Borrelia burgdorferi species. Medical search. Frequent questions

Lyme disease, caused by the spirochetal bacterium, Borrelia burgdorferi sensu lato (Bbsl), is typically transmitted by hard-bodied ticks (Acari: Ixodidae). (canlyme.com)
Borrelia burgdorferi is a bacterial species of the spirochete class in the genus Borrelia, and is one of the causative agents of Lyme disease in humans. (wikipedia.org)
Along with a few similar genospecies, some of which also cause Lyme disease, it makes up the species complex of Borrelia burgdorferi sensu lato. (wikipedia.org)
B. burgdorferi sensu stricto exists in North America and Eurasia and until 2016 was the only known cause of Lyme disease in North America. (wikipedia.org)
B. burgdorferi is the causative agent of Lyme disease and is why this bacteria is so important and being studied. (wikipedia.org)
Lyme disease is caused by bacteria called Borrelia burgdorferi ( B burgdorferi ). (medlineplus.gov)
In areas where Lyme disease is endemic or emerging, vaccinate dogs against Borrelia burgdorferi and reducing the risk of infection through year-round tick control and avoiding areas with ticks. (capcvet.org)
Lyme disease is caused by a bacterial infection with certain Borrelia species. (cdc.gov)
Lyme disease is caused by the bacterial spirochetes of the genus Borrelia--most commonly Borrelia burgdorferi in North America--which is transmitted by the bite of an infected tick. (pethealthnetwork.com)
Other species of ticks have been found to transmit Lyme disease in Europe and Asia. (pethealthnetwork.com)
When an infected tick bites, it takes twenty-four to forty-eight hours for the tick to transmit Borrelia burgorferi, the spirochete that causes Lyme disease. (pethealthnetwork.com)
If the test is positive, it means your pet was infected with the spirochete Borrelia but does not necessarily mean your pet has Lyme disease. (pethealthnetwork.com)
1] "Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi. (tcdb.org)
In eastern North America, the vector of the Lyme disease causing bacterium B. burgdorferi sensu stricto ( B. burgdorferi s.s. hereafter) is the blacklegged tick, Ixodes scapularis , which has three parasitic stages in its life cycle: larva, nymph, and adult. (nature.com)
Schedule Free Consultation Lyme disease is caused by 4 species of bacteria. (checkbiotech.org)
Borrelia burgdorferi and Borrelia mayonnii are the ones responsible for Lyme disease in. (checkbiotech.org)
The next day, the assay showed elevated Borrelia immunoglobulin G (IgG) (498 U/mL) and immunoglobulin M (IgM) (2.7 U/mL) levels, and a positive IgG and IgM Borrelia immunoblot, confirming the diagnosis of Lyme disease. (cmaj.ca)
So, to calculate the relative risk of getting ehrlichiosis compared to Lyme disease, we multiplied the abundance of lone star ticks times the chance of their being infected with Ehrlichia , and then divided that by the abundance of blacklegged ticks times their chance of their being infected with Borrelia burgdorferi . (cdc.gov)
Neither the bird blood samples nor the ticks tested positive for Borrelia burgdorferi, a bacterial species that causes Lyme disease. (texastribune.org)
Over the past two decades, Ixodes scapularis , the primary tick vector of the Lyme disease pathogen Borrelia burgdorferi in North America has expanded its range northward from the USA to colonize new regions in southern Canada. (britishecologicalsociety.org)
Predicting spatio-temporal population patterns of Borrelia burgdorferi , the Lyme disease pathogen. (britishecologicalsociety.org)
Of the 36 known species of Borrelia, 12 are distinguished to cause Lyme disease or borreliosis and are transmitted by ticks. (prospecbio.com)
The main Borrelia species causing Lyme disease are Borrelia burgdorferi, Borrelia afzelii, and Borrelia garinii. (prospecbio.com)
In Europe, several reservoir hosts for Lyme disease-associated Borrelia spp. (biomedcentral.com)
Lyme disease, known commonly outside the U.S. as Lyme borreliosis, is caused by infection with tick-borne spirochetes of the Borrelia burgdorferi sensu lato complex. (health.mil)
In North America, the vast majority of Lyme disease is caused by B. burgdorferi sensu stricto, 1 although other presumably pathogenic genospecies have been isolated. (health.mil)
3. Lyme Borrelia burgdorferi Test (CPT: 86617)-Borrelia burgdorferi (Lyme Disease) by Western Blot analysis. (immed.org)
Chronic Fatigue Syndrome patients subsequently diagnosed with Lyme Disease Borrelia burgdorferi: evidence for Mycoplasma species co-infections. (immed.org)
Hikers in wooded areas must check themselves carefully for attached ticks, as Borrelia burgdorferi -carrying ticks transmit Lyme disease to humans through biting. (the-scientist.com)
the fourth, the western black-legged tick, which can transmit Borrelia burgdorferi - the bacteria that causes Lyme Disease - is found primarily in western Washington. (methowvalleynews.com)
Lyme disease is usually caused by the bacterium Borrelia burgdorferi and rarely, Borrelia mayonii. (lebanonturf.com)
What if we could vaccinate the white-footed mice that account for the majority of the transmission of Borrelia burgdorferi (the cause of Lyme disease) and significantly reduce the level of tick infection? (caryinstitute.org)
When ticks later fed on the mice, the ingested antibodies killed the Borrelia and prevented the transmission of Lyme disease. (caryinstitute.org)
The CDC recently linked Lyme disease with several deaths due to cardiac disease caused by Borrelia. (caryinstitute.org)
the black-legged tick (Ixodes scapularis) is responsible for transmission of A. phagocytophilum in the upper Midwest and northeastern U.S. These tick species also transmit the agents of Lyme disease (Borrelia burgdorferi) and babesiosis (Babesia species). (medgadget.com)
Those are the words--and the multiple exclamation points--of Tara Moriarty, proprietor of the Moriarty Lab , an infectious diseases research lab that studies primarily Borrelia burgdorferi (Bb) the bacterium that causes Lyme disease. (huffpost.com)
Anaplasmosis, babesiosis, ehrlichiosis, Lyme disease, and Rocky Mountain spotted fever can be spread by ticks to humans and various species of livestock and companion animals. (msu.edu)
The Ixodes scapularis tick in the eastern U.S. and Ixodes pacificus tick in the western U.S. are commonly termed deer ticks, or blacklegged ticks, and can carry Lyme disease caused by Borrelia burgdorferi . (msu.edu)
Borrelia mayoanii , a recently identified bacterium which also causes Lyme disease, is found in Ixodes scapularis ticks in the upper Midwest. (msu.edu)
Detection of antibodies to Borrelia burgdorferi, the causative agent of Lyme disease, by indirect fluorescent antibody test. (tamu.edu)
Lyme Borreliosis (Borrelia burgdorferi) DNA is not typically detected in peripheral blood, even when Lyme disease is the cause of clinical signs. (tamu.edu)
Caused by infection with the spirochetal (helical) bacteria Borrelia burgdorferi, Lyme disease is primarily transmitted to humans , as well as dogs , horses and other domesticated animals, by the bite of infected ticks . (newworldencyclopedia.org)
Lyme disease is caused by spirochetal bacteria from the genus Borrelia , which has well over 300 known genomic strains. (newworldencyclopedia.org)
The Borrelia species known to cause Lyme disease are collectively known as Borrelia burgdorferi sensu lato, and have been found to have greater strain diversity than previously estimated. (newworldencyclopedia.org)
Some of these species are carried by ticks not currently recognized as carriers of Lyme disease. (newworldencyclopedia.org)
Another related species, Borrelia mayonii (B. mayonii), has also been shown to cause Lyme disease in the upper midwestern United States (3,4). (cdc.gov)
Dr Paul Auwaerter discusses a scientist's proposal to rid areas prone to Lyme disease by making the mice immune to infection with Borrelia burgdorferi, thus breaking the transmission cycle. (medscape.com)
What Clinicians Should Know About the New Lyme Species Borrelia burgdorferi isn't the only bacterial species causing Lyme disease in the United States. (medscape.com)

