• This review focuses on cutaneous diseases that are either specific to the male genitalia or frequently involve this body region. (medscape.com)
  • 1] This article focuses on cutaneous paraneoplastic syndromes caused by solid tumors. (medscape.com)
  • Cutaneous squamous cell carcinoma (SCC) is an invasive malignant neoplasm of epidermal keratinocytes showing squamous phenotypic differentiation (see the following image). (medscape.com)
  • Bowen disease (BD) is a squamous cell carcinoma in situ (SSCIS) with full-epidermal thickness dysplasia that has the potential for significant lateral spread before invasion. (medscape.com)
  • See Squamous Cell Carcinoma , Bowen Disease , and Actinic Keratosis for more information. (medscape.com)
  • The majority (70%) of cutaneous squamous cell carcinoma (SCC) occurs on the head and neck, with an additional 15% found on the upper extremities. (medscape.com)
  • Sebaceous carcinoma, also known as sebaceous gland carcinoma (SGc), sebaceous cell carcinoma, and meibomian gland carcinoma is an uncommon malignant cutaneous tumor. (wikipedia.org)
  • Cystic fibrosis transmembrane conductance regulator is helpful in the distinction of extra-mammary Paget's disease from squamous cell carcinoma in situ (Bowen's disease). (dermnetnz.org)
  • Al-Arashi MY, Byers HR. Cutaneous clear cell squamous cell carcinoma in situ : clinical, histological and immunohistochemical characterization. (dermnetnz.org)
  • Perineural Invasion of Cutaneous Squamous Cell Carcinoma and Basal Cell Carcinoma: Raising Awareness and Optimizing Management. (dermacompass.net)
  • ASIP and TYR pigmentation variants associate with cutaneous melanoma and basal cell carcinoma. (dermacompass.net)
  • Expression of p40 in Primary Cutaneous Mucinous Carcinoma Versus Primary Mucinous Carcinomas of the Breast and Colon. (jefferson.edu)
  • Mammary Paget's Disease (MPD) is defined as an in situ carcinoma of the nipple and areola. (jcimcr.org)
  • RESULTS: The imaging biomarkers differentiated two separate disease subgroups, having the same histopathologic diagnosis, classic invasive lobular carcinoma. (bvsalud.org)
  • Basal cell carcinoma-mimicking lesions in korean clinical settings. (shengsci.com)
  • SCC in situ ( Bowen disease ) is confined to the epidermis and does not invade the basal membrane. (logicalimages.com)
  • The histology is typically well-differentiated and may appear entirely in situ (Bowen disease). (logicalimages.com)
  • Pathology review of the skin biopsy at our center confirmed presence of Paget's disease, additional imaging excluded intramammary lesions. (jcimcr.org)
  • Introduction to cutaneous pathology. (markahurt.com)
  • In eczematous lesions not responding to topical treatment, a biopsy is needed for further diagnosis and to exclude Paget's disease. (jcimcr.org)
  • Accordingly, many cutaneous lesions can mimic BCCs and differential diagnosis is difficult. (shengsci.com)
  • commonly presents as a painless, red and brown or red and yellow, ulcerated papule on the head or neck and may mimic nonmelanoma skin cancers, molluscum contagiosum, adnexal neoplasms, or pyogenic granuloma. (wikipedia.org)
  • Cutaneous adnexal tumors. (markahurt.com)
  • The differential diagnosis when encountering a high-grade B-cell malignancy at a cutaneous site is broad and includes primary cutaneous follicle center lymphoma (PCFCL), primary cutaneous diffuse large B-cell lymphoma, leg type (PCDLBCL-LT), high-grade B-cell lymphoma with MYC and BCL2 rearrangements (HGBCL- MYC/BCL2 ), and other potential entities which must all be carefully considered before rendering a final diagnosis. (hindawi.com)
  • Extramammary Paget's disease is a rare malignancy of the skin. (jcimcr.org)
  • A wide range of cutaneous signs may be related to internal malignancy. (medscape.com)
  • The alteration of metabolic pathways is a critical strategy for cancer cells to attain the traits necessary for metastasis in disease progression. (biomed.news)
  • Relative to Bowen disease, actinic keratosis (AK) only occurs on sun-damaged skin, is usually smaller, and retains a squamous differentiation toward the surface, often even when dermal invasion is developing. (medscape.com)
  • DNA oxidation appears to have a key role in early carcinogenesis, protein oxidation in all stages of carcinogenesis, and lipid oxidation in lates stages of carcinogenesis in Bowen disease, actinic keratosis, and SCC. (medscape.com)
  • The observation of extraocular SGc arising from Bowen disease or actinic keratosis and the predisposition of SGc to arise in sun-exposed areas suggest a role for ultraviolet exposure or intraepidermal neoplasia in the pathogenesis of some SGc in sun-exposed areas. (wikipedia.org)
