disease. (cdc.gov)
  • They contain cerebrospinal fluid, a clear and watery liquid that flows in and around the brain and spinal cord. (voanews.com)
  • Chris - And you could lay one of these devices alongside say, a nerve, along the spinal cord or onto the brain. (thenakedscientists.com)
  • The hippocampus has become a focus of interest in dementia research because it is the area of the brain involved in verbal memory and learning, but it is very sensitive to the effects of aging and neurological damage. (sciencedaily.com)
  • This suggests that the relationship between brain volume and cognitive performance is complex, and requires further research, say the authors. (sciencedaily.com)
  • All of the research on brain stimulation reflects a move away from the long-held view that depression is caused by a chemical imbalance in the brain. (kpbs.org)
  • Traditionally a lot of focus in MS has been on the white matter but new research highlights the role of the grey matter damage within the brain in MS. (msif.org)
  • In previous research, the Dog Project identified the caudate region of the canine brain as a reward center. (technologynetworks.com)
  • New research from MIT reports that the abilities to curb impulses and to ignore distractions are independent but ultimately controlled by the same area of the brain. (zmescience.com)
  • Finally, based on previous research, the team also controlled for LC activity and norepinephrine release in two brain areas known as the dorsomedial PFC (dmPFC) and the ventrolateral orbitofrontal cortex (vlOFC), where the LC connects to the front area of the brain. (zmescience.com)
  • BCS faculty who are conducting research in this area can be found here. (mit.edu)
  • By focusing on 5hmC's link to stress, the research team, led by Reid Alisch, Ph.D., of the University of Wisconsin, has moved closer to explaining exactly how acute stress alters gene expression in the brain. (bbrfoundation.org)
  • In late 2006, at a professional research conference, our President, David Ransom, discussed with Dr. Richard Haier, a leading researcher on brain imaging and intelligence, the possibility of relating the volumes of defined brain areas measured with structural magnetic resonance imaging (sMRI) to performance on Johnson O'Connor aptitude tests. (jocrf.org)
  • This was just the beginning of intriguing basic research that we hope will lead to breakthroughs in what we know about the brain and ultimately, how individual examinees can benefit from this new approach. (jocrf.org)
  • Brain tumor research is conducted by the Neuro-Oncology Program and the Mayo Clinic Comprehensive Cancer Center . (mayoclinic.org)
  • Launched in October 2013, the Human Brain Project - HBP - is an EU Flagship initiative in which over 80 partners will work together to create a new "ICT-accelerated" vision for brain research and its applications. (chuv.ch)
  • The Human Brain Project on three research areas: future neurosciences, future medicine and future computing. (chuv.ch)
  • In first phase, the Human Brain Project built an integrated system of ICT-based research platforms. (chuv.ch)
  • The ICT-based research platforms are dedicated respectively to Neuroinformatics, Brain Simulation, High Performance Computing, Medical Informatics, Neuromorphic Computing and Neurorobotics. (chuv.ch)
  • The Medical Informatics Platform, led by Dr. Ferath Kherif, acts as a bridge between brain-science research, clinical research and patient care, providing the collaborative infrastructure and tools to improve our knowledge of the human brain. (chuv.ch)
  • This will accelerate medical research and reduce suffering and costs associated with brain diseases. (chuv.ch)
  • We are on the leading edge of brain tumor immunotherapy research. (uclahealth.org)
  • The Korea Brain Research Institute (KBRI) is a research institute in South Korea. (wikipedia.org)
  • Legally enacted in 1998 through the Brain Research Promotion Act, the preliminary feasibility survey took place in 2007. (wikipedia.org)
  • And they recommend regular aerobic exercise to stave off mild cognitive decline, which is especially important, given the mounting evidence showing that regular exercise is good for cognitive function and overall brain health, and the rising toll of dementia. (sciencedaily.com)
  • Regular aerobic exercise seems to boost the size of the area of the brain involved in verbal memory and learning among women whose intellectual capacity has been affected by age, indicates a small study. (sciencedaily.com)
  • Regular aerobic exercise seems to boost the size of the area of the brain (hippocampus) involved in verbal memory and learning among women whose intellectual capacity has been affected by age, indicates a small study published online in the British Journal of Sports Medicine . (sciencedaily.com)
  • A more sort of modern conception is thinking of depression as a circuit dysfunction, meaning that there's something about the way cells in the brain are talking to each other that is not quite right," says Dr. Vikram Rao, an author of the new study and an assistant professor of clinical neurology at UCSF. (kpbs.org)
  • The study appears in Brain: A Journal of Neurology . (neurosciencenews.com)
  • Neuropsychological patients with focal brain lesions provide a valuable opportunity to study how different brain structures contribute to discourse comprehension," Barbey said. (neurosciencenews.com)