Borrelia burgdorferi is named after the researcher Willy Burgdorfer, who first isolated the bacterium in 1982. (wikipedia.org)
B. burgdorferi is a microaerobic, motile spirochete with seven to 11 bundled perisplasmic flagella set at each end that allow the bacterium to move in low- and high-viscosity media alike, which is related to its high virulence factor. (wikipedia.org)
In their latest study, Matthew Pine and Norbert Pardi from the University of Pennsylvania developed an OspA-based mRNA vaccine that prevents the bacterium Borrelia burgdorferi from infecting mice. (the-scientist.com)
It is caused by a bacterium belonging to the Borrelia burgdorferi sensu lato group, which includes at least 5 species that are pathogenic to humans, and is present in France. (anses.fr)
People get this disease from ticks infected with a bacterium, Borrelia burgdorferi . (biologicaldiversity.org)
Ticks feed on different species, and, since many are poor hosts for the bacterium, only a limited number of ticks would carry the disease to people. (biologicaldiversity.org)
[9] The genome of B. burgdorferi includes a linear chromosome approximately one megabase in size, and 21 plasmids (12 linear and 9 circular)-the largest number of plasmids (double-stranded DNA molecules separate from the chromosomal DNA ) found in any known bacterium [10] . (newworldencyclopedia.org)