  • SGc accounts for approximately 0.7% of all skin cancers and 0.2 to 4.6% of all malignant cutaneous neoplasms. (wikipedia.org)
  • CFTR positivity has also been suggested to support the diagnosis of extramammary Paget's disease. (dermnetnz.org)
  • Skin biopsy showed presence of Paget's Disease. (jcimcr.org)
  • Histology confirmed extramammary Paget's disease. (jcimcr.org)
  • We present a case of Paget's disease located in the inframammary fold without any relation to the nipple or mammary glandular tissue. (jcimcr.org)
  • Paget's disease was confirmed and she was referred to a gynecologist. (jcimcr.org)
  • Cutaneous Paget's disease. (markahurt.com)
  • Carcinoid Syndrome Carcinoid syndrome develops in some people with carcinoid tumors and is characterized by cutaneous flushing, abdominal cramps, and diarrhea. (msdmanuals.com)
  • New cutaneous tumors. (markahurt.com)
  • P53 is a tumor suppressor gene located on chromosome 7 whose mutations have been linked to cutaneous SCC (40-50% incidence). (medscape.com)
  • We describe two cases of rectal herpes simplex virus (HSV) infection in men that clinically mimicked rectal adenocarcinoma. (hindawi.com)
  • Extramammary Paget disease (EMPD) on the other hand is a rare adenocarcinoma of the skin and should be treated accordingly. (jcimcr.org)
  • Paget disease: The changes can mimic the pagetoid variant of SCCIS. (dermnetnz.org)
  • Cutaneous involvement by systemic DLBCL NOS is an infrequent clinical presentation, encountered in only 1.5-3.5% of cases, while disseminated cutaneous disease with multiple subcutaneous nodules at the time of diagnosis is unusual and can present a diagnostic challenge. (hindawi.com)
  • This manuscript elaborates on 3 important and current issues: the emerging role of human papilloma virus (HPV) in oropharyngeal cancer (OPC), current considerations in systemic therapy for advanced disease, and evolving treatment of the neck. (jnccn.org)
  • A diagnostic biopsy is often delayed due to the slow progression of disease, patient reluctance to undergo biopsy, technical difficulties, or prolonged treatment of a suspected benign condition. (logicalimages.com)
  • Cytokeratin 10-negative nested pattern enables sure distinction of clonal seborrheic keratosis from pagetoid Bowen's disease. (dermnetnz.org)
  • AD is one of the most common childhood diseases and has a complex etiology involving genetic and environmental factors. (shengsci.com)
  • Major microbial infections associated with hedgehogs include bacteria such as Salmonella and Mycobacteria , as well as some fungal and viral diseases ( 2 ). (cdc.gov)
  • The early appearance may mimic that of more benign conditions such as verruca , chronic paronychia , or infection. (logicalimages.com)
  • abstract: BACKGROUND:Atopic dermatitis, a chronic recurrent disease, is frequently encountered in clinical practice. (shengsci.com)
  • This review will focus only on common VID, and a few rare conditions with characteristic features such as Crohn's disease, plasma cell vulvitis, acantholytic disorder of genitocrural area, desquamative vulvitis, and atrophic vulvovaginitis. (jsstd.org)
  • However, as long-standing Bowen disease frequently shows evidence of microinvasion on serial histologic cuts, it is typically treated as aggressively as invasive SCC. (logicalimages.com)
  • Bowenoid papulosis: This entity may well represent Bowen disease on the genitalia , and is typically histologically indistinguishable. (dermnetnz.org)
  • The International Society for the Study of Vulvovaginal Disease (ISSVD) has classified VID based on histological reaction patterns [ Table 1 ]. (jsstd.org)
  • Although rare in the United States and minimally emphasized in medical schools, some infectious diseases are showing resurgence because of increased world emigration and the spread of resistant forms of disease. (medscape.com)
  • 8 Knösel T, Schewe C, Petersen N, Dietel M, Petersen I. Prevalence of infectious pathogens in Crohn's disease. (autopsyandcasereports.org)
  • CLASSIFICATION OF DISEASES AND INJURIES I. INFECTIOUS AND PARASITIC DISEASES (001-139) Includes: diseases generally recognized as communicable or transmissible as well as a few diseases of unknown but possibly infectious origin Excludes: acute respiratory infections (460-466) influenza (487. (cdc.gov)
  • certain localized infections Note: Categories for "late effects" of infectious and parasitic diseases are to be found at 137. (cdc.gov)
  • We report a case of a 31-year-old male on chronic prednisone treatment for Crohn's disease who unexpectedly died. (autopsyandcasereports.org)
  • Head and neck cancer (HNC) is a heterogeneous combination of various sites and types of disease. (jnccn.org)