  • While studying songbirds, neurologists discovered that when their hearing was lost, their songs fell apart much like human vocalization does, making them an ideal subject to study how hearing loss may affect the parts of the brain that control vocalization. (scitechdaily.com)
  • This study provided a laser-like focus on what happens in the living songbird brain, narrowed down to the particular cell type involved. (scitechdaily.com)
  • Dogs have a specialized region in their brains for processing faces, a new study finds. (technologynetworks.com)
  • This study demonstrates that MR imaging can be used as a non-invasive indication of AAV delivery to the brain, and that the properties of AAV serotypes influence the efficacy of gene delivery to the brain with FUS. (au.dk)
  • Acute stress can increase the presence of a key DNA modification called 5hmC throughout a portion of the brain called the hippocampus, vital in memory and learning, according to a study published in November 2015 in the journal Neurobiology of Disease . (bbrfoundation.org)
  • In the future, they would like to compare this modification in female and male brains (all the mice in the study were male) and determine what role 5hmC may have in gene expression changes related to chronic, long-term stress. (bbrfoundation.org)
  • In late 2010 we made arrangements to collaborate with the MIND Institute for brain imaging, which is affiliated with the University of New Mexico, to conduct a study in which magnetoencephalography (MEG) imaging is used to create a continuous picture (that is, a video) of brain functioning in examinees while they take alternate items for several Foundation tests. (jocrf.org)
  • It is the first time we have found a direct relationship between brain structure and visual expertise," said Isabel Gauthier, Ph.D., David K. Wilson Professor of Psychology at Vanderbilt University, who directed the study. (bioquicknews.com)
  • A new study has found that areas of the brain containing fluid expand when astronauts are on space missions for six months or longer. (voanews.com)
  • The platform is federating hospital and other clinical data on all brain diseases and across multiple levels of biology. (chuv.ch)
  • Because each side of the brain controls movement of the opposite side of the body, damage to the left hemisphere causes weakness on the right side of the body, and vice versa. (msdmanuals.com)
  • Ongoing studies will examine functional specialization directly in the auditory cortex of the human brain using functional magnetic resonance imaging (fMRI). (sciencedaily.com)
  • Functional magnetic resonance imaging (FMRI) was used to identify candidate language processing areas in the intact human brain. (jneurosci.org)
  • If the dogs' response to faces was learned - by associating a human face with food, for example - you would expect to see a response in the reward system of their brains, but that was not the case, Berns says. (technologynetworks.com)
  • Our results provide insight into the basic functioning of the human brain. (mpg.de)
  • However, parts of the IPL are unique to the human brain and are not found in great apes - a hint that this region has evolved in the course of evolution to enable key functions of human cognition. (mpg.de)
  • The mechanism of how human brain processes the language to express and comprehend the verbal, written, gestures and symbols is still a mystery. (medindia.net)
  • Traditionally this part of the brain has been thought to be involved in controlling spatial attention and planning actions. (earth.com)
  • The accompanying figures below show brain areas that are related to indexes derived from spatial and numerical aptitudes. (jocrf.org)
  • To date, only rsfMRI has been able to image intrinsic brain networks with the appropriate spatial resolution and coverage. (nature.com)
  • We offer an unmatched level of care and expertise in our area. (uclahealth.org)
  • If, on the other hand, social skills are required, the posterior parts of the IPL in both hemispheres of the brain spring into action simultaneously. (mpg.de)
  • However, most functions (such as memory) require coordination of several areas in both hemispheres. (msdmanuals.com)
  • Therefore, the IPLs on both sides of the brain probably work together here. (mpg.de)
  • Harmless at the low intensities routinely used for imaging bodily tissues, high-intensity focused ultrasound is approved for the ablation, or deliberate destruction, of certain tissues, including portions of a central brain structure called the thalamus to treat the condition known as essential tremor. (stanford.edu)
  • The ultrasound in these experiments was delivered in a series of short staccato pulses separated by periods of rest, giving the targeted brain tissue plenty of time to cool off between pulses. (stanford.edu)
  • abstract = "Focused ultrasound combined with intravenously injected microbubbles (FUS) is known to non-invasively, locally, and transiently increase the permeability of the blood-brain barrier (BBB). (au.dk)
  • Ilya Monosov, PhD, shows data on brain activity obtained from monkeys as they grapple with uncertainty. (labmanager.com)
  • Activity in those areas drove the monkeys' motivation to find information about good things that may happen. (labmanager.com)
  • Surprisingly, they found that the effect of manipulating one area on the activity in another varied over time on a fast timescale. (neurosciencenews.com)
  • For example, a neuron in area V1 could decrease its activity in response to area LM at one time point but not be influenced by LM activity 100 milliseconds later. (neurosciencenews.com)