B. burgdorferi sensu stricto (s.s. (biomedcentral.com)
2-5 Pathogen diversity is greater in Europe, where B. burgdorferi sensu stricto, B. afzelii , B. garinii , B. bavariensis , and B. spielmanii are established contributors to the burden of human disease. (health.mil)
B. burgdorferi sensu stricto (predominant in North America, but also in Europe), B. afzelii, and B. garinii (both predominant in Eurasia). (newworldencyclopedia.org)
At present, diagnostic tests are based only on B. burgdorferi sensu stricto (the only species present in the United States), B. afzelii, and B. garinii. (newworldencyclopedia.org)
Here we obtained a well-resolved polymorphism type of intergenic spacer (IGS) sequence phylogeny of B. burgdorferi sensu stricto clonal complexes (corresponding to the ospC- A and -B groups) is associated by using multilocus sequence typing at housekeeping loci with hematogenous dissemination in patients with early as well as loci under adaptive evolution. (cdc.gov)

Not all species of ticks can carry these bacteria. (medlineplus.gov)
Nymphs pick up bacteria when they feed on small rodents, such as mice, infected with B burgdorferi . (medlineplus.gov)
But current diagnostic tests are not very reliable - they use indirect methods, measuring antibodies the body produces against the Borrelia bacteria that cause the disease. (acs.org)
These include Borrelia Burgdorferi, Borellia Mayonii, Borrelia afzelii and Borrelia Garinii bacteria. (checkbiotech.org)
Andrea Egizi] Ehrlichiosis is the name of a human disease caused by a particular species of bacteria, in the genus Ehrlichia . (cdc.gov)
Borrelia belongs to a genus of bacteria of the spirochete phylum. (prospecbio.com)
Digitally colorized scanning electron microscope image depicting a grouping of numerous, Gram-negative anaerobic Borrelia burgdorferi bacteria derived from a pure culture. (health.mil)
3 Borrelia burgdorferi (a gram negative bacteria) binds several glycosphingolipids including GT 1b . (matreya.com)
Scientists are particularly concerned about ticks transmitting bacteria from the Borrelia burgdorferi sensu lato complex-a group of spirochetes that includes the originally discovered species, B. burgdorferi . (the-scientist.com)
OspA is widely conserved among the bacteria in the B. burgdorferi sensu lato complex, which makes it a great target. (the-scientist.com)
Certain species of Clostridium bacteria induce disease by producing powerful toxins. (livestrong.com)
A related species called Bacillus cereus causes food poisoning mediated by toxins the bacteria produce. (livestrong.com)
Borrelia species are considered diderm (double-membrane) bacteria rather than Gram-positive or negative. (creative-biolabs.com)
It is caused by Borrelia burgdorferi and other closely related species of bacteria. (justtouch.com)
One of the most striking features of B. burgdorferi as compared with other bacteria is its unusual genome, which is far more complex than that of its spirochetal cousin Treponema pallidum, the agent of syphilis. (newworldencyclopedia.org)