  • Skin biopsies were taken from treated cases of Hansen's disease at tertiary centers in Kolkata and at Raipur who had bacterial index (BI) unchanged or increased compared to their pretreatment BI. (e-ijd.org)
  • US Centers for Disease Control and Prevention (CDC) recommendations are stressed, and promising experimental treatments are noted. (medscape.com)
  • Centers for Disease Control and Prevention. (cdc.gov)
  • The World Health Organization (WHO) classification of Bowen disease includes cases occurring in sun-exposed as well as sun-protected skin. (medscape.com)
  • Compromised skin terrain from underlying chronic conditions such as chronic ulcers, lichen sclerosus et atrophicus , bullous diseases, and some genodermatosis result in increased susceptibility to the development of SCC. (medscape.com)
  • Skin diseases in Asian individuals that you do not want to miss: A selection of unique or relatively more common conditions in Asian populations. (jefferson.edu)
  • The Effects of a Fasting Mimicking Diet on Skin Hydration, Skin Texture, and Skin Assessment: A Randomized Controlled Trial. (ucdavis.edu)
  • Erythroplasia of Queyrat refers to Bowen disease on the glans penis. (medscape.com)
  • IRIS, which is also known as immune restoration disease, refers to a disease- or pathogen-specific inflammatory response that may be triggered after ART initiation in treatment-naive patients, after re-initiation of ART, or after a change to a more effective ART regimen in patients who fail to achieve viral suppression. (hivguidelines.org)
  • Refers to the worsening of a previously diagnosed disease after ART initiation. (hivguidelines.org)
  • Our understanding of mitochondrial transcription in mammalian cells has largely progressed, but the mechanisms regulating mtDNA gene expression are still poorly understood despite their profound importance for human disease. (biomed.news)
  • Here, we review mechanisms of mitochondrial gene expression with a focus on the recent findings in the field of mammalian mtDNA transcription and disease phenotypes caused by defects in proteins involved in this process. (biomed.news)
  • 027.8 Other 027.9 Unspecified OTHER BACTERIAL DISEASES (030-041) Excludes: bacterial venereal diseases (098. (cdc.gov)
  • It is provided as an additional code where it is desired to identify the bacterial agent in diseases classified elsewhere. (cdc.gov)
  • Childhood leprosy is an important marker of the status of the ongoing leprosy control programme, as it is an indicator of active disease transmission in the community. (e-ijd.org)
  • Radiotherapy (RT) and concurrent cisplatin is the most commonly used nonsurgical platform for locally advanced disease. (jnccn.org)
  • Autoimmune vesiculobullous conditions, drug-induced vulvar dermatoses and many such, which occur as part of generalized disease, are not discussed here. (jsstd.org)
  • AIDS-like syndrome: AIDS-like disease (illness) (syndrome) ARC AIDS-related complex Pre-AIDS AIDS-related conditions Prodromal-AIDS 3. (cdc.gov)
  • We suspect, that a similar genomic reduction if happens in treated cases of Hansen's disease, can be a determining factor for developing persisters and relapse. (e-ijd.org)
  • The present study aimed to find out if there was any evidence of genomic reduction in treated cases of Hansen's disease that showed microbiological nonresponse. (e-ijd.org)
  • We concluded that there was evidence of genomic reduction, which might lead to microbiological nonresponse in treated cases of Hansen's disease. (e-ijd.org)
  • This early complication is seen most often within the first 8 weeks of therapy in patients with advanced HIV disease. (hivguidelines.org)
  • While there are markedly increased rates of cutaneous neoplasms in solid organ transplant recipients, there is evidence to suggest that solid organ transplantation may increase the risk of SGc up to 90 times. (wikipedia.org)
  • In addition to the contact urticaria that has been reported in some hedgehog handlers ( 7 ) hedgehogs pose a risk for a number of potential zoonotic diseases ( 2 ). (cdc.gov)
  • Sfrp2, a Wnt inhibitor, is involved in the developmental and disease processes of various cells and tissues by modulating the Wnt pathway. (shengsci.com)
  • An undesirable disease- or pathogen-specific inflammatory response that may be triggered by ART-associated immune system recovery. (hivguidelines.org)
  • The importation of these pets from Africa to the United States has been prohibited since 1991 (Title 9 Code of Federal Regulations Section 93.701) due to their potential to carry foot-and-mouth disease, a foreign animal disease of serious economic concern to the livestock industry ( 6 ). (cdc.gov)
  • Right-sided valvular heart disease may develop after. (msdmanuals.com)