  • However, a new paper published in the Proceedings of the National Academy of Sciences explains that activity in this area is rather low when an individual is speaking, which goes against conventional wisdom about the function of this region. (iflscience.com)
  • They were asked to read words aloud from a piece of paper or repeat what another person had said, and their brain activity was analyzed during this time. (iflscience.com)
  • Then, they observed the brains of those 57 participants using functional magnetic resonance imaging, which measures brain activity by detecting changes in blood flow. (stanford.edu)
  • Now we find that indeed, when we temporarily shut the activity down in that part of the brain it really does affect the sensory parts of decisions. (earth.com)
  • Moving closer to knowing how acute stress changes activity of genes in the brain. (bbrfoundation.org)
  • We present a method for investigating the dynamic pharmacological modulation of pain-related brain activity, measured by BOLD-contrast fMRI. (ox.ac.uk)
  • The mapping of specific modulation of pain-related brain activity is directly relevant for understanding pharmacological analgesia. (ox.ac.uk)
  • The method of examining time-dependent pharmacological modulation of specific brain activity may be generalized to other drugs that modulate brain activity other than that associated with pain. (ox.ac.uk)
  • Yann Mineur, PhD, abstract revealed that decreasing a chemical signal in the amygdala, a brain area associated with emotional processing, produces antidepressant-like effects in mice. (indiavision.com)
  • Further emphasis has been placed on the white matter as areas of damage in these areas are readily detected in MRI scans, and experimental models of MS are made by generating an immune response against myelin. (msif.org)
  • They went on to show in experimental models of MS, that when immune cells targeting beta-synuclein were added, they were able to get through the blood brain barrier and cause a flare of symptoms. (msif.org)
  • Our results demonstrate that the AAV serotype, the extent of FUS-induced BBB permeability, and the intrinsic properties of the targeted brain tissue influence the observed biodistribution, diffusion and transduction of AAV to cells of the cerebrovasculature and brain parenchyma. (au.dk)
  • Here, we constructed a whole-brain, three-dimensional (3D) map showing the tract pathways and targeting locations of these four motor cortical outputs in mice. (nature.com)
  • We report the cell membrane N-glycome of two major developmental divisions of mice brain with specific and distinctive functions, namely the forebrain and hindbrain . (bvsalud.org)
  • frequency depends upon area. (cdc.gov)
  • The nerve cells that showed changes after deafening send signals to the basal ganglia, a part of the brain that plays a role in learning and initiating motor sequences, including the complex vocal sequences that make up birdsong and speech. (scitechdaily.com)
  • Chris - The idea being you'd send the energy in with the radio waves it would make the LED light up and put light of the right colour into the brain and stimulate those nerve cells. (thenakedscientists.com)
  • This medical exhibit depicts the brain from four different views using color-coding to show the anatomy and functional areas. (smartimagebase.com)
  • Freedman and Zhou wanted to see if the lateral intraparietal area (LIP), a specific area of the PPC, was involved in making these decisions. (earth.com)
  • The primary (MOp) and secondary (MOs) motor cortices are known to produce specific output projections that are targeted to both similar and different target areas. (nature.com)
  • Region-Specific Cell Membrane N-Glycome of Functional Mouse Brain Areas Revealed by nanoLC-MS Analysis. (bvsalud.org)
  • In this work , we used a well-established cell surface glycomic nanoLC-Chip-Q-TOF platform developed in our laboratory to characterize the N-glycome of membrane fractions enriched in cell surface glycoproteins obtained from specific functional brain areas. (bvsalud.org)
  • Region-specific glycan maps were obtained with â ¼120 N- glycan compositions in each region, revealing significant differences in " brain -type" glycans involving high mannose , bisecting, and core and antenna fucosylated species. (bvsalud.org)
  • The region-specific molecular glyco fingerprints identified here will enable a better understanding of the critical biological roles that N- glycans play in the specialized functional brain areas in health and disease . (bvsalud.org)
  • Because different areas of the brain control specific functions, the location of brain damage determines the type of dysfunction that results. (msdmanuals.com)
  • Specific patterns of dysfunction can be related to the area of the brain that has been damaged. (msdmanuals.com)
  • They ask questions designed to evaluate specific brain functions. (msdmanuals.com)
  • Most proteomic studies to date have focused on AD progression across different stages of the disease, by targeting one specific brain area at a time. (lu.se)
  • however, the key elements influencing, guiding, and monitoring the success of FUS-AAV delivery to the brain remain largely unknown. (au.dk)
  • Single-neuron studies in animals remain indispensable nevertheless," Rauschecker says, "if one really wants to understand in sufficient detail how our brain processes such highly complex sounds. (sciencedaily.com)
  • Language, empathy, attention - as different as these abilities may be, one brain region is involved in all these processes: The inferior parietal lobe (IPL). (mpg.de)