Bacterial transformation has been utilized by researchers in order to isolate specific pathogenic genes among the Borrelia burgdorferi. (wikipedia.org)
B. burgdorferi strains appear to be highly insufficient for use in bacterial transformation due to the large amount of DNA needed for transformation, the time it takes to produce reliable transformants, and the influence of restriction modification systems. (wikipedia.org)
In fact, infectivity of B. burgdorferi often requires the gene pncA, which is present on a bacterial plasmid that contains the gene bbe02 that is highly selected against during transformation. (wikipedia.org)
Her main research interests have been the study of Mur ligases from different bacterial species and the search for inhibitors of these enzymes. (degruyter.com)
For more than 30 years, his main research interests have been the functional and structural study of the enzymes of peptidoglycan biosynthesis, the determination of the structure of peptidoglycan from certain bacterial species, and the search for peptidoglycan biosynthesis inhibitors that could act as antibacterial agents. (degruyter.com)
Among the Gram-negative cocci, two specific bacterial species stand out as important human pathogens. (livestrong.com)
A number of bacterial species in the broad category of Gram-negative rods can cause human infections, which range in severity and site of the body affected. (livestrong.com)
Borrelia burgdorferi is a bacterial species of the spirochete class of the genus Borrelia. (creative-biolabs.com)
It is caused by an infection with Borrelia burgdorferi , a bacterial species. (wordinfo.info)
The A and B clones of Borrelia burgdorferi sensu stric- maintenance of these clonal complexes in natural bacterial to, distinguished by outer surface protein C ( ospC ) gene populations ( 3 , 4 ). (cdc.gov)

B. burgdorferi is a slow-growing microaerophilic spirochete with a doubling time of 24 to 48 hours. (wikipedia.org)
Ticks can transmit B. burgdorferi to humans, but humans are dead-end hosts, unlikely to continue the life cycle of the spirochete. (wikipedia.org)
The spirochete was named Borrelia burgdorferi in his honor. (newworldencyclopedia.org)
Apart from this group of closely related genospecies, additional Borrelia species of interest include B. lonestari, a spirochete recently detected in the Amblyomma americanum tick (Lone Star tick) in the U.S. [7] B. lonestari is suspected of causing STARI (Southern Tick-Associated Rash Illness), also known as Masters disease in honor of its discoverer. (newworldencyclopedia.org)
The genetic homogeneity of ospC -A isolates was confi rmed agent, Borrelia burgdorferi , a spirochete that parasitizes by sequences at 6 additional chromosomal housekeeping vertebrates, is transmitted by hard-bodied ticks through- loci ( gap, alr, glpA, xylB, ackA, and tgt ). (cdc.gov)

Despite the common findings of antibodies reactive to B. burgdorferi in cats in endemic areas, natural disease caused by infection in cats - if it occurs at all - is poorly understood. (capcvet.org)
Specific antibodies to B. burgdorferi sensu lato and Bartonella sp. (medscimonit.com)
These findings on cardiovascular MRI in combination with positive Borrelia IgM antibodies were strongly suggestive of Lyme carditis. (cmaj.ca)

In the U.S., essentially, all cases are due to infection with Borrelia burgdorferi. (cdc.gov)

B. burgdorferi circulates between Ixodes ticks and a vertebrate host in an enzootic cycle. (wikipedia.org)
The European tick Ixodes ricinus is the vector of several potential human pathogens, of which Borrelia burgdorferi sensu lato (s.l.) and tick-borne encephalitis virus (TBEV) are the most important and well-known in human medicine. (frontiersin.org)
The present study investigated the prevalence of Borrelia burgdorferi sensu lato (s.l.) genospecies in Ixodes ricinus ticks collected in Hanover, Northern Germany, in 2010. (biomedcentral.com)
Anaplasmosis caused by Anaplasma phagocytophilum and babesiosis caused by several species of Babesia are transmitted by Ixodes ticks. (msu.edu)

The Borrelia genus members have a linear chromosome which is about 900 kbp in length as well as an excess of both linear and circular plasmids in the 5-220 kbp size range. (prospecbio.com)

Higher Prevalence of Babesia microti than Borrelia burgdorferi in Small Mammal Species in Central Pennsylvania, United States. (bvsalud.org)

Additional B. burgdorferi sensu lato genospecies are suspected of causing illness, but are not confirmed by culture. (newworldencyclopedia.org)

Recombinant Borrelia Afzelii Outer Surface Protein p100 produced in SF9 is a glycosylated, polypeptide chain having a calculated molecular mass of 74,782 Dalton. (prospecbio.com)
Borrelia Afzelii p100 is expressed with a 10xHis tag at N-terminus and purified by proprietary chromatographic techniques. (prospecbio.com)
Borrelia Afzelii p100 is supplied in 20mM HEPES buffer pH-7.6, 250mM NaCl and 20% glycerol. (prospecbio.com)

1 Currently, there are no serologic tests available for B. mayonii infection, but cross-reactivity with B. burgdorferi testing may occur. (cdc.gov)

Our findings show that Bbsl is present in all provinces, and that multiple tick species are implicated in the enzootic maintenance cycle of this pathogen. (canlyme.com)
Presence of DNA of yet uncultured and undescribed species of Bartonella in eye liquid indicates past infection with this pathogen. (medscimonit.com)
They therefore have a greater chance of absorbing and transmitting a pathogen than other species. (anses.fr)

We found that both the abundance of small mammal hosts and the relative abundance of the tick's natural host, the white-footed mouse ( Peromyscus leucopus ), influenced measures of disease risk in tick vectors ( Borrelia burgdorferi infection abundance and prevalence in tick vectors). (nature.com)

For example, they·re both transmitted by ticks, although by different species of ticks. (cdc.gov)

Borrelia burgdorferi Multilocus sequence typing (MLST), based on 8 chromo- somal housekeeping genes, had been carried out for several strains represented in the extracts (Table) ( 4 , 12 ). (cdc.gov)
For Borrelia burgdorferi , an hausting the alphabet, we assigned both a letter and, ar- agent of Lyme borreliosis, strains differ in their reservoir bitrarily, the number 3 (e.g. (cdc.gov)

In this case, increased host diversity may decrease the absolute abundance of white-footed mice via competition, leading to a decrease in tick abundance and the abundance of ticks infected with B. burgdorferi s.s. (nature.com)

Borrelia burgdorferi sensu lato, Coxiella burnetii, and Rickettsia spp. (medscimonit.com)

Screening dogs for exposure to Borrelia burgdorferi due to rapid geographic expansion of endemic areas. (capcvet.org)

This protein inhibits the accumulation of reactive oxygen species (ROS). (wikipedia.org)
It is based on the binding of a Borrelia protein with human fibronectin, an interaction that's key to the infection process. (acs.org)
Pine and his colleagues, including Weissman who along with Katalin Karikó was awarded the 2023 Nobel Prize in Physiology or Medicine for their work on mRNA vaccines, developed a lipid nanoparticle (LNP)-encapsulated, nucleoside-modified mRNA vaccine that encodes the outer surface protein A (OspA) from B. burgdorferi . (the-scientist.com)

1). Of the 30 Bartonella species/subspecies, 17 have been associated with human infections (2,3). (canlyme.com)
The immature larval or nymphs ticks acquire B. burgdorferi from wild rodent when feeding in nature and then transstadially transmit the infections to other hosts after these ticks molt to their subsequent developmental stage(s). (capcvet.org)
Most dogs exposed to B. burgdorferi appear to develop subclinical infections. (capcvet.org)
Serological studies have shown that infections caused by B. burgdorferi sensu lato and Bartonella sp. (medscimonit.com)
Overall, 22.7% (476/2,100) of collected ticks were tested positive for B. burgdorferi s.l. infections. (biomedcentral.com)
Comparing B. burgdorferi s.l . infections in Hanoverian I. ricinus ticks in 2010 with data from 2005, a statistically significant increase of infected larvae was noted, whereas the other stages revealed no statistically significant differences. (biomedcentral.com)

Of the 18 tick species tested, 15 species (83%) were positive for Bbsl and, of these infected ticks, 6 species bite humans. (canlyme.com)
Our data suggest that a 6-tick, enzootic maintenance cycle of Bbsl is present in southwestern B.C., and five of these tick species bite humans. (canlyme.com)
There are many species of ticks, and some species can carry and transmit dangerous diseases to humans and animals. (lebanonturf.com)
Habitat destruction and biodiversity loss,' -- driven by the replacement of local species by exotic ones, deforestation, global transportation, encroaching cities, and other environmental changes -- 'can increase the incidence and distribution of infectious diseases in humans,' write University of Vermont biologist Joe Roman, EPA scientist Montira Pongsiri, and seven co-authors in BioScience . (biologicaldiversity.org)
Although humans are accidental hosts of B. burgdorferi, nent, indicating geographic isolation. (cdc.gov)

Previous studies on detection of Trypanosoma species in Somali camels have only been performed during the 1990s using standard trypanosome detection methods (STDM). (researchgate.net)
Detection of Borrelia species, including B. burgdorferi, B. hermsii, B. parkeri, and B. turicatae by real time PCR. (tamu.edu)
Detection of Leptospira species by real time PCR. (tamu.edu)

But fragmentation and reduction of forests has led to deep declines in the number of mammals -- and white-footed mice tend to thrive in species-poor places, like small patches of forest on the edge of neighborhoods. (biologicaldiversity.org)

OH radicals and protects against brain mtDNA damage, seizures, and lipid peroxidation induced by reactive oxygen species producers. (matreya.com)
Activated inflammatory cel s, in- persistent inflammation cluding neutrophils and macrophag- es, produce reactive oxygen species and reactive nitrogen species. (who.int)

Before 1975, elements of Borrelia infection were also known as Tickborne meningopolyneuritis, Garin-Bujadoux syndrome, Bannwarth syndrome, or sheep tick fever. (newworldencyclopedia.org)

Clinical data have shown that tick-borne diseases caused by Borrelia burgdorferi sensu lato, Bartonella spp. (medscimonit.com)

In the latter year, coinfections with Borrelia and Rickettsiales were detected in a total of 7.8% (163/2,100) of collected ticks. (biomedcentral.com)

Transmission of these spirochetes can occur after the bite of a tick infected with Borrelia spirochetes. (cdc.gov)
Transmission of B. burgdorferi s.l. from ticks to hosts may occur through different developmental stages of I. ricinus, as transstadial transmission is very efficient. (biomedcentral.com)

Tick hosts differ in their efficiency as B. burgdorferi s.s. reservoirs, measured by the persistence of transmissible infection and the proportion of ticks that acquire infection after feeding upon infected host individuals. (nature.com)
Other common small mammal hosts include species of rodents and shrews that vary greatly in their competence as reservoir for B. burgdorferi s.s., from about 30% to over 50% 10 . (nature.com)

The conclusion was that positive serology alone for Borrelia does not implicate Borrelia infection in the pathogenesis of eosinophilic fasciitis in the absence of the positive demonstration of Borrelia by histochemical stains, immunohistochemical stains, or polymerase chain reaction amplification in tissue samples. (medscape.com)

Different clonal complexes may prefer molecular markers provides a more robust inference on different host species ( 9 ). (cdc.gov)

Borrelia burdorferi genotype in the northeastern United mined the MLST type of strain CA8. (cdc.gov)
Infection with B. burgdorferi is common in the northeastern, upper midwestern, and West Coast states. (capcvet.org)
The tick species most likely to carry disease are found in the northeastern quadrant of the United States. (lebanonturf.com)

Strain identifi cation of B. burgdorferi now is pre- by adding a lowercase letter, e.g. (cdc.gov)

The infected nymphal tick transmits B. burgdorferi via its saliva to the human during its blood meal. (wikipedia.org)
ticks that can transmit B. burgdorferi can be identified by the presence of an anal groove arching anterior to the anus (arrow) on the ventral surface of nymphal or adult ticks. (capcvet.org)

The strong effect of P. leucopus abundance on disease risk we report here is of significant concern, as this competent host is predicted to increase in abundance and occurrence in the region, with the northern shift in the range of North American species under climate warming. (nature.com)

The apparent clonality of B. burgdorferi was justifi cation vised names for IGS1 sequences. (cdc.gov)
2 verity and B. burgdorferi genotype ( 2 , 3 ), prediction of a IGS sequences ( 9 ). (cdc.gov)